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Volumn 35, Issue 1, 2013, Pages 2-21

Vitamin B12 intake and status and cognitive function in elderly people

Author keywords

aged; cognition; dementia; nutritional requirements; recommended dietary allowances; review

Indexed keywords

CYANOCOBALAMIN; METHYLMALONIC ACID; TRANSCOBALAMIN;

EID: 84874453926     PISSN: 0193936X     EISSN: 14786729     Source Type: Journal    
DOI: 10.1093/epirev/mxs003     Document Type: Article
Times cited : (50)

References (84)
  • 1
    • 34047124264 scopus 로고    scopus 로고
    • Nutrient risk assessment: Setting upper levels and an opportunity for harmonization
    • Aggett PJ. Nutrient risk assessment: setting upper levels and an opportunity for harmonization. Food Nutr Bull. 2007; 28(suppl 1):S27-S37.
    • (2007) Food Nutr Bull. , vol.28 , Issue.SUPPL. 1
    • Aggett, P.J.1
  • 2
    • 77953209570 scopus 로고    scopus 로고
    • European micronutrient recommendations aligned: A general framework developed by EURRECA
    • Dhonukshe-Rutten RAM, Timotijevic L, Cavelaars A, et al. European micronutrient recommendations aligned: a general framework developed by EURRECA. Eur J Clin Nutr. 2010;64(suppl 2):S2-S10.
    • (2010) Eur J Clin Nutr. , vol.64 , Issue.SUPPL. 2
    • Dhonukshe-Rutten, R.A.M.1    Timotijevic, L.2    Cavelaars, A.3
  • 4
    • 34047124263 scopus 로고    scopus 로고
    • Determining life-stage groups and extrapolating nutrient intake values (NIVs)
    • Atkinson SA, Koletzko B. Determining life-stage groups and extrapolating nutrient intake values (NIVs). Food Nutr Bull. 2007;28(suppl 1):S61-S76.
    • (2007) Food Nutr Bull. , vol.28 , Issue.SUPPL. 1
    • Atkinson, S.A.1    Koletzko, B.2
  • 5
    • 61449121062 scopus 로고    scopus 로고
    • Opportunities and challenges in conducting systematic reviews to support the development of nutrient reference values: Vitamin A as an example
    • Russell R, Chung M, Balk EM, et al. Opportunities and challenges in conducting systematic reviews to support the development of nutrient reference values: vitamin A as an example. Am J Clin Nutr. 2009;89(3):728-733.
    • (2009) Am J Clin Nutr. , vol.89 , Issue.3 , pp. 728-733
    • Russell, R.1    Chung, M.2    Balk, E.M.3
  • 6
    • 0034685429 scopus 로고    scopus 로고
    • Meta-analysis of observational studies in epidemiology: A proposal for reporting. Meta-analysis of Observational Studies in Epidemiology (MOOSE) group
    • Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000;283(15):2008- 2012.
    • (2000) JAMA , vol.283 , Issue.15 , pp. 2008-2012
    • Stroup, D.F.1    Berlin, J.A.2    Morton, S.C.3
  • 7
    • 33846037713 scopus 로고    scopus 로고
    • 12 and folic acid supplementation and cognitive function: A systematic review of randomized trials
    • 12, and folic acid supplementation and cognitive function: a systematic review of randomized trials. Arch Intern Med. 2007; 167(1):21-30.
    • (2007) Arch Intern Med. , vol.167 , Issue.1 , pp. 21-30
    • Balk, E.M.1    Raman, G.2    Tatsioni, A.3
  • 8
    • 4344665176 scopus 로고    scopus 로고
    • A critical evaluation of the relationship between serum vitamin B-12, folate and total homocysteine with cognitive impairment in the elderly
    • Ellinson M, Thomas J, Patterson A. A critical evaluation of the relationship between serum vitamin B-12, folate and total homocysteine with cognitive impairment in the elderly. J Hum Nutr Diet. 2004;17(4):371-383.
    • (2004) J Hum Nutr Diet. , vol.17 , Issue.4 , pp. 371-383
    • Ellinson, M.1    Thomas, J.2    Patterson, A.3
  • 10
    • 34447116945 scopus 로고    scopus 로고
    • Heterogeneity and lack of good quality studies limit association between folate, vitamins B-6 and B-12, and cognitive function
    • Raman G, Tatsioni A, Chung M, et al. Heterogeneity and lack of good quality studies limit association between folate, vitamins B-6 and B-12, and cognitive function. J Nutr. 2007;137(7):1789-1794.
    • (2007) J Nutr. , vol.137 , Issue.7 , pp. 1789-1794
    • Raman, G.1    Tatsioni, A.2    Chung, M.3
  • 11
    • 67650729820 scopus 로고    scopus 로고
    • 12, folate and cognitive functions: A systematic and critical review of the literature
    • 12, folate and cognitive functions: a systematic and critical review of the literature. Int J Clin Pract. 2009; 63(7):1061-1067.
    • (2009) Int J Clin Pract. , vol.63 , Issue.7 , pp. 1061-1067
    • Vogel, T.1    Dali-Youcef, N.2    Kaltenbach, G.3
  • 12
    • 77952990224 scopus 로고    scopus 로고
    • Effect of folic acid, with or without other B vitamins, on cognitive decline: Meta-analysis of randomized trials
    • Wald DS, Kasturiratne A, Simmonds M. Effect of folic acid, with or without other B vitamins, on cognitive decline: meta-analysis of randomized trials. Am J Med. 2010; 123(6):522-527.
    • (2010) Am J Med. , vol.123 , Issue.6 , pp. 522-527
    • Wald, D.S.1    Kasturiratne, A.2    Simmonds, M.3
  • 13
    • 0016823810 scopus 로고
    • "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-198.
    • (1975) J Psychiatr Res. , vol.12 , Issue.3 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 15
    • 66849106748 scopus 로고    scopus 로고
    • Studies of biomarker responses to intervention with vitamin B-12: A systematic review of randomized controlled trials
    • Hoey L, Strain JJ, McNulty H. Studies of biomarker responses to intervention with vitamin B-12: a systematic review of randomized controlled trials. Am J Clin Nutr. 2009;89(6):1981S-1996S.
    • (2009) Am J Clin Nutr. , vol.89 , Issue.6
    • Hoey, L.1    Strain, J.J.2    McNulty, H.3
  • 16
    • 79959460458 scopus 로고    scopus 로고
    • Holotranscobalamin, a marker of vitamin B-12 status: Analytical aspects and clinical utility
    • Nexo E, Hoffmann-Lucke E. Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility. Am J Clin Nutr. 2011;94(1):359S-365S.
    • (2011) Am J Clin Nutr. , vol.94 , Issue.1
    • Nexo, E.1    Hoffmann-Lucke, E.2
  • 19
    • 28444460680 scopus 로고    scopus 로고
    • Reduced risk of Alzheimer's disease with high folate intake: The Baltimore Longitudinal Study of Aging
    • Corrada MM, Kawas CH, Hallfrisch J, et al. Reduced risk of Alzheimer's disease with high folate intake: the Baltimore Longitudinal Study of Aging. Alzheimers Dement. 2005; 1(1):1118.
    • (2005) Alzheimers Dement. , vol.1 , Issue.1 , pp. 1118
    • Corrada, M.M.1    Kawas, C.H.2    Hallfrisch, J.3
  • 20
    • 33747405540 scopus 로고    scopus 로고
    • Dietary folate and vitamins B-12 and B-6 not associated with incident Alzheimer's disease
    • Morris MC, Evans DA, Schneider JA, et al. Dietary folate and vitamins B-12 and B-6 not associated with incident Alzheimer's disease. J Alzheimers Dis. 2006;9(4):435-443.
    • (2006) J Alzheimers Dis. , vol.9 , Issue.4 , pp. 435-443
    • Morris, M.C.1    Evans, D.A.2    Schneider, J.A.3
  • 21
    • 74049154169 scopus 로고    scopus 로고
    • Dietary folate, vitamin B-12, vitamin B-6 and incident Alzheimer's disease: The Cache County Memory, Health and Aging Study
    • Nelson C, Wengreen HJ, Munger RG, et al. Dietary folate, vitamin B-12, vitamin B-6 and incident Alzheimer's disease: the Cache County Memory, Health and Aging Study. J Nutr Health Aging. 2009;13(10):899-905.
    • (2009) J Nutr Health Aging. , vol.13 , Issue.10 , pp. 899-905
    • Nelson, C.1    Wengreen, H.J.2    Munger, R.G.3
  • 22
    • 33846875849 scopus 로고    scopus 로고
    • Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: Results from the Sacramento Area Latino Study on Aging
    • Haan MN, Miller JW, Aiello AE, et al. Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging. Am J Clin Nutr. 2007;85(2):511-517.
    • (2007) Am J Clin Nutr. , vol.85 , Issue.2 , pp. 511-517
    • Haan, M.N.1    Miller, J.W.2    Aiello, A.E.3
  • 24
    • 27244445944 scopus 로고    scopus 로고
    • Homocysteine and folate as risk factors for dementia and Alzheimer disease
    • Ravaglia G, Forti P, Maioli F, et al. Homocysteine and folate as risk factors for dementia and Alzheimer disease. Am J Clin Nutr. 2005;82(3):636-643.
    • (2005) Am J Clin Nutr. , vol.82 , Issue.3 , pp. 636-643
    • Ravaglia, G.1    Forti, P.2    Maioli, F.3
  • 25
    • 0035826810 scopus 로고    scopus 로고
    • 12 and folate in relation to the development of Alzheimer's disease
    • 12 and folate in relation to the development of Alzheimer's disease. Neurology. 2001;56(9):1188-1194.
    • (2001) Neurology. , vol.56 , Issue.9 , pp. 1188-1194
    • Wang, H.X.1    Wahlin, A.2    Basun, H.3
  • 26
    • 0028170372 scopus 로고
    • 12 levels and incidence of dementia in a healthy elderly population: A report from the Bronx Longitudinal Aging Study
    • 12 levels and incidence of dementia in a healthy elderly population: a report from the Bronx Longitudinal Aging Study. J Am Geriatr Soc. 1994;42(9):933-936.
    • (1994) J Am Geriatr Soc. , vol.42 , Issue.9 , pp. 933-936
    • Crystal, H.A.1    Ortof, E.2    Frishman, W.H.3
  • 28
    • 16844370424 scopus 로고    scopus 로고
    • Dietary folate and vitamin B-12 intake and cognitive decline among community-dwelling older persons
    • Morris MC, Evans DA, Bienias JL, et al. Dietary folate and vitamin B-12 intake and cognitive decline among community-dwelling older persons. Arch Neurol. 2005;62(4):641-645.
    • (2005) Arch Neurol. , vol.62 , Issue.4 , pp. 641-645
    • Morris, M.C.1    Evans, D.A.2    Bienias, J.L.3
  • 29
    • 36249025250 scopus 로고    scopus 로고
    • Low vitamin B-12 status and risk of cognitive decline in older adults
    • Clarke R, Birks J, Nexo E, et al. Low vitamin B-12 status and risk of cognitive decline in older adults. Am J Clin Nutr. 2007;86(5):1384-1391.
    • (2007) Am J Clin Nutr. , vol.86 , Issue.5 , pp. 1384-1391
    • Clarke, R.1    Birks, J.2    Nexo, E.3
  • 30
    • 27744461645 scopus 로고    scopus 로고
    • Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: The Leiden 85-Plus Study
    • Mooijaart SP, Gussekloo J, Frolich M, et al. Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus Study. Am J Clin Nutr. 2005;82(4):866-871.
    • (2005) Am J Clin Nutr. , vol.82 , Issue.4 , pp. 866-871
    • Mooijaart, S.P.1    Gussekloo, J.2    Frolich, M.3
  • 31
    • 60549117481 scopus 로고    scopus 로고
    • Biochemical indicators of vitamin B(12) and folate insufficiency and cognitive decline
    • Tangney CC, Tang Y, Evans DA, et al. Biochemical indicators of vitamin B(12) and folate insufficiency and cognitive decline. Neurology. 2009;72(4):361-367.
    • (2009) Neurology. , vol.72 , Issue.4 , pp. 361-367
    • Tangney, C.C.1    Tang, Y.2    Evans, D.A.3
  • 32
    • 63649122416 scopus 로고    scopus 로고
    • Vitamin B-12, apolipoprotein e genotype, and cognitive performance in community-living older adults: Evidence of a gene-micronutrient interaction
    • Feng L, Li JL, Yap KB, et al. Vitamin B-12, apolipoprotein E genotype, and cognitive performance in community-living older adults: evidence of a gene-micronutrient interaction. Am J Clin Nutr. 2009;89(4):1263-1268.
    • (2009) Am J Clin Nutr. , vol.89 , Issue.4 , pp. 1263-1268
    • Feng, L.1    Li, J.L.2    Yap, K.B.3
  • 33
    • 27244455440 scopus 로고    scopus 로고
    • High homocysteine and low B vitamins predict cognitive decline in aging men: The Veterans Affairs Normative Aging Study
    • Tucker KL, Qiao N, Scott T, et al. High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study. Am J Clin Nutr. 2005;82(3):627-635.
    • (2005) Am J Clin Nutr. , vol.82 , Issue.3 , pp. 627-635
    • Tucker, K.L.1    Qiao, N.2    Scott, T.3
  • 34
    • 13444260835 scopus 로고    scopus 로고
    • 12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging
    • 12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging. Am J Med. 2005;118(2):161-167.
    • (2005) Am J Med. , vol.118 , Issue.2 , pp. 161-167
    • Kado, D.M.1    Karlamangla, A.S.2    Huang, M.H.3
  • 37
    • 42049114615 scopus 로고    scopus 로고
    • Folate, vitamin B(12), and homocysteine as risk factors for cognitive decline in the elderly
    • Kim JM, Kim SW, Shin IS, et al. Folate, vitamin B(12), and homocysteine as risk factors for cognitive decline in the elderly. Psychiatry Investig. 2008;5(1):36-40.
    • (2008) Psychiatry Investig. , vol.5 , Issue.1 , pp. 36-40
    • Kim, J.M.1    Kim, S.W.2    Shin, I.S.3
  • 38
    • 0031028267 scopus 로고    scopus 로고
    • Nutritional status and cognitive functioning in a normally aging sample: A 6-y reassessment
    • La Rue A, Koehler KM, Wayne SJ, et al. Nutritional status and cognitive functioning in a normally aging sample: a 6-y reassessment. Am J Clin Nutr. 1997;65(1):20-29.
    • (1997) Am J Clin Nutr. , vol.65 , Issue.1 , pp. 20-29
    • La Rue, A.1    Koehler, K.M.2    Wayne, S.J.3
  • 39
    • 28544447509 scopus 로고    scopus 로고
    • Plasma total homocysteine and memory in the elderly: The Hordaland Homocysteine Study
    • Nurk E, Refsum H, Tell GS, et al. Plasma total homocysteine and memory in the elderly: the Hordaland Homocysteine Study. Ann Neurol. 2005;58(6):847-857.
    • (2005) Ann Neurol. , vol.58 , Issue.6 , pp. 847-857
    • Nurk, E.1    Refsum, H.2    Tell, G.S.3
  • 40
    • 0022992740 scopus 로고
    • Meta-analysis in clinical trials
    • DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177-188.
    • (1986) Control Clin Trials. , vol.7 , Issue.3 , pp. 177-188
    • Dersimonian, R.1    Laird, N.2
  • 41
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21(11):1539-1558.
    • (2002) Stat Med. , vol.21 , Issue.11 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 42
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task-Force on Alzheimer's disease
    • McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task-Force on Alzheimer's disease. Neurology. 1984;34(7):939-944.
    • (1984) Neurology. , vol.34 , Issue.7 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 43
    • 0024812158 scopus 로고
    • A study of the reliability of the family history method in genetic studies of Alzheimer disease
    • Silverman JM, Keefe RS, Mohs RC, et al. A study of the reliability of the family history method in genetic studies of Alzheimer disease. Alzheimer Dis Assoc Disord. 1989; 3(4):218-223.
    • (1989) Alzheimer Dis Assoc Disord. , vol.3 , Issue.4 , pp. 218-223
    • Silverman, J.M.1    Keefe, R.S.2    Mohs, R.C.3
  • 45
    • 33748427825 scopus 로고    scopus 로고
    • Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: A randomized, placebo-controlled trial
    • Eussen SJ, de Groot LC, Joosten LW, et al. Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: a randomized, placebo-controlled trial. Am J Clin Nutr. 2006;84(2): 361-370.
    • (2006) Am J Clin Nutr. , vol.84 , Issue.2 , pp. 361-370
    • Eussen, S.J.1    De Groot, L.C.2    Joosten, L.W.3
  • 46
    • 84874505394 scopus 로고
    • American Psychiatric Association 3rd rev ed. Washington, DC: American Psychiatric Association
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 3rd rev ed. Washington, DC: American Psychiatric Association; 1987.
    • (1987) Diagnostic and Statistical Manual of Mental Disorders
  • 47
    • 84870465485 scopus 로고
    • American Psychiatric Association 4th ed. Washington, DC: American Psychiatric Association;
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Association; 1994.
    • (1994) Diagnostic and Statistical Manual of Mental Disorders
  • 49
    • 0026701491 scopus 로고
    • Clinical diagnosis of Alzheimer's disease and other dementias in a population survey. Agreement and causes of disagreement in applying Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition, criteria
    • Fratiglioni L, Grut M, Forsell Y, et al. Clinical diagnosis of Alzheimer's disease and other dementias in a population survey. Agreement and causes of disagreement in applying Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition, criteria. Arch Neurol. 1992; 49(9):927-932.
    • (1992) Arch Neurol. , vol.49 , Issue.9 , pp. 927-932
    • Fratiglioni, L.1    Grut, M.2    Forsell, Y.3
  • 50
    • 66749189122 scopus 로고    scopus 로고
    • Homocysteine and holo-transcobalamin and the risk of dementia and Alzheimers disease: A prospective study
    • Kivipelto M, Annerbo S, Hultdin J, et al. Homocysteine and holo-transcobalamin and the risk of dementia and Alzheimers disease: a prospective study. Eur J Neurol. 2009;16(7):808-813.
    • (2009) Eur J Neurol. , vol.16 , Issue.7 , pp. 808-813
    • Kivipelto, M.1    Annerbo, S.2    Hultdin, J.3
  • 51
    • 78049519410 scopus 로고    scopus 로고
    • Homocysteine and holotranscobalamin and the risk of Alzheimer disease: A longitudinal study
    • Hooshmand B, Solomon A, Kareholt I, et al. Homocysteine and holotranscobalamin and the risk of Alzheimer disease: a longitudinal study. Neurology. 2010;75(16):1408-1414.
    • (2010) Neurology. , vol.75 , Issue.16 , pp. 1408-1414
    • Hooshmand, B.1    Solomon, A.2    Kareholt, I.3
  • 52
    • 59649103167 scopus 로고    scopus 로고
    • Vitamin B-12 and cognition in the elderly
    • Smith AD, Refsum H. Vitamin B-12 and cognition in the elderly. Am J Clin Nutr. 2009;89(2):707S-711S.
    • (2009) Am J Clin Nutr. , vol.89 , Issue.2
    • Smith, A.D.1    Refsum, H.2
  • 53
    • 34547203954 scopus 로고    scopus 로고
    • Clinical aspects of cobalamin deficiency in elderly patients. Epidemiology, causes, clinical manifestations, and treatment with special focus on oral cobalamin therapy
    • Andres E, Vidal-Alaball J, Federici L, et al. Clinical aspects of cobalamin deficiency in elderly patients. Epidemiology, causes, clinical manifestations, and treatment with special focus on oral cobalamin therapy. Eur J Intern Med. 2007; 18(6):456-462.
    • (2007) Eur J Intern Med. , vol.18 , Issue.6 , pp. 456-462
    • Andres, E.1    Vidal-Alaball, J.2    Federici, L.3
  • 54
    • 59649120034 scopus 로고    scopus 로고
    • How common is vitamin B-12 deficiency?
    • Allen LH. How common is vitamin B-12 deficiency? Am J Clin Nutr. 2009;89(2):693S-696S.
    • (2009) Am J Clin Nutr. , vol.89 , Issue.2
    • Allen, L.H.1
  • 55
    • 0041417599 scopus 로고    scopus 로고
    • Plasma vitamin B-12 concentrations in an elderly Latino population are predicted by serum gastrin concentrations and crystalline vitamin B-12 intake
    • Campbell AK, Miller JW, Green R, et al. Plasma vitamin B-12 concentrations in an elderly Latino population are predicted by serum gastrin concentrations and crystalline vitamin B-12 intake. J Nutr. 2003;133(9):2770- 2776.
    • (2003) J Nutr. , vol.133 , Issue.9 , pp. 2770-2776
    • Campbell, A.K.1    Miller, J.W.2    Green, R.3
  • 58
    • 84855924761 scopus 로고    scopus 로고
    • Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: A longitudinal study
    • Hooshmand B, Solomon A, Kareholt I, et al. Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study. J Intern Med. 2012;271(2):204-212.
    • (2012) J Intern Med. , vol.271 , Issue.2 , pp. 204-212
    • Hooshmand, B.1    Solomon, A.2    Kareholt, I.3
  • 59
    • 33745359474 scopus 로고    scopus 로고
    • 12 concentrations in older people: The Banbury B12 Study
    • 12 concentrations in older people: the Banbury B12 Study. Age Ageing. 2006;35(4):416-422.
    • (2006) Age Ageing. , vol.35 , Issue.4 , pp. 416-422
    • Hin, H.1    Clarke, R.2    Sherliker, P.3
  • 60
    • 33845496742 scopus 로고    scopus 로고
    • Methylmalonic acid and cognitive function in the Medical Research Council Cognitive Function and Ageing Study
    • McCracken C, Hudson P, Ellis R, et al. Methylmalonic acid and cognitive function in the Medical Research Council Cognitive Function and Ageing Study. Am J Clin Nutr. 2006;84(6):1406-1411.
    • (2006) Am J Clin Nutr. , vol.84 , Issue.6 , pp. 1406-1411
    • McCracken, C.1    Hudson, P.2    Ellis, R.3
  • 61
    • 12144286057 scopus 로고    scopus 로고
    • Transcobalamin polymorphism and serum holo-transcobalamin in relation to Alzheimer's disease
    • McCaddon A, Blennow K, Hudson P, et al. Transcobalamin polymorphism and serum holo-transcobalamin in relation to Alzheimer's disease. Dement Geriatr Cogn Disord. 2004; 17(3):215-221.
    • (2004) Dement Geriatr Cogn Disord. , vol.17 , Issue.3 , pp. 215-221
    • McCaddon, A.1    Blennow, K.2    Hudson, P.3
  • 62
    • 0038480240 scopus 로고    scopus 로고
    • Low vitamin B-12 status in confirmed Alzheimer's disease as revealed by serum holotranscobala-min
    • Refsum H, Smith AD. Low vitamin B-12 status in confirmed Alzheimer's disease as revealed by serum holotranscobala-min. J Neurol Neurosurg Psychiatry. 2003;74(7):959-961.
    • (2003) J Neurol Neurosurg Psychiatry. , vol.74 , Issue.7 , pp. 959-961
    • Refsum, H.1    Smith, A.D.2
  • 63
    • 0027245667 scopus 로고
    • Serum cobalamin and methylmalonic acid in Alzheimer dementia
    • Kristensen MO, Gulmann NC, Christensen JE, et al. Serum cobalamin and methylmalonic acid in Alzheimer dementia. Acta Neurol Scand. 1993;87(6):475-481.
    • (1993) Acta Neurol Scand. , vol.87 , Issue.6 , pp. 475-481
    • Kristensen, M.O.1    Gulmann, N.C.2    Christensen, J.E.3
  • 64
    • 4344641699 scopus 로고    scopus 로고
    • No effect of vitamin B-12 treatment on cognitive function and depression: A randomized placebo controlled study
    • Hvas AM, Juul S, Lauritzen L, et al. No effect of vitamin B-12 treatment on cognitive function and depression: a randomized placebo controlled study. J Affect Disord. 2004;81(3):269-273.
    • (2004) J Affect Disord. , vol.81 , Issue.3 , pp. 269-273
    • Hvas, A.M.1    Juul, S.2    Lauritzen, L.3
  • 66
    • 0031662856 scopus 로고    scopus 로고
    • Randomized trial of the effect of supplementation on the cognitive function of older people with subnormal cobalamin levels
    • Kwok T, Tang C, Woo J, et al. Randomized trial of the effect of supplementation on the cognitive function of older people with subnormal cobalamin levels. Int J Geriatr Psychiatry. 1998;13(9):611-616.
    • (1998) Int J Geriatr Psychiatry. , vol.13 , Issue.9 , pp. 611-616
    • Kwok, T.1    Tang, C.2    Woo, J.3
  • 67
    • 0038009864 scopus 로고    scopus 로고
    • Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia
    • Clarke R, Harrison G, Richards S, et al. Effect of vitamins and aspirin on markers of platelet activation, oxidative stress and homocysteine in people at high risk of dementia. J Intern Med. 2003;254(1):67-75.
    • (2003) J Intern Med. , vol.254 , Issue.1 , pp. 67-75
    • Clarke, R.1    Harrison, G.2    Richards, S.3
  • 68
    • 78149240857 scopus 로고    scopus 로고
    • Vitamins B(12), B(6), and folic acid for cognition in older men
    • Ford AH, Flicker L, Alfonso H, et al. Vitamins B(12), B(6), and folic acid for cognition in older men. Neurology. 2010; 75(17):1540-1547.
    • (2010) Neurology. , vol.75 , Issue.17 , pp. 1540-1547
    • Ford, A.H.1    Flicker, L.2    Alfonso, H.3
  • 69
    • 20544445241 scopus 로고    scopus 로고
    • Significant correlations of plasma homocysteine and serum methylmalonic acid with movement and cognitive performance in elderly subjects but no improvement from short-term vitamin therapy: A placebo-controlled randomized study
    • Lewerin C, Matousek M, Steen G, et al. Significant correlations of plasma homocysteine and serum methylmalonic acid with movement and cognitive performance in elderly subjects but no improvement from short-term vitamin therapy: a placebo-controlled randomized study. Am J Clin Nutr. 2005;81(5):1155-1162.
    • (2005) Am J Clin Nutr. , vol.81 , Issue.5 , pp. 1155-1162
    • Lewerin, C.1    Matousek, M.2    Steen, G.3
  • 70
    • 33644693101 scopus 로고    scopus 로고
    • Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease
    • Stott DJ, MacIntosh G, Lowe GDO, et al. Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease. Am J Clin Nutr. 2005;82(6):1320-1326.
    • (2005) Am J Clin Nutr. , vol.82 , Issue.6 , pp. 1320-1326
    • Stott, D.J.1    MacIntosh, G.2    Lowe, G.D.O.3
  • 71
    • 84859889194 scopus 로고    scopus 로고
    • Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: A randomized controlled trial
    • de Jager CA, Oulhaj A, Jacoby R, et al. Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial. Int J Geriatr Psychiatry. 2012;27(6):592-560.
    • (2012) Int J Geriatr Psychiatry. , vol.27 , Issue.6 , pp. 592-560
    • De Jager, C.A.1    Oulhaj, A.2    Jacoby, R.3
  • 72
    • 33745652285 scopus 로고    scopus 로고
    • A controlled trial of homocysteine lowering and cognitive performance
    • McMahon JA, Green TJ, Skeaff CM, et al. A controlled trial of homocysteine lowering and cognitive performance. N Engl J Med. 2006;354(26):2764-2772.
    • (2006) N Engl J Med. , vol.354 , Issue.26 , pp. 2764-2772
    • McMahon, J.A.1    Green, T.J.2    Skeaff, C.M.3
  • 73
    • 54049106963 scopus 로고    scopus 로고
    • High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: A randomized controlled trial
    • Aisen PS, Schneider LS, Sano M, et al. High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial. JAMA. 2008;300(15):1774-1783.
    • (2008) JAMA , vol.300 , Issue.15 , pp. 1774-1783
    • Aisen, P.S.1    Schneider, L.S.2    Sano, M.3
  • 74
    • 79957547981 scopus 로고    scopus 로고
    • A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people
    • Kwok T, Lee J, Law CB, et al. A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people. Clin Nutr. 2011;30(3):297-302.
    • (2011) Clin Nutr. , vol.30 , Issue.3 , pp. 297-302
    • Kwok, T.1    Lee, J.2    Law, C.B.3
  • 75
    • 78751613397 scopus 로고    scopus 로고
    • Report of the task force on designing clinical trials in early (predementia) AD
    • Aisen PS, Andrieu S, Sampaio C, et al. Report of the task force on designing clinical trials in early (predementia) AD. Neurology. 2011;76(3):280-286.
    • (2011) Neurology. , vol.76 , Issue.3 , pp. 280-286
    • Aisen, P.S.1    Andrieu, S.2    Sampaio, C.3
  • 76
    • 77958491286 scopus 로고    scopus 로고
    • Summary and discussion: Methodologies to assess long-term effects of nutrition on brain function
    • de Jager CA, Kovatcheva A. Summary and discussion: methodologies to assess long-term effects of nutrition on brain function. Nutr Rev. 2010;68(suppl 1):S53-S58.
    • (2010) Nutr Rev. , vol.68 , Issue.SUPPL. 1
    • De Jager, C.A.1    Kovatcheva, A.2
  • 77
    • 77958458712 scopus 로고    scopus 로고
    • 12 and cognition
    • 12 and cognition. Nutr Rev. 2010;68(suppl 1):S11-S15.
    • (2010) Nutr Rev. , vol.68 , Issue.SUPPL. 1
    • McCracken, C.1
  • 78
    • 41949119170 scopus 로고    scopus 로고
    • Endpoints for trials in Alzheimer's disease: A European task force consensus
    • Vellas B, Andrieu S, Sampaio C, et al. Endpoints for trials in Alzheimer's disease: a European task force consensus. Lancet Neurology. 2008;7(5):436-450.
    • (2008) Lancet Neurology. , vol.7 , Issue.5 , pp. 436-450
    • Vellas, B.1    Andrieu, S.2    Sampaio, C.3
  • 79
    • 33845346815 scopus 로고    scopus 로고
    • Disease-modifying trials in Alzheimer's disease: A European task force consensus
    • Vellas B, Andrieu S, Sampaio C, et al. Disease-modifying trials in Alzheimer's disease: a European task force consensus. Lancet Neurology. 2007;6(1):56-62.
    • (2007) Lancet Neurology. , vol.6 , Issue.1 , pp. 56-62
    • Vellas, B.1    Andrieu, S.2    Sampaio, C.3
  • 80
    • 43249084924 scopus 로고    scopus 로고
    • Magnetic resonance imaging characterization of brain structure and function in mild cognitive impairment: A review
    • Ries ML, Carlsson CM, Rowley HA, et al. Magnetic resonance imaging characterization of brain structure and function in mild cognitive impairment: a review. J Am Geriatr Soc. 2008;56(5):920-934.
    • (2008) J Am Geriatr Soc. , vol.56 , Issue.5 , pp. 920-934
    • Ries, M.L.1    Carlsson, C.M.2    Rowley, H.A.3
  • 81
    • 0037996766 scopus 로고    scopus 로고
    • Longitudinal magnetic resonance imaging studies of older adults: A shrinking brain
    • Resnick SM, Pham DL, Kraut MA, et al. Longitudinal magnetic resonance imaging studies of older adults: a shrinking brain. J Neurosci. 2003;23(8):3295-3301.
    • (2003) J Neurosci. , vol.23 , Issue.8 , pp. 3295-3301
    • Resnick, S.M.1    Pham, D.L.2    Kraut, M.A.3
  • 82
    • 53049084486 scopus 로고    scopus 로고
    • 12 status and rate of brain volume loss in community-dwelling elderly
    • 12 status and rate of brain volume loss in community-dwelling elderly. Neurology. 2008;71(11):826-832.
    • (2008) Neurology. , vol.71 , Issue.11 , pp. 826-832
    • Vogiatzoglou, A.1    Refsum, H.2    Johnston, C.3
  • 83
    • 80055055036 scopus 로고    scopus 로고
    • 12, cognition, and brain MRI measures: A cross-sectional examination
    • 12, cognition, and brain MRI measures: a cross-sectional examination. Neurology. 2011;77(13):1276-1282.
    • (2011) Neurology. , vol.77 , Issue.13 , pp. 1276-1282
    • Tangney, C.C.1    Aggarwal, N.T.2    Li, H.3
  • 84
    • 77958567930 scopus 로고    scopus 로고
    • Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: A randomized controlled trial
    • doi:10.1371/journal.pone.0012244
    • Smith AD, Smith SM, de Jager CA, et al. Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial. Plos One. 2010;5(9):e12244. (doi:10.1371/journal.pone.0012244).
    • (2010) Plos One. , vol.5 , Issue.9
    • Smith, A.D.1    Smith, S.M.2    De Jager, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.