Analysing molecular polar surface descriptors to predict blood-brain barrier permeation

International Journal of Computational Biology and Drug Design

Volumn 6, Issue 1-2, 2013, Pages 146-156

  Shityakov, Sergey ^a   Neuhaus, Winfried ^a,b   Dandekar, Thomas ^a   Förster, Carola ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Blood brain barrier; LogBB; P glycoprotein; Polar surface descriptors

Indexed keywords

AMITRIPTYLINE; CARBAMAZEPINE; CARBAMAZEPINE 10,11 OXIDE; CIMETIDINE; CLONIDINE; DESIPRAMINE; DOMPERIDONE; ICOTIDINE; IMIPRAMINE; LUPITIDINE; MEPYRAMINE; MIANSERIN; MIRTAZAPINE; PALIPERIDONE; RANITIDINE; RISPERIDONE; TEMELASTINE; TIBOLONE; ZOLANTIDINE;

ARTICLE; BLOOD BRAIN BARRIER; HUMAN; IN VIVO STUDY; MEMBRANE PERMEABILITY; MOLECULE; POLAR SURFACE; STEADY STATE; SURFACE PROPERTY;

EID: 84874435862     PISSN: 17560756     EISSN: 17560764     Source Type: Journal    
DOI: 10.1504/IJCBDD.2013.052195     Document Type: Article

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