A myosin-V inhibitor based on privileged chemical scaffolds

Angewandte Chemie - International Edition

Volumn 49, Issue 45, 2010, Pages 8484-8488

  Islam, Kabirul ^a   Chin, Harvey F ^b   Olivares, Adrian O ^b   Saunders, Lauren P ^b   De la cruz, Enrique M ^b   Kapoor, Tarun M ^a,c  

^a ROCKEFELLER UNIVERSITY   (United States)

^b YALE UNIVERSITY   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Inhibitors; Kinases; Motor proteins; Privileged scaffolds; Structure activity relationships

Indexed keywords

INHIBITORS; KINASES; MOTOR PROTEINS; PRIVILEGED SCAFFOLDS; STRUCTURE ACTIVITY RELATIONSHIPS;

ADENOSINETRIPHOSPHATE; PHOSPHATES; SCAFFOLDS;

PROTEINS;

ENZYME INHIBITOR; INDOLE DERIVATIVE; MYOSIN V; OXINDOLE; PYRAZOLE DERIVATIVE; PYRAZOLOPYRIDINE; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; PYRROLOPYRIMIDINE;

ANIMAL; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; HUMAN; KINETICS; METABOLISM; MOUSE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ENZYME INHIBITORS; HUMANS; INDOLES; KINETICS; MICE; MYOSIN TYPE V; PYRAZOLES; PYRIDINES; PYRIMIDINES; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78149420077     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201004026     Document Type: Article

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