Senescence evasion in melanoma progression: Uncoupling of DNA-damage signaling from p53 activation and p21 expression

Pigment Cell and Melanoma Research

Volumn 26, Issue 2, 2013, Pages 226-235

  Mackenzie Ross, Alastair D ^a,c   Cook, Martin G ^b   Chong, Heung ^a   Hossain, Mehnaz ^a   Pandha, Hardev S ^b   Bennett, Dorothy C ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF SURREY   (United Kingdom)

^c ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Diagnosis; DNA damage signaling; Melanoma progression; Nevus; P16; P53; Senescence

Indexed keywords

CHECKPOINT KINASE 2; PROTEIN P21; PROTEIN P53;

ARTICLE; CANCER GROWTH; CONTROLLED STUDY; DNA DAMAGE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MELANOMA; NEVUS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENESCENCE; UPREGULATION;

CELL AGING; CELL NUCLEUS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DISEASE PROGRESSION; DNA DAMAGE; HUMANS; MELANOMA; PHOSPHOPROTEINS; PHOSPHORYLATION; PIGMENTATION; PROTEIN-SERINE-THREONINE KINASES; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84874391653     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/pcmr.12060     Document Type: Article

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