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Volumn 20, Issue 2, 2013, Pages 262-271

A chemical biology strategy to analyze rheostat-like protein kinase-dependent regulation

Author keywords

[No Author keywords available]

Indexed keywords

AURORA KINASE INHIBITOR; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; RHEOSTAT; UNCLASSIFIED DRUG;

EID: 84874316301     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2013.01.003     Document Type: Article
Times cited : (16)

References (49)
  • 1
    • 61649114657 scopus 로고    scopus 로고
    • Kinase-targeted libraries: The design and synthesis of novel, potent, and selective kinase inhibitors
    • I. Akritopoulou-Zanze, and P.J. Hajduk Kinase-targeted libraries: the design and synthesis of novel, potent, and selective kinase inhibitors Drug Discov. Today 14 2009 291 297
    • (2009) Drug Discov. Today , vol.14 , pp. 291-297
    • Akritopoulou-Zanze, I.1    Hajduk, P.J.2
  • 2
    • 36248984986 scopus 로고    scopus 로고
    • Schizosaccharomyces pombe protein phosphatase 1 in mitosis, endocytosis and a partnership with Wsh3/Tea4 to control polarised growth
    • I. Alvarez-Tabarés, A. Grallert, J.M. Ortiz, and I.M. Hagan Schizosaccharomyces pombe protein phosphatase 1 in mitosis, endocytosis and a partnership with Wsh3/Tea4 to control polarised growth J. Cell Sci. 120 2007 3589 3601
    • (2007) J. Cell Sci. , vol.120 , pp. 3589-3601
    • Alvarez-Tabarés, I.1    Grallert, A.2    Ortiz, J.M.3    Hagan, I.M.4
  • 3
    • 3142781225 scopus 로고    scopus 로고
    • Small-molecule inhibitors of protein-protein interactions: Progressing towards the dream
    • M.R. Arkin, and J.A. Wells Small-molecule inhibitors of protein-protein interactions: progressing towards the dream Nat. Rev. Drug Discov. 3 2004 301 317
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 301-317
    • Arkin, M.R.1    Wells, J.A.2
  • 5
    • 80052163881 scopus 로고    scopus 로고
    • A general framework for inhibitor resistance in protein kinases
    • D. Balzano, S. Santaguida, A. Musacchio, and F. Villa A general framework for inhibitor resistance in protein kinases Chem. Biol. 18 2011 966 975
    • (2011) Chem. Biol. , vol.18 , pp. 966-975
    • Balzano, D.1    Santaguida, S.2    Musacchio, A.3    Villa, F.4
  • 7
    • 70349333819 scopus 로고    scopus 로고
    • Mitotic phosphatases: From entry guards to exit guides
    • M. Bollen, D.W. Gerlich, and B. Lesage Mitotic phosphatases: from entry guards to exit guides Trends Cell Biol. 19 2009 531 541
    • (2009) Trends Cell Biol. , vol.19 , pp. 531-541
    • Bollen, M.1    Gerlich, D.W.2    Lesage, B.3
  • 8
    • 34247578600 scopus 로고    scopus 로고
    • Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells
    • M.E. Burkard, C.L. Randall, S. Larochelle, C. Zhang, K.M. Shokat, R.P. Fisher, and P.V. Jallepalli Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells Proc. Natl. Acad. Sci. USA 104 2007 4383 4388
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 4383-4388
    • Burkard, M.E.1    Randall, C.L.2    Larochelle, S.3    Zhang, C.4    Shokat, K.M.5    Fisher, R.P.6    Jallepalli, P.V.7
  • 9
    • 51949111451 scopus 로고    scopus 로고
    • Chemical probes for histone-modifying enzymes
    • P.A. Cole Chemical probes for histone-modifying enzymes Nat. Chem. Biol. 4 2008 590 597
    • (2008) Nat. Chem. Biol. , vol.4 , pp. 590-597
    • Cole, P.A.1
  • 10
    • 78650842310 scopus 로고    scopus 로고
    • Driving the cell cycle with a minimal CDK control network
    • D. Coudreuse, and P. Nurse Driving the cell cycle with a minimal CDK control network Nature 468 2010 1074 1079
    • (2010) Nature , vol.468 , pp. 1074-1079
    • Coudreuse, D.1    Nurse, P.2
  • 11
    • 42549095588 scopus 로고    scopus 로고
    • Chemical genetic analysis of the regulatory role of Cdc2p in the S. pombe septation initiation network
    • S. Dischinger, A. Krapp, L. Xie, J.R. Paulson, and V. Simanis Chemical genetic analysis of the regulatory role of Cdc2p in the S. pombe septation initiation network J. Cell Sci. 121 2008 843 853
    • (2008) J. Cell Sci. , vol.121 , pp. 843-853
    • Dischinger, S.1    Krapp, A.2    Xie, L.3    Paulson, J.R.4    Simanis, V.5
  • 13
    • 0029843496 scopus 로고    scopus 로고
    • Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes
    • H. Funabiki, K. Kumada, and M. Yanagida Fission yeast Cut1 and Cut2 are essential for sister chromatid separation, concentrate along the metaphase spindle and form large complexes EMBO J. 15 1996 6617 6628
    • (1996) EMBO J. , vol.15 , pp. 6617-6628
    • Funabiki, H.1    Kumada, K.2    Yanagida, M.3
  • 15
    • 35648947463 scopus 로고    scopus 로고
    • Aurora controls sister kinetochore mono-orientation and homolog bi-orientation in meiosis-I
    • S. Hauf, A. Biswas, M. Langegger, S.A. Kawashima, T. Tsukahara, and Y. Watanabe Aurora controls sister kinetochore mono-orientation and homolog bi-orientation in meiosis-I EMBO J. 26 2007 4475 4486
    • (2007) EMBO J. , vol.26 , pp. 4475-4486
    • Hauf, S.1    Biswas, A.2    Langegger, M.3    Kawashima, S.A.4    Tsukahara, T.5    Watanabe, Y.6
  • 16
    • 0001503931 scopus 로고
    • Isolation and characterization of Schizosaccharomyces pombe cutmutants that block nuclear division but not cytokinesis
    • T. Hirano, S. Funahashi, T. Uemura, and M. Yanagida Isolation and characterization of Schizosaccharomyces pombe cutmutants that block nuclear division but not cytokinesis EMBO J. 5 1986 2973 2979
    • (1986) EMBO J. , vol.5 , pp. 2973-2979
    • Hirano, T.1    Funahashi, S.2    Uemura, T.3    Yanagida, M.4
  • 18
    • 84864402419 scopus 로고    scopus 로고
    • Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology
    • S.A. Kawashima, A. Takemoto, P. Nurse, and T.M. Kapoor Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology Chem. Biol. 19 2012 893 901
    • (2012) Chem. Biol. , vol.19 , pp. 893-901
    • Kawashima, S.A.1    Takemoto, A.2    Nurse, P.3    Kapoor, T.M.4
  • 19
    • 77149157497 scopus 로고    scopus 로고
    • Strategies for the identification of kinase substrates using analog-sensitive kinases
    • A. Koch, and S. Hauf Strategies for the identification of kinase substrates using analog-sensitive kinases Eur. J. Cell Biol. 89 2010 184 193
    • (2010) Eur. J. Cell Biol. , vol.89 , pp. 184-193
    • Koch, A.1    Hauf, S.2
  • 21
    • 84871161766 scopus 로고    scopus 로고
    • High mitotic activity of Polo-like Kinase 1 is required for chromosome segregation and genomic integrity in human epithelial cells
    • R.F. Lera, and M.E. Burkard High mitotic activity of Polo-like Kinase 1 is required for chromosome segregation and genomic integrity in human epithelial cells J. Biol. Chem. 287 2012 42812 42825
    • (2012) J. Biol. Chem. , vol.287 , pp. 42812-42825
    • Lera, R.F.1    Burkard, M.E.2
  • 22
    • 77949762923 scopus 로고    scopus 로고
    • Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase
    • D. Liu, M. Vleugel, C.B. Backer, T. Hori, T. Fukagawa, I.M. Cheeseman, and M.A. Lampson Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase J. Cell Biol. 188 2010 809 820
    • (2010) J. Cell Biol. , vol.188 , pp. 809-820
    • Liu, D.1    Vleugel, M.2    Backer, C.B.3    Hori, T.4    Fukagawa, T.5    Cheeseman, I.M.6    Lampson, M.A.7
  • 24
    • 79960990847 scopus 로고    scopus 로고
    • Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I)
    • X. Morelli, R. Bourgeas, and P. Roche Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I) Curr. Opin. Chem. Biol. 15 2011 475 481
    • (2011) Curr. Opin. Chem. Biol. , vol.15 , pp. 475-481
    • Morelli, X.1    Bourgeas, R.2    Roche, P.3
  • 25
    • 0026025891 scopus 로고
    • Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
    • S. Moreno, A. Klar, and P. Nurse Molecular genetic analysis of fission yeast Schizosaccharomyces pombe Methods Enzymol. 194 1991 795 823
    • (1991) Methods Enzymol. , vol.194 , pp. 795-823
    • Moreno, S.1    Klar, A.2    Nurse, P.3
  • 27
    • 79958119414 scopus 로고    scopus 로고
    • Condensin phosphorylated by the Aurora-B-like kinase Ark1 is continuously required until telophase in a mode distinct from Top2
    • N. Nakazawa, R. Mehrotra, M. Ebe, and M. Yanagida Condensin phosphorylated by the Aurora-B-like kinase Ark1 is continuously required until telophase in a mode distinct from Top2 J. Cell Sci. 124 2011 1795 1807
    • (2011) J. Cell Sci. , vol.124 , pp. 1795-1807
    • Nakazawa, N.1    Mehrotra, R.2    Ebe, M.3    Yanagida, M.4
  • 28
    • 34247472032 scopus 로고    scopus 로고
    • Uncovering genetic relationships using small molecules that selectively target yeast cell cycle mutants
    • M.T. Nehil, C.M. Tamble, D.J. Combs, D.R. Kellogg, and R.S. Lokey Uncovering genetic relationships using small molecules that selectively target yeast cell cycle mutants Chem. Biol. Drug Des. 69 2007 258 264
    • (2007) Chem. Biol. Drug Des. , vol.69 , pp. 258-264
    • Nehil, M.T.1    Tamble, C.M.2    Combs, D.J.3    Kellogg, D.R.4    Lokey, R.S.5
  • 29
    • 0029008281 scopus 로고
    • The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells
    • H. Ohkura, I.M. Hagan, and D.M. Glover The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells Genes Dev. 9 1995 1059 1073
    • (1995) Genes Dev. , vol.9 , pp. 1059-1073
    • Ohkura, H.1    Hagan, I.M.2    Glover, D.M.3
  • 30
    • 33750238670 scopus 로고    scopus 로고
    • Probing cell-division phenotype space and Polo-like kinase function using small molecules
    • U. Peters, J. Cherian, J.H. Kim, B.H. Kwok, and T.M. Kapoor Probing cell-division phenotype space and Polo-like kinase function using small molecules Nat. Chem. Biol. 2 2006 618 626
    • (2006) Nat. Chem. Biol. , vol.2 , pp. 618-626
    • Peters, U.1    Cherian, J.2    Kim, J.H.3    Kwok, B.H.4    Kapoor, T.M.5
  • 31
    • 0037380133 scopus 로고    scopus 로고
    • S. pombe aurora kinase/survivin is required for chromosome condensation and the spindle checkpoint attachment response
    • J. Petersen, and I.M. Hagan S. pombe aurora kinase/survivin is required for chromosome condensation and the spindle checkpoint attachment response Curr. Biol. 13 2003 590 597
    • (2003) Curr. Biol. , vol.13 , pp. 590-597
    • Petersen, J.1    Hagan, I.M.2
  • 32
    • 0035694554 scopus 로고    scopus 로고
    • The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation
    • J. Petersen, J. Paris, M. Willer, M. Philippe, and I.M. Hagan The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation J. Cell Sci. 114 2001 4371 4384
    • (2001) J. Cell Sci. , vol.114 , pp. 4371-4384
    • Petersen, J.1    Paris, J.2    Willer, M.3    Philippe, M.4    Hagan, I.M.5
  • 33
    • 65249182240 scopus 로고    scopus 로고
    • Kinetochore geometry defined by cohesion within the centromere
    • T. Sakuno, K. Tada, and Y. Watanabe Kinetochore geometry defined by cohesion within the centromere Nature 458 2009 852 858
    • (2009) Nature , vol.458 , pp. 852-858
    • Sakuno, T.1    Tada, K.2    Watanabe, Y.3
  • 34
    • 0031898645 scopus 로고    scopus 로고
    • New alleles of the yeast MPS1 gene reveal multiple requirements in spindle pole body duplication
    • A.R. Schutz, and M. Winey New alleles of the yeast MPS1 gene reveal multiple requirements in spindle pole body duplication Mol. Biol. Cell 9 1998 759 774
    • (1998) Mol. Biol. Cell , vol.9 , pp. 759-774
    • Schutz, A.R.1    Winey, M.2
  • 35
    • 67650061988 scopus 로고    scopus 로고
    • Discovery and exploitation of inhibitor-resistant aurora and polo kinase mutants for the analysis of mitotic networks
    • P.J. Scutt, M.L. Chu, D.A. Sloane, M. Cherry, C.R. Bignell, D.H. Williams, and P.A. Eyers Discovery and exploitation of inhibitor-resistant aurora and polo kinase mutants for the analysis of mitotic networks J. Biol. Chem. 284 2009 15880 15893
    • (2009) J. Biol. Chem. , vol.284 , pp. 15880-15893
    • Scutt, P.J.1    Chu, M.L.2    Sloane, D.A.3    Cherry, M.4    Bignell, C.R.5    Williams, D.H.6    Eyers, P.A.7
  • 38
    • 2342494273 scopus 로고    scopus 로고
    • Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase
    • M. Sullivan, T. Higuchi, V.L. Katis, and F. Uhlmann Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase Cell 117 2004 471 482
    • (2004) Cell , vol.117 , pp. 471-482
    • Sullivan, M.1    Higuchi, T.2    Katis, V.L.3    Uhlmann, F.4
  • 39
    • 0033200339 scopus 로고    scopus 로고
    • Fission yeast condensin complex: Essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4
    • T. Sutani, T. Yuasa, T. Tomonaga, N. Dohmae, K. Takio, and M. Yanagida Fission yeast condensin complex: essential roles of non-SMC subunits for condensation and Cdc2 phosphorylation of Cut3/SMC4 Genes Dev. 13 1999 2271 2283
    • (1999) Genes Dev. , vol.13 , pp. 2271-2283
    • Sutani, T.1    Yuasa, T.2    Tomonaga, T.3    Dohmae, N.4    Takio, K.5    Yanagida, M.6
  • 40
    • 79959549133 scopus 로고    scopus 로고
    • Condensin association with histone H2A shapes mitotic chromosomes
    • K. Tada, H. Susumu, T. Sakuno, and Y. Watanabe Condensin association with histone H2A shapes mitotic chromosomes Nature 474 2011 477 483
    • (2011) Nature , vol.474 , pp. 477-483
    • Tada, K.1    Susumu, H.2    Sakuno, T.3    Watanabe, Y.4
  • 41
    • 80053645042 scopus 로고    scopus 로고
    • Examining the dynamics of chromosomal passenger complex (CPC)-dependent phosphorylation during cell division
    • L. Tan, and T.M. Kapoor Examining the dynamics of chromosomal passenger complex (CPC)-dependent phosphorylation during cell division Proc. Natl. Acad. Sci. USA 108 2011 16675 16680
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 16675-16680
    • Tan, L.1    Kapoor, T.M.2
  • 44
    • 67650998480 scopus 로고    scopus 로고
    • A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism
    • V. Vanoosthuyse, and K.G. Hardwick A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism Curr. Biol. 19 2009 1176 1181
    • (2009) Curr. Biol. , vol.19 , pp. 1176-1181
    • Vanoosthuyse, V.1    Hardwick, K.G.2
  • 45
    • 80052621348 scopus 로고    scopus 로고
    • Aurora B dynamics at centromeres create a diffusion-based phosphorylation gradient
    • E. Wang, E.R. Ballister, and M.A. Lampson Aurora B dynamics at centromeres create a diffusion-based phosphorylation gradient J. Cell Biol. 194 2011 539 549
    • (2011) J. Cell Biol. , vol.194 , pp. 539-549
    • Wang, E.1    Ballister, E.R.2    Lampson, M.A.3
  • 46
    • 0036181181 scopus 로고    scopus 로고
    • Fission yeast Rad26 is a regulatory subunit of the Rad3 checkpoint kinase
    • T.D. Wolkow, and T. Enoch Fission yeast Rad26 is a regulatory subunit of the Rad3 checkpoint kinase Mol. Biol. Cell 13 2002 480 492
    • (2002) Mol. Biol. Cell , vol.13 , pp. 480-492
    • Wolkow, T.D.1    Enoch, T.2
  • 47
    • 0024369960 scopus 로고
    • Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies
    • A. Woods, T. Sherwin, R. Sasse, T.H. MacRae, A.J. Baines, and K. Gull Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies J. Cell Sci. 93 1989 491 500
    • (1989) J. Cell Sci. , vol.93 , pp. 491-500
    • Woods, A.1    Sherwin, T.2    Sasse, R.3    MacRae, T.H.4    Baines, A.J.5    Gull, K.6
  • 48
    • 78650043246 scopus 로고    scopus 로고
    • Gradient of increasing Aurora B kinase activity is required for cells to execute mitosis
    • Z. Xu, P. Vagnarelli, H. Ogawa, K. Samejima, and W.C. Earnshaw Gradient of increasing Aurora B kinase activity is required for cells to execute mitosis J. Biol. Chem. 285 2010 40163 40170
    • (2010) J. Biol. Chem. , vol.285 , pp. 40163-40170
    • Xu, Z.1    Vagnarelli, P.2    Ogawa, H.3    Samejima, K.4    Earnshaw, W.C.5


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