-
1
-
-
0036902881
-
Fetal striatal transplantation in Huntington's disease: time for a pause-the need to look at the rationale for fetal striatal transplantation
-
Albin R.L. Fetal striatal transplantation in Huntington's disease: time for a pause-the need to look at the rationale for fetal striatal transplantation. J. Neurol. Neurosurg. Psychiatr. 73 (2002) 612
-
(2002)
J. Neurol. Neurosurg. Psychiatr.
, vol.73
, pp. 612
-
-
Albin, R.L.1
-
2
-
-
0031907868
-
Uncertainty in xenotransplantation: individual benefit versus collective risk
-
Bach F.H., Fishman J.A., Daniels N., Proimos J., Anderson B., Carpenter C.B., Forrow L., Robson S.C., and Fineberg H.V. Uncertainty in xenotransplantation: individual benefit versus collective risk. Nat. Med. 4 (1998) 141-144
-
(1998)
Nat. Med.
, vol.4
, pp. 141-144
-
-
Bach, F.H.1
Fishman, J.A.2
Daniels, N.3
Proimos, J.4
Anderson, B.5
Carpenter, C.B.6
Forrow, L.7
Robson, S.C.8
Fineberg, H.V.9
-
3
-
-
0034009388
-
Safety and tolerability assessment of intrastriatal neural allografts in Huntington's disease patients
-
Bachoud-Lévi A.C., Bourdet C., Brugières P., Nguyen J.P., Grandmougin T., Haddad B., Jény R., Bartolomeo P., Boissé M.F., Dalla Barba G., Degos J.D., Ergis A.M., Lefaucheur J.P., Lisovoski F., Pailhous E., Rémy P., Palfi S., Defer G.L., Césaro P., Hantraye P., and Peschanski M. Safety and tolerability assessment of intrastriatal neural allografts in Huntington's disease patients. Exp. Neurol. 161 (2000) 194-202
-
(2000)
Exp. Neurol.
, vol.161
, pp. 194-202
-
-
Bachoud-Lévi, A.C.1
Bourdet, C.2
Brugières, P.3
Nguyen, J.P.4
Grandmougin, T.5
Haddad, B.6
Jény, R.7
Bartolomeo, P.8
Boissé, M.F.9
Dalla Barba, G.10
Degos, J.D.11
Ergis, A.M.12
Lefaucheur, J.P.13
Lisovoski, F.14
Pailhous, E.15
Rémy, P.16
Palfi, S.17
Defer, G.L.18
Césaro, P.19
Hantraye, P.20
Peschanski, M.21
more..
-
4
-
-
0034627143
-
Motor and cognitive improvements in patients with Huntington's disease after neural transplantation
-
Bachoud-Lévi A.C., Rémy P., Nguyen J.P., Brugières P., Lefaucheur J.P., Bourdet C., Baudic S., Gaura V., Maison P., Haddad B., Boissé M.F., Grandmougin T., Jény R., Bartolomeo P., Dalla Barba G., Degos J.D., Lisovski F., Ergis A.M., Pailhous E., Césaro P., Hantraye P., and Peschanski M. Motor and cognitive improvements in patients with Huntington's disease after neural transplantation. Lancet 356 (2000) 1975-1979
-
(2000)
Lancet
, vol.356
, pp. 1975-1979
-
-
Bachoud-Lévi, A.C.1
Rémy, P.2
Nguyen, J.P.3
Brugières, P.4
Lefaucheur, J.P.5
Bourdet, C.6
Baudic, S.7
Gaura, V.8
Maison, P.9
Haddad, B.10
Boissé, M.F.11
Grandmougin, T.12
Jény, R.13
Bartolomeo, P.14
Dalla Barba, G.15
Degos, J.D.16
Lisovski, F.17
Ergis, A.M.18
Pailhous, E.19
Césaro, P.20
Hantraye, P.21
Peschanski, M.22
more..
-
5
-
-
0038701684
-
Huntingtin aggregation and toxicity in Huntington's disease
-
Bates G. Huntingtin aggregation and toxicity in Huntington's disease. Lancet 361 (2003) 1642-1644
-
(2003)
Lancet
, vol.361
, pp. 1642-1644
-
-
Bates, G.1
-
6
-
-
2342598416
-
Experimental therapeutics in transgenic mouse models of Huntington's disease
-
Beal M.F., and Ferrante R.J. Experimental therapeutics in transgenic mouse models of Huntington's disease. Nat. Rev. Neurosci. 5 (2004) 373-384
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, pp. 373-384
-
-
Beal, M.F.1
Ferrante, R.J.2
-
7
-
-
18344417278
-
Neural transplantation for the treatment of Parkinson's disease
-
Björklund A., Dunnett S.B., Brundin P., Stoessl A.J., Freed C.R., Breeze R.E., Levivier M., Peschanski M., Studer L., and Barker R. Neural transplantation for the treatment of Parkinson's disease. Lancet Neurol. 2 (2003) 437-445
-
(2003)
Lancet Neurol.
, vol.2
, pp. 437-445
-
-
Björklund, A.1
Dunnett, S.B.2
Brundin, P.3
Stoessl, A.J.4
Freed, C.R.5
Breeze, R.E.6
Levivier, M.7
Peschanski, M.8
Studer, L.9
Barker, R.10
-
8
-
-
0034032642
-
Cell replacement therapies for central nervous system disorders
-
Björklund A., and Lindvall O. Cell replacement therapies for central nervous system disorders. Nat. Neurosci. 3 (2000) 537-544
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 537-544
-
-
Björklund, A.1
Lindvall, O.2
-
9
-
-
0028104614
-
Ethical guidelines for the use of human embryonic or fetal tissue for experimental and clinical neurotransplantation and research
-
Boer G.J. Ethical guidelines for the use of human embryonic or fetal tissue for experimental and clinical neurotransplantation and research. J. Neurol. 242 (1994) 1-13
-
(1994)
J. Neurol.
, vol.242
, pp. 1-13
-
-
Boer, G.J.1
-
10
-
-
0037201104
-
Clinical neurotransplantation: core assessment protocol rather than sham surgery as control
-
Boer G.J., and Widner H. Clinical neurotransplantation: core assessment protocol rather than sham surgery as control. Brain Res. Bull. 58 (2002) 547-553
-
(2002)
Brain Res. Bull.
, vol.58
, pp. 547-553
-
-
Boer, G.J.1
Widner, H.2
-
11
-
-
0028856643
-
Asymmetrical behavior in rats following striatal lesions and fetal transplants: the elevated body swing test
-
Borlongan C.V., Cahill D.W., and Sanberg P.R. Asymmetrical behavior in rats following striatal lesions and fetal transplants: the elevated body swing test. Rest. Neurol. Neurosci. 9 (1995) 15-19
-
(1995)
Rest. Neurol. Neurosci.
, vol.9
, pp. 15-19
-
-
Borlongan, C.V.1
Cahill, D.W.2
Sanberg, P.R.3
-
12
-
-
0024992960
-
Angiogenesis and the blood-brain barrier in solid and dissociated cell grafts within the CNS
-
Broadwell R.D., Charlton H.M., Ebert P., Hickey W.F., Villegas J.C., and Wolf A.L. Angiogenesis and the blood-brain barrier in solid and dissociated cell grafts within the CNS. Prog. Brain Res. 82 (1990) 95-101
-
(1990)
Prog. Brain Res.
, vol.82
, pp. 95-101
-
-
Broadwell, R.D.1
Charlton, H.M.2
Ebert, P.3
Hickey, W.F.4
Villegas, J.C.5
Wolf, A.L.6
-
14
-
-
0030028145
-
Paucity of P-zones in striatal grafts prohibit commencement of clinical trials in Huntington's disease
-
Brundin P., Fricker R.A., and Nakao N. Paucity of P-zones in striatal grafts prohibit commencement of clinical trials in Huntington's disease. Neuroscience 71 (1996) 895-897
-
(1996)
Neuroscience
, vol.71
, pp. 895-897
-
-
Brundin, P.1
Fricker, R.A.2
Nakao, N.3
-
15
-
-
0141987860
-
The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg
-
Ciechanover A., and Brundin P. The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg. Neuron 40 (2003) 427-446
-
(2003)
Neuron
, vol.40
, pp. 427-446
-
-
Ciechanover, A.1
Brundin, P.2
-
16
-
-
0017167057
-
Lesions of striatal neurones with kainic acid provides a model for Huntington's chorea
-
Coyle J.T., and Schwarcz R. Lesions of striatal neurones with kainic acid provides a model for Huntington's chorea. Nature 263 (1976) 244-246
-
(1976)
Nature
, vol.263
, pp. 244-246
-
-
Coyle, J.T.1
Schwarcz, R.2
-
17
-
-
16944366484
-
Histological evidence of fetal pig neural cell survival after transplantation into a patient with Parkinson's disease
-
Deacon T., Schumacher J., Dinsmore J., Thomas C., Palmer P., Kott S., Edge A., Penney D., Kassissieh S., Dempsey P., and Isacson O. Histological evidence of fetal pig neural cell survival after transplantation into a patient with Parkinson's disease. Nat. Med. 3 (1997) 350-353
-
(1997)
Nat. Med.
, vol.3
, pp. 350-353
-
-
Deacon, T.1
Schumacher, J.2
Dinsmore, J.3
Thomas, C.4
Palmer, P.5
Kott, S.6
Edge, A.7
Penney, D.8
Kassissieh, S.9
Dempsey, P.10
Isacson, O.11
-
18
-
-
0028585837
-
The lateral ganglionic eminence is the origin of cells committed to striatal phenotypes: neural transplantation and developmental evidence
-
Deacon T.W., Pakzaban P., and Isacson O. The lateral ganglionic eminence is the origin of cells committed to striatal phenotypes: neural transplantation and developmental evidence. Brain Res. 668 (1994) 211-219
-
(1994)
Brain Res.
, vol.668
, pp. 211-219
-
-
Deacon, T.W.1
Pakzaban, P.2
Isacson, O.3
-
19
-
-
0033428823
-
Core assessment program for surgical interventional therapies in Parkinson's disease (CAPSIT-PD)
-
Defer G.L., Widner H., Marié R.M., Rémy P., and Levivier M. Core assessment program for surgical interventional therapies in Parkinson's disease (CAPSIT-PD). Mov. Disord. 14 (1999) 572-584
-
(1999)
Mov. Disord.
, vol.14
, pp. 572-584
-
-
Defer, G.L.1
Widner, H.2
Marié, R.M.3
Rémy, P.4
Levivier, M.5
-
20
-
-
0028872929
-
Functional repair of striatal systems by neural transplants: evidence for circuit reconstruction
-
Dunnett S.B. Functional repair of striatal systems by neural transplants: evidence for circuit reconstruction. Behav. Brain Res. 66 (1995) 133-142
-
(1995)
Behav. Brain Res.
, vol.66
, pp. 133-142
-
-
Dunnett, S.B.1
-
22
-
-
0032211289
-
Striatal transplantation in a transgenic mouse model of Huntington's disease
-
Dunnett S.B., Carter R.J., Watts C., Torres E.M., Mahal A., Mangiarini L., Bates G., and Morton A.J. Striatal transplantation in a transgenic mouse model of Huntington's disease. Exp. Neurol. 154 (1998) 31-40
-
(1998)
Exp. Neurol.
, vol.154
, pp. 31-40
-
-
Dunnett, S.B.1
Carter, R.J.2
Watts, C.3
Torres, E.M.4
Mahal, A.5
Mangiarini, L.6
Bates, G.7
Morton, A.J.8
-
23
-
-
26244445193
-
Frontal-striatal disconnection disrupts cognitive performance of the frontal-type in the rat
-
Dunnett S.B., Meldrum A., and Muir J.L. Frontal-striatal disconnection disrupts cognitive performance of the frontal-type in the rat. Neuroscience 155 (2005) 1055-1065
-
(2005)
Neuroscience
, vol.155
, pp. 1055-1065
-
-
Dunnett, S.B.1
Meldrum, A.2
Muir, J.L.3
-
25
-
-
15444378095
-
Cell therapy in Huntington's disease
-
Dunnett S.B., and Rosser A.E. Cell therapy in Huntington's disease. NeuroRx 1 (2004) 394-405
-
(2004)
NeuroRx
, vol.1
, pp. 394-405
-
-
Dunnett, S.B.1
Rosser, A.E.2
-
26
-
-
33745261233
-
Striatal grafts alleviate bilateral striatal lesion deficits in operant delayed alternation in the rat
-
Dunnett S.B., White A., Heath J., Torres E.M., and Gates R.A. Striatal grafts alleviate bilateral striatal lesion deficits in operant delayed alternation in the rat. Exp. Neurol. 199 (2006) 478-489
-
(2006)
Exp. Neurol.
, vol.199
, pp. 478-489
-
-
Dunnett, S.B.1
White, A.2
Heath, J.3
Torres, E.M.4
Gates, R.A.5
-
27
-
-
33847619878
-
-
European Parliament and Council, Directive 2004/23/EC of 31 March 2004, on setting standards of quality and safety for the donation, procurement, testing, processing, preservation, storage and distribution of human tissues and cells. Off. J. Eur. Union L102 (2004) 48-58.
-
-
-
-
28
-
-
33746708104
-
Neural transplantation in Huntington's disease: NEST-UK donor tissue microbiological screening programme and review of the literature
-
Farrington M., Wreghitt T.G., Lever A.M., Dunnett S.B., Rosser A.E., and Barker R.A. Neural transplantation in Huntington's disease: NEST-UK donor tissue microbiological screening programme and review of the literature. Cell Transplant. 15 (2006) 279-289
-
(2006)
Cell Transplant.
, vol.15
, pp. 279-289
-
-
Farrington, M.1
Wreghitt, T.G.2
Lever, A.M.3
Dunnett, S.B.4
Rosser, A.E.5
Barker, R.A.6
-
30
-
-
0034105443
-
Porcine xenografts in Parkinson's disease and Huntington's disease patients: preliminary results
-
Fink J.S., Schumacher J.M., Ellias S.A., Palmer E.P., Saint-Hilaire M., Shannon K., Penn R., Starr P., Van Horne C., Kott H.S., Dempsey P.K., Fischman A.J., Raineri R., Manhart C., Dinsmore J., and Isacson O. Porcine xenografts in Parkinson's disease and Huntington's disease patients: preliminary results. Cell Transplant. 9 (2000) 273-278
-
(2000)
Cell Transplant.
, vol.9
, pp. 273-278
-
-
Fink, J.S.1
Schumacher, J.M.2
Ellias, S.A.3
Palmer, E.P.4
Saint-Hilaire, M.5
Shannon, K.6
Penn, R.7
Starr, P.8
Van Horne, C.9
Kott, H.S.10
Dempsey, P.K.11
Fischman, A.J.12
Raineri, R.13
Manhart, C.14
Dinsmore, J.15
Isacson, O.16
-
31
-
-
0029895301
-
Survival and proliferation of non-neural tissues, with obstruction of cerebral ventricles, in a Parkinsonian patient treated with fetal allografts
-
Folkerth R.D., and Durso R. Survival and proliferation of non-neural tissues, with obstruction of cerebral ventricles, in a Parkinsonian patient treated with fetal allografts. Neurology 46 (1996) 1219-1225
-
(1996)
Neurology
, vol.46
, pp. 1219-1225
-
-
Folkerth, R.D.1
Durso, R.2
-
32
-
-
12944288307
-
Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology
-
Freeman T.B., Cicchetti F., Hauser R.A., Deacon T.W., Li X.J., Hersch S.M., Nauert G.M., Sanberg P.R., Kordower J.H., Saporta S., and Isacson O. Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 13877-13882
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13877-13882
-
-
Freeman, T.B.1
Cicchetti, F.2
Hauser, R.A.3
Deacon, T.W.4
Li, X.J.5
Hersch, S.M.6
Nauert, G.M.7
Sanberg, P.R.8
Kordower, J.H.9
Saporta, S.10
Isacson, O.11
-
33
-
-
0033598429
-
Use of placebo surgery in controlled trials of a cellular-based therapy for Parkinson's disease
-
Freeman T.B., Vawter D.E., Leaverton P.E., Godbold J.H., Hauser R.A., Goetz C.G., and Olanow C.W. Use of placebo surgery in controlled trials of a cellular-based therapy for Parkinson's disease. N. Engl. J. Med. 341 (1999) 988-992
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 988-992
-
-
Freeman, T.B.1
Vawter, D.E.2
Leaverton, P.E.3
Godbold, J.H.4
Hauser, R.A.5
Goetz, C.G.6
Olanow, C.W.7
-
34
-
-
0030754874
-
The effects of donor stage on the survival and function of embryonic striatal grafts. II: Correlation between positron emission tomography and reaching behaviour
-
Fricker R.A., Torres E.M., Hume S.P., Myers R., Opacka-Juffry J., Ashworth S., and Dunnett S.B. The effects of donor stage on the survival and function of embryonic striatal grafts. II: Correlation between positron emission tomography and reaching behaviour. Neuroscience 79 (1997) 711-722
-
(1997)
Neuroscience
, vol.79
, pp. 711-722
-
-
Fricker, R.A.1
Torres, E.M.2
Hume, S.P.3
Myers, R.4
Opacka-Juffry, J.5
Ashworth, S.6
Dunnett, S.B.7
-
35
-
-
23244461696
-
Positron emission tomography after fetal transplantation in Huntington's disease
-
Furtado S., Sossi V., Hauser R.A., Samii A., Schulzer M., Murphy C.B., Freeman T.B., and Stoessl A.J. Positron emission tomography after fetal transplantation in Huntington's disease. Ann. Neurol. 58 (2005) 331-337
-
(2005)
Ann. Neurol.
, vol.58
, pp. 331-337
-
-
Furtado, S.1
Sossi, V.2
Hauser, R.A.3
Samii, A.4
Schulzer, M.5
Murphy, C.B.6
Freeman, T.B.7
Stoessl, A.J.8
-
36
-
-
9144221004
-
Striatal neural grafting improves cortical metabolism in Huntington's disease patients
-
Gaura V., Bachoud-Lévi A.C., Ribeiro M.J., Nguyen J.P., Frouin V., Baudic S., Brugières P., Mangin J.F., Boissé M.F., Palfi S., Césaro P., Samson Y., Hantraye P., Peschanski M., and Rémy P. Striatal neural grafting improves cortical metabolism in Huntington's disease patients. Brain 127 (2004) 65-72
-
(2004)
Brain
, vol.127
, pp. 65-72
-
-
Gaura, V.1
Bachoud-Lévi, A.C.2
Ribeiro, M.J.3
Nguyen, J.P.4
Frouin, V.5
Baudic, S.6
Brugières, P.7
Mangin, J.F.8
Boissé, M.F.9
Palfi, S.10
Césaro, P.11
Samson, Y.12
Hantraye, P.13
Peschanski, M.14
Rémy, P.15
-
37
-
-
0041334004
-
[11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy
-
Gerhard A., Banati R.B., Goerres G.B., Cagnin A., Myers R., Gunn R.N., Turkheimer F., Good C.D., Mathias C.J., Quinn N., Schwarz J., and Brooks D.J. [11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy. Neurology 61 (2003) 686-689
-
(2003)
Neurology
, vol.61
, pp. 686-689
-
-
Gerhard, A.1
Banati, R.B.2
Goerres, G.B.3
Cagnin, A.4
Myers, R.5
Gunn, R.N.6
Turkheimer, F.7
Good, C.D.8
Mathias, C.J.9
Quinn, N.10
Schwarz, J.11
Brooks, D.J.12
-
38
-
-
0029993991
-
Phenotypic development of the human embryonic striatal primordium: a study of cultured and grafted neurons from the lateral and medial ganglionic eminence
-
Grasbon-Frodl E.M., Nakao N., Lindvall O., and Brundin P. Phenotypic development of the human embryonic striatal primordium: a study of cultured and grafted neurons from the lateral and medial ganglionic eminence. Neuroscience 73 (1996) 171-183
-
(1996)
Neuroscience
, vol.73
, pp. 171-183
-
-
Grasbon-Frodl, E.M.1
Nakao, N.2
Lindvall, O.3
Brundin, P.4
-
39
-
-
0030932167
-
Developmental features of human striatal tissue transplanted in a rat model of Huntington's disease
-
Grasbon-Frodl E.M., Nakao N., Lindvall O., and Brundin P. Developmental features of human striatal tissue transplanted in a rat model of Huntington's disease. Neurobiol. Dis. 3 (1997) 299-311
-
(1997)
Neurobiol. Dis.
, vol.3
, pp. 299-311
-
-
Grasbon-Frodl, E.M.1
Nakao, N.2
Lindvall, O.3
Brundin, P.4
-
40
-
-
0024439946
-
Intrastriatal grafts derived from fetal striatal primordia. 1: Phenotypy and modular organization
-
Graybiel A.M., Liu F.C., and Dunnett S.B. Intrastriatal grafts derived from fetal striatal primordia. 1: Phenotypy and modular organization. J. Neurosci. 9 (1989) 3250-3271
-
(1989)
J. Neurosci.
, vol.9
, pp. 3250-3271
-
-
Graybiel, A.M.1
Liu, F.C.2
Dunnett, S.B.3
-
41
-
-
0037066135
-
We need something better and we need it now-fetal striatal transplantation in Huntington's disease?
-
Greenamyre J.T., and Shoulson I. We need something better and we need it now-fetal striatal transplantation in Huntington's disease?. Neurology 58 (2002) 675-676
-
(2002)
Neurology
, vol.58
, pp. 675-676
-
-
Greenamyre, J.T.1
Shoulson, I.2
-
42
-
-
0032692348
-
Sequential bilateral transplantation in Parkinson's disease-effects of the second graft
-
Hagell P., Schrag A., Piccini P., Jahanshahi M., Brown R., Rehncrona S., Widner H., Brundin P., Rothwell J.C., Odin P., Wenning G.K., Morrish P., Gustavii B., Björklund A., Brooks D.J., Marsden C.D., Quinn N.P., and Lindvall O. Sequential bilateral transplantation in Parkinson's disease-effects of the second graft. Brain 122 (1999) 1121-1132
-
(1999)
Brain
, vol.122
, pp. 1121-1132
-
-
Hagell, P.1
Schrag, A.2
Piccini, P.3
Jahanshahi, M.4
Brown, R.5
Rehncrona, S.6
Widner, H.7
Brundin, P.8
Rothwell, J.C.9
Odin, P.10
Wenning, G.K.11
Morrish, P.12
Gustavii, B.13
Björklund, A.14
Brooks, D.J.15
Marsden, C.D.16
Quinn, N.P.17
Lindvall, O.18
-
43
-
-
0033053030
-
Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease
-
Hauser R.A., Freeman T.B., Snow B.J., Nauert M., Gauger L., Kordower J.H., and Olanow C.W. Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease. Arch. Neurol. 56 (1999) 179-187
-
(1999)
Arch. Neurol.
, vol.56
, pp. 179-187
-
-
Hauser, R.A.1
Freeman, T.B.2
Snow, B.J.3
Nauert, M.4
Gauger, L.5
Kordower, J.H.6
Olanow, C.W.7
-
44
-
-
0037066096
-
Bilateral human fetal striatal transplantation in Huntington's disease
-
Hauser R.A., Furtado S., Cimino C.R., Delgado H., Eichler S., Schwartz S., Scott D., Nauert G.M., Soety E., Sossi V., Holt D.A., Sanberg P.R., Stoessl A.J., and Freeman T.B. Bilateral human fetal striatal transplantation in Huntington's disease. Neurology 58 (2002) 687-695
-
(2002)
Neurology
, vol.58
, pp. 687-695
-
-
Hauser, R.A.1
Furtado, S.2
Cimino, C.R.3
Delgado, H.4
Eichler, S.5
Schwartz, S.6
Scott, D.7
Nauert, G.M.8
Soety, E.9
Sossi, V.10
Holt, D.A.11
Sanberg, P.R.12
Stoessl, A.J.13
Freeman, T.B.14
-
45
-
-
0037066096
-
Bilateral human fetal striatal transplantation in Huntington's disease
-
Hauser R.A., Sandberg P.R., Freeman T.B., and Stoessl A.J. Bilateral human fetal striatal transplantation in Huntington's disease. Neurology 58 (2002) 1704
-
(2002)
Neurology
, vol.58
, pp. 1704
-
-
Hauser, R.A.1
Sandberg, P.R.2
Freeman, T.B.3
Stoessl, A.J.4
-
46
-
-
0037376680
-
Apoptosis in Huntington's disease
-
Hickey M.A., and Chesselet M.F. Apoptosis in Huntington's disease. Prog. Neurol. 27 (2003) 255-265
-
(2003)
Prog. Neurol.
, vol.27
, pp. 255-265
-
-
Hickey, M.A.1
Chesselet, M.F.2
-
47
-
-
0031900412
-
Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases
-
Hoang T.Q., Bluml S., Dubowitz D.J., Moats R., Kopyov O., Jacques D., and Ross B.D. Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases. Neurology 50 (1998) 1033-1040
-
(1998)
Neurology
, vol.50
, pp. 1033-1040
-
-
Hoang, T.Q.1
Bluml, S.2
Dubowitz, D.J.3
Moats, R.4
Kopyov, O.5
Jacques, D.6
Ross, B.D.7
-
48
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group
-
Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72 (1993) 971-983
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
49
-
-
0242407061
-
Long-term hibernation of human fetal striatal tissue does not adversely affect its differentiation in vitro or graft survival: implications for clinical trials in Huntington's disease
-
Hurelbrink C.B., Tyers P., Armstrong R.J.E., Dunnett S.B., Barker R.A., and Rosser A.E. Long-term hibernation of human fetal striatal tissue does not adversely affect its differentiation in vitro or graft survival: implications for clinical trials in Huntington's disease. Cell Transplant. 12 (2003) 687-695
-
(2003)
Cell Transplant.
, vol.12
, pp. 687-695
-
-
Hurelbrink, C.B.1
Tyers, P.2
Armstrong, R.J.E.3
Dunnett, S.B.4
Barker, R.A.5
Rosser, A.E.6
-
50
-
-
0021226160
-
Functional neuronal replacement by grafted striatal neurons in the ibotenic acid lesioned rat striatum
-
Isacson O., Brundin P., Kelly P.A.T., Gage F.H., and Björklund A. Functional neuronal replacement by grafted striatal neurons in the ibotenic acid lesioned rat striatum. Nature 311 (1984) 458-460
-
(1984)
Nature
, vol.311
, pp. 458-460
-
-
Isacson, O.1
Brundin, P.2
Kelly, P.A.T.3
Gage, F.H.4
Björklund, A.5
-
51
-
-
33847625558
-
Neuronal cells for transplantation in Huntington's disease
-
Davis-Sanberg C., and Sanberg P.R. (Eds), Humana Press, Totowa
-
Kelly C.M., Rosser A.E., and Dunnett S.B. Neuronal cells for transplantation in Huntington's disease. In: Davis-Sanberg C., and Sanberg P.R. (Eds). Cell Therapy for Brain Repair (2006), Humana Press, Totowa 83-115
-
(2006)
Cell Therapy for Brain Repair
, pp. 83-115
-
-
Kelly, C.M.1
Rosser, A.E.2
Dunnett, S.B.3
-
52
-
-
0003109937
-
In vivo PET analysis of the status of striatal allografts in the common marmoset
-
Kendall A.L., Rayment D., Aigbirhio F., Baker H.F., Chandler R., Clark J., Dettman C., Dunnett S.B., Jeavons A., Page K., Ridley R.M., Torres E.M., Turkheimer F., and Visvikis D. In vivo PET analysis of the status of striatal allografts in the common marmoset. Eur. J. Neurosci. 10 Suppl. (1999) 370
-
(1999)
Eur. J. Neurosci.
, vol.10
, Issue.SUPPL
, pp. 370
-
-
Kendall, A.L.1
Rayment, D.2
Aigbirhio, F.3
Baker, H.F.4
Chandler, R.5
Clark, J.6
Dettman, C.7
Dunnett, S.B.8
Jeavons, A.9
Page, K.10
Ridley, R.M.11
Torres, E.M.12
Turkheimer, F.13
Visvikis, D.14
-
53
-
-
0031777250
-
Functional integration of striatal allografts in a primate model of Huntington's disease
-
Kendall A.L., Rayment F.D., Torres E.M., Baker H.F., Ridley R.M., and Dunnett S.B. Functional integration of striatal allografts in a primate model of Huntington's disease. Nat. Med. 4 (1998) 727-729
-
(1998)
Nat. Med.
, vol.4
, pp. 727-729
-
-
Kendall, A.L.1
Rayment, F.D.2
Torres, E.M.3
Baker, H.F.4
Ridley, R.M.5
Dunnett, S.B.6
-
54
-
-
21944446706
-
Histological analysis of fetal dopamine cell suspension grafts in two patients with Parkinson's disease gives promising results
-
Kirik D., and Björklund A. Histological analysis of fetal dopamine cell suspension grafts in two patients with Parkinson's disease gives promising results. Brain 128 (2005) 1478-1479
-
(2005)
Brain
, vol.128
, pp. 1478-1479
-
-
Kirik, D.1
Björklund, A.2
-
55
-
-
0002716115
-
Fetal transplantation for Huntington's disease: clinical studies
-
Freeman T.B., and Kordower J.H. (Eds), Humana Press, Totowa, NJ
-
Kopyov O.V., Jacques S., Kurth M., Philpott L.M., Lee A., Patterson M., Duma C., Lieberman A., and Eagle K.S. Fetal transplantation for Huntington's disease: clinical studies. In: Freeman T.B., and Kordower J.H. (Eds). Cell Transplantation for Neurological Disorders (1998), Humana Press, Totowa, NJ 95-134
-
(1998)
Cell Transplantation for Neurological Disorders
, pp. 95-134
-
-
Kopyov, O.V.1
Jacques, S.2
Kurth, M.3
Philpott, L.M.4
Lee, A.5
Patterson, M.6
Duma, C.7
Lieberman, A.8
Eagle, K.S.9
-
56
-
-
0031887047
-
Safety of intrastriatal neurotransplantation for Huntington's disease patients
-
Kopyov O.V., Jacques S., Lieberman A., Duma C.M., and Eagle K.S. Safety of intrastriatal neurotransplantation for Huntington's disease patients. Exp. Neurol. 119 (1998) 97-108
-
(1998)
Exp. Neurol.
, vol.119
, pp. 97-108
-
-
Kopyov, O.V.1
Jacques, S.2
Lieberman, A.3
Duma, C.M.4
Eagle, K.S.5
-
57
-
-
0031106244
-
Dopaminergic transplants in patients with Parkinson's disease: neuroanatomical correlates of clinical recovery
-
Kordower J.H., Goetz C.G., Freeman T.B., and Olanow C.W. Dopaminergic transplants in patients with Parkinson's disease: neuroanatomical correlates of clinical recovery. Exp. Neurol. 144 (1997) 41-46
-
(1997)
Exp. Neurol.
, vol.144
, pp. 41-46
-
-
Kordower, J.H.1
Goetz, C.G.2
Freeman, T.B.3
Olanow, C.W.4
-
58
-
-
33847671486
-
Improvement in motor function after fetal transplantation in a patient with Huntington's disease
-
Kurth M.C., Kopyov O., and Jacques D.B. Improvement in motor function after fetal transplantation in a patient with Huntington's disease. Neurology 46 (1996) 22006
-
(1996)
Neurology
, vol.46
, pp. 22006
-
-
Kurth, M.C.1
Kopyov, O.2
Jacques, D.B.3
-
59
-
-
0026515731
-
Core assessment program for intracerebral transplantation (CAPIT)
-
Langston J.W., Widner H., and Goetz C.G. Core assessment program for intracerebral transplantation (CAPIT). Mov. Disord. 7 (1992) 2-13
-
(1992)
Mov. Disord.
, vol.7
, pp. 2-13
-
-
Langston, J.W.1
Widner, H.2
Goetz, C.G.3
-
60
-
-
0027957150
-
Vascularization and microvascular permeability in solid versus cell-suspension embryonic neural grafts
-
Leigh K., Elisevich K., and Rogers K.A. Vascularization and microvascular permeability in solid versus cell-suspension embryonic neural grafts. J. Neurosurg. 81 (1994) 272-283
-
(1994)
J. Neurosurg.
, vol.81
, pp. 272-283
-
-
Leigh, K.1
Elisevich, K.2
Rogers, K.A.3
-
61
-
-
0034589755
-
Clinical observations after neural transplantation in Parkinson's disease
-
Lindvall O., and Hagell P. Clinical observations after neural transplantation in Parkinson's disease. Prog. Brain Res. 127 (2000) 299-320
-
(2000)
Prog. Brain Res.
, vol.127
, pp. 299-320
-
-
Lindvall, O.1
Hagell, P.2
-
62
-
-
0029122537
-
Fetal striatal homotransplantation for Huntington's disease: first two case reports
-
Madrazo I., Franco-Bourland R.E., Castrejon H., Cuevas C., and Ostrosky-Solis F. Fetal striatal homotransplantation for Huntington's disease: first two case reports. Neurol. Res. 17 (1995) 312-315
-
(1995)
Neurol. Res.
, vol.17
, pp. 312-315
-
-
Madrazo, I.1
Franco-Bourland, R.E.2
Castrejon, H.3
Cuevas, C.4
Ostrosky-Solis, F.5
-
63
-
-
0031656675
-
Fatal cyst formation after fetal mesencephalic allograft transplant for Parkinson's disease
-
Mamelak A.N., Eggerding F.A., Oh D.S., Wilson E., Davis R.L., Spitzer R., Hay J.A., and Caton III W.L. Fatal cyst formation after fetal mesencephalic allograft transplant for Parkinson's disease. J. Neurosurg. 89 (1998) 592-598
-
(1998)
J. Neurosurg.
, vol.89
, pp. 592-598
-
-
Mamelak, A.N.1
Eggerding, F.A.2
Oh, D.S.3
Wilson, E.4
Davis, R.L.5
Spitzer, R.6
Hay, J.A.7
Caton III, W.L.8
-
64
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L., Sathasivam K., Seller M., Cozens B., Harper A., Hetherington C., Lawton M., Trottier Y., Lehrach H., Davies S.W., and Bates G.P. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 87 (1996) 493-506
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
65
-
-
33846450521
-
Synaptic plasticity in striatal grafts
-
Bolam J.P., Ingham C.A., and Magill P.J. (Eds), Springer, New York
-
Mazzocchi-Jones D., Döbrössy M.D., and Dunnett S.B. Synaptic plasticity in striatal grafts. In: Bolam J.P., Ingham C.A., and Magill P.J. (Eds). The Basal Ganglia VIII (2005), Springer, New York 313-320
-
(2005)
The Basal Ganglia VIII
, pp. 313-320
-
-
Mazzocchi-Jones, D.1
Döbrössy, M.D.2
Dunnett, S.B.3
-
66
-
-
33847642918
-
-
Medical Research Council, Guidelines for Good Clinical Practice, Medical Research Council, London, 1998.
-
-
-
-
68
-
-
0029778165
-
The public health risk of animal organ and tissue transplantation into humans
-
Murphy F.A. The public health risk of animal organ and tissue transplantation into humans. Science 273 (1996) 746-747
-
(1996)
Science
, vol.273
, pp. 746-747
-
-
Murphy, F.A.1
-
69
-
-
0030045705
-
Ontogeny of human striatal DARPP-32 neurons in fetuses and following xenografting to the adult rat brain
-
Naimi S., Jény R., Hantraye P., Peschanski M., and Riche D. Ontogeny of human striatal DARPP-32 neurons in fetuses and following xenografting to the adult rat brain. Exp. Neurol. 137 (1996) 15-25
-
(1996)
Exp. Neurol.
, vol.137
, pp. 15-25
-
-
Naimi, S.1
Jény, R.2
Hantraye, P.3
Peschanski, M.4
Riche, D.5
-
70
-
-
0032890301
-
Embryonic striatal grafts restore neuronal activity of the globus pallidus in a rodent model of Huntington's disease
-
Nakao N., Ogura M., Nakai K., and Itakura T. Embryonic striatal grafts restore neuronal activity of the globus pallidus in a rodent model of Huntington's disease. Neuroscience 88 (1999) 469-477
-
(1999)
Neuroscience
, vol.88
, pp. 469-477
-
-
Nakao, N.1
Ogura, M.2
Nakai, K.3
Itakura, T.4
-
71
-
-
0028084486
-
Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat Parkinson model
-
Nikkhah G., Cunningham M.G., Jödicke A., Knappe U., and Björklund A. Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat Parkinson model. Brain Res. 633 (1994) 133-143
-
(1994)
Brain Res.
, vol.633
, pp. 133-143
-
-
Nikkhah, G.1
Cunningham, M.G.2
Jödicke, A.3
Knappe, U.4
Björklund, A.5
-
72
-
-
0027204258
-
Striatal grafts in the ischemic striatum improve pallidal GABA release and passive avoidance
-
Nishino H., Koide K., Aihara N., Kumazaki M., Sakurai T., and Nagai H. Striatal grafts in the ischemic striatum improve pallidal GABA release and passive avoidance. Brain Res. Bull. 32 (1993) 517-520
-
(1993)
Brain Res. Bull.
, vol.32
, pp. 517-520
-
-
Nishino, H.1
Koide, K.2
Aihara, N.3
Kumazaki, M.4
Sakurai, T.5
Nagai, H.6
-
73
-
-
0032562172
-
Early specification of striatal projection neurons and interneuronal subtypes in the lateral and medial ganglionic eminence
-
Olsson M., Björklund A., and Campbell K. Early specification of striatal projection neurons and interneuronal subtypes in the lateral and medial ganglionic eminence. Neuroscience 84 (1998) 867-876
-
(1998)
Neuroscience
, vol.84
, pp. 867-876
-
-
Olsson, M.1
Björklund, A.2
Campbell, K.3
-
74
-
-
0028884523
-
Projection neurons in fetal striatal transplants are predominantly derived from the lateral ganglionic eminence
-
Olsson M., Campbell K., Wictorin K., and Björklund A. Projection neurons in fetal striatal transplants are predominantly derived from the lateral ganglionic eminence. Neuroscience 69 (1995) 1169-1182
-
(1995)
Neuroscience
, vol.69
, pp. 1169-1182
-
-
Olsson, M.1
Campbell, K.2
Wictorin, K.3
Björklund, A.4
-
75
-
-
0031724818
-
Endogenous retroviruses and the safety of porcine xenotransplantation
-
Onions D., Hart D., Mahoney C., Galbraith D., and Smith K. Endogenous retroviruses and the safety of porcine xenotransplantation. Trends Microbiol. 6 (1998) 430-431
-
(1998)
Trends Microbiol.
, vol.6
, pp. 430-431
-
-
Onions, D.1
Hart, D.2
Mahoney, C.3
Galbraith, D.4
Smith, K.5
-
76
-
-
0028952138
-
A novel mode of immunoprotection of neural xenotransplants: masking of donor major histocompatibility complex class I enhances transplant survival in the central nervous system
-
Pakzaban P., Deacon T.W., Burns L.H., Dinsmore J., and Isacson O. A novel mode of immunoprotection of neural xenotransplants: masking of donor major histocompatibility complex class I enhances transplant survival in the central nervous system. Neuroscience 65 (1995) 983-996
-
(1995)
Neuroscience
, vol.65
, pp. 983-996
-
-
Pakzaban, P.1
Deacon, T.W.2
Burns, L.H.3
Dinsmore, J.4
Isacson, O.5
-
77
-
-
0027724863
-
Increased proportion of acetylcholinesterase-rich zones and improved morphological integration in host striatum of fetal grafts derived from the lateral but not the medial ganglionic eminence
-
Pakzaban P., Deacon T.W., Burns L.H., and Isacson O. Increased proportion of acetylcholinesterase-rich zones and improved morphological integration in host striatum of fetal grafts derived from the lateral but not the medial ganglionic eminence. Exp. Brain Res. 97 (1993) 13-22
-
(1993)
Exp. Brain Res.
, vol.97
, pp. 13-22
-
-
Pakzaban, P.1
Deacon, T.W.2
Burns, L.H.3
Isacson, O.4
-
78
-
-
0031902287
-
Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington's disease
-
Palfi S., Condé F., Riche D., Brouillet E., Dautry C., Mittoux V., Hantraye P., and Peschanski M. Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington's disease. Nat. Med. 4 (1998) 963-966
-
(1998)
Nat. Med.
, vol.4
, pp. 963-966
-
-
Palfi, S.1
Condé, F.2
Riche, D.3
Brouillet, E.4
Dautry, C.5
Mittoux, V.6
Hantraye, P.7
Peschanski, M.8
-
79
-
-
0032051771
-
MRI-stereotactical approach for neural grafting in basal ganglia disorders
-
Palfi S., Nguyen J.P., Brugières P., LeGuerinel C., Hantraye P., Rémy P., Rostaing S., Defer G.L., Césaro P., Keravel Y., and Peschanski M. MRI-stereotactical approach for neural grafting in basal ganglia disorders. Exp. Neurol. 150 (1998) 272-281
-
(1998)
Exp. Neurol.
, vol.150
, pp. 272-281
-
-
Palfi, S.1
Nguyen, J.P.2
Brugières, P.3
LeGuerinel, C.4
Hantraye, P.5
Rémy, P.6
Rostaing, S.7
Defer, G.L.8
Césaro, P.9
Keravel, Y.10
Peschanski, M.11
-
80
-
-
0037408213
-
Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study
-
Pavese N., Andrews T.C., Brooks D.J., Ho A.K., Rosser A.E., Barker R.A., Robbins T.W., Sahakian B.J., Dunnett S.B., and Piccini P. Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study. Brain 126 (2003) 1127-1135
-
(2003)
Brain
, vol.126
, pp. 1127-1135
-
-
Pavese, N.1
Andrews, T.C.2
Brooks, D.J.3
Ho, A.K.4
Rosser, A.E.5
Barker, R.A.6
Robbins, T.W.7
Sahakian, B.J.8
Dunnett, S.B.9
Piccini, P.10
-
81
-
-
26144457099
-
Huntington's disease progression measured with serial [11C]-raclopride PET and the UHDRS
-
Pavese N., Andrews T.C., Brooks D.J., Rosser A.E., Barker R.A., Dunnett S.B., Sahakian B.J., and Piccini P. Huntington's disease progression measured with serial [11C]-raclopride PET and the UHDRS. Neurology 56 (2001) A385
-
(2001)
Neurology
, vol.56
-
-
Pavese, N.1
Andrews, T.C.2
Brooks, D.J.3
Rosser, A.E.4
Barker, R.A.5
Dunnett, S.B.6
Sahakian, B.J.7
Piccini, P.8
-
82
-
-
0029011778
-
Rationale for intrastriatal grafting of striatal neuroblasts in patients with Huntington's disease
-
Peschanski M., Césaro P., and Hantraye P. Rationale for intrastriatal grafting of striatal neuroblasts in patients with Huntington's disease. Neuroscience 68 (1995) 273-285
-
(1995)
Neuroscience
, vol.68
, pp. 273-285
-
-
Peschanski, M.1
Césaro, P.2
Hantraye, P.3
-
83
-
-
0030068021
-
What is needed versus what would be interesting to know before undertaking neural transplantation in patients with Huntington's disease
-
Peschanski M., Césaro P., and Hantraye P. What is needed versus what would be interesting to know before undertaking neural transplantation in patients with Huntington's disease. Neuroscience 71 (1996) 899-900
-
(1996)
Neuroscience
, vol.71
, pp. 899-900
-
-
Peschanski, M.1
Césaro, P.2
Hantraye, P.3
-
84
-
-
0041737461
-
Cell therapy for Huntington's disease, the next step forward
-
Peschanski M., and Dunnett S.B. Cell therapy for Huntington's disease, the next step forward. Lancet Neurol. 1 2 (2002) 81
-
(2002)
Lancet Neurol.
, vol.1
, Issue.2
, pp. 81
-
-
Peschanski, M.1
Dunnett, S.B.2
-
85
-
-
0030953742
-
Neuropsychological functioning following fetal striatal transplantation in Huntington's chorea: three case presentations
-
Philpott L.M., Kopyov O.V., Lee A.J., Jacques S., Duma C.M., Caine S., Yang M., and Eagle K.S. Neuropsychological functioning following fetal striatal transplantation in Huntington's chorea: three case presentations. Cell Transplant. 6 (1997) 203-212
-
(1997)
Cell Transplant.
, vol.6
, pp. 203-212
-
-
Philpott, L.M.1
Kopyov, O.V.2
Lee, A.J.3
Jacques, S.4
Duma, C.M.5
Caine, S.6
Yang, M.7
Eagle, K.S.8
-
86
-
-
0033491121
-
Dopamine release from nigral transplants visualised in vivo in a Parkinson's patient
-
Piccini P., Brooks D.J., Björklund A., Gunn R.N., Grasby P.M., Rimoldi O., Brundin P., Hagell P., Rehncrona S., Widner H., and Lindvall O. Dopamine release from nigral transplants visualised in vivo in a Parkinson's patient. Nat. Neurosci. 2 (1999) 1137-1140
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 1137-1140
-
-
Piccini, P.1
Brooks, D.J.2
Björklund, A.3
Gunn, R.N.4
Grasby, P.M.5
Rimoldi, O.6
Brundin, P.7
Hagell, P.8
Rehncrona, S.9
Widner, H.10
Lindvall, O.11
-
87
-
-
0033767269
-
Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts
-
Piccini P., Lindvall O., Björklund A., Brundin P., Hagell P., Ceravolo R., Oertel W., Quinn N., Samuel M., Rehncrona S., Widner H., and Brooks D.J. Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts. Ann. Neurol. 48 (2000) 689-695
-
(2000)
Ann. Neurol.
, vol.48
, pp. 689-695
-
-
Piccini, P.1
Lindvall, O.2
Björklund, A.3
Brundin, P.4
Hagell, P.5
Ceravolo, R.6
Oertel, W.7
Quinn, N.8
Samuel, M.9
Rehncrona, S.10
Widner, H.11
Brooks, D.J.12
-
88
-
-
28544441892
-
Factors affecting the clinical outcome after neural transplantation in Parkinson's disease
-
Piccini P., Pavese N., Hagell P., Reimer J., Björklund A., Oertel W.H., Quinn N.P., Brooks D.J., and Lindvall O. Factors affecting the clinical outcome after neural transplantation in Parkinson's disease. Brain (2005)
-
(2005)
Brain
-
-
Piccini, P.1
Pavese, N.2
Hagell, P.3
Reimer, J.4
Björklund, A.5
Oertel, W.H.6
Quinn, N.P.7
Brooks, D.J.8
Lindvall, O.9
-
89
-
-
0034618649
-
Xenotransplantation-new risks, new gains
-
Platt J.L. Xenotransplantation-new risks, new gains. Nature 407 (2000) 27-30
-
(2000)
Nature
, vol.407
, pp. 27-30
-
-
Platt, J.L.1
-
90
-
-
33847679113
-
-
S. Polgar, J. Ng, Ethics, methodology and the use of placebo controls in surgical trials. Am. J. Bioethics, submitted for publication.
-
-
-
-
91
-
-
0003932887
-
-
HMSO, London
-
Polkinghorne J., Hoffenberg R., Kennedy I., and Macintyre S. Review of the Guidance on the Research Use of Fetuses and Fetal Material (1989), HMSO, London
-
(1989)
Review of the Guidance on the Research Use of Fetuses and Fetal Material
-
-
Polkinghorne, J.1
Hoffenberg, R.2
Kennedy, I.3
Macintyre, S.4
-
92
-
-
0023148062
-
Afferent and efferent connections of striatal grafts implanted into the ibotenic acid lesioned neostriatum in adult rats
-
Pritzel M., Isacson O., Brundin P., Wiklund L., and Björklund A. Afferent and efferent connections of striatal grafts implanted into the ibotenic acid lesioned neostriatum in adult rats. Exp. Brain Res. 65 (1986) 112-126
-
(1986)
Exp. Brain Res.
, vol.65
, pp. 112-126
-
-
Pritzel, M.1
Isacson, O.2
Brundin, P.3
Wiklund, L.4
Björklund, A.5
-
93
-
-
0030029924
-
Transplantation of human striatal tissue into a rodent model of Huntington's disease: phenotypic expression of transplanted neurons and host-to-graft innervation
-
Pundt L.L., Kondoh T., Conrad J.A., and Low W.C. Transplantation of human striatal tissue into a rodent model of Huntington's disease: phenotypic expression of transplanted neurons and host-to-graft innervation. Brain Res. Bull. 39 (1996) 23-32
-
(1996)
Brain Res. Bull.
, vol.39
, pp. 23-32
-
-
Pundt, L.L.1
Kondoh, T.2
Conrad, J.A.3
Low, W.C.4
-
94
-
-
0025120490
-
The clinical application of cell grafting techniques in patients with Parkinson's disease
-
Quinn N.P. The clinical application of cell grafting techniques in patients with Parkinson's disease. Prog. Brain Res. 82 (1990) 619-625
-
(1990)
Prog. Brain Res.
, vol.82
, pp. 619-625
-
-
Quinn, N.P.1
-
95
-
-
0029930390
-
Core assessment programme for intracerebral transplantation in Huntington's disease (CAPIT-HD)
-
Quinn N.P., Brown R., Craufurd D., Goldman S., Hodges J.R., Kieburtz K., Lindvall O., MacMillan J.C., and Roos R.A.C. Core assessment programme for intracerebral transplantation in Huntington's disease (CAPIT-HD). Mov. Disord. 11 (1996) 143-150
-
(1996)
Mov. Disord.
, vol.11
, pp. 143-150
-
-
Quinn, N.P.1
Brown, R.2
Craufurd, D.3
Goldman, S.4
Hodges, J.R.5
Kieburtz, K.6
Lindvall, O.7
MacMillan, J.C.8
Roos, R.A.C.9
-
96
-
-
0028991533
-
18F]fluorodopa uptake in five grafted Parkinsonian patients
-
18F]fluorodopa uptake in five grafted Parkinsonian patients. Ann. Neurol. 38 (1995) 580-588
-
(1995)
Ann. Neurol.
, vol.38
, pp. 580-588
-
-
Rémy, P.1
Samson, Y.2
Hantraye, P.3
Fontaine, A.4
Defer, G.5
Mangin, J.F.6
Fénelon, G.7
Gény, C.8
Ricolfi, F.9
Frouin, V.10
N'Guyen, J.P.11
Jény, R.12
Degos, J.D.13
Peschanski, M.14
Césaro, P.15
-
97
-
-
0032800442
-
In vivo magnetic resonance spectroscopy of human fetal neural transplants
-
Ross B.D., Hoang T.Q., Blüml S., Dubowitz D.J., Kopyov O.V., Jacques D.B., Lin A., Seymour K., and Tan J. In vivo magnetic resonance spectroscopy of human fetal neural transplants. NMR Biomed. 12 (1999) 221-236
-
(1999)
NMR Biomed.
, vol.12
, pp. 221-236
-
-
Ross, B.D.1
Hoang, T.Q.2
Blüml, S.3
Dubowitz, D.J.4
Kopyov, O.V.5
Jacques, D.B.6
Lin, A.7
Seymour, K.8
Tan, J.9
-
98
-
-
3142640821
-
Huntington's disease: new paths to pathogenesis
-
Ross C.A. Huntington's disease: new paths to pathogenesis. Cell 118 (2004) 4-7
-
(2004)
Cell
, vol.118
, pp. 4-7
-
-
Ross, C.A.1
-
99
-
-
0242490447
-
Staging and preparation of human fetal striatal tissue for UK study of neural transplantation in Huntington's disease
-
Rosser A.E., Barker R.A., Armstrong R.A., Elneil S., Jain M., Hurelbrink C.B., Prentice A., Carne C., Thornton S.R., Hutchinson H., and Dunnett S.B. Staging and preparation of human fetal striatal tissue for UK study of neural transplantation in Huntington's disease. Cell Transplant. 12 (2003) 679-686
-
(2003)
Cell Transplant.
, vol.12
, pp. 679-686
-
-
Rosser, A.E.1
Barker, R.A.2
Armstrong, R.A.3
Elneil, S.4
Jain, M.5
Hurelbrink, C.B.6
Prentice, A.7
Carne, C.8
Thornton, S.R.9
Hutchinson, H.10
Dunnett, S.B.11
-
100
-
-
0036904801
-
Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report (ISRCTN no. 36485475)
-
the NEST-UK consortium
-
Rosser A.E., Barker R.A., Guillard J., Harrower T., Watts C., Pickard J., Dunnett S.B., and the NEST-UK consortium. Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report (ISRCTN no. 36485475). J. Neurol. Neurosurg. Psychiatr. 73 (2002) 678-685
-
(2002)
J. Neurol. Neurosurg. Psychiatr.
, vol.73
, pp. 678-685
-
-
Rosser, A.E.1
Barker, R.A.2
Guillard, J.3
Harrower, T.4
Watts, C.5
Pickard, J.6
Dunnett, S.B.7
-
101
-
-
0007966017
-
Transgenic models of Huntington's disease
-
Sathasivam K., Hobbs C., Mangiarini L., Mahal A., Turmaine M., Doherty P., Davies S.W., and Bates G.P. Transgenic models of Huntington's disease. Philos. Trans. R. Soc. Lond. B 354 (1999) 963-969
-
(1999)
Philos. Trans. R. Soc. Lond. B
, vol.354
, pp. 963-969
-
-
Sathasivam, K.1
Hobbs, C.2
Mangiarini, L.3
Mahal, A.4
Turmaine, M.5
Doherty, P.6
Davies, S.W.7
Bates, G.P.8
-
102
-
-
0025846973
-
Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts
-
Sauer H., and Brundin P. Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts. Rest. Neurol. Neurosci. 2 (1991) 123-135
-
(1991)
Rest. Neurol. Neurosci.
, vol.2
, pp. 123-135
-
-
Sauer, H.1
Brundin, P.2
-
103
-
-
0027342934
-
18F]-6-l-fluorodopa PET studies of graft and host dopaminergic function following fetal mesencephalic transplantation
-
18F]-6-l-fluorodopa PET studies of graft and host dopaminergic function following fetal mesencephalic transplantation. Adv. Neurol. 60 (1993) 715-720
-
(1993)
Adv. Neurol.
, vol.60
, pp. 715-720
-
-
Sawle, G.V.1
-
104
-
-
0027411599
-
The role of positron emission tomography in the assessment of human neurotransplantation
-
Sawle G.V., and Myers R. The role of positron emission tomography in the assessment of human neurotransplantation. Trends Neurosci. 16 (1993) 172-176
-
(1993)
Trends Neurosci.
, vol.16
, pp. 172-176
-
-
Sawle, G.V.1
Myers, R.2
-
105
-
-
11144358364
-
Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice
-
Schilling G., Savonenko A.V., Coonfield M.L., Morton J.L., Vorovich E., Gale A., Neslon C., Chan N., Eaton M., Fromholt D., Ross C.A., and Borchelt D.R. Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice. Exp. Neurol. 187 (2004) 137-149
-
(2004)
Exp. Neurol.
, vol.187
, pp. 137-149
-
-
Schilling, G.1
Savonenko, A.V.2
Coonfield, M.L.3
Morton, J.L.4
Vorovich, E.5
Gale, A.6
Neslon, C.7
Chan, N.8
Eaton, M.9
Fromholt, D.10
Ross, C.A.11
Borchelt, D.R.12
-
106
-
-
0019448060
-
Intracerebral grafting of dissociated CNS tissue suspensions: a new approach for neuronal transplantation to deep brain sites
-
Schmidt R.H., Björklund A., and Stenevi U. Intracerebral grafting of dissociated CNS tissue suspensions: a new approach for neuronal transplantation to deep brain sites. Brain Res. 218 (1981) 347-356
-
(1981)
Brain Res.
, vol.218
, pp. 347-356
-
-
Schmidt, R.H.1
Björklund, A.2
Stenevi, U.3
-
107
-
-
0018695450
-
Ibotenic acid-induced neuronal degeneration: a morphological and neurochemical study
-
Schwarcz R., Hökfelt T., Fuxe K., Jonsson G., Goldstein M., and Terenius L. Ibotenic acid-induced neuronal degeneration: a morphological and neurochemical study. Exp. Brain Res. 37 (1979) 199-216
-
(1979)
Exp. Brain Res.
, vol.37
, pp. 199-216
-
-
Schwarcz, R.1
Hökfelt, T.2
Fuxe, K.3
Jonsson, G.4
Goldstein, M.5
Terenius, L.6
-
108
-
-
0020702374
-
Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain
-
Schwarcz R., Whetsell W.O., and Mangano R.M. Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain. Science 219 (1983) 316-318
-
(1983)
Science
, vol.219
, pp. 316-318
-
-
Schwarcz, R.1
Whetsell, W.O.2
Mangano, R.M.3
-
109
-
-
0029865022
-
Neural transplantation for Huntington's disease: experimental rationale and recommendations for clinical trials
-
Shannon K.M., and Kordower J.H. Neural transplantation for Huntington's disease: experimental rationale and recommendations for clinical trials. Cell Transplant. 5 (1996) 339-352
-
(1996)
Cell Transplant.
, vol.5
, pp. 339-352
-
-
Shannon, K.M.1
Kordower, J.H.2
-
110
-
-
0002496113
-
Ontogeny of the neostriatum
-
Divac I., and Öberg R.G.E. (Eds), Pergamon Press, New York
-
Smart I.H.M., and Sturrock R.R. Ontogeny of the neostriatum. In: Divac I., and Öberg R.G.E. (Eds). The Neostriatum (1979), Pergamon Press, New York 127-146
-
(1979)
The Neostriatum
, pp. 127-146
-
-
Smart, I.H.M.1
Sturrock, R.R.2
-
111
-
-
0024991688
-
Remodeling of intrinsic and afferent systems in neocortex with cortical transplants
-
Sofroniew M.V., Dunnett S.B., and Isacson O. Remodeling of intrinsic and afferent systems in neocortex with cortical transplants. Prog. Brain Res. 82 (1990) 313-320
-
(1990)
Prog. Brain Res.
, vol.82
, pp. 313-320
-
-
Sofroniew, M.V.1
Dunnett, S.B.2
Isacson, O.3
-
112
-
-
0026787932
-
Stereotactic technique and pathophysiological mechanisms of neurotransplantation in Huntington's chorea
-
Sramka M., Rattaj M., Molina H., Vojtassak J., Belan V., and Ruzicky E. Stereotactic technique and pathophysiological mechanisms of neurotransplantation in Huntington's chorea. Stereotact. Funct. Neurosurg. 58 (1992) 79-83
-
(1992)
Stereotact. Funct. Neurosurg.
, vol.58
, pp. 79-83
-
-
Sramka, M.1
Rattaj, M.2
Molina, H.3
Vojtassak, J.4
Belan, V.5
Ruzicky, E.6
-
113
-
-
0017158756
-
Transplantation of central and peripheral monoamine neurons to the adult rat brain: techniques and conditions for survival
-
Stenevi U., Björklund A., and Svendgaard N.-A. Transplantation of central and peripheral monoamine neurons to the adult rat brain: techniques and conditions for survival. Brain Res. 114 (1976) 1-20
-
(1976)
Brain Res.
, vol.114
, pp. 1-20
-
-
Stenevi, U.1
Björklund, A.2
Svendgaard, N.-A.3
-
114
-
-
0032411109
-
Endogenous retroviruses: a potential problem for xenotransplantation?
-
Stoye J.P., Le Tissier P., Takeuchi Y., Patience C., and Weiss R.A. Endogenous retroviruses: a potential problem for xenotransplantation?. Ann. N.Y. Acad. Sci. 862 (1998) 67-74
-
(1998)
Ann. N.Y. Acad. Sci.
, vol.862
, pp. 67-74
-
-
Stoye, J.P.1
Le Tissier, P.2
Takeuchi, Y.3
Patience, C.4
Weiss, R.A.5
-
115
-
-
0028881245
-
Assessment of striatal graft viability in the rat in vivo using a small diameter PET scanner
-
Torres E.M., Fricker R.A., Hume S., Myers R., Opacka-Juffry J., Ashworth S., Brooks D.J., and Dunnett S.B. Assessment of striatal graft viability in the rat in vivo using a small diameter PET scanner. NeuroReport 6 (1995) 2017-2021
-
(1995)
NeuroReport
, vol.6
, pp. 2017-2021
-
-
Torres, E.M.1
Fricker, R.A.2
Hume, S.3
Myers, R.4
Opacka-Juffry, J.5
Ashworth, S.6
Brooks, D.J.7
Dunnett, S.B.8
-
116
-
-
0033838272
-
The morphology, integration and functional efficacy of striatal grafts differs between cell suspensions and tissue pieces
-
Watts C., Brasted P.J., and Dunnett S.B. The morphology, integration and functional efficacy of striatal grafts differs between cell suspensions and tissue pieces. Cell Transplant. 9 (2000) 395-407
-
(2000)
Cell Transplant.
, vol.9
, pp. 395-407
-
-
Watts, C.1
Brasted, P.J.2
Dunnett, S.B.3
-
117
-
-
0034064954
-
Embryonic donor age and dissection influence striatal graft development and functional integration in a rodent model of Huntington's disease
-
Watts C., Brasted P.J., Eagle D.M., and Dunnett S.B. Embryonic donor age and dissection influence striatal graft development and functional integration in a rodent model of Huntington's disease. Exp. Neurol. 163 (2000) 85-97
-
(2000)
Exp. Neurol.
, vol.163
, pp. 85-97
-
-
Watts, C.1
Brasted, P.J.2
Eagle, D.M.3
Dunnett, S.B.4
-
118
-
-
0242407048
-
Evaluation of an MRI-based protocol for cell implantation in four patients with Huntington's disease
-
Watts C., Donovan T., Gillard H., Antoun N.M., Burnstein R., Menon D.K., Carpenter T.A., Fryer T., Thomas D.G.T., and Pickard J.D. Evaluation of an MRI-based protocol for cell implantation in four patients with Huntington's disease. Cell Transplant. 12 (2003) 697-704
-
(2003)
Cell Transplant.
, vol.12
, pp. 697-704
-
-
Watts, C.1
Donovan, T.2
Gillard, H.3
Antoun, N.M.4
Burnstein, R.5
Menon, D.K.6
Carpenter, T.A.7
Fryer, T.8
Thomas, D.G.T.9
Pickard, J.D.10
-
119
-
-
0026603230
-
Anatomy and connectivity of intrastriatal striatal transplants
-
Wictorin K. Anatomy and connectivity of intrastriatal striatal transplants. Prog. Neurobiol. 38 (1992) 611-639
-
(1992)
Prog. Neurobiol.
, vol.38
, pp. 611-639
-
-
Wictorin, K.1
-
120
-
-
0024382430
-
Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum. 2: Cortical afferents
-
Wictorin K., and Björklund A. Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum. 2: Cortical afferents. Neuroscience 30 (1989) 297-311
-
(1989)
Neuroscience
, vol.30
, pp. 297-311
-
-
Wictorin, K.1
Björklund, A.2
-
121
-
-
0023698295
-
Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum. 1: Subcortical afferents
-
Wictorin K., Isacson O., Fischer W., Nothias F., Peschanski M., and Björklund A. Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum. 1: Subcortical afferents. Neuroscience 27 (1988) 547-562
-
(1988)
Neuroscience
, vol.27
, pp. 547-562
-
-
Wictorin, K.1
Isacson, O.2
Fischer, W.3
Nothias, F.4
Peschanski, M.5
Björklund, A.6
-
122
-
-
0024337519
-
Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum. 3: Efferent projecting graft neurons and their relation to host afferents within the grafts
-
Wictorin K., Simerly R.B., Isacson O., Swanson L.W., and Björklund A. Connectivity of striatal grafts implanted into the ibotenic acid-lesioned striatum. 3: Efferent projecting graft neurons and their relation to host afferents within the grafts. Neuroscience 30 (1989) 313-330
-
(1989)
Neuroscience
, vol.30
, pp. 313-330
-
-
Wictorin, K.1
Simerly, R.B.2
Isacson, O.3
Swanson, L.W.4
Björklund, A.5
|