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Volumn 10, Issue 5, 2005, Pages 963-971

Humanin delays apoptosis in K562 cells by downregulation of P38 MAP kinase

Author keywords

Apoptosis; Differentiation; Humanin; K562 cells; MAPK

Indexed keywords

HUMANIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; SORBITOL;

EID: 24644445576     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-005-1191-x     Document Type: Article
Times cited : (45)

References (37)
  • 1
    • 4243333514 scopus 로고    scopus 로고
    • A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ
    • Hashimoto Y, Niikura T, Tajima H, et al. A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ. Proc Natl Acad Sci USA 2001; 98: 6336-6341.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6336-6341
    • Hashimoto, Y.1    Niikura, T.2    Tajima, H.3
  • 2
    • 0035576106 scopus 로고    scopus 로고
    • Detailed characterization of neuroprotection by a rescue factor humanim against various Alzheimer's disease-relevant insults
    • Hashimoto Y, Niikura T, Ito Y, et al. Detailed characterization of neuroprotection by a rescue factor humanim against various Alzheimer's disease-relevant insults. J Neurosci 2001; 21: 9235-9245.
    • (2001) J Neurosci , vol.21 , pp. 9235-9245
    • Hashimoto, Y.1    Niikura, T.2    Ito, Y.3
  • 3
    • 0034805623 scopus 로고    scopus 로고
    • Mechanisms of neuroprotection by a novel rescue factor humanim from Swedish mutant amyloid precursor protein
    • Hashimoto Y, Ito Y, Niikura T, et al. Mechanisms of neuroprotection by a novel rescue factor humanim from Swedish mutant amyloid precursor protein. Biochem Biophys Res Commun 2001; 283: 460-468.
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 460-468
    • Hashimoto, Y.1    Ito, Y.2    Niikura, T.3
  • 5
    • 0035678839 scopus 로고    scopus 로고
    • [Gly(14)]-Humanin improved the learning and memory impairment induced by scopolamine in vivo
    • Mamiya T, Ukai M. [Gly(14)]-Humanin improved the learning and memory impairment induced by scopolamine in vivo. Br J Pharmacol 2001; 134: 1597-1599.
    • (2001) Br J Pharmacol , vol.134 , pp. 1597-1599
    • Mamiya, T.1    Ukai, M.2
  • 6
    • 20144387217 scopus 로고    scopus 로고
    • A Humanin derivative, S14G-HN, prevents Amyloid-β-induced memory impairment in mice
    • Tajima H, Kawasumi M, Chiba T, et al. A Humanin derivative, S14G-HN, prevents Amyloid-β-induced memory impairment in mice. J Neurosci Res 2005; 79: 714-723.
    • (2005) J Neurosci Res , vol.79 , pp. 714-723
    • Tajima, H.1    Kawasumi, M.2    Chiba, T.3
  • 7
    • 0037262465 scopus 로고    scopus 로고
    • Humanin rescues human cerebrovascular smooth muscle cells from Aβ-induced toxicity
    • Jung SS, Van Nostrand WE. Humanin rescues human cerebrovascular smooth muscle cells from Aβ-induced toxicity. J Neurochem 2003; 84: 266-272.
    • (2003) J Neurochem , vol.84 , pp. 266-272
    • Jung, S.S.1    Van Nostrand, W.E.2
  • 8
    • 2442705358 scopus 로고    scopus 로고
    • Humanim, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor
    • Ying G, Iribarren P, Zhou Y, et al. Humanim, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor. J Immunol 2004; 172: 7078-7085.
    • (2004) J Immunol , vol.172 , pp. 7078-7085
    • Ying, G.1    Iribarren, P.2    Zhou, Y.3
  • 9
    • 20244361899 scopus 로고    scopus 로고
    • Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death
    • Hashimoto Y, Tsuji O, Niikura T, et al. Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death. J Neurochem 2003; 84: 864-877.
    • (2003) J Neurochem , vol.84 , pp. 864-877
    • Hashimoto, Y.1    Tsuji, O.2    Niikura, T.3
  • 10
    • 0038485614 scopus 로고    scopus 로고
    • Humanin peptide suppresses apoptosis by interfering with Bax activation
    • Guo B, Zhai DY, Gabezas E, et al. Humanin peptide suppresses apoptosis by interfering with Bax activation. Nature 2003; 423: 456-461.
    • (2003) Nature , vol.423 , pp. 456-461
    • Guo, B.1    Zhai, D.Y.2    Gabezas, E.3
  • 12
    • 18144427811 scopus 로고    scopus 로고
    • Cytoprotective peptide Humanin binds and inhibits pro-apoptotic Bcl-2/Bax-family protein BimEL
    • AOP
    • Luciano F, Zhai D, Zhu X, et al. Cytoprotective peptide Humanin binds and inhibits pro-apoptotic Bcl-2/Bax-family protein BimEL. J Biol Chem 2005; AOP.
    • (2005) J Biol Chem
    • Luciano, F.1    Zhai, D.2    Zhu, X.3
  • 13
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signaling cascades
    • Chang L, Karin M. Mammalian MAP kinase signaling cascades. Nature 2001; 410: 37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 14
    • 0034176006 scopus 로고    scopus 로고
    • Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways
    • Witt O, Sand K, Pekrun A. Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways. Blood 2000; 95: 2391-2396.
    • (2000) Blood , vol.95 , pp. 2391-2396
    • Witt, O.1    Sand, K.2    Pekrun, A.3
  • 15
    • 0035958901 scopus 로고    scopus 로고
    • The p38 MAPK pathway mediates the growth inhibitory effects of interferon-α in BCR-ABL-expressing cells
    • Mayer IA, Verma A, Grumbach IM, et al. The p38 MAPK pathway mediates the growth inhibitory effects of interferon-α in BCR-ABL-expressing cells. J Biol Chem 2001; 276: 28570-28577.
    • (2001) J Biol Chem , vol.276 , pp. 28570-28577
    • Mayer, I.A.1    Verma, A.2    Grumbach, I.M.3
  • 16
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000; 103: 239-252.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 17
    • 0037166238 scopus 로고    scopus 로고
    • Activation of the c-Jun N-terminal kinase (JNK) signaling pathway is essential during PBOX-6-induced apoptosis in chronic myelogenous leukemia (CML) cells
    • McGee MM, Campiani G, Ramunno A, et al. Activation of the c-Jun N-terminal kinase (JNK) signaling pathway is essential during PBOX-6-induced apoptosis in chronic myelogenous leukemia (CML) cells. J Biol Chem 2002; 277: 18383-18389.
    • (2002) J Biol Chem , vol.277 , pp. 18383-18389
    • McGee, M.M.1    Campiani, G.2    Ramunno, A.3
  • 19
    • 0031671642 scopus 로고    scopus 로고
    • A newly discovered class of human hematopoietic cells with SCID-repopulating activity
    • Bhatia M, Bonnet D, Murdoch B. A newly discovered class of human hematopoietic cells with SCID-repopulating activity. Nat Med 1998; 4: 1038-1045.
    • (1998) Nat Med , vol.4 , pp. 1038-1045
    • Bhatia, M.1    Bonnet, D.2    Murdoch, B.3
  • 21
    • 0034001970 scopus 로고    scopus 로고
    • The inhibition of ERK/MAPK not the activation of JNK/SAPK is primarily required to induce apoptosis in chronic myelogenous leukemic K562 cells
    • Kang CD, Yoo SD, Hwang BW, et al. The inhibition of ERK/MAPK not the activation of JNK/SAPK is primarily required to induce apoptosis in chronic myelogenous leukemic K562 cells. Leukemia Res 2000; 24: 527-534.
    • (2000) Leukemia Res , vol.24 , pp. 527-534
    • Kang, C.D.1    Yoo, S.D.2    Hwang, B.W.3
  • 22
    • 0038447079 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate promotes mouse melanocyte survival via ERK and Akt activation
    • Kim DS, Hwang ES, Lee JE, Kim SY, Park KC. Sphingosine-1-phosphate promotes mouse melanocyte survival via ERK and Akt activation. Cell Signal 2003; 15: 919-926.
    • (2003) Cell Signal , vol.15 , pp. 919-926
    • Kim, D.S.1    Hwang, E.S.2    Lee, J.E.3    Kim, S.Y.4    Park, K.C.5
  • 23
    • 0030866934 scopus 로고    scopus 로고
    • Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells
    • Racke FK, Lewandowska K, Goueli S, Goldfarb AN. Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells. J Biol Chem 1997; 272: 23366-23370.
    • (1997) J Biol Chem , vol.272 , pp. 23366-23370
    • Racke, F.K.1    Lewandowska, K.2    Goueli, S.3    Goldfarb, A.N.4
  • 24
    • 0035800782 scopus 로고    scopus 로고
    • Stromal inhibition of megakaryocytic differentiation correlates with blockade of signaling by protein kinase C-ε and ERK/MAPK
    • Goldfarb AN, Delehanty LL, Wang D, Racke FK, Hussaini IM. Stromal inhibition of megakaryocytic differentiation correlates with blockade of signaling by protein kinase C-ε and ERK/MAPK. J Biol Chem 2001; 276: 29526-29530.
    • (2001) J Biol Chem , vol.276 , pp. 29526-29530
    • Goldfarb, A.N.1    Delehanty, L.L.2    Wang, D.3    Racke, F.K.4    Hussaini, I.M.5
  • 26
    • 14644407525 scopus 로고    scopus 로고
    • The role of apoptosis in cancer development and treatment response
    • Brown JM, Attardi LD. The role of apoptosis in cancer development and treatment response. Nat Rev Cancer 2005; 5: 231-237.
    • (2005) Nat Rev Cancer , vol.5 , pp. 231-237
    • Brown, J.M.1    Attardi, L.D.2
  • 27
    • 1542615077 scopus 로고    scopus 로고
    • A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: Involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation
    • Miyoshi N, Uchida K, Osawa T, Nakamura Y. A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: Involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation. Cancer Res 2004; 64: 2134-2142.
    • (2004) Cancer Res , vol.64 , pp. 2134-2142
    • Miyoshi, N.1    Uchida, K.2    Osawa, T.3    Nakamura, Y.4
  • 28
    • 0038691851 scopus 로고    scopus 로고
    • Decitabine induces cell cycle arrest at the G1 phase via p21 (WAF1) and the G2/M phase via the p38 MAP kinase pathway
    • Lavelle D, DeSimone J, Hankewych M, Kousnetzova T, Chen YH. Decitabine induces cell cycle arrest at the G1 phase via p21 (WAF1) and the G2/M phase via the p38 MAP kinase pathway. Leuk Res 2003; 27: 999-1007.
    • (2003) Leuk Res , vol.27 , pp. 999-1007
    • Lavelle, D.1    Desimone, J.2    Hankewych, M.3    Kousnetzova, T.4    Chen, Y.H.5
  • 30
    • 0037938663 scopus 로고    scopus 로고
    • Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: Identification of an Achilles heel in leukemia
    • Blalock WL, Navolanic PM, Steelman LS, et al. Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: Identification of an Achilles heel in leukemia. Leukemia 2003; 17: 1058-1067.
    • (2003) Leukemia , vol.17 , pp. 1058-1067
    • Blalock, W.L.1    Navolanic, P.M.2    Steelman, L.S.3
  • 31
    • 11144297712 scopus 로고    scopus 로고
    • Fucoidan induces apoptosis of human HS-sultan cells accompanied by activation of caspase-3 and downregulation of ERK pathways
    • Aisa Y, Miyakawa Y, Nakazato T, et al. Fucoidan induces apoptosis of human HS-sultan cells accompanied by activation of caspase-3 and downregulation of ERK pathways. Am J Hematol 2005; 78: 7-14.
    • (2005) Am J Hematol , vol.78 , pp. 7-14
    • Aisa, Y.1    Miyakawa, Y.2    Nakazato, T.3
  • 32
    • 0141502208 scopus 로고    scopus 로고
    • Downmodulation of ERK activity inhibits the proliferation and induces the apoptosis of primary acute myelogenous leukemia blasts
    • Lunghi P, Tabilio A, Dall'Aglio PP, et al. Downmodulation of ERK activity inhibits the proliferation and induces the apoptosis of primary acute myelogenous leukemia blasts. Leukemia 2003; 17: 1783-1793.
    • (2003) Leukemia , vol.17 , pp. 1783-1793
    • Lunghi, P.1    Tabilio, A.2    Dall'Aglio, P.P.3
  • 33
    • 0037226583 scopus 로고    scopus 로고
    • Role of apical caspases and glucocorticoid-regulated genes in glucocorticoid-induced apoptosis of pre-B leukemic cells
    • Planey SL, Abrams MT, Robertson NM, Litwack G. Role of apical caspases and glucocorticoid-regulated genes in glucocorticoid-induced apoptosis of pre-B leukemic cells. Cancer Res 2003; 63: 172-178.
    • (2003) Cancer Res , vol.63 , pp. 172-178
    • Planey, S.L.1    Abrams, M.T.2    Robertson, N.M.3    Litwack, G.4
  • 34
    • 0038400952 scopus 로고    scopus 로고
    • C-Jun N-terminal kinases/c-Jun and p38 pathways cooperate in ceramide-induced neuronal apoptosis
    • Willaime-Morawek S, Brami-Cherrier K, Mariani J, Caboche J, Brugg B. C-Jun N-terminal kinases/c-Jun and p38 pathways cooperate in ceramide-induced neuronal apoptosis. Neuroscience 2003; 119: 387-397.
    • (2003) Neuroscience , vol.119 , pp. 387-397
    • Willaime-Morawek, S.1    Brami-Cherrier, K.2    Mariani, J.3    Caboche, J.4    Brugg, B.5
  • 35
    • 0033804915 scopus 로고    scopus 로고
    • K562 cells resistant to phorbol 12-myristate 13-acetate-induced growth arrest: Dissociation of mitogen-activated protein kinase activation and Egr-1 expression from megakaryocyte differentiation
    • Shelly C, Petruzzelli L, Herrera R. K562 cells resistant to phorbol 12-myristate 13-acetate-induced growth arrest: Dissociation of mitogen-activated protein kinase activation and Egr-1 expression from megakaryocyte differentiation. Cell Growth Differ 2000; 11: 501-506.
    • (2000) Cell Growth Differ , vol.11 , pp. 501-506
    • Shelly, C.1    Petruzzelli, L.2    Herrera, R.3
  • 36
    • 8544252411 scopus 로고    scopus 로고
    • Clinical strategies for expansion of haematopoietic stem cells
    • Sorrentino BP. Clinical strategies for expansion of haematopoietic stem cells. Nat Rev Immunol 2004; 4: 878-888.
    • (2004) Nat Rev Immunol , vol.4 , pp. 878-888
    • Sorrentino, B.P.1
  • 37
    • 0034684662 scopus 로고    scopus 로고
    • Hematopoietic stem cells need two signals to prevent apoptosis; Bcl-2 can provide one of these, Kitl/c-Kit signaling the other
    • Domen J, Weissman IL. Hematopoietic stem cells need two signals to prevent apoptosis; Bcl-2 can provide one of these, Kitl/c-Kit signaling the other. J Exp Med 2000; 192: 1707-1718
    • (2000) J Exp Med , vol.192 , pp. 1707-1718
    • Domen, J.1    Weissman, I.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.