-
1
-
-
55949130712
-
Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats
-
Aubry L, Bugi A, Lefort N, Rousseau F, Peschanski M, Perrier AL,. 2008. Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats. Proc Natl Acad Sci USA 105: 16707-16712.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16707-16712
-
-
Aubry, L.1
Bugi, A.2
Lefort, N.3
Rousseau, F.4
Peschanski, M.5
Perrier, A.L.6
-
2
-
-
0034627143
-
Motor and cognitive improvements in patients with Huntington's disease after neural transplantation
-
Bachoud-Levi AC, Remy P, Nguyen JP, Brugieres P, Lefaucheur JP, Bourdet C, Baudic S, Gaura V, Maison P, Haddad B, Boisse MF, Grandmougin T, Jeny R, Bartolomeo P, Dalla Barba G, Degos JD, Lisovoski F, Ergis AM, Pailhous E, Cesaro P, Hantraye P, Peschanski M,. 2000. Motor and cognitive improvements in patients with Huntington's disease after neural transplantation. Lancet 356: 1975-1979.
-
(2000)
Lancet
, vol.356
, pp. 1975-1979
-
-
Bachoud-Levi, A.C.1
Remy, P.2
Nguyen, J.P.3
Brugieres, P.4
Lefaucheur, J.P.5
Bourdet, C.6
Baudic, S.7
Gaura, V.8
Maison, P.9
Haddad, B.10
Boisse, M.F.11
Grandmougin, T.12
Jeny, R.13
Bartolomeo, P.14
Dalla Barba, G.15
Degos, J.D.16
Lisovoski, F.17
Ergis, A.M.18
Pailhous, E.19
Cesaro, P.20
Hantraye, P.21
Peschanski, M.22
more..
-
3
-
-
33644967927
-
Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: A long-term follow-up study
-
Bachoud-Levi AC, Gaura V, Brugieres P, Lefaucheur JP, Boisse MF, Maison P, Baudic S, Ribeiro MJ, Bourdet C, Remy P, Cesaro P, Hantraye P, Peschanski M,. 2006. Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: A long-term follow-up study. Lancet Neurol 5: 303-309.
-
(2006)
Lancet Neurol
, vol.5
, pp. 303-309
-
-
Bachoud-Levi, A.C.1
Gaura, V.2
Brugieres, P.3
Lefaucheur, J.P.4
Boisse, M.F.5
Maison, P.6
Baudic, S.7
Ribeiro, M.J.8
Bourdet, C.9
Remy, P.10
Cesaro, P.11
Hantraye, P.12
Peschanski, M.13
-
4
-
-
39749179979
-
Stem cell factor and mesenchymal and neural stem cell transplantation in a rat model of Huntington's disease
-
Bantubungi K, Blum D, Cuvelier L, Wislet-Gendebien S, Rogister B, Brouillet E, Schiffmann SN,. 2008. Stem cell factor and mesenchymal and neural stem cell transplantation in a rat model of Huntington's disease. Mol Cell Neurosci 37: 454-470.
-
(2008)
Mol Cell Neurosci
, vol.37
, pp. 454-470
-
-
Bantubungi, K.1
Blum, D.2
Cuvelier, L.3
Wislet-Gendebien, S.4
Rogister, B.5
Brouillet, E.6
Schiffmann, S.N.7
-
6
-
-
0026043565
-
Chronic quinolinic acid lesions in rats closely resemble Huntington's disease
-
Beal MF, Ferrante RJ, Swartz KJ, Kowall NW,. 1991. Chronic quinolinic acid lesions in rats closely resemble Huntington's disease. J Neurosci 11: 1649-1659.
-
(1991)
J Neurosci
, vol.11
, pp. 1649-1659
-
-
Beal, M.F.1
Ferrante, R.J.2
Swartz, K.J.3
Kowall, N.W.4
-
7
-
-
0027433553
-
Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
-
Beal MF, Brouillet E, Jenkins BG, Ferrante RJ, Kowall NW, Miller JM, Storey E, Srivastava R, Rosen BR, Hyman BT,. 1993. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. J Neurosci 13: 4181-4192.
-
(1993)
J Neurosci
, vol.13
, pp. 4181-4192
-
-
Beal, M.F.1
Brouillet, E.2
Jenkins, B.G.3
Ferrante, R.J.4
Kowall, N.W.5
Miller, J.M.6
Storey, E.7
Srivastava, R.8
Rosen, B.R.9
Hyman, B.T.10
-
8
-
-
0035854087
-
Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat
-
Blum D, Gall D, Cuvelier L, Schiffmann SN,. 2001. Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat. Neuroreport 12: 1769-1772.
-
(2001)
Neuroreport
, vol.12
, pp. 1769-1772
-
-
Blum, D.1
Gall, D.2
Cuvelier, L.3
Schiffmann, S.N.4
-
9
-
-
0031400272
-
Hyperactivity and hypoactivity in a rat model of Huntington's disease: The systemic 3-nitropropionic acid model
-
Borlongan CV, Koutouzis TK, Freeman TB, Hauser RA, Cahill DW, Sanberg PR,. 1997. Hyperactivity and hypoactivity in a rat model of Huntington's disease: The systemic 3-nitropropionic acid model. Brain Res Brain Res Protoc 1: 253-257.
-
(1997)
Brain Res Brain Res Protoc
, vol.1
, pp. 253-257
-
-
Borlongan, C.V.1
Koutouzis, T.K.2
Freeman, T.B.3
Hauser, R.A.4
Cahill, D.W.5
Sanberg, P.R.6
-
10
-
-
0029925184
-
Trinucleotide repeat length and clinical progression in Huntington's disease
-
Brandt J, Bylsma FW, Gross R, Stine OC, Ranen N, Ross CA,. 1996. Trinucleotide repeat length and clinical progression in Huntington's disease. Neurology 46: 527-531.
-
(1996)
Neurology
, vol.46
, pp. 527-531
-
-
Brandt, J.1
Bylsma, F.W.2
Gross, R.3
Stine, O.C.4
Ranen, N.5
Ross, C.A.6
-
11
-
-
33749633639
-
Modeling polyglutamine pathogenesis in C. elegans
-
Brignull HR, Morley JF, Garcia SM, Morimoto RI,. 2006. Modeling polyglutamine pathogenesis in C. elegans. Methods Enzymol 412: 256-282.
-
(2006)
Methods Enzymol
, vol.412
, pp. 256-282
-
-
Brignull, H.R.1
Morley, J.F.2
Garcia, S.M.3
Morimoto, R.I.4
-
12
-
-
0029118136
-
Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates
-
Brouillet E, Hantraye P, Ferrante RJ, Dolan R, Leroy-Willig A, Kowall NW, Beal MF,. 1995. Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates. Proc Natl Acad Sci USA 92: 7105-7109.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7105-7109
-
-
Brouillet, E.1
Hantraye, P.2
Ferrante, R.J.3
Dolan, R.4
Leroy-Willig, A.5
Kowall, N.W.6
Beal, M.F.7
-
13
-
-
34047118680
-
Generating neuron-like cells from BM-derived mesenchymal stromal cells in vitro
-
Choong PF, Mok PL, Cheong SK, Leong CF, Then KY,. 2007. Generating neuron-like cells from BM-derived mesenchymal stromal cells in vitro. Cytotherapy 9: 170-183.
-
(2007)
Cytotherapy
, vol.9
, pp. 170-183
-
-
Choong, P.F.1
Mok, P.L.2
Cheong, S.K.3
Leong, C.F.4
Then, K.Y.5
-
14
-
-
0024217658
-
Striatal grafts in the ibotenic acid-lesioned neostriatum: Ultrastructural and immunocytochemical studies
-
Clarke DJ, Dunnett SB, Isacson O, Bjorklund A,. 1988a. Striatal grafts in the ibotenic acid-lesioned neostriatum: Ultrastructural and immunocytochemical studies. Prog Brain Res 78: 47-53.
-
(1988)
Prog Brain Res
, vol.78
, pp. 47-53
-
-
Clarke, D.J.1
Dunnett, S.B.2
Isacson, O.3
Bjorklund, A.4
-
15
-
-
0023945243
-
Striatal grafts in rats with unilateral neostriatal lesions - I. Ultrastructural evidence of afferent synaptic inputs from the host nigrostriatal pathway
-
Clarke DJ, Dunnett SB, Isacson O, Sirinathsinghji DJ, Bjorklund A,. 1988b. Striatal grafts in rats with unilateral neostriatal lesions-I. Ultrastructural evidence of afferent synaptic inputs from the host nigrostriatal pathway. Neuroscience 24: 791-801.
-
(1988)
Neuroscience
, vol.24
, pp. 791-801
-
-
Clarke, D.J.1
Dunnett, S.B.2
Isacson, O.3
Sirinathsinghji, D.J.4
Bjorklund, A.5
-
16
-
-
0023750525
-
Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease
-
de la Monte SM, Vonsattel JP, Richardson EP, Jr., 1988. Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease. J Neuropathol Exp Neurol 47: 516-525.
-
(1988)
J Neuropathol Exp Neurol
, vol.47
, pp. 516-525
-
-
De La Monte, S.M.1
Vonsattel, J.P.2
Richardson Jr., E.P.3
-
17
-
-
77955278434
-
Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease
-
Dey ND, Bombard MC, Roland BP, Davidson S, Lu M, Rossignol J, Sandstrom MI, Skeel RL, Lescaudron L, Dunbar GL,. 2010. Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease. Behav Brain Res 214: 193-200.
-
(2010)
Behav Brain Res
, vol.214
, pp. 193-200
-
-
Dey, N.D.1
Bombard, M.C.2
Roland, B.P.3
Davidson, S.4
Lu, M.5
Rossignol, J.6
Sandstrom, M.I.7
Skeel, R.L.8
Lescaudron, L.9
Dunbar, G.L.10
-
18
-
-
0028989602
-
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
-
DiFiglia M, Sapp E, Chase K, Schwarz C, Meloni A, Young C, Martin E, Vonsattel JP, Carraway R, Reeves SA, Boyce FM, Aronin N,. 1995. Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons. Neuron 14: 1075-1081.
-
(1995)
Neuron
, vol.14
, pp. 1075-1081
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.3
Schwarz, C.4
Meloni, A.5
Young, C.6
Martin, E.7
Vonsattel, J.P.8
Carraway, R.9
Reeves, S.A.10
Boyce, F.M.11
Aronin, N.12
-
19
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DiFiglia M, Sapp E, Chase KO, Davies SW, Bates GP, Vonsattel JP, Aronin N,. 1997. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277: 1990-1993.
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
20
-
-
77955922748
-
Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease
-
Dowie MJ, Bradshaw HB, Howard ML, Nicholson LF, Faull RL, Hannan AJ, Glass M,. 2010. Altered CB1 receptor and endocannabinoid levels precede motor symptom onset in a transgenic mouse model of Huntington's disease. Neuroscience 170: 324-336.
-
(2010)
Neuroscience
, vol.170
, pp. 324-336
-
-
Dowie, M.J.1
Bradshaw, H.B.2
Howard, M.L.3
Nicholson, L.F.4
Faull, R.L.5
Hannan, A.J.6
Glass, M.7
-
21
-
-
0033757718
-
Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice
-
Dragatsis I, Levine MS, Zeitlin S,. 2000. Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice. Nat Genet 26: 300-306.
-
(2000)
Nat Genet
, vol.26
, pp. 300-306
-
-
Dragatsis, I.1
Levine, M.S.2
Zeitlin, S.3
-
22
-
-
33847673272
-
Cell transplantation for Huntington's disease Should we continue
-
Dunnett SB, Rosser AE,. 2007. Cell transplantation for Huntington's disease Should we continue ? Brain Res Bull 72: 132-147.
-
(2007)
Brain Res Bull
, vol.72
, pp. 132-147
-
-
Dunnett, S.B.1
Rosser, A.E.2
-
23
-
-
0023919424
-
Striatal grafts in rats with unilateral neostriatal lesions - III. Recovery from dopamine-dependent motor asymmetry and deficits in skilled paw reaching
-
Dunnett SB, Isacson O, Sirinathsinghji DJ, Clarke DJ, Bjorklund A,. 1988a. Striatal grafts in rats with unilateral neostriatal lesions-III. Recovery from dopamine-dependent motor asymmetry and deficits in skilled paw reaching. Neuroscience 24: 813-820.
-
(1988)
Neuroscience
, vol.24
, pp. 813-820
-
-
Dunnett, S.B.1
Isacson, O.2
Sirinathsinghji, D.J.3
Clarke, D.J.4
Bjorklund, A.5
-
24
-
-
0024244343
-
Striatal grafts in the ibotenic acid-lesioned neostriatum: Functional studies
-
Dunnett SB, Isacson O, Sirinathsinghji DJ, Clarke DJ, Bjorklund A,. 1988b. Striatal grafts in the ibotenic acid-lesioned neostriatum: Functional studies. Prog Brain Res 78: 39-45.
-
(1988)
Prog Brain Res
, vol.78
, pp. 39-45
-
-
Dunnett, S.B.1
Isacson, O.2
Sirinathsinghji, D.J.3
Clarke, D.J.4
Bjorklund, A.5
-
26
-
-
0029082383
-
Inactivation of the mouse Huntington's disease gene homolog Hdh
-
Duyao MP, Auerbach AB, Ryan A, Persichetti F, Barnes GT, McNeil SM, Ge P, Vonsattel JP, Gusella JF, Joyner AL, et al. 1995. Inactivation of the mouse Huntington's disease gene homolog Hdh. Science 269: 407-410.
-
(1995)
Science
, vol.269
, pp. 407-410
-
-
Duyao, M.P.1
Auerbach, A.B.2
Ryan, A.3
Persichetti, F.4
Barnes, G.T.5
McNeil, S.M.6
Ge, P.7
Vonsattel, J.P.8
Gusella, J.F.9
Joyner, A.L.10
-
27
-
-
77954075077
-
Neural differentiation and therapeutic potential of adipose tissue derived stem cells
-
Erba P, Terenghi G, Kingham PJ,. 2010. Neural differentiation and therapeutic potential of adipose tissue derived stem cells. Curr Stem Cell Res Ther 5: 153-160.
-
(2010)
Curr Stem Cell Res Ther
, vol.5
, pp. 153-160
-
-
Erba, P.1
Terenghi, G.2
Kingham, P.J.3
-
28
-
-
33746708104
-
Neural transplantation in Huntington's disease: The NEST-UK donor tissue microbiological screening program and review of the literature
-
Farrington M, Wreghitt TG, Lever AM, Dunnett SB, Rosser AE, Barker RA,. 2006. Neural transplantation in Huntington's disease: The NEST-UK donor tissue microbiological screening program and review of the literature. Cell Transplant 15: 279-294.
-
(2006)
Cell Transplant
, vol.15
, pp. 279-294
-
-
Farrington, M.1
Wreghitt, T.G.2
Lever, A.M.3
Dunnett, S.B.4
Rosser, A.E.5
Barker, R.A.6
-
29
-
-
12944288307
-
Transplanted fetal striatum in Huntington's disease: Phenotypic development and lack of pathology
-
Freeman TB, Cicchetti F, Hauser RA, Deacon TW, Li XJ, Hersch SM, Nauert GM, Sanberg PR, Kordower JH, Saporta S, Isacson O,. 2000a. Transplanted fetal striatum in Huntington's disease: Phenotypic development and lack of pathology. Proc Natl Acad Sci USA 97: 13877-13882.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13877-13882
-
-
Freeman, T.B.1
Cicchetti, F.2
Hauser, R.A.3
Deacon, T.W.4
Li, X.J.5
Hersch, S.M.6
Nauert, G.M.7
Sanberg, P.R.8
Kordower, J.H.9
Saporta, S.10
Isacson, O.11
-
30
-
-
0033647784
-
Transplantation of human fetal striatal tissue in Huntington's disease: Rationale for clinical studies
-
discussion 139-47
-
Freeman TB, Hauser RA, Willing AE, Zigova T, Sanberg PR, Saporta S,. 2000b. Transplantation of human fetal striatal tissue in Huntington's disease: Rationale for clinical studies. Novartis Found Symp 231: 129-138, discussion 139-47.
-
(2000)
Novartis Found Symp
, vol.231
, pp. 129-138
-
-
Freeman, T.B.1
Hauser, R.A.2
Willing, A.E.3
Zigova, T.4
Sanberg, P.R.5
Saporta, S.6
-
31
-
-
23244461696
-
Positron emission tomography after fetal transplantation in Huntington's disease
-
Furtado S, Sossi V, Hauser RA, Samii A, Schulzer M, Murphy CB, Freeman TB, Stoessl AJ,. 2005. Positron emission tomography after fetal transplantation in Huntington's disease. Ann Neurol 58: 331-337.
-
(2005)
Ann Neurol
, vol.58
, pp. 331-337
-
-
Furtado, S.1
Sossi, V.2
Hauser, R.A.3
Samii, A.4
Schulzer, M.5
Murphy, C.B.6
Freeman, T.B.7
Stoessl, A.J.8
-
32
-
-
49349102753
-
Development of human striatal anlagen after transplantation in a patient with Huntington's disease
-
Gallina P, Paganini M, Lombardini L, Saccardi R, Marini M, De Cristofaro MT, Pinzani P, Salvianti F, Crescioli C, Di Rita A, Bucciantini S, Mechi C, Sarchielli E, Moretti M, Piacentini S, Gritti G, Bosi A, Sorbi S, Orlandini G, Vannelli GB, Di Lorenzo N,. 2008. Development of human striatal anlagen after transplantation in a patient with Huntington's disease. Exp Neurol 313: 241-244.
-
(2008)
Exp Neurol
, vol.313
, pp. 241-244
-
-
Gallina, P.1
Paganini, M.2
Lombardini, L.3
Saccardi, R.4
Marini, M.5
De Cristofaro, M.T.6
Pinzani, P.7
Salvianti, F.8
Crescioli, C.9
Di Rita, A.10
Bucciantini, S.11
Mechi, C.12
Sarchielli, E.13
Moretti, M.14
Piacentini, S.15
Gritti, G.16
Bosi, A.17
Sorbi, S.18
Orlandini, G.19
Vannelli, G.B.20
Di Lorenzo, N.21
more..
-
33
-
-
9144221004
-
Striatal neural grafting improves cortical metabolism in Huntington's disease patients
-
Gaura V, Bachoud-Levi AC, Ribeiro MJ, Nguyen JP, Frouin V, Baudic S, Brugieres P, Mangin JF, Boisse MF, Palfi S, Cesaro P, Samson Y, Hantraye P, Peschanski M, Remy P,. 2004. Striatal neural grafting improves cortical metabolism in Huntington's disease patients. Brain 127: 65-72.
-
(2004)
Brain
, vol.127
, pp. 65-72
-
-
Gaura, V.1
Bachoud-Levi, A.C.2
Ribeiro, M.J.3
Nguyen, J.P.4
Frouin, V.5
Baudic, S.6
Brugieres, P.7
Mangin, J.F.8
Boisse, M.F.9
Palfi, S.10
Cesaro, P.11
Samson, Y.12
Hantraye, P.13
Peschanski, M.14
Remy, P.15
-
34
-
-
67349091072
-
Chemokines direct neural progenitor cell migration following striatal cell loss
-
Gordon RJ, McGregor AL, Connor B,. 2009. Chemokines direct neural progenitor cell migration following striatal cell loss. Mol Cell Neurosci 41: 219-232.
-
(2009)
Mol Cell Neurosci
, vol.41
, pp. 219-232
-
-
Gordon, R.J.1
McGregor, A.L.2
Connor, B.3
-
35
-
-
0032424883
-
Regional specificity of brain atrophy in Huntington's disease
-
Halliday GM, McRitchie DA, Macdonald V, Double KL, Trent RJ, McCusker E,. 1998. Regional specificity of brain atrophy in Huntington's disease. Exp Neurol 154: 663-672.
-
(1998)
Exp Neurol
, vol.154
, pp. 663-672
-
-
Halliday, G.M.1
McRitchie, D.A.2
MacDonald, V.3
Double, K.L.4
Trent, R.J.5
McCusker, E.6
-
36
-
-
0037066096
-
Bilateral human fetal striatal transplantation in Huntington's disease
-
Hauser RA, Furtado S, Cimino CR, Delgado H, Eichler S, Schwartz S, Scott D, Nauert GM, Soety E, Sossi V, Holt DA, Sanberg PR, Stoessl AJ, Freeman TB,. 2002. Bilateral human fetal striatal transplantation in Huntington's disease. Neurology 58: 687-695.
-
(2002)
Neurology
, vol.58
, pp. 687-695
-
-
Hauser, R.A.1
Furtado, S.2
Cimino, C.R.3
Delgado, H.4
Eichler, S.5
Schwartz, S.6
Scott, D.7
Nauert, G.M.8
Soety, E.9
Sossi, V.10
Holt, D.A.11
Sanberg, P.R.12
Stoessl, A.J.13
Freeman, T.B.14
-
37
-
-
58149189835
-
Tetrabenazine
-
Hayden MR, Leavitt BR, Yasothan U, Kirkpatrick P,. 2009. Tetrabenazine. Nat Rev Drug Discov 8: 17-18.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 17-18
-
-
Hayden, M.R.1
Leavitt, B.R.2
Yasothan, U.3
Kirkpatrick, P.4
-
39
-
-
24044442568
-
Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing
-
Hickey MA, Gallant K, Gross GG, Levine MS, Chesselet MF,. 2005. Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing. Neurobiol Dis 20: 1-11.
-
(2005)
Neurobiol Dis
, vol.20
, pp. 1-11
-
-
Hickey, M.A.1
Gallant, K.2
Gross, G.G.3
Levine, M.S.4
Chesselet, M.F.5
-
40
-
-
80555129725
-
Transplantation of patient-derived adipose stem cells in YAC128 Huntington's disease transgenic mice
-
Im W, Lee ST, Park JE, Oh HJ, Shim J, Lim J, Chu K, Kim M,. 2010. Transplantation of patient-derived adipose stem cells in YAC128 Huntington's disease transgenic mice. PLoS 2: RRN1183.
-
(2010)
PLoS
, vol.2
-
-
Im, W.1
Lee, S.T.2
Park, J.E.3
Oh, H.J.4
Shim, J.5
Lim, J.6
Chu, K.7
Kim, M.8
-
41
-
-
0030866841
-
Benefits and risks of hosting animal cells in the human brain
-
Isacson O, Breakefield XO,. 1997. Benefits and risks of hosting animal cells in the human brain. Nat Med 3: 964-969.
-
(1997)
Nat Med
, vol.3
, pp. 964-969
-
-
Isacson, O.1
Breakefield, X.O.2
-
42
-
-
0022551746
-
Graft-induced behavioral recovery in an animal model of Huntington disease
-
Isacson O, Dunnett SB, Bjorklund A,. 1986. Graft-induced behavioral recovery in an animal model of Huntington disease. Proc Natl Acad Sci USA 83: 2728-2732.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 2728-2732
-
-
Isacson, O.1
Dunnett, S.B.2
Bjorklund, A.3
-
43
-
-
33847385967
-
Time of transplantation and cell preparation determine neural stem cell survival in a mouse model of Huntington's disease
-
Johann V, Schiefer J, Sass C, Mey J, Brook G, Kruttgen A, Schlangen C, Bernreuther C, Schachner M, Dihne M, Kosinski CM,. 2007. Time of transplantation and cell preparation determine neural stem cell survival in a mouse model of Huntington's disease. Exp Brain Res 177: 458-470.
-
(2007)
Exp Brain Res
, vol.177
, pp. 458-470
-
-
Johann, V.1
Schiefer, J.2
Sass, C.3
Mey, J.4
Brook, G.5
Kruttgen, A.6
Schlangen, C.7
Bernreuther, C.8
Schachner, M.9
Dihne, M.10
Kosinski, C.M.11
-
44
-
-
1042276562
-
Evidence for more widespread cerebral pathology in early HD: An MRI-based morphometric analysis
-
author reply 524
-
Kassubek J, Gaus W, Landwehrmeyer GB,. 2004. Evidence for more widespread cerebral pathology in early HD: An MRI-based morphometric analysis. Neurology 62: 523-524, author reply 524.
-
(2004)
Neurology
, vol.62
, pp. 523-524
-
-
Kassubek, J.1
Gaus, W.2
Landwehrmeyer, G.B.3
-
45
-
-
0034589152
-
Striatal tissue transplantation in non-human primates
-
Kendall AL, Hantraye P, Palfi S,. 2000. Striatal tissue transplantation in non-human primates. Prog Brain Res 127: 381-404.
-
(2000)
Prog Brain Res
, vol.127
, pp. 381-404
-
-
Kendall, A.L.1
Hantraye, P.2
Palfi, S.3
-
46
-
-
55249107197
-
Alloimmunisation to donor antigens and immune rejection following foetal neural grafts to the brain in patients with Huntington's disease
-
Krystkowiak P, Gaura V, Labalette M, Rialland A, Remy P, Peschanski M, Bachoud-Levi AC,. 2007. Alloimmunisation to donor antigens and immune rejection following foetal neural grafts to the brain in patients with Huntington's disease. PLoS ONE 2: e166.
-
(2007)
PLoS ONE
, vol.2
-
-
Krystkowiak, P.1
Gaura, V.2
Labalette, M.3
Rialland, A.4
Remy, P.5
Peschanski, M.6
Bachoud-Levi, A.C.7
-
47
-
-
84855920796
-
Bone marrow transplantation confers modest benefits in mouse models of Huntington's disease
-
Kwan W, Magnusson A, Chou A, Adame A, Carson MJ, Kohsaka S, Masliah E, Moller T, Ransohoff R, Tabrizi SJ, Bjorkqvist M, Muchowski PJ,. 2012. Bone marrow transplantation confers modest benefits in mouse models of Huntington's disease. J Neurosci 32: 133-142.
-
(2012)
J Neurosci
, vol.32
, pp. 133-142
-
-
Kwan, W.1
Magnusson, A.2
Chou, A.3
Adame, A.4
Carson, M.J.5
Kohsaka, S.6
Masliah, E.7
Moller, T.8
Ransohoff, R.9
Tabrizi, S.J.10
Bjorkqvist, M.11
Muchowski, P.J.12
-
48
-
-
0017183963
-
Morphometric studies of the neuropathological changes in choreatic diseases
-
Lange H, Thorner G, Hopf A, Schroder KF,. 1976. Morphometric studies of the neuropathological changes in choreatic diseases. J Neurol Sci 28: 401-425.
-
(1976)
J Neurol Sci
, vol.28
, pp. 401-425
-
-
Lange, H.1
Thorner, G.2
Hopf, A.3
Schroder, K.F.4
-
49
-
-
0035127907
-
Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo
-
Leavitt BR, Guttman JA, Hodgson JG, Kimel GH, Singaraja R, Vogl AW, Hayden MR,. 2001. Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo. Am J Hum Genet 68: 313-324.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 313-324
-
-
Leavitt, B.R.1
Guttman, J.A.2
Hodgson, J.G.3
Kimel, G.H.4
Singaraja, R.5
Vogl, A.W.6
Hayden, M.R.7
-
50
-
-
33645100553
-
Wild-type huntingtin protects neurons from excitotoxicity
-
Leavitt BR, van Raamsdonk JM, Shehadeh J, Fernandes H, Murphy Z, Graham RK, Wellington CL, Raymond LA, Hayden MR,. 2006. Wild-type huntingtin protects neurons from excitotoxicity. J Neurochem 96: 1121-1129.
-
(2006)
J Neurochem
, vol.96
, pp. 1121-1129
-
-
Leavitt, B.R.1
Van Raamsdonk, J.M.2
Shehadeh, J.3
Fernandes, H.4
Murphy, Z.5
Graham, R.K.6
Wellington, C.L.7
Raymond, L.A.8
Hayden, M.R.9
-
51
-
-
1542267796
-
Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease
-
Lee WC, Yoshihara M, Littleton JT,. 2004. Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease. Proc Natl Acad Sci USA 101: 3224-3229.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3224-3229
-
-
Lee, W.C.1
Yoshihara, M.2
Littleton, J.T.3
-
52
-
-
20144381234
-
Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model
-
Lee ST, Chu K, Park JE, Lee K, Kang L, Kim SU, Kim M,. 2005. Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model. Neurosci Res 52: 243-249.
-
(2005)
Neurosci Res
, vol.52
, pp. 243-249
-
-
Lee, S.T.1
Chu, K.2
Park, J.E.3
Lee, K.4
Kang, L.5
Kim, S.U.6
Kim, M.7
-
53
-
-
33644780840
-
Noninvasive method of immortalized neural stem-like cell transplantation in an experimental model of Huntington's disease
-
Lee ST, Park JE, Lee K, Kang L, Chu K, Kim SU, Kim M, Roh JK,. 2006. Noninvasive method of immortalized neural stem-like cell transplantation in an experimental model of Huntington's disease. J Neurosci Methods 152: 250-254.
-
(2006)
J Neurosci Methods
, vol.152
, pp. 250-254
-
-
Lee, S.T.1
Park, J.E.2
Lee, K.3
Kang, L.4
Chu, K.5
Kim, S.U.6
Kim, M.7
Roh, J.K.8
-
54
-
-
72949093579
-
Slowed progression in models of Huntington disease by adipose stem cell transplantation
-
Lee ST, Chu K, Jung KH, Im WS, Park JE, Lim HC, Won CH, Shin SH, Lee SK, Kim M, Roh JK,. 2009. Slowed progression in models of Huntington disease by adipose stem cell transplantation. Ann Neurol 66: 671-681.
-
(2009)
Ann Neurol
, vol.66
, pp. 671-681
-
-
Lee, S.T.1
Chu, K.2
Jung, K.H.3
Im, W.S.4
Park, J.E.5
Lim, H.C.6
Won, C.H.7
Shin, S.H.8
Lee, S.K.9
Kim, M.10
Roh, J.K.11
-
55
-
-
0042527172
-
Autologous adult bone marrow stem cell transplantation in an animal model of huntington's disease: Behavioral and morphological outcomes
-
Lescaudron L, Unni D, Dunbar GL,. 2003. Autologous adult bone marrow stem cell transplantation in an animal model of huntington's disease: Behavioral and morphological outcomes. Int J Neurosci 113: 945-956.
-
(2003)
Int J Neurosci
, vol.113
, pp. 945-956
-
-
Lescaudron, L.1
Unni, D.2
Dunbar, G.L.3
-
56
-
-
0033571743
-
Enhanced sensitivity to N-methyl- D -aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease
-
Levine MS, Klapstein GJ, Koppel A, Gruen E, Cepeda C, Vargas ME, Jokel ES, Carpenter EM, Zanjani H, Hurst RS, Efstratiadis A, Zeitlin S, Chesselet MF,. 1999. Enhanced sensitivity to N-methyl- D -aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease. J Neurosci Res 58: 515-532.
-
(1999)
J Neurosci Res
, vol.58
, pp. 515-532
-
-
Levine, M.S.1
Klapstein, G.J.2
Koppel, A.3
Gruen, E.4
Cepeda, C.5
Vargas, M.E.6
Jokel, E.S.7
Carpenter, E.M.8
Zanjani, H.9
Hurst, R.S.10
Efstratiadis, A.11
Zeitlin, S.12
Chesselet, M.F.13
-
57
-
-
1242338856
-
Huntingtin-protein interactions and the pathogenesis of Huntington's disease
-
Li SH, Li XJ,. 2004. Huntingtin-protein interactions and the pathogenesis of Huntington's disease. Trends Genet 20: 146-154.
-
(2004)
Trends Genet
, vol.20
, pp. 146-154
-
-
Li, S.H.1
Li, X.J.2
-
58
-
-
0035862896
-
Neurological abnormalities in a knock-in mouse model of Huntington's disease
-
Lin CH, Tallaksen-Greene S, Chien WM, Cearley JA, Jackson WS, Crouse AB, Ren S, Li XJ, Albin RL, Detloff PJ,. 2001. Neurological abnormalities in a knock-in mouse model of Huntington's disease. Hum Mol Genet 10: 137-144.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 137-144
-
-
Lin, C.H.1
Tallaksen-Greene, S.2
Chien, W.M.3
Cearley, J.A.4
Jackson, W.S.5
Crouse, A.B.6
Ren, S.7
Li, X.J.8
Albin, R.L.9
Detloff, P.J.10
-
59
-
-
79961147771
-
Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models
-
Lin YT, Chern Y, Shen CK, Wen HL, Chang YC, Li H, Cheng TH, Hsieh-Li HM,. 2011. Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models. PLoS ONE 6: e22924.
-
(2011)
PLoS ONE
, vol.6
-
-
Lin, Y.T.1
Chern, Y.2
Shen, C.K.3
Wen, H.L.4
Chang, Y.C.5
Li, H.6
Cheng, T.H.7
Hsieh-Li, H.M.8
-
60
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. the Huntington's Disease Collaborative Research Group
-
MacDonald ME, Ambrose CM, Duyao MP, Myers RH, Lin C, Srinidhi L, Barnes G, Taylor SA, James M, Groot N, MacFarlane H, Jenkins B,. 1993. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group. Cell 72: 971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
MacDonald, M.E.1
Ambrose, C.M.2
Duyao, M.P.3
Myers, R.H.4
Lin, C.5
Srinidhi, L.6
Barnes, G.7
Taylor, S.A.8
James, M.9
Groot, N.10
MacFarlane, H.11
Jenkins, B.12
-
61
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L, Sathasivam K, Seller M, Cozens B, Harper A, Hetherington C, Lawton M, Trottier Y, Lehrach H, Davies SW, Bates GP,. 1996. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87: 493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
62
-
-
0029905329
-
Protection of the neostriatum against excitotoxic damage by neurotrophin-producing, genetically modified neural stem cells
-
Martinez-Serrano A, Bjorklund A,. 1996. Protection of the neostriatum against excitotoxic damage by neurotrophin-producing, genetically modified neural stem cells. J Neurosci 16: 4604-4616.
-
(1996)
J Neurosci
, vol.16
, pp. 4604-4616
-
-
Martinez-Serrano, A.1
Bjorklund, A.2
-
63
-
-
3042721905
-
Human neural stem cell transplants improve motor function in a rat model of Huntington's disease
-
McBride JL, Behrstock SP, Chen EY, Jakel RJ, Siegel I, Svendsen CN, Kordower JH,. 2004. Human neural stem cell transplants improve motor function in a rat model of Huntington's disease. J Comp Neurol 475: 211-219.
-
(2004)
J Comp Neurol
, vol.475
, pp. 211-219
-
-
McBride, J.L.1
Behrstock, S.P.2
Chen, E.Y.3
Jakel, R.J.4
Siegel, I.5
Svendsen, C.N.6
Kordower, J.H.7
-
64
-
-
0037107191
-
Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice
-
Menalled LB, Sison JD, Wu Y, Olivieri M, Li XJ, Li H, Zeitlin S, Chesselet MF,. 2002. Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice. J Neurosci 22: 8266-8276.
-
(2002)
J Neurosci
, vol.22
, pp. 8266-8276
-
-
Menalled, L.B.1
Sison, J.D.2
Wu, Y.3
Olivieri, M.4
Li, X.J.5
Li, H.6
Zeitlin, S.7
Chesselet, M.F.8
-
65
-
-
0034958203
-
Progressive formation of inclusions in the striatum and hippocampus of mice transgenic for the human Huntington's disease mutation
-
Morton AJ, Lagan MA, Skepper JN, Dunnett SB,. 2000. Progressive formation of inclusions in the striatum and hippocampus of mice transgenic for the human Huntington's disease mutation. J Neurocytol 29: 679-702.
-
(2000)
J Neurocytol
, vol.29
, pp. 679-702
-
-
Morton, A.J.1
Lagan, M.A.2
Skepper, J.N.3
Dunnett, S.B.4
-
66
-
-
0021829313
-
Late onset of Huntington's disease
-
Myers RH, Sax DS, Schoenfeld M, Bird ED, Wolf PA, Vonsattel JP, White RF, Martin JB,. 1985. Late onset of Huntington's disease. J Neurol Neurosurg Psychiatry 48: 530-534.
-
(1985)
J Neurol Neurosurg Psychiatry
, vol.48
, pp. 530-534
-
-
Myers, R.H.1
Sax, D.S.2
Schoenfeld, M.3
Bird, E.D.4
Wolf, P.A.5
Vonsattel, J.P.6
White, R.F.7
Martin, J.B.8
-
67
-
-
0034015127
-
Fetal tissue transplants in animal models of Huntington's disease: The effects on damaged neuronal circuitry and behavioral deficits
-
Nakao N, Itakura T,. 2000. Fetal tissue transplants in animal models of Huntington's disease: The effects on damaged neuronal circuitry and behavioral deficits. Prog Neurobiol 61: 313-338.
-
(2000)
Prog Neurobiol
, vol.61
, pp. 313-338
-
-
Nakao, N.1
Itakura, T.2
-
68
-
-
0029055717
-
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
-
Nasir J, Floresco SB, O'Kusky JR, Diewert VM, Richman JM, Zeisler J, Borowski A, Marth JD, Phillips AG, Hayden MR,. 1995. Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes. Cell 81: 811-823.
-
(1995)
Cell
, vol.81
, pp. 811-823
-
-
Nasir, J.1
Floresco, S.B.2
O'Kusky, J.R.3
Diewert, V.M.4
Richman, J.M.5
Zeisler, J.6
Borowski, A.7
Marth, J.D.8
Phillips, A.G.9
Hayden, M.R.10
-
69
-
-
0345304253
-
Molecular and behavioral analysis of the R6/1 Huntington's disease transgenic mouse
-
Naver B, Stub C, Moller M, Fenger K, Hansen AK, Hasholt L, Sorensen SA,. 2003. Molecular and behavioral analysis of the R6/1 Huntington's disease transgenic mouse. Neuroscience 122: 1049-1057.
-
(2003)
Neuroscience
, vol.122
, pp. 1049-1057
-
-
Naver, B.1
Stub, C.2
Moller, M.3
Fenger, K.4
Hansen, A.K.5
Hasholt, L.6
Sorensen, S.A.7
-
70
-
-
33750210519
-
Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington's disease
-
Nguyen HP, Kobbe P, Rahne H, Worpel T, Jager B, Stephan M, Pabst R, Holzmann C, Riess O, Korr H, Kantor O, Petrasch-Parwez E, Wetzel R, Osmand A, von Horsten S,. 2006. Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington's disease. Hum Mol Genet 15: 3177-3194.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 3177-3194
-
-
Nguyen, H.P.1
Kobbe, P.2
Rahne, H.3
Worpel, T.4
Jager, B.5
Stephan, M.6
Pabst, R.7
Holzmann, C.8
Riess, O.9
Korr, H.10
Kantor, O.11
Petrasch-Parwez, E.12
Wetzel, R.13
Osmand, A.14
Von Horsten, S.15
-
71
-
-
0031902287
-
Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease
-
Palfi S, Conde F, Riche D, Brouillet E, Dautry C, Mittoux V, Chibois A, Peschanski M, Hantraye P,. 1998. Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease. Nat Med 4: 963-966.
-
(1998)
Nat Med
, vol.4
, pp. 963-966
-
-
Palfi, S.1
Conde, F.2
Riche, D.3
Brouillet, E.4
Dautry, C.5
Mittoux, V.6
Chibois, A.7
Peschanski, M.8
Hantraye, P.9
-
72
-
-
58949085531
-
Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease
-
Pang TY, Du X, Zajac MS, Howard ML, Hannan AJ,. 2009. Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease. Hum Mol Genet 18: 753-766.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 753-766
-
-
Pang, T.Y.1
Du, X.2
Zajac, M.S.3
Howard, M.L.4
Hannan, A.J.5
-
73
-
-
33845976361
-
Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: Optical neuroimage tracking of brain-grafted cells
-
Pineda JR, Rubio N, Akerud P, Urban N, Badimon L, Arenas E, Alberch J, Blanco J, Canals JM,. 2007. Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: Optical neuroimage tracking of brain-grafted cells. Gene Ther 14: 118-128.
-
(2007)
Gene Ther
, vol.14
, pp. 118-128
-
-
Pineda, J.R.1
Rubio, N.2
Akerud, P.3
Urban, N.4
Badimon, L.5
Arenas, E.6
Alberch, J.7
Blanco, J.8
Canals, J.M.9
-
74
-
-
0023148062
-
Afferent and efferent connections of striatal grafts implanted into the ibotenic acid lesioned neostriatum in adult rats
-
Pritzel M, Isacson O, Brundin P, Wiklund L, Bjorklund A,. 1986. Afferent and efferent connections of striatal grafts implanted into the ibotenic acid lesioned neostriatum in adult rats. Exp Brain Res 65: 112-126.
-
(1986)
Exp Brain Res
, vol.65
, pp. 112-126
-
-
Pritzel, M.1
Isacson, O.2
Brundin, P.3
Wiklund, L.4
Bjorklund, A.5
-
76
-
-
34250659732
-
Huntington's disease: Pathological mechanisms and therapeutic strategies
-
Ramaswamy S, Shannon KM, Kordower JH,. 2007b. Huntington's disease: Pathological mechanisms and therapeutic strategies. Cell Transplant 16: 301-312.
-
(2007)
Cell Transplant
, vol.16
, pp. 301-312
-
-
Ramaswamy, S.1
Shannon, K.M.2
Kordower, J.H.3
-
77
-
-
12144287799
-
Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells
-
Rehman J, Traktuev D, Li J, Merfeld-Clauss S, Temm-Grove CJ, Bovenkerk JE, Pell CL, Johnstone BH, Considine RV, March KL,. 2004. Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells. Circulation 109: 1292-1298.
-
(2004)
Circulation
, vol.109
, pp. 1292-1298
-
-
Rehman, J.1
Traktuev, D.2
Li, J.3
Merfeld-Clauss, S.4
Temm-Grove, C.J.5
Bovenkerk, J.E.6
Pell, C.L.7
Johnstone, B.H.8
Considine, R.V.9
March, K.L.10
-
78
-
-
48249145755
-
Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease
-
Reuter I, Tai YF, Pavese N, Chaudhuri KR, Mason S, Polkey CE, Clough C, Brooks DJ, Barker RA, Piccini P,. 2008. Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease. J Neurol Neurosurg Psychiatry 79: 948-951.
-
(2008)
J Neurol Neurosurg Psychiatry
, vol.79
, pp. 948-951
-
-
Reuter, I.1
Tai, Y.F.2
Pavese, N.3
Chaudhuri, K.R.4
Mason, S.5
Polkey, C.E.6
Clough, C.7
Brooks, D.J.8
Barker, R.A.9
Piccini, P.10
-
79
-
-
33646164883
-
Preservation of striatal tissue and behavioral function after neural stem cell transplantation in a rat model of Huntington's disease
-
Roberts TJ, Price J, Williams SC, Modo M,. 2006. Preservation of striatal tissue and behavioral function after neural stem cell transplantation in a rat model of Huntington's disease. Neuroscience 139: 1187-1199.
-
(2006)
Neuroscience
, vol.139
, pp. 1187-1199
-
-
Roberts, T.J.1
Price, J.2
Williams, S.C.3
Modo, M.4
-
80
-
-
0141528727
-
Neural transplantation in patients with Huntington's disease
-
Rosser AE, Dunnett SB,. 2003. Neural transplantation in patients with Huntington's disease. CNS Drugs 17: 853-867.
-
(2003)
CNS Drugs
, vol.17
, pp. 853-867
-
-
Rosser, A.E.1
Dunnett, S.B.2
-
81
-
-
0036904801
-
Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report ISRCTN no 36485475
-
Rosser AE, Barker RA, Harrower T, Watts C, Farrington M, Ho AK, Burnstein RM, Menon DK, Gillard JH, Pickard J, Dunnett SB,. 2002. Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report ISRCTN no 36485475. J Neurol Neurosurg Psychiatry 73: 678-685.
-
(2002)
J Neurol Neurosurg Psychiatry
, vol.73
, pp. 678-685
-
-
Rosser, A.E.1
Barker, R.A.2
Harrower, T.3
Watts, C.4
Farrington, M.5
Ho, A.K.6
Burnstein, R.M.7
Menon, D.K.8
Gillard, J.H.9
Pickard, J.10
Dunnett, S.B.11
-
82
-
-
0029997090
-
Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats
-
Rubinsztein DC, Leggo J, Coles R, Almqvist E, Biancalana V, Cassiman JJ, Chotai K, Connarty M, Crauford D, Curtis A, Curtis D, Davidson MJ, Differ AM, Dode C, Dodge A, Frontali M, Ranen NG, Stine OC, Sherr M, Abbott MH, Franz ML, Graham CA, Harper PS, Hedreen JC, Hayden MR, et al. 1996. Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats. Am J Hum Genet 59: 16-22.
-
(1996)
Am J Hum Genet
, vol.59
, pp. 16-22
-
-
Rubinsztein, D.C.1
Leggo, J.2
Coles, R.3
Almqvist, E.4
Biancalana, V.5
Cassiman, J.J.6
Chotai, K.7
Connarty, M.8
Crauford, D.9
Curtis, A.10
Curtis, D.11
Davidson, M.J.12
Differ, A.M.13
Dode, C.14
Dodge, A.15
Frontali, M.16
Ranen, N.G.17
Stine, O.C.18
Sherr, M.19
Abbott, M.H.20
Franz, M.L.21
Graham, C.A.22
Harper, P.S.23
Hedreen, J.C.24
Hayden, M.R.25
more..
-
83
-
-
2342562572
-
Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease
-
Ryu JK, Kim J, Cho SJ, Hatori K, Nagai A, Choi HB, Lee MC, McLarnon JG, Kim SU,. 2004. Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease. Neurobiol Dis 16: 68-77.
-
(2004)
Neurobiol Dis
, vol.16
, pp. 68-77
-
-
Ryu, J.K.1
Kim, J.2
Cho, S.J.3
Hatori, K.4
Nagai, A.5
Choi, H.B.6
Lee, M.C.7
McLarnon, J.G.8
Kim, S.U.9
-
84
-
-
0024024251
-
3-Hydroxyanthranilate oxygenase activity is increased in the brains of Huntington disease victims
-
Schwarcz R, Okuno E, White RJ, Bird ED, Whetsell WO, Jr., 1988. 3-Hydroxyanthranilate oxygenase activity is increased in the brains of Huntington disease victims. Proc Natl Acad Sci USA 85: 4079-4081.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 4079-4081
-
-
Schwarcz, R.1
Okuno, E.2
White, R.J.3
Bird, E.D.4
Whetsell Jr., W.O.5
-
85
-
-
0029034511
-
Widespread expression of Huntington's disease gene (IT15) protein product
-
Sharp AH, Loev SJ, Schilling G, Li SH, Li XJ, Bao J, Wagster MV, Kotzuk JA, Steiner JP, Lo A, et al. 1995. Widespread expression of Huntington's disease gene (IT15) protein product. Neuron 14: 1065-1074.
-
(1995)
Neuron
, vol.14
, pp. 1065-1074
-
-
Sharp, A.H.1
Loev, S.J.2
Schilling, G.3
Li, S.H.4
Li, X.J.5
Bao, J.6
Wagster, M.V.7
Kotzuk, J.A.8
Steiner, J.P.9
Lo, A.10
-
86
-
-
0023900877
-
Striatal grafts in rats with unilateral neostriatal lesions - II. in vivo monitoring of GABA release in globus pallidus and substantia nigra
-
Sirinathsinghji DJ, Dunnett SB, Isacson O, Clarke DJ, Kendrick K, Bjorklund A,. 1988. Striatal grafts in rats with unilateral neostriatal lesions-II. In vivo monitoring of GABA release in globus pallidus and substantia nigra. Neuroscience 24: 803-811.
-
(1988)
Neuroscience
, vol.24
, pp. 803-811
-
-
Sirinathsinghji, D.J.1
Dunnett, S.B.2
Isacson, O.3
Clarke, D.J.4
Kendrick, K.5
Bjorklund, A.6
-
87
-
-
10744227174
-
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease
-
Slow EJ, van Raamsdonk J, Rogers D, Coleman SH, Graham RK, Deng Y, Oh R, Bissada N, Hossain SM, Yang YZ, Li XJ, Simpson EM, Gutekunst CA, Leavitt BR, Hayden MR,. 2003. Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease. Hum Mol Genet 12: 1555-1567.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1555-1567
-
-
Slow, E.J.1
Van Raamsdonk, J.2
Rogers, D.3
Coleman, S.H.4
Graham, R.K.5
Deng, Y.6
Oh, R.7
Bissada, N.8
Hossain, S.M.9
Yang, Y.Z.10
Li, X.J.11
Simpson, E.M.12
Gutekunst, C.A.13
Leavitt, B.R.14
Hayden, M.R.15
-
88
-
-
77949631994
-
Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease
-
Snyder BR, Chiu AM, Prockop DJ, Chan AW,. 2010. Human multipotent stromal cells (MSCs) increase neurogenesis and decrease atrophy of the striatum in a transgenic mouse model for Huntington's disease. PLoS ONE 5: e9347.
-
(2010)
PLoS ONE
, vol.5
-
-
Snyder, B.R.1
Chiu, A.M.2
Prockop, D.J.3
Chan, A.W.4
-
89
-
-
34547489963
-
Human embryonic stem cell-derived neural precursor transplants attenuate apomorphine-induced rotational behavior in rats with unilateral quinolinic acid lesions
-
Song J, Lee ST, Kang W, Park JE, Chu K, Lee SE, Hwang T, Chung H, Kim M,. 2007. Human embryonic stem cell-derived neural precursor transplants attenuate apomorphine-induced rotational behavior in rats with unilateral quinolinic acid lesions. Neurosci Lett 423: 58-61.
-
(2007)
Neurosci Lett
, vol.423
, pp. 58-61
-
-
Song, J.1
Lee, S.T.2
Kang, W.3
Park, J.E.4
Chu, K.5
Lee, S.E.6
Hwang, T.7
Chung, H.8
Kim, M.9
-
90
-
-
24144475005
-
Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice
-
Stack EC, Kubilus JK, Smith K, Cormier K, Del Signore SJ, Guelin E, Ryu H, Hersch SM, Ferrante RJ,. 2005. Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice. J Comp Neurol 490: 354-370.
-
(2005)
J Comp Neurol
, vol.490
, pp. 354-370
-
-
Stack, E.C.1
Kubilus, J.K.2
Smith, K.3
Cormier, K.4
Del Signore, S.J.5
Guelin, E.6
Ryu, H.7
Hersch, S.M.8
Ferrante, R.J.9
-
91
-
-
0029066045
-
Effects of striatal excitotoxicity on huntingtin-like immunoreactivity
-
Tatter SB, Galpern WR, Hoogeveen AT, Isacson O,. 1995. Effects of striatal excitotoxicity on huntingtin-like immunoreactivity. Neuroreport 6: 1125-1129.
-
(1995)
Neuroreport
, vol.6
, pp. 1125-1129
-
-
Tatter, S.B.1
Galpern, W.R.2
Hoogeveen, A.T.3
Isacson, O.4
-
92
-
-
77950828711
-
Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease
-
Thu DC, Oorschot DE, Tippett LJ, Nana AL, Hogg VM, Synek BJ, Luthi-Carter R, Waldvogel HJ, Faull RL,. 2010. Cell loss in the motor and cingulate cortex correlates with symptomatology in Huntington's disease. Brain 133: 1094-1110.
-
(2010)
Brain
, vol.133
, pp. 1094-1110
-
-
Thu, D.C.1
Oorschot, D.E.2
Tippett, L.J.3
Nana, A.L.4
Hogg, V.M.5
Synek, B.J.6
Luthi-Carter, R.7
Waldvogel, H.J.8
Faull, R.L.9
-
93
-
-
0022453076
-
Juvenile Huntington disease
-
van Dijk JG, van der Velde EA, Roos RA, Bruyn GW,. 1986. Juvenile Huntington disease. Hum Genet 73: 235-239.
-
(1986)
Hum Genet
, vol.73
, pp. 235-239
-
-
Van Dijk, J.G.1
Van Der Velde, E.A.2
Roos, R.A.3
Bruyn, G.W.4
-
94
-
-
17644368893
-
Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease
-
Van Raamsdonk JM, Pearson J, Slow EJ, Hossain SM, Leavitt BR, Hayden MR,. 2005. Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease. J Neurosci 25: 4169-4180.
-
(2005)
J Neurosci
, vol.25
, pp. 4169-4180
-
-
Van Raamsdonk, J.M.1
Pearson, J.2
Slow, E.J.3
Hossain, S.M.4
Leavitt, B.R.5
Hayden, M.R.6
-
95
-
-
79961238903
-
Differential fate and functional outcome of lithium chloride primed adult neural progenitor cell transplants in a rat model of Huntington disease
-
Vazey EM, Connor B,. 2010. Differential fate and functional outcome of lithium chloride primed adult neural progenitor cell transplants in a rat model of Huntington disease. Stem Cell Res Ther 1: 41.
-
(2010)
Stem Cell Res Ther
, vol.1
, pp. 41
-
-
Vazey, E.M.1
Connor, B.2
-
96
-
-
33745235762
-
Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease
-
Vazey EM, Chen K, Hughes SM, Connor B,. 2006. Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease. Exp Neurol 199: 384-396.
-
(2006)
Exp Neurol
, vol.199
, pp. 384-396
-
-
Vazey, E.M.1
Chen, K.2
Hughes, S.M.3
Connor, B.4
-
97
-
-
78349259276
-
Comparison of transplant efficiency between spontaneously derived and noggin-primed human embryonic stem cell neural precursors in the quinolinic acid rat model of Huntington's disease
-
Vazey EM, Dottori M, Jamshidi P, Tomas D, Pera MF, Horne M, Connor B,. 2010. Comparison of transplant efficiency between spontaneously derived and noggin-primed human embryonic stem cell neural precursors in the quinolinic acid rat model of Huntington's disease. Cell Transplant 19: 1055-1062.
-
(2010)
Cell Transplant
, vol.19
, pp. 1055-1062
-
-
Vazey, E.M.1
Dottori, M.2
Jamshidi, P.3
Tomas, D.4
Pera, M.F.5
Horne, M.6
Connor, B.7
-
98
-
-
0037444426
-
Transgenic rat model of Huntington's disease
-
von Horsten S, Schmitt I, Nguyen HP, Holzmann C, Schmidt T, Walther T, Bader M, Pabst R, Kobbe P, Krotova J, Stiller D, Kask A, Vaarmann A, Rathke-Hartlieb S, Schulz JB, Grasshoff U, Bauer I, Vieira-Saecker AM, Paul M, Jones L, Lindenberg KS, Landwehrmeyer B, Bauer A, Li XJ, Riess O,. 2003. Transgenic rat model of Huntington's disease. Hum Mol Genet 12: 617-624.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 617-624
-
-
Von Horsten, S.1
Schmitt, I.2
Nguyen, H.P.3
Holzmann, C.4
Schmidt, T.5
Walther, T.6
Bader, M.7
Pabst, R.8
Kobbe, P.9
Krotova, J.10
Stiller, D.11
Kask, A.12
Vaarmann, A.13
Rathke-Hartlieb, S.14
Schulz, J.B.15
Grasshoff, U.16
Bauer, I.17
Vieira-Saecker, A.M.18
Paul, M.19
Jones, L.20
Lindenberg, K.S.21
Landwehrmeyer, B.22
Bauer, A.23
Li, X.J.24
Riess, O.25
more..
-
100
-
-
0022395922
-
Neuropathological classification of Huntington's disease
-
Vonsattel JP, Myers RH, Stevens TJ, Ferrante RJ, Bird ED, Richardson EP, Jr., 1985. Neuropathological classification of Huntington's disease. J Neuropathol Exp Neurol 44: 559-577.
-
(1985)
J Neuropathol Exp Neurol
, vol.44
, pp. 559-577
-
-
Vonsattel, J.P.1
Myers, R.H.2
Stevens, T.J.3
Ferrante, R.J.4
Bird, E.D.5
Richardson Jr., E.P.6
-
101
-
-
33846225133
-
Huntington's disease
-
Walker FO,. 2007. Huntington's disease. Lancet 369: 218-228.
-
(2007)
Lancet
, vol.369
, pp. 218-228
-
-
Walker, F.O.1
-
102
-
-
33749334622
-
Human progenitor cells from bone marrow or adipose tissue produce VEGF, HGF, and IGF-I in response to TNF by a p38 MAPK-dependent mechanism
-
Wang M, Crisostomo PR, Herring C, Meldrum KK, Meldrum DR,. 2006. Human progenitor cells from bone marrow or adipose tissue produce VEGF, HGF, and IGF-I in response to TNF by a p38 MAPK-dependent mechanism. Am J Physiol Regul Integr Comp Physiol 291: R880-R884.
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.291
-
-
Wang, M.1
Crisostomo, P.R.2
Herring, C.3
Meldrum, K.K.4
Meldrum, D.R.5
-
103
-
-
0037087771
-
Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice
-
Wheeler VC, Gutekunst CA, Vrbanac V, Lebel LA, Schilling G, Hersch S, Friedlander RM, Gusella JF, Vonsattel JP, Borchelt DR, MacDonald ME,. 2002. Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice. Hum Mol Genet 11: 633-640.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 633-640
-
-
Wheeler, V.C.1
Gutekunst, C.A.2
Vrbanac, V.3
Lebel, L.A.4
Schilling, G.5
Hersch, S.6
Friedlander, R.M.7
Gusella, J.F.8
Vonsattel, J.P.9
Borchelt, D.R.10
MacDonald, M.E.11
-
104
-
-
10144229354
-
A novel azulenyl nitrone antioxidant protects against MPTP and 3-nitropropionic acid neurotoxicities
-
Yang L, Calingasan NY, Chen J, Ley JJ, Becker DA, Beal MF,. 2005. A novel azulenyl nitrone antioxidant protects against MPTP and 3-nitropropionic acid neurotoxicities. Exp Neurol 191: 86-93.
-
(2005)
Exp Neurol
, vol.191
, pp. 86-93
-
-
Yang, L.1
Calingasan, N.Y.2
Chen, J.3
Ley, J.J.4
Becker, D.A.5
Beal, M.F.6
-
105
-
-
45149105779
-
Towards a transgenic model of Huntington's disease in a non-human primate
-
Yang SH, Cheng PH, Banta H, Piotrowska-Nitsche K, Yang JJ, Cheng EC, Snyder B, Larkin K, Liu J, Orkin J, Fang ZH, Smith Y, Bachevalier J, Zola SM, Li SH, Li XJ, Chan AW,. 2008. Towards a transgenic model of Huntington's disease in a non-human primate. Nature 453: 921-924.
-
(2008)
Nature
, vol.453
, pp. 921-924
-
-
Yang, S.H.1
Cheng, P.H.2
Banta, H.3
Piotrowska-Nitsche, K.4
Yang, J.J.5
Cheng, E.C.6
Snyder, B.7
Larkin, K.8
Liu, J.9
Orkin, J.10
Fang, Z.H.11
Smith, Y.12
Bachevalier, J.13
Zola, S.M.14
Li, S.H.15
Li, X.J.16
Chan, A.W.17
-
106
-
-
78649375616
-
Neural potential of adipose stem cells
-
Zavan B, Vindigni V, Gardin C, D'Avella D, Della Puppa A, Abatangelo G, Cortivo R,. 2010. Neural potential of adipose stem cells. Discov Med 10: 37-43.
-
(2010)
Discov Med
, vol.10
, pp. 37-43
-
-
Zavan, B.1
Vindigni, V.2
Gardin, C.3
D'Avella, D.4
Della Puppa, A.5
Abatangelo, G.6
Cortivo, R.7
-
107
-
-
84993912315
-
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
-
Zeitlin S, Liu JP, Chapman DL, Papaioannou VE, Efstratiadis A,. 1995. Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue. Nat Genet 11: 155-163.
-
(1995)
Nat Genet
, vol.11
, pp. 155-163
-
-
Zeitlin, S.1
Liu, J.P.2
Chapman, D.L.3
Papaioannou, V.E.4
Efstratiadis, A.5
-
108
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, MacDonald ME, Friedlander RM, Silani V, Hayden MR, Timmusk T, Sipione S, Cattaneo E,. 2001. Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 293: 493-498.
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
Timmusk, T.11
Sipione, S.12
Cattaneo, E.13
|