Autophagic deficiency is related to steroidogenic decline in aged rat Leydig cells

Asian Journal of Andrology

Volumn 13, Issue 6, 2011, Pages 881-888

  Li, Wei Ren ^a   Chen, Liang ^b   Chang, Zhi Jie ^c   Xin, Hua ^a   Liu, Tao ^a   Zhang, Yan Quan ^c   Li, Guang Yong ^a   Zhou, Feng ^a   Gong, Yan Qing ^a   Gao, Zhe Zhu ^a   Xin, Zhong Cheng ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

^b CHINA MEITAN GENERAL HOSPITAL   (China)

^c Tsinghua University   (China)

Author keywords

ageing; autophagy; late onset hypogonadism; Leydig cell; reactive oxygen species; testosterone

Indexed keywords

BECLIN 1; LUTEINIZING HORMONE; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE; WORTMANNIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; GROUPS BY AGE; HORMONE SYNTHESIS; LEYDIG CELL; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; STEROIDOGENESIS; TESTOSTERONE BLOOD LEVEL;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BLOTTING, WESTERN; CELLS, CULTURED; GENE KNOCKDOWN TECHNIQUES; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; PHOSPHOPROTEINS; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; TESTOSTERONE;

EID: 80755167914     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2011.85     Document Type: Article

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