SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity

Laboratory Investigation

Volumn 91, Issue 12, 2011, Pages 1796-1804

  Nakatsugawa, Munehide ^a   Takahashi, Akari ^a   Hirohashi, Yoshihiko ^a   Torigoe, Toshihiko ^a   Inoda, Satoko ^a   Murase, Masaki ^a   Asanuma, Hiroko ^a   Tamura, Yasuaki ^a   Morita, Rena ^a   Michifuri, Yoshitaka ^a   Kondo, Toru ^b   Hasegawa, Tadashi ^a   Takahashi, Hiroki ^a   Sato, Noriyuki ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b EHIME UNIVERSITY   (Japan)

Author keywords

cancer stem cell; lung cancer; SOX2; SP cell; tumorigenicity

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR SOX2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER STEM CELL; CARCINOGENICITY; CARCINOMA CELL; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ADENOCARCINOMA; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DOWN-REGULATION; FEMALE; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED NOD; MICE, SCID; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; PHENOTYPE; RNA, SMALL INTERFERING; SIDE-POPULATION CELLS; SOXB1 TRANSCRIPTION FACTORS;

EID: 82355171754     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2011.140     Document Type: Article

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