Protein Arginine Methyltransferase 1 Interacts with and Activates p38α to Facilitate Erythroid Differentiation

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Hua, Wei Kai ^a   Chang, Yuan I ^a   Yao, Chao Ling ^b   Hwang, Shiaw Min ^c   Chang, Chung Yi ^d   Lin, Wey Jinq ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b YUAN ZE UNIVERSITY   (Taiwan)

^c FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE   (Taiwan)

^d CHENG HSIN GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; ERYTHROID KRUPPEL LIKE FACTOR; GLYCOPHORIN A; HEMOGLOBIN; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 14; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 1; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR NF E2; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; ERYTHROID CELL; GENE SILENCING; HEMOGLOBIN SYNTHESIS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METHYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEIN TRANSPORT; TRANSCRIPTION REGULATION;

ANTIGENS, CD34; CELL DIFFERENTIATION; ENZYME ACTIVATION; ERYTHROID CELLS; ERYTHROPOIETIN; GENE KNOCKDOWN TECHNIQUES; HEMATOPOIETIC STEM CELLS; HUMANS; K562 CELLS; METHYLATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BINDING; PROTEIN-ARGININE N-METHYLTRANSFERASES; REPRESSOR PROTEINS;

EID: 84874638468     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056715     Document Type: Article

References (44)

1. Chateauvieux S, Grigorakaki C, Morceau F, Dicato M, Diederich M, (2011) Erythropoietin, erythropoiesis and beyond. Biochem Pharmacol 82: 1291-1303.
2. Elliott S, Pham E, Macdougall IC, (2008) Erythropoietins: a common mechanism of action. Exp Hematol 36: 1573-1584.
3. Schuringa JJ, Chung KY, Morrone G, Moore MA, (2004) Constitutive activation of STAT5A promotes human hematopoietic stem cell self-renewal and erythroid differentiation. J Exp Med 200: 623-635.
4. Geest CR, Coffer PJ, (2009) MAPK signaling pathways in the regulation of hematopoiesis. J Leukoc Biol 86: 237-250.
5. Bouscary D, Pene F, Claessens YE, Muller O, Chretien S, et al. (2003) Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation. Blood 101: 3436-3443.
6. Park JI, Choi HS, Jeong JS, Han JY, Kim IH, (2001) Involvement of p38 kinase in hydroxyurea-induced differentiation of K562 cells. Cell Growth Differ 12: 481-486.
7. Pace BS, Qian XH, Sangerman J, Ofori-Acquah SF, Baliga BS, et al. (2003) p38 MAP kinase activation mediates gamma-globin gene induction in erythroid progenitors. Exp Hematol 31: 1089-1096.
8. Uddin S, Ah-Kang J, Ulaszek J, Mahmud D, Wickrema A, (2004) Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cells. Proc Natl Acad Sci U S A 101: 147-152.
9. Sangerman J, Lee MS, Yao X, Oteng E, Hsiao CH, et al. (2006) Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves gamma-globin activation by CREB1 and ATF-2. Blood 108: 3590-3599.
10. Bedford MT, Clarke SG, (2009) Protein arginine methylation in mammals: who, what, and why. Mol Cell 33: 1-13.
11. Bedford MT, Richard S, (2005) Arginine methylation an emerging regulator of protein function. Mol Cell 18: 263-272.
12. Lin WJ, Gary JD, Yang MC, Clarke S, Herschman HR, (1996) The mammalian immediate-early TIS21 protein and the leukemia-associated BTG1 protein interact with a protein-arginine N-methyltransferase. J Biol Chem 271: 15034-15044.
13. Tang J, Frankel A, Cook RJ, Kim S, Paik WK, et al. (2000) PRMT1 is the predominant type I protein arginine methyltransferase in mammalian cells. J Biol Chem 275: 7723-7730.
14. Mowen KA, Schurter BT, Fathman JW, David M, Glimcher LH, (2004) Arginine methylation of NIP45 modulates cytokine gene expression in effector T lymphocytes. Mol Cell 15: 559-571.
15. Zhao X, Jankovic V, Gural A, Huang G, Pardanani A, et al. (2008) Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity. Genes Dev 22: 640-653.
16. Li X, Hu X, Patel B, Zhou Z, Liang S, et al. (2010) H4R3 methylation facilitates {beta}-globin transcription by regulating histone acetyltransferase binding and H3 acetylation. Blood 115: 2028-2037.
17. Duong FH, Christen V, Berke JM, Penna SH, Moradpour D, et al. (2005) Upregulation of protein phosphatase 2Ac by hepatitis C virus modulates NS3 helicase activity through inhibition of protein arginine methyltransferase 1. J Virol 79: 15342-15350.
18. Sakamaki J, Daitoku H, Ueno K, Hagiwara A, Yamagata K, et al. (2011) Arginine methylation of BCL-2 antagonist of cell death (BAD) counteracts its phosphorylation and inactivation by Akt. Proc Natl Acad Sci U S A 108: 6085-6090.
19. Yamagata K, Daitoku H, Takahashi Y, Namiki K, Hisatake K, et al. (2008) Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt. Mol Cell 32: 221-231.
20. Le Romancer M, Treilleux I, Leconte N, Robin-Lespinasse Y, Sentis S, et al. (2008) Regulation of estrogen rapid signaling through arginine methylation by PRMT1. Mol Cell 31: 212-221.
21. Cha B, Kim W, Kim YK, Hwang BN, Park SY, et al. (2011) Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling. Oncogene 30: 2379-2389.
22. Chang YI, Hua WK, Yao CL, Hwang SM, Hung YC, et al. (2010) Protein-arginine methyltransferase 1 suppresses megakaryocytic differentiation via modulation of the p38 MAPK pathway in K562 cells. J Biol Chem 285: 20595-20606.
23. Chang YI, Hsu SC, Chau GY, Huang CY, Sung JS, et al. (2011) Identification of the methylation preference region in heterogeneous nuclear ribonucleoprotein K by protein arginine methyltransferase 1 and its implication in regulating nuclear/cytoplasmic distribution. Biochem Biophys Res Commun 404: 865-869.
24. Chang YI, Lin SW, Chiou YY, Sung JS, Cheng LC, et al. (2010) Establishment of an ectopically expressed and functional PRMT1 for proteomic analysis of arginine-methylated proteins. Electrophoresis 31: 3834-3842.
25. Nichols RC, Wang XW, Tang J, Hamilton BJ, High FA, et al. (2000) The RGG domain in hnRNP A2 affects subcellular localization. Exp Cell Res 256: 522-532.
26. Wickrema A, Crispino JD, (2007) Erythroid and megakaryocytic transformation. Oncogene 26: 6803-6815.
27. Kyriakis JM, Avruch J, (2012) Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update. Physiol Rev 92: 689-737.
28. Wang D, Li H, Yuan H, Zheng M, Bai C, et al. (2005) Humanin delays apoptosis in K562 cells by downregulation of P38 MAP kinase. Apoptosis 10: 963-971.
29. Gump JM, Dowdy SF, (2007) TAT transduction: the molecular mechanism and therapeutic prospects. Trends Mol Med 13: 443-448.
30. Chen Z, Gibson TB, Robinson F, Silvestro L, Pearson G, et al. (2001) MAP kinases. Chem Rev 101: 2449-2476.
31. Cho JH, Lee MK, Yoon KW, Lee J, Cho SG, et al. (2012) Arginine methylation-dependent regulation of ASK1 signaling by PRMT1. Cell Death Differ 19: 859-870.
32. Tsang AP, Visvader JE, Turner CA, Fujiwara Y, Yu C, et al. (1997) FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell 90: 109-119.
33. Crossley M, Tsang AP, Bieker JJ, Orkin SH, (1994) Regulation of the erythroid Kruppel-like factor (EKLF) gene promoter by the erythroid transcription factor GATA-1. J Biol Chem 269: 15440-15444.
34. Balint BL, Szanto A, Madi A, Bauer UM, Gabor P, et al. (2005) Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells. Mol Cell Biol 25: 5648-5663.
35. Cimato TR, Tang J, Xu Y, Guarnaccia C, Herschman HR, et al. (2002) Nerve growth factor-mediated increases in protein methylation occur predominantly at type I arginine methylation sites and involve protein arginine methyltransferase 1. J Neurosci Res 67: 435-442.
36. Lim Y, Kwon YH, Won NH, Min BH, Park IS, et al. (2005) Multimerization of expressed protein-arginine methyltransferases during the growth and differentiation of rat liver. Biochim Biophys Acta 1723: 240-247.
37. Robin-Lespinasse Y, Sentis S, Kolytcheff C, Rostan MC, Corbo L, et al. (2007) hCAF1, a new regulator of PRMT1-dependent arginine methylation. J Cell Sci 120: 638-647.
38. Lei NZ, Zhang XY, Chen HZ, Wang Y, Zhan YY, et al. (2009) A feedback regulatory loop between methyltransferase PRMT1 and orphan receptor TR3. Nucleic Acids Res 37: 832-848.
39. Liu F, Zhao X, Perna F, Wang L, Koppikar P, et al. (2011) JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation. Cancer Cell 19: 283-294.
40. Higashimoto K, Kuhn P, Desai D, Cheng X, Xu W, (2007) Phosphorylation-mediated inactivation of coactivator-associated arginine methyltransferase 1. Proc Natl Acad Sci U S A 104: 12318-12323.
41. Iwasaki H, Akashi K, (2007) Myeloid lineage commitment from the hematopoietic stem cell. Immunity 26: 726-740.
42. Bouilloux F, Juban G, Cohet N, Buet D, Guyot B, et al. (2008) EKLF restricts megakaryocytic differentiation at the benefit of erythrocytic differentiation. Blood 112: 576-584.
43. Tallack MR, Perkins AC, (2009) Megakaryocyte-erythroid lineage promiscuity in EKLF null mouse blood. Haematologica 95: 144-147.
44. Guo Y, Niu C, Breslin P, Tang M, Zhang S, et al. (2009) c-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors. Blood 114: 2097-2106.