Icariin promotes histone acetylation and attenuates post-stroke cognitive impairment in the central cholinergic circuits of mice

Neuroscience

Volumn 236, Issue , 2013, Pages 281-288

  Wang, X ^a,b   Li, J ^c,d   Qian, L ^c,d   Zang, X F ^c,d   Zhang, S Y ^c,d   Wang, X Y ^a,c,d   Jin, J L ^c,d   Zhu, X L ^c,d   Zhang, X B ^b   Wang, Z Y ^c,d   Xu, Y ^a,c,d  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b CLINICAL MEDICAL COLLEGE OF YANGZHOU UNIVERSITY   (China)

^c THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^d NANJING UNIVERSITY   (China)

Author keywords

Cholinergic nerve circuits; Histone acetylation homeostasis; ICA; Mice; Phosphorylated CREB; Post stroke dementia

Indexed keywords

ACETYLCHOLINE; CHOLINE ACETYLTRANSFERASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ICARIIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CEREBROVASCULAR ACCIDENT; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DEMENTIA; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG STRUCTURE; HISTONE ACETYLATION; IMMUNOFLUORESCENCE; LATENT PERIOD; MALE; MAZE TEST; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; POSTSTROKE DEMENTIA; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SPATIAL LEARNING; SPATIAL MEMORY; WESTERN BLOTTING;

ACETYLATION; ACETYLCHOLINE; ANIMALS; BLOTTING, WESTERN; BRAIN; DEMENTIA; DISEASE MODELS, ANIMAL; FLAVONOIDS; HISTONES; MALE; MAZE LEARNING; MICE; NEURAL PATHWAYS; NEUROPROTECTIVE AGENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STROKE;

EID: 84874532719     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.12.074     Document Type: Article

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