Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity

Genes and Development

Volumn 22, Issue 5, 2008, Pages 640-653

  Zhao, Xinyang ^a   Jankovic, Vladimir ^a   Gural, Alexander ^a   Huang, Gang ^a   Pardanani, Animesh ^a   Menendez, Silvia ^a   Zhang, Jin ^a   Dunne, Richard ^a   Xiao, Andrew ^b   Erdjument Bromage, Hediye ^a   Allis, C David ^b   Tempst, Paul ^a   Nimer, Stephen D ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

AML1 target genes; Arginine methylation; CD41; Myeloid differentiation; PU.1

Indexed keywords

ARGININE; ARGININE METHYLTRANSFERASE PRMT1; FIBRINOGEN RECEPTOR; HYBRID PROTEIN; METHYLTRANSFERASE; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR SIN3A; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; HEMATOPOIESIS; HUMAN; HUMAN CELL; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

ANTIGENS, CD34; ARGININE; CELL LINE, TUMOR; CORE BINDING FACTOR ALPHA 2 SUBUNIT; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HEMATOPOIESIS; HUMANS; METHYLATION; MUTATION; PLATELET MEMBRANE GLYCOPROTEIN IIB; PROTEIN-ARGININE N-METHYLTRANSFERASE; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 40349113414     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1632608     Document Type: Article

References (51)