Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: A long-term follow-up study

Lancet Neurology

Volumn 5, Issue 4, 2006, Pages 303-309

  Bachoud Lévi, Anne Catherine ^a,b,c   Gaura, Véronique ^d   Brugières, Pierre ^b   Lefaucheur, Jean Pascal ^b   Boissé, Marie Françoise ^b   Maison, Patrick ^a   Baudic, Sophie ^a   Ribeiro, Maria Joao ^d   Bourdet, Catherine ^b   Remy, Philippe ^b,d   Cesaro, Pierre ^a,b   Hantraye, Philippe ^d   Peschanski, Marc ^a  

^a INSERM   (France)

^b HENRI MONDOR HOSPITAL   (France)

^c ECOLE NORMALE SUPÉRIEURE   (France)

^d SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN FUNCTION; CHOREA; CLINICAL ARTICLE; COGNITION; DISEASE COURSE; DISEASE DURATION; DYSTONIA; ELECTROENCEPHALOGRAM; FOLLOW UP; FRONTAL CORTEX; HUMAN; HUNTINGTON CHOREA; MEMBRANE STEADY POTENTIAL; MOTOR DYSFUNCTION; NERVE GRAFT; NEUROPROTECTION; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PATIENT SELECTION; PRIORITY JOURNAL; RATING SCALE; TREATMENT OUTCOME;

EID: 33644967927     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(06)70381-7     Document Type: Article

References (19)

1. Gaura V, A-C Bachoud-Lévi, M-J Ribeiro Striatal neural grafting improves cortical metabolism in Huntington's disease patients Brain 127 2004 65 72
2. Bachoud-Lévi A-C, P Rémy, J-P Nguyen Motor and cognitive improvements in patients with Huntington's Disease after intracerebral transplantation Lancet 356 2000 1975 1979
3. Bachoud-Lévi A-C, P Hantraye, Peschanski M Fetal neural grafts for Huntington's disease: a prospective view Mov Disord 17 2002 439 444
4. Freeman TB, F Cicchetti, RA Hauser Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology Proc Natl Acad Sci USA 97 2000 13877 13882
5. Lindvall O, Björklund A First step toward cell therapy for Huntington's disease Lancet 356 2000 1945 1946
6. Peschanski M, A-C Bachoud-Lévi, Hantraye P Integrating fetal neural transplants into a therapeutic strategy: the example of Huntington's disease Brain 127 2004 1219 1228
7. Rosser AE, RA Barker, T Harrower Unilateral transplantation of human primary fetal tissue in four patients with Huntington's disease: NEST-UK safety report ISRCTN no 36485475 J Neurol Neurosurg Psychiatry 73 2002 678 685
8. Hauser RA, S Furtado, CR Cimino Bilateral human fetal striatal transplantation in Huntington's disease Neurology 58 2002 687 695
9. Bachoud-Lévi AC, C Bourdet, P Brugières Safety assessment of intrastriatal neural allografts in 5 patients with Huntington's disease Exp Neurol 161 2000 194 202
10. Huntington Study Group Unified Huntington's disease rating scale: reliability and consistency Mov Disord 11 1996 136 142
11. Bachoud-Lévi AC, P Maison, P Bartolomeo Retest effects and cognitive decline in longitudinal follow-up of patients with early HD Neurology 56 2001 1052 1058
12. Kang E, DS Lee, H Kang Age-associated changes of cerebral glucose metabolic activity in both male and female deaf children: parametric analysis using objective volume of interest and voxel-based mapping Neuroimage 22 2004 1453 1553
13. Marder K, H Zhao, RH Myers Rate of functional decline in Huntington's disease Neurology 54 2000 452 458
14. Kremer B, CM Clark, EW Almqvist Influence of lamotrigine on progression of early Huntington disease: a randomized clinical trial Neurology 53 1999 1000 1011
15. Huntington Study Group Randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease Neurology 57 2001 397 404
16. Palfi S, F Conde, D Riche Fetal striatal allografts reverse cognitive deficits in a primate model of Huntington disease Nat Med 4 1998 963 966
17. Furtado S, V Sossi, RA Hauser Positron emission tomography after fetal transplantation in Huntington's disease Ann Neurol 58 2005 331 337
18. Bachoud-Lévi A-C, N Déglon, J-P Nguyen Clinical protocol: neuroprotective gene therapy for Huntington disease using a polymer encapsulated BHK cell line engineered to secrete human CNTF Hum Gene Ther 11 2000 1723 1729
19. Bloch J, AC Bachoud-Lévi, N Déglon Neuroprotective gene therapy for Huntington's disease using polymer encapsulated cells engineered to secrete human CNTF: results of a phase I study Hum Gene Ther 15 2004 968 975