Substrate specificity studies of the cysteine peptidases falcipain-2 and falcipain-3 from Plasmodium falciparum and demonstration of their kininogenase activity

Molecular and Biochemical Parasitology

Volumn 187, Issue 2, 2013, Pages 111-116

  Cotrin, Simone S ^a   Gouvêa, Iuri E ^a   Melo, Pollyana M S ^a   Bagnaresi, Piero ^a   Assis, Diego M ^a   Araújo, Mariana S ^a   Juliano, Maria Aparecida ^a   Gazarini, Marcos L ^a   Rosenthal, Philip J ^b   Juliano, Luiz ^a   Carmona, Adriana K ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Falcipain; FRET substrates; Kinin releasing; Plasmodium falciparum

Indexed keywords

ALANINE; AMINOBENZOIC ACID DERIVATIVE; ARGININE; BRADYKININ; CYSTEINE PEPTIDASES FALCIPAIN 2; ETHYLENEDIAMINE DERIVATIVE; FALCIPAIN 2; FALCIPAIN 3; KALLIKREIN; KININ; KININOGEN; LEUCINE; LYSINE; METHIONINE; N [2,4 DINITROPHENYL]ETHYLENEDIAMINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MODIFICATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HYDROLYSIS; HYDROPHOBICITY; MALARIA; MOLECULAR WEIGHT; NONHUMAN; PATHOPHYSIOLOGY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN DEGRADATION; RADIOIMMUNOASSAY;

CYSTEINE ENDOPEPTIDASES; KALLIKREINS; KININOGENS; KININS; PLASMODIUM FALCIPARUM; SUBSTRATE SPECIFICITY;

EID: 84874696223     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2013.01.002     Document Type: Article

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