Icariin inhibits hydrogen peroxide-mediated cytotoxicity by up-regulating sirtuin type 1-dependent catalase and peroxiredoxin

Basic and Clinical Pharmacology and Toxicology

Volumn 107, Issue 5, 2010, Pages 899-905

  Zhang, Ling ^a   Huang, Siyuan ^a   Chen, Yanting ^a   Wang, Zhongyuan ^a,b   Li, Erguang ^a,b   Xu, Yun ^a,b  

^a THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; HYDROGEN PEROXIDE; ICARIIN; PEROXIREDOXIN 1; SIRTUIN 1;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG MECHANISM; EMBRYO; ENZYME ACTIVITY; IMMUNOBLOTTING; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STROKE; UPREGULATION;

ANIMALS; APOPTOSIS; CATALASE; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; HYDROGEN PEROXIDE; MICE; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PEROXIREDOXINS; REAL-TIME POLYMERASE CHAIN REACTION; SIRTUIN 1; SPECTROPHOTOMETRY; UP-REGULATION;

EID: 78649601721     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2010.00595.x     Document Type: Article

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