Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: A randomized, placebo-controlled trial

American Journal of Clinical Nutrition

Volumn 84, Issue 2, 2006, Pages 361-370

  Eussen, Simone J ^a   De Groot, Lisette C ^a   Joosten, Liesbeth W ^b   Bloo, Rubia J ^b   Clarke, Robert ^c   Ueland, Per M ^d   Schneede, Jörn ^d,e   Blom, Henk J ^b   Hoefnagels, Willibrord H ^b   Van Staveren, Wija A ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF BERGEN   (Norway)

^e UMEÅ UNIVERSITY   (Sweden)

Author keywords

Cognitive function; Elderly; Oral supplementation; Vitamin B 12 deficiency

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; METHYLMALONIC ACID; PLACEBO; TRANSCOBALAMIN;

AGED; AMINO ACID BLOOD LEVEL; ARTICLE; ATTENTION; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYANOCOBALAMIN DEFICIENCY; DIETARY INTAKE; DISEASE SEVERITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; FEMALE; FOLIC ACID BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; MEMORY; NEUROPSYCHOLOGICAL TEST; NUTRITIONAL ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; SENSORIMOTOR FUNCTION; TREATMENT OUTCOME; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION; BLOOD; COGNITIVE DEFECT; DIET SUPPLEMENTATION; DRUG COMBINATION; DRUG EFFECT; METABOLISM; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; PSYCHOMOTOR PERFORMANCE;

ADMINISTRATION, ORAL; AGED; AGED, 80 AND OVER; COGNITION; COGNITION DISORDERS; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; FOLIC ACID; HOMOCYSTEINE; HUMANS; MALE; MEMORY; METHYLMALONIC ACID; PSYCHOMOTOR PERFORMANCE; TRANSCOBALAMINS; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

EID: 33748427825     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/84.2.361     Document Type: Article

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