In vivo functional evaluation of central cholinergic circuits in vascular dementia

Clinical Neurophysiology

Volumn 119, Issue 11, 2008, Pages 2494-2500

  Di Lazzaro, V ^a   Pilato, F ^a   Dileone, M ^a   Profice, P ^a   Marra, C ^a   Ranieri, F ^a   Quaranta, D ^a   Gainotti, G ^a   Tonali, P A ^a,b  

^a CATHOLIC UNIVERSITY   (Italy)

^b IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

Author keywords

Alzheimer disease; Cholinergic circuits; Transcranial magnetic stimulation; Vascular dementia

Indexed keywords

AGED; ARTICLE; CHOLINERGIC ACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DIFFERENTIAL DIAGNOSIS; EVALUATION; FEMALE; HUMAN; IN VIVO STUDY; MALE; MULTIINFARCT DEMENTIA; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL;

ACETYLCHOLINE; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; BRAIN; CASE-CONTROL STUDIES; DEMENTIA, VASCULAR; EVALUATION STUDIES AS TOPIC; EVOKED POTENTIALS, MOTOR; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; NERVE NET; NEURAL INHIBITION; NEUROPSYCHOLOGICAL TESTS; REACTION TIME; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 54149112117     PISSN: 13882457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinph.2008.08.010     Document Type: Article

References (64)

1. Alagona G., Bella R., Ferri R., Carnemolla A., Pappalardo A., Costanzo E., et al. Transcranial magnetic stimulation in Alzheimer disease: motor cortex excitability and cognitive severity. Neurosci Lett 314 (2001) 57-60
2. Bartus R.T. On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis. Exp Neurol 163 (2000) 495-529
3. Butefisch C.M., Netz J., Wessling M., Seitz R.J., and Homberg V. Remote changes in cortical excitability after stroke. Brain 126 (2003) 470-481
4. Carlesimo G.A., Caltagirone C., and Gainotti G. The Mental Deterioration Battery: normative data, diagnostic reliability and qualitative analyses of cognitive impairment. The group for the standardization of the Mental deterioration battery. Eur Neurol 36 (1996) 378-384
5. Coyle J.T., Price D.L., and DeLong M.R. Alzheimer's disease: a disorder of cortical cholinergic innervation. Science 219 (1983) 1184-1190
6. Davies P., and Maloney A.J. Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet 2 8000 (1976) 1403
7. de Carvalho M., de Mendonca A., Miranda P.C., Garcia C., and Luis M.L. Magnetic stimulation in Alzheimer's disease. J Neurol 244 (1997) 304-307
8. Desmond D.W. The neuropsychology of vascular cognitive impairment: is there a specific cognitive deficit?. J Neurol Sci 226 (2004) 3-7
9. Di Lazzaro V., Oliviero A., Meglio M., Cioni B., Tamburrini G., Tonali P., et al. Direct demonstration of the effect of lorazepam on the excitability of the human motor cortex. Clin Neurophysiol 111 (2000) 794-799
10. Di Lazzaro V., Oliviero A., Pilato F., Saturno E., Dileone M., Marra C., et al. Motor cortex hyperexcitability to transcranial magnetic stimulation in Alzheimer's disease. J Neurol Neurosurg Psychiat 75 (2004) 555-559
11. Di Lazzaro V., Oliviero A., Pilato F., Saturno E., Dileone M., Marra C., et al. Neurophysiological predictors of long term response to AChE inhibitors in AD patients. J Neurol Neurosurg Psychiatry 76 (2005) 1064-1069
12. Di Lazzaro V., Oliviero A., Pilato F., Saturno E., Dileone M., and Tonali P.A. Motor cortex hyperexcitability to transcranial magnetic stimulation in Alzheimer's disease: evidence of impaired glutamatergic neurotransmission?. Ann Neurol 53 (2003) 824
13. Di Lazzaro V., Oliviero A., Profice P., Pennisi M.A., Di Giovanni S., Zito G., et al. Muscarinic receptor blockade has differential effects on the excitability of intracortical circuits in the human motor cortex. Exp Brain Res 135 (2000) 455-461
14. Di Lazzaro V., Oliviero A., Pilato F., Saturno E., Dileone M., Mazzone P., et al. The physiological basis of transcranial motor cortex stimulation in conscious humans. Clin Neurophysiol 115 (2004) 255-266
15. Di Lazzaro V., Oliviero A., Saturno E., Dileone M., Pilato F., Nardone R., et al. Effects of lorazepam on short latency afferent inhibition and short latency intracortical inhibition in humans. J Physiol 564 (2005) 661-668
16. Di Lazzaro V., Oliviero A., Tonali P.A., Marra C., Daniele A., Profice P., et al. Non-invasive in vivo assessment of cholinergic cortical circuits in Alzheimer's disease using transcranial magnetic stimulation. Neurology 59 (2002) 392-397
17. Di Lazzaro V., Pilato F., Dileone M., Saturno E., Oliviero A., Marra C., et al. In vivo cholinergic circuit evaluation in frontotemporal and Alzheimer dementias. Neurology 66 (2006) 1111-1113
18. Di Lazzaro V., Pilato F., Dileone M., Saturno E., Profice P., Marra C., et al. Functional evaluation of cerebral cortex in dementia with Lewy bodies. Neuroimage 37 (2007) 422-429
19. Di Lazzaro V., Pilato F., Dileone M., Tonali P.A., and Ziemann U. Dissociated effects of diazepam and lorazepam on short-latency afferent inhibition. J Physiol 569 (2005) 315-323
20. Di Lazzaro V., Pilato F., Dileone M., Profice P., Ranieri F., Ricci V., et al. Segregating two inhibitory circuits in human motor cortex at the level of GABAA receptor subtypes: a TMS study. Clin Neurophysiol 118 (2007) 2207-2214
21. Esiri M.M., Wilcock G.K., and Morris J.H. Neuropathological assessment of the lesions of significance in vascular dementia. J Neurol Neurosurg Psychiatry 63 (1997) 749-753
22. Ferreri F., Pauri F., Pasqualetti P., Fini R., Dal Forno G., and Rossini P.M. Motor cortex excitability in Alzheimer's disease: a transcranial magnetic stimulation study. Ann Neurol 53 (2003) 102-108
23. Fisher R.J., Nakamura Y., Bestmann S., Rothwell J.C., and Bostock H. Two phases of intracortical inhibition revealed by transcranial magnetic threshold tracking. Exp Brain Res 143 (2002) 240-248
24. Fujiki M., Hikawa T., Abe T., Ishii K., and Kobayashi H. Reduced short latency afferent inhibition in diffuse axonal injury patients with memory impairment. Neurosci Lett 405 (2006) 226-230
25. Gainotti G., Marra C., and Villa G.P. A double dissociation between accuracy and time of execution on attentional tasks in Alzheimer" disease and multi-infarct dementia. Brain 124 (2001) 731-738
26. Geula C., and Mesulam M.-M. Cholinergic systems in Alzheimer's disease. In: Terry R.D., Katzman R., Bick K.L., and Sisodia S.S. (Eds). Alzheimer disease. 2nd ed. (1999), Lippincott, Williams & Wilkins, Philadelphia
27. Gold G., Kovari E., Herrmann F.R., Canuto A., Hof P.R., Michel J.P., et al. Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia. Stroke 36 (2005) 1184-1188
28. Graham N.L., Emery T., and Hodges J.R. Distinctive cognitive profiles in Alzheimer's disease and subcortical vascular dementia. J Neurol Neurosurg Psychiatry 75 (2004) 61-71
29. Hachinski V.C., Iliff L.D., Zilhka E., Du Boulay G.H., McAllister V.L., Marshall J., et al. Cerebral blood flow in dementia. Arch Neurol 32 (1975) 632-637
30. Hanajima R., Furubayashi T., Iwata N.K., Shiio Y., Okabe S., Kanazawa I., et al. Further evidence to support different mechanisms underlying intracortical inhibition of the motor cortex. Exp Brain Res 151 (2003) 427-434
31. Hasselmo M.E., and Bower J.M. Acetylcholine and memory. Trends Neurosci 16 (1993) 218-222
32. Heyman A., Fillenbaum G.G., Welsh-Bohmer K.A., Gearing M., Mirra S.S., Mohs R.C., et al. Cerebral infarcts in patients with autopsy-proven Alzheimer's disease, CERAD Part XVIII. Neurology 51 (1998) 159-162
33. Ihara M., Tomimoto H., Ishizu K., Mukai T., Yoshida H., Sawamoto N., et al. Decrease in cortical benzodiazepine receptors in symptomatic patients with leukoaraiosis: a positron emission tomography study. Stroke 35 (2004) 942-947
34. Kalaria R.N., and Ballard K. Overlap between pathology of Alzheimer disease and vascular dementia. Alzheimer Dis Relat Disord 13 (1999) S115-S123
35. Kovari E., Gold G., Herrmann F.R., Canuto A., Hof P.R., Michel J.P., et al. Cortical microinfarcts and demyelination significantly affect cognition in brain aging. Stroke 35 (2004) 410-414
36. Kujirai T., Caramia M.D., Rothwell J.C., Day B.L., Thompson P.D., Ferbert A., et al. Corticocortical inhibition in human motor cortex. J Physiol (Lond) 471 (1993) 501-519
37. Liepert J., Bar K.J., Meske U., and Weiller C. Motor cortex disinhibition in Alzheimer's disease. Clin Neurophysiol 112 (2001) 1436-1441
38. Liepert J., Restemeyer C., Kucinski T., Zittel S., and Weiller C. Motor strokes: the lesion location determines motor excitability changes. Stroke 36 (2005) 2648-2653
39. Manganelli F., Ragno M., Cacchiò G., Iodice V., Trojano L., Silvaggio F., et al. Motor cortex cholinergic dysfunction in CADASIL: a transcranial magnetic demonstration. Clin Neurophysiol 119 (2008) 351-355
40. McKhann G., Drachman D., Folstein M., Katzman R., Price D., and Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 34 (1984) 939-944
41. Mesulam M., Siddique T., and Cohen B. Cholinergic denervation in a pure multi-infarct state: observations on CADASIL. Neurology (2003) 1183-1185
42. Mittmann T., Qu M., Zilles K., and Luhmann H.J. Long-term cellular dysfunction after focal cerebral ischemia: in vitro analyses. Neuroscience 85 (1998) 15-27
43. Nagy Z., Esiri M.M., Joachim C., Jobst K.A., Morris J.H., King E.M., et al. Comparison of pathological diagnostic criteria for Alzheimer disease. Alzheimer Dis Assoc Disord 12 (1998) 182-189
44. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Lancet 2001;357: 169-75.
45. Pepin J.L., Bogacz D., de Pasqua V., and Delwaide P.J. Motor cortex inhibition is not impaired in patients with Alzheimer's disease: evidence from paired transcranial magnetic stimulation. J Neurol Sci 170 (1999) 119-123
46. Perret E. The left frontal lobe of man and the suppression of habitual responses in verbal categorical behaviour. Neuropsychologia 12 (1974) 323-330
47. Perry E., Ziabreva I., Perry R., Aarsland D., and Ballard C. Absence of cholinergic deficits in "pure" vascular dementia. Neurology 64 (2005) 132-133
48. Pierantozzi M., Panella M., Palmieri M.G., Koch G., Giordano A., Marciani M.G., et al. Different TMS patterns of intracortical inhibition in early onset Alzheimer dementia and frontotemporal dementia. Clin Neurophysiol 115 (2004) 2410-2418
49. Premkumar D.R.D., Cohen D.L., Hedera P., Friedland R.P., and Kalaria R.N. Apolipoprotein 4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology in Alzheimer's disease. Am J Pathol 148 (1996) 2083-2095
50. Reisberg B., Ferris S.H., de Leon M.J., and Crook T. The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry 139 (1982) 1136-1139
51. Raven JC. Progressive matrices (1947), Sets A, Ab, B: board and book forms, London, Lewis, 1949.
52. Reed B.R., Mungas D.M., Kramer J.H., Ellis W., Vinters H.V., Zarow C., et al. Profiles of neuropsychological impairment in autopsy-defined Alzheimer's disease and cerebrovascular disease. Brain 130 (2007) 731-739
53. Rey A. Mèmorisation d'une sèrie de 15 mots en 5 rèpètitions. In: Rey A. (Ed). L'examen clinique en psychologie (1958), Presses Universitaires de France, Paris
54. Roman G.C., and Kalaria R.N. Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia. Neurobiol Aging 27 (2006) 1769-1785
55. Roman G.C., Sachdev P., Royall D.R., Bullock R.A., Orgogozo J.M., Lopez-Pousa S., et al. Vascular cognitive disorder: a new diagnostic category updating vascular cognitive impairment and vascular dementia. J Neurol Sci 226 (2004) 81-87
56. Roman G.C., Tatemichi T.K., Erkinjuntti T., Cummings J.L., Masdeu J.C., Garcia J.H., et al. Vascular dementia: diagnostic criteria for research studies Report of the NINDS-AIREN International Workshop. Neurology 43 (1993) 250-260
57. Talelli P., Greenwood R.J., and Rothwell J.C. Arm function after stroke: neurophysiological correlates and recovery mechanisms assessed by transcranial magnetic stimulation. Clin Neurophysiol 117 (2006) 1641-1659
58. Tokimura H., Di Lazzaro V., Tokimura Y., Oliviero A., Profice P., Insola A., et al. Short latency inhibition of human hand motor cortex by somatosensory input from the hand. J Physiol 523 (2000) 503-513
59. Vinters H.V., Ellis W.G., Zarow C., Zaias B.W., Jagust W.J., Mack W.J., et al. Neuropathological substrates of ischemic vascular dementia. J Neuropathol Exp Neurol 59 (2000) 931-945
60. Whitehouse P.J., Price D.L., Struble R.G., Clark A.W., Coyle J.T., and Delon M.R. Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science 215 (1982) 1237-1239
61. Whitwell J.L., Przybelski S.A., Weigand S.D., Knopman D.S., Boeve B.F., Petersen R.C., et al. 3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease. Brain 130 (2007) 1777-1786
62. Ziemann U., Lonnecker S., Steinhof B.J., and Paulus W. The effect of lorazepam on the motor cortical excitability in man. Exp Brain Res 109 (1996) 127-135
63. Ziemann U., Lonnecker S., Steinhoff B.J., and Paulus W. Effects of antiepileptics drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study. Ann Neurol 40 (1996) 367-378
64. Ziemann U. TMS and drugs. Clin Neurophysiol 115 (2004) 1717-1729