Bilateral human fetal striatal transplantation in Huntington's disease

Neurology

Volumn 58, Issue 5, 2002, Pages 687-695

  Hauser, R A ^a,b   Furtado, S ^f   Cimino, C R ^b   Delgado, H ^a   Eichler, S ^d   Schwartz, S ^c   Scott, D ^b,d   Nauert, G M ^d,e   Soety, E ^b   Sossi, V ^f   Holt, D A ^b   Sanberg, P R ^b   Stoessl, A J ^f   Freeman, T B ^b,d  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d Tampa General Healthcare   (United States)

^e Women's Center   (United States)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN;

ADULT; ARTICLE; ATHEROSCLEROSIS; AUTOPSY; BRAIN CELL; BRAIN VENTRICLE; CAUSE OF DEATH; CELL GROWTH; CELL SURVIVAL; CELL TRANSPLANTATION; CLINICAL ARTICLE; CLINICAL TRIAL; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; EMBRYO; FEASIBILITY STUDY; FEMALE; FETUS; FETUS CELL; HEADACHE; HEART ARRHYTHMIA; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; MALE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RATING SCALE; STEREOTAXIC SURGERY; SUBDURAL HEMATOMA; SURGICAL DRAINAGE; TREATMENT OUTCOME; VOMITING;

EID: 0037066096     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.58.5.687     Document Type: Article

References (45)

1. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
2. Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: A combined study using the section-Golgi method and calbindin D28k immunocytochemistry
3. Interference by huntingtin and atrophin-1 with CBP-mediated transcription leading to cellular toxicity
4. Rationale for intrastriatal grafting of striatal neuroblasts in patients with Huntington's disease
5. Neural transplantation for the treatment of Huntington's disease
6. Transplanted fetal striatum in Huntington's disease: Phenotypic development and lack of pathology
7. Functional neuronal replacement by grafted striatal neurons in the ibotenic acid-lesioned rat striatum
8. Anatomy and connectivity of intrastriatal striatal transplants
9. Characterization of GABA release from intrastriatal striatal transplants: Dependence on host-derived afferents
10. Cholecystokinin-dependent regulation of host dopamine inputs to striatal grafts
11. Reversal of long-term locomotor abnormalities in the kainic acid model of Huntington's disease by day 18 fetal striatal implants
12. Development of the human striatum: Implications for fetal striatal transplantation in the treatment of Huntington's disease
13. Transplantation of human fetal striatum into a rodent model of Huntington's disease ameliorates locomotor deficits
14. Human fetal striatal transplantation in an excitotoxic lesioned model of Huntington's disease
15. Behavioral effects of human striatal tissue derived from the far lateral ventricular eminence in a xenograft model of Huntington's disease
16. Transplantation of human fetal striatal tissue in Huntington's disease: Rationale for clinical studies
17. Intrastriatal transplantation of cross-species fetal striatal cells reduces abnormal movements in a primate model of Huntington's disease
18. Functional integration of striatal allografts in a primate model of Huntington's disease
19. Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease
20. Fetal nigral transplantation as a therapy for Parkinson's disease
21. Transplantation of embryonic dopamine neurons for severe Parkinson's disease
22. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
23. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease
24. Functional fetal nigral grafts in a patient with Parkinson's disease: Chemoanatomic, ultrastructural, and metabolic studies
25. Fetal grafting for Parkinson's disease: Expression of immune markers in two patients with functional fetal nigral grafts
26. Core assessment program for intracerebral transplantation in Huntington's disease (CAPIT-HD)
27. A new polymerase chain reaction (PCR) assay for the trinucleotide repeat that is unstable and expanded on Huntington's disease chromosomes
28. Unified Huntington's Disease Rating Scale: Reliability and consistency
29. Normalization for 3D PET with a low-scatter planar source and measured geometric factors
30. Bilateral fetal nigral transplantation into the postcommissural putamen in Parkinson's disease
31. Low-pressure abortion for obtaining embryonic and early gestational fetal tissue for research purposes
32. Motor and cognitive improvements in patients with Huntington's disease after neural transplantation
33. Infectious issues in human fetal neural transplantation
34. Distribution volume ratios without blood sampling from graphical analysis of PET data
35. Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18)2-fluoro-2-deoxy-D-glucose: Validation of method
36. Unified Huntington's Disease Rating Scale: A follow up
37. Rate of functional decline in Huntington's disease
38. Influence of lamotrigine on progression of early Huntington disease: A randomized clinical trial
39. Huntington's disease progression. PET and clinical observations
40. Neuropsychological functioning following fetal striatal transplantation in Huntington's chorea: Three case presentations
41. Safety of intrastriatal neurotransplantation for Huntington's disease patients
42. Neuropathological classification of Huntington's disease
43. Time course of the neuroprotective effect of transplantation on quinolinic acid-induced lesions of the striatum
44. Protection of the neostriatum against excitotoxic damage by neurotrophin-producing, genetically modified neural stem cells
45. Cellular delivery of trophic factors for the treatment of Huntington's disease: Is neuroprotection possible?