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Volumn 8, Issue 2, 2013, Pages

Curcumin Modulates the Inflammatory Response and Inhibits Subsequent Fibrosis in a Mouse Model of Viral-induced Acute Respiratory Distress Syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CURCUMIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TENASCIN; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84874233851     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057285     Document Type: Article
Times cited : (119)

References (87)
  • 1
    • 0034604129 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome
    • Ware LB, Matthay MA, (2000) The acute respiratory distress syndrome. N Engl J Med 342: 1334-1349.
    • (2000) N Engl J Med , vol.342 , pp. 1334-1349
    • Ware, L.B.1    Matthay, M.A.2
  • 2
    • 26244446442 scopus 로고    scopus 로고
    • Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management
    • Matthay M, Zimmerman G, (2005) Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management. Am J Resp Cell Mol Biol 33: 319-327.
    • (2005) Am J Resp Cell Mol Biol , vol.33 , pp. 319-327
    • Matthay, M.1    Zimmerman, G.2
  • 3
    • 79951844263 scopus 로고    scopus 로고
    • Clinical course and prediction of survival in idiopathic pulmonary fibrosis
    • Ley B, Collard HR, King TE Jr, (2011) Clinical course and prediction of survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 183: 431-440.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 431-440
    • Ley, B.1    Collard, H.R.2    King Jr., T.E.3
  • 5
    • 0036089334 scopus 로고    scopus 로고
    • Respiratory reovirus 1/L induction of diffuse alveolar damage: pulmonary fibrosis is not modulated by corticosteroids in acute respiratory distress syndrome in mice
    • London L, Majeski EI, Altman-Hamamdzic S, Enockson C, Paintlia MK, et al. (2002) Respiratory reovirus 1/L induction of diffuse alveolar damage: pulmonary fibrosis is not modulated by corticosteroids in acute respiratory distress syndrome in mice. Clin Immunol 103: 284-295.
    • (2002) Clin Immunol , vol.103 , pp. 284-295
    • London, L.1    Majeski, E.I.2    Altman-Hamamdzic, S.3    Enockson, C.4    Paintlia, M.K.5
  • 6
    • 0036349501 scopus 로고    scopus 로고
    • Respiratory reovirus 1/L induction of diffuse alveolar damage: a model of acute respiratory distress syndrome
    • London L, Majeski EI, Paintlia MK, Harley RA, London SD, (2002) Respiratory reovirus 1/L induction of diffuse alveolar damage: a model of acute respiratory distress syndrome. Exp Mol Pathol 72: 24-36.
    • (2002) Exp Mol Pathol , vol.72 , pp. 24-36
    • London, L.1    Majeski, E.I.2    Paintlia, M.K.3    Harley, R.A.4    London, S.D.5
  • 7
    • 0037309865 scopus 로고    scopus 로고
    • Differential role for T cells in the development of fibrotic lesions associated with reovirus 1/L-induced bronchiolitis obliterans organizing pneumonia versus Acute Respiratory Distress Syndrome
    • Majeski EI, Harley RA, Bellum SC, London SD, London L, (2003) Differential role for T cells in the development of fibrotic lesions associated with reovirus 1/L-induced bronchiolitis obliterans organizing pneumonia versus Acute Respiratory Distress Syndrome. Am J Respir Cell Mol Biol 28: 208-217.
    • (2003) Am J Respir Cell Mol Biol , vol.28 , pp. 208-217
    • Majeski, E.I.1    Harley, R.A.2    Bellum, S.C.3    London, S.D.4    London, L.5
  • 8
    • 0141648422 scopus 로고    scopus 로고
    • Respiratory reovirus 1/L induction of intraluminal fibrosis, a model of bronchiolitis obliterans organizing pneumonia, is dependent on T lymphocytes
    • Majeski EI, Paintlia MK, Lopez AD, Harley RA, London SD, et al. (2003) Respiratory reovirus 1/L induction of intraluminal fibrosis, a model of bronchiolitis obliterans organizing pneumonia, is dependent on T lymphocytes. Am J Pathol 163: 1467-1479.
    • (2003) Am J Pathol , vol.163 , pp. 1467-1479
    • Majeski, E.I.1    Paintlia, M.K.2    Lopez, A.D.3    Harley, R.A.4    London, S.D.5
  • 9
    • 76249121816 scopus 로고    scopus 로고
    • Differential role of the Fas/Fas ligand apoptotic pathway in inflammation and lung fibrosis associated with reovirus 1/L-induced bronchiolitis obliterans organizing pneumonia and acute respiratory distress syndrome
    • Lopez AD, Avasarala S, Grewal S, Murali AK, London L, (2009) Differential role of the Fas/Fas ligand apoptotic pathway in inflammation and lung fibrosis associated with reovirus 1/L-induced bronchiolitis obliterans organizing pneumonia and acute respiratory distress syndrome. J Immunol 183: 8244-8257.
    • (2009) J Immunol , vol.183 , pp. 8244-8257
    • Lopez, A.D.1    Avasarala, S.2    Grewal, S.3    Murali, A.K.4    London, L.5
  • 10
    • 0015785965 scopus 로고
    • Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent
    • Srimal RC, Dhawan BN, (1973) Pharmacology of diferuloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J Pharm Pharmacol 25: 447-452.
    • (1973) J Pharm Pharmacol , vol.25 , pp. 447-452
    • Srimal, R.C.1    Dhawan, B.N.2
  • 11
    • 33644901007 scopus 로고    scopus 로고
    • Multiple biological activities of curcumin: a short review
    • Maheshwari RK, Singh AK, Gaddipati J, Srimal RC, (2006) Multiple biological activities of curcumin: a short review. Life Sci 78: 2081-2087.
    • (2006) Life Sci , vol.78 , pp. 2081-2087
    • Maheshwari, R.K.1    Singh, A.K.2    Gaddipati, J.3    Srimal, R.C.4
  • 12
    • 0017075410 scopus 로고
    • Antioxidant activity of curcumin and related compounds
    • Sharma OP, (1976) Antioxidant activity of curcumin and related compounds. Biochem Pharmacol 25: 1811-1812.
    • (1976) Biochem Pharmacol , vol.25 , pp. 1811-1812
    • Sharma, O.P.1
  • 15
    • 6044276740 scopus 로고    scopus 로고
    • Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance
    • Sharma RA, Euden SA, Platton SL, Cooke DN, Shafayat A, et al. (2004) Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance. Clin Cancer Res 10: 6847-6854.
    • (2004) Clin Cancer Res , vol.10 , pp. 6847-6854
    • Sharma, R.A.1    Euden, S.A.2    Platton, S.L.3    Cooke, D.N.4    Shafayat, A.5
  • 16
    • 55949117806 scopus 로고    scopus 로고
    • Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases
    • Aggarwal BB, Harikumar KB, (2009) Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol 41: 40-59.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 40-59
    • Aggarwal, B.B.1    Harikumar, K.B.2
  • 17
    • 55949084512 scopus 로고    scopus 로고
    • Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature
    • Anand P, Thomas SG, Kunnumakkara AB, Sundaram C, Harikumar KB, et al. (2008) Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature. Biochem Pharmacol 76: 1590-1611.
    • (2008) Biochem Pharmacol , vol.76 , pp. 1590-1611
    • Anand, P.1    Thomas, S.G.2    Kunnumakkara, A.B.3    Sundaram, C.4    Harikumar, K.B.5
  • 19
    • 2142784187 scopus 로고    scopus 로고
    • Biological properties of curcumin-cellular and molecular mechanisms of action
    • Joe B, Vijaykumar M, Lokesh BR, (2004) Biological properties of curcumin-cellular and molecular mechanisms of action. Crit Rev Food Sci Nutr 44: 97-111.
    • (2004) Crit Rev Food Sci Nutr , vol.44 , pp. 97-111
    • Joe, B.1    Vijaykumar, M.2    Lokesh, B.R.3
  • 21
    • 0034974631 scopus 로고    scopus 로고
    • Depletion of protein kinase Cepsilon in normal and scleroderma lung fibroblasts has opposite effects on tenascin expression
    • Tourkina E, Hoffman S, Fenton JW 2nd, Lipsitz S, Silver RW, et al. (2001) Depletion of protein kinase Cepsilon in normal and scleroderma lung fibroblasts has opposite effects on tenascin expression. Arthritis Rheum 44: 1370-1381.
    • (2001) Arthritis Rheum , vol.44 , pp. 1370-1381
    • Tourkina, E.1    Hoffman, S.2    Fenton 2nd, J.W.3    Lipsitz, S.4    Silver, R.W.5
  • 22
    • 0033778209 scopus 로고    scopus 로고
    • Curcumin inhibition of bleomycin-induced pulmonary fibrosis in rats
    • Punithavathi D, Venkatesan N, Babu M, (2000) Curcumin inhibition of bleomycin-induced pulmonary fibrosis in rats. Br J Pharmacol 131: 169-172.
    • (2000) Br J Pharmacol , vol.131 , pp. 169-172
    • Punithavathi, D.1    Venkatesan, N.2    Babu, M.3
  • 23
    • 0041886512 scopus 로고    scopus 로고
    • Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats
    • Punithavathi D, Venkatesan N, Babu M, (2003) Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats. Br J Pharmacol 139: 1342-1350.
    • (2003) Br J Pharmacol , vol.139 , pp. 1342-1350
    • Punithavathi, D.1    Venkatesan, N.2    Babu, M.3
  • 24
    • 0028955691 scopus 로고
    • Modulation of cyclophosphamide-induced early lung injury by curcumin, an anti-inflammatory antioxidant
    • Venkatesan N, Chandrakasan G, (1995) Modulation of cyclophosphamide-induced early lung injury by curcumin, an anti-inflammatory antioxidant. Mol Cell Biochem 142: 79-87.
    • (1995) Mol Cell Biochem , vol.142 , pp. 79-87
    • Venkatesan, N.1    Chandrakasan, G.2
  • 25
  • 26
    • 17644445641 scopus 로고    scopus 로고
    • Pulmonary protective effects of curcumin against paraquat toxicity
    • Venkatesan N, (2000) Pulmonary protective effects of curcumin against paraquat toxicity. Life Sci 66: PL21-28.
    • (2000) Life Sci , vol.66
    • Venkatesan, N.1
  • 27
    • 0035824748 scopus 로고    scopus 로고
    • Regulation of pro-inflammatory cytokine expression by curcumin in hyaline membrane disease (HMD)
    • Literat A, Su F, Norwicki M, Durand M, Ramanathan R, et al. (2001) Regulation of pro-inflammatory cytokine expression by curcumin in hyaline membrane disease (HMD). Life Sci 70: 253-267.
    • (2001) Life Sci , vol.70 , pp. 253-267
    • Literat, A.1    Su, F.2    Norwicki, M.3    Durand, M.4    Ramanathan, R.5
  • 28
    • 13244289773 scopus 로고    scopus 로고
    • Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity
    • Biswas SK, McClure D, Jimenez LA, Megson IL, Rahman I, (2005) Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxid Redox Signal 7: 32-41.
    • (2005) Antioxid Redox Signal , vol.7 , pp. 32-41
    • Biswas, S.K.1    McClure, D.2    Jimenez, L.A.3    Megson, I.L.4    Rahman, I.5
  • 29
    • 56049109789 scopus 로고    scopus 로고
    • [Protective effect of curcumin on oleic-induced acute lung injury in rats]
    • Zhu RF, Zhou M, He JL, Ding FY, Yu SQ, et al. (2008) [Protective effect of curcumin on oleic-induced acute lung injury in rats]. Zhongguo Zhong Yao Za Zhi 33: 2141-2145.
    • (2008) Zhongguo Zhong Yao Za Zhi , vol.33 , pp. 2141-2145
    • Zhu, R.F.1    Zhou, M.2    He, J.L.3    Ding, F.Y.4    Yu, S.Q.5
  • 30
    • 43249113488 scopus 로고    scopus 로고
    • Targeting the lipopolysaccharides: still a matter of debate?
    • Nahra R, Dellinger RP, (2008) Targeting the lipopolysaccharides: still a matter of debate? Curr Opin Anaesthesiol 21: 98-104.
    • (2008) Curr Opin Anaesthesiol , vol.21 , pp. 98-104
    • Nahra, R.1    Dellinger, R.P.2
  • 31
    • 78650881177 scopus 로고    scopus 로고
    • The effects of a synthetic curcuminoid analogue, 2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone on proinflammatory signaling pathways and CLP-induced lethal sepsis in mice
    • Tham CL, Lam KW, Rajajendram R, Cheah YK, Sulaiman MR, et al. (2011) The effects of a synthetic curcuminoid analogue, 2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone on proinflammatory signaling pathways and CLP-induced lethal sepsis in mice. Eur J Pharmacol 652: 136-144.
    • (2011) Eur J Pharmacol , vol.652 , pp. 136-144
    • Tham, C.L.1    Lam, K.W.2    Rajajendram, R.3    Cheah, Y.K.4    Sulaiman, M.R.5
  • 32
    • 33745605533 scopus 로고    scopus 로고
    • The spice of life: curcumin reduces the mortality associated with experimental sepsis
    • Thiemermann C, (2006) The spice of life: curcumin reduces the mortality associated with experimental sepsis. Crit Care Med 34: 2009-2011.
    • (2006) Crit Care Med , vol.34 , pp. 2009-2011
    • Thiemermann, C.1
  • 34
    • 77956264919 scopus 로고    scopus 로고
    • A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes
    • Sun D, Zhuang X, Xiang X, Liu Y, Zhang S, et al. (2010) A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes. Mol Ther 18: 1606-1614.
    • (2010) Mol Ther , vol.18 , pp. 1606-1614
    • Sun, D.1    Zhuang, X.2    Xiang, X.3    Liu, Y.4    Zhang, S.5
  • 35
    • 57649240408 scopus 로고    scopus 로고
    • Preventive effects of curcumin on different aspiration material-induced lung injury in rats
    • Guzel A, Kanter M, Aksu B, Basaran UN, Yalcin O, et al. (2009) Preventive effects of curcumin on different aspiration material-induced lung injury in rats. Pediatr Surg Int 25: 83-92.
    • (2009) Pediatr Surg Int , vol.25 , pp. 83-92
    • Guzel, A.1    Kanter, M.2    Aksu, B.3    Basaran, U.N.4    Yalcin, O.5
  • 36
    • 0030996173 scopus 로고    scopus 로고
    • Respiratory reovirus 1/L induction of intraluminal fibrosis. A model for the study of bronchiolitis obliterans organizing pneumonia
    • Bellum SC, Dove D, Harley RA, Greene WB, Judson MA, et al. (1997) Respiratory reovirus 1/L induction of intraluminal fibrosis. A model for the study of bronchiolitis obliterans organizing pneumonia. Am J Pathol 150: 2243-2254.
    • (1997) Am J Pathol , vol.150 , pp. 2243-2254
    • Bellum, S.C.1    Dove, D.2    Harley, R.A.3    Greene, W.B.4    Judson, M.A.5
  • 37
    • 0034518978 scopus 로고    scopus 로고
    • Inflammation and structural changes in the airways of patients with atopic and nonatopic asthma. BHR Group
    • Amin K, Ludviksdottir D, Janson C, Nettelbladt O, Bjornsson E, et al. (2000) Inflammation and structural changes in the airways of patients with atopic and nonatopic asthma. BHR Group. Am J Respir Crit Care Med 162: 2295-2301.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 2295-2301
    • Amin, K.1    Ludviksdottir, D.2    Janson, C.3    Nettelbladt, O.4    Bjornsson, E.5
  • 38
    • 0030870119 scopus 로고    scopus 로고
    • Tenascin is increased in airway basement membrane of asthmatics and decreased by an inhaled steroid
    • Laitinen A, Altraja A, Kampe M, Linden M, Virtanen I, et al. (1997) Tenascin is increased in airway basement membrane of asthmatics and decreased by an inhaled steroid. Am J Respir Crit Care Med 156: 951-958.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 951-958
    • Laitinen, A.1    Altraja, A.2    Kampe, M.3    Linden, M.4    Virtanen, I.5
  • 40
    • 0343570029 scopus 로고    scopus 로고
    • Tenascin mRNA expression at the foci of recent injury in usual interstitial pneumonia
    • Paakko P, Kaarteenaho-Wiik R, Pollanen R, Soini Y, (2000) Tenascin mRNA expression at the foci of recent injury in usual interstitial pneumonia. Am J Respir Crit Care Med 161: 967-972.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 967-972
    • Paakko, P.1    Kaarteenaho-Wiik, R.2    Pollanen, R.3    Soini, Y.4
  • 41
    • 78651464823 scopus 로고    scopus 로고
    • Acute respiratory distress syndrome and multiple organ failure
    • Del Sorbo L, Slutsky AS, (2011) Acute respiratory distress syndrome and multiple organ failure. Curr Opin Crit Care 17: 1-6.
    • (2011) Curr Opin Crit Care , vol.17 , pp. 1-6
    • Del Sorbo, L.1    Slutsky, A.S.2
  • 42
    • 70350442859 scopus 로고    scopus 로고
    • Bench-to-bedside review: Inhaled nitric oxide therapy in adults
    • Creagh-Brown BC, Griffiths MJ, Evans TW, (2009) Bench-to-bedside review: Inhaled nitric oxide therapy in adults. Crit Care 13: 221.
    • (2009) Crit Care , vol.13 , pp. 221
    • Creagh-Brown, B.C.1    Griffiths, M.J.2    Evans, T.W.3
  • 43
    • 27944481696 scopus 로고    scopus 로고
    • An old spice with new twists: curcumin, p38 mitogen-activated protein kinase, and apoptosis
    • Lee PJ, (2005) An old spice with new twists: curcumin, p38 mitogen-activated protein kinase, and apoptosis. Crit Care Med 33: 2703-2705.
    • (2005) Crit Care Med , vol.33 , pp. 2703-2705
    • Lee, P.J.1
  • 44
    • 0035174615 scopus 로고    scopus 로고
    • Series introduction: the transcription factor NF-kappaB and human disease
    • Baldwin AS Jr, (2001) Series introduction: the transcription factor NF-kappaB and human disease. J Clin Invest 107: 3-6.
    • (2001) J Clin Invest , vol.107 , pp. 3-6
    • Baldwin Jr., A.S.1
  • 45
    • 0034746919 scopus 로고    scopus 로고
    • NF-kappaB: a key role in inflammatory diseases
    • Tak PP, Firestein GS, (2001) NF-kappaB: a key role in inflammatory diseases. J Clin Invest 107: 7-11.
    • (2001) J Clin Invest , vol.107 , pp. 7-11
    • Tak, P.P.1    Firestein, G.S.2
  • 46
    • 77953213426 scopus 로고    scopus 로고
    • An alternative to lung inflammation and fibrosis
    • Morris GF, (2010) An alternative to lung inflammation and fibrosis. Am J Pathol 176: 2595-2598.
    • (2010) Am J Pathol , vol.176 , pp. 2595-2598
    • Morris, G.F.1
  • 48
    • 84866992657 scopus 로고    scopus 로고
    • Cooperation between classical and alternative NF-κB pathways regulates proinflammatory responses in epithelial cells
    • Tully JE, Nolan JD, Guala AS, Hoffman SM, Roberson EC, et al. (2012) Cooperation between classical and alternative NF-κB pathways regulates proinflammatory responses in epithelial cells. Am J of Resp Cell Mol Biol 47: 497-508.
    • (2012) Am J of Resp Cell Mol Biol , vol.47 , pp. 497-508
    • Tully, J.E.1    Nolan, J.D.2    Guala, A.S.3    Hoffman, S.M.4    Roberson, E.C.5
  • 49
    • 0038132126 scopus 로고    scopus 로고
    • Early alterations in neutrophil activation are associated with outcome in acute lung injury
    • Yang KY, Arcaroli JJ, Abraham E, (2003) Early alterations in neutrophil activation are associated with outcome in acute lung injury. Am J Respir Crit Care Med 167: 1567-1574.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1567-1574
    • Yang, K.Y.1    Arcaroli, J.J.2    Abraham, E.3
  • 50
    • 0034132919 scopus 로고    scopus 로고
    • NF-kappaB regulatory mechanisms in alveolar macrophages from patients with acute respiratory distress syndrome
    • Moine P, McIntyre R, Schwartz MD, Kaneko D, Shenkar R, et al. (2000) NF-kappaB regulatory mechanisms in alveolar macrophages from patients with acute respiratory distress syndrome. Shock 13: 85-91.
    • (2000) Shock , vol.13 , pp. 85-91
    • Moine, P.1    McIntyre, R.2    Schwartz, M.D.3    Kaneko, D.4    Shenkar, R.5
  • 51
    • 0034021896 scopus 로고    scopus 로고
    • Predictive value of nuclear factor kappaB activity and plasma cytokine levels in patients with sepsis
    • Arnalich F, Garcia-Palomero E, Lopez J, Jimenez M, Madero R, et al. (2000) Predictive value of nuclear factor kappaB activity and plasma cytokine levels in patients with sepsis. Infect Immun 68: 1942-1945.
    • (2000) Infect Immun , vol.68 , pp. 1942-1945
    • Arnalich, F.1    Garcia-Palomero, E.2    Lopez, J.3    Jimenez, M.4    Madero, R.5
  • 53
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]
    • Singh S, Aggarwal BB, (1995) Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem 270: 24995-25000.
    • (1995) J Biol Chem , vol.270 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 54
    • 20444402292 scopus 로고    scopus 로고
    • Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kappa B as potential targets
    • Kim GY, Kim KH, Lee SH, Yoon MS, Lee HJ, et al. (2005) Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kappa B as potential targets. J Immunol 174: 8116-8124.
    • (2005) J Immunol , vol.174 , pp. 8116-8124
    • Kim, G.Y.1    Kim, K.H.2    Lee, S.H.3    Yoon, M.S.4    Lee, H.J.5
  • 55
    • 84868571564 scopus 로고    scopus 로고
    • Curcumin Attenuates Cardiopulmonary Bypass-Induced Lung Oxidative Damage in Rats
    • Liu K, Chen HL, Huang H, Jing H, Dong GH, et al. (2012) Curcumin Attenuates Cardiopulmonary Bypass-Induced Lung Oxidative Damage in Rats. J Cardiovasc Pharmacol Ther 17: 395-402.
    • (2012) J Cardiovasc Pharmacol Ther , vol.17 , pp. 395-402
    • Liu, K.1    Chen, H.L.2    Huang, H.3    Jing, H.4    Dong, G.H.5
  • 56
    • 84859099805 scopus 로고    scopus 로고
    • The preventative role of curcumin on the lung inflammatory response induced by cardiopulmonary bypass in rats
    • Liu K, Shen L, Wang J, Dong G, Wu H, et al. (2012) The preventative role of curcumin on the lung inflammatory response induced by cardiopulmonary bypass in rats. J Surg Res 174: 73-82.
    • (2012) J Surg Res , vol.174 , pp. 73-82
    • Liu, K.1    Shen, L.2    Wang, J.3    Dong, G.4    Wu, H.5
  • 57
    • 79960330994 scopus 로고    scopus 로고
    • Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kappaB inhibition
    • Oh SW, Cha JY, Jung JE, Chang BC, Kwon HJ, et al. (2011) Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-kappaB inhibition. J Ethnopharmacol 136: 414-421.
    • (2011) J Ethnopharmacol , vol.136 , pp. 414-421
    • Oh, S.W.1    Cha, J.Y.2    Jung, J.E.3    Chang, B.C.4    Kwon, H.J.5
  • 58
    • 35348940144 scopus 로고    scopus 로고
    • Pathobiology of transforming growth factor beta in cancer, fibrosis and immunologic disease, and therapeutic considerations
    • Prud'homme GJ, (2007) Pathobiology of transforming growth factor beta in cancer, fibrosis and immunologic disease, and therapeutic considerations. Lab Invest 87: 1077-1091.
    • (2007) Lab Invest , vol.87 , pp. 1077-1091
    • Prud'homme, G.J.1
  • 60
    • 35448988114 scopus 로고    scopus 로고
    • Molecular targets in pulmonary fibrosis: the myofibroblast in focus
    • Scotton CJ, Chambers RC, (2007) Molecular targets in pulmonary fibrosis: the myofibroblast in focus. Chest 132: 1311-1321.
    • (2007) Chest , vol.132 , pp. 1311-1321
    • Scotton, C.J.1    Chambers, R.C.2
  • 61
    • 0037391385 scopus 로고    scopus 로고
    • Transforming growth factor-beta: a mediator of cell regulation in acute respiratory distress syndrome
    • Dhainaut JF, Charpentier J, Chiche JD, (2003) Transforming growth factor-beta: a mediator of cell regulation in acute respiratory distress syndrome. Crit Care Med 31: S258-264.
    • (2003) Crit Care Med , vol.31
    • Dhainaut, J.F.1    Charpentier, J.2    Chiche, J.D.3
  • 62
    • 12944304176 scopus 로고    scopus 로고
    • Active transforming growth factor-beta1 activates the procollagen I promoter in patients with acute lung injury
    • Budinger GR, Chandel NS, Donnelly HK, Eisenbart J, Oberoi M, et al. (2005) Active transforming growth factor-beta1 activates the procollagen I promoter in patients with acute lung injury. Intensive Care Med 31: 121-128.
    • (2005) Intensive Care Med , vol.31 , pp. 121-128
    • Budinger, G.R.1    Chandel, N.S.2    Donnelly, H.K.3    Eisenbart, J.4    Oberoi, M.5
  • 64
    • 0029768740 scopus 로고    scopus 로고
    • Protective effect of curcumin, ellagic acid and bixin on radiation induced toxicity
    • Thresiamma KC, George J, Kuttan R, (1996) Protective effect of curcumin, ellagic acid and bixin on radiation induced toxicity. Indian J Exp Biol 34: 845-847.
    • (1996) Indian J Exp Biol , vol.34 , pp. 845-847
    • Thresiamma, K.C.1    George, J.2    Kuttan, R.3
  • 65
    • 34247642629 scopus 로고    scopus 로고
    • Therapies for bleomycin induced lung fibrosis through regulation of TGF-beta1 induced collagen gene expression
    • Cutroneo KR, White SL, Phan SH, Ehrlich HP, (2007) Therapies for bleomycin induced lung fibrosis through regulation of TGF-beta1 induced collagen gene expression. J Cell Physiol 211: 585-589.
    • (2007) J Cell Physiol , vol.211 , pp. 585-589
    • Cutroneo, K.R.1    White, S.L.2    Phan, S.H.3    Ehrlich, H.P.4
  • 66
    • 34248577489 scopus 로고    scopus 로고
    • Effects of curcumin in treatment of experimental pulmonary fibrosis: a comparison with hydrocortisone
    • Xu M, Deng B, Chow YL, Zhao ZZ, Hu B, (2007) Effects of curcumin in treatment of experimental pulmonary fibrosis: a comparison with hydrocortisone. J Ethnopharmacol 112: 292-299.
    • (2007) J Ethnopharmacol , vol.112 , pp. 292-299
    • Xu, M.1    Deng, B.2    Chow, Y.L.3    Zhao, Z.Z.4    Hu, B.5
  • 67
    • 84862833397 scopus 로고    scopus 로고
    • [Effect of curcumin on the expression of collagen type I protein and transforming growth factor-beta1 mRNA in pulmonary fibrosis rats]
    • Chen B, Zhang DP, Gao W, (2008) [Effect of curcumin on the expression of collagen type I protein and transforming growth factor-beta1 mRNA in pulmonary fibrosis rats]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 26: 257-261.
    • (2008) Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi , vol.26 , pp. 257-261
    • Chen, B.1    Zhang, D.P.2    Gao, W.3
  • 68
    • 51649095046 scopus 로고    scopus 로고
    • [The effect of curcumin on bleomycin-induced pulmonary fibrosis in rats]
    • Zhang DP, Qiu H, Zhuang Y, Meng FQ, (2007) [The effect of curcumin on bleomycin-induced pulmonary fibrosis in rats]. Zhonghua Jie He He Hu Xi Za Zhi 30: 197-201.
    • (2007) Zhonghua Jie He He Hu Xi Za Zhi , vol.30 , pp. 197-201
    • Zhang, D.P.1    Qiu, H.2    Zhuang, Y.3    Meng, F.Q.4
  • 70
    • 77949317039 scopus 로고    scopus 로고
    • [Effects of curcumin on TNF-alpha and TGF-beta1 in serum and lung tissue of SiO2-induced fibrosis in mice]
    • Jiang ZY, Zou L, Shi SS, Lu YR, Dong J, et al. (2009) [Effects of curcumin on TNF-alpha and TGF-beta1 in serum and lung tissue of SiO2-induced fibrosis in mice]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 25: 399-401.
    • (2009) Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi , vol.25 , pp. 399-401
    • Jiang, Z.Y.1    Zou, L.2    Shi, S.S.3    Lu, Y.R.4    Dong, J.5
  • 71
    • 80051572060 scopus 로고    scopus 로고
    • Curcumin suppresses TGF-beta signaling by inhibition of TGIF degradation in scleroderma fibroblasts
    • Song K, Peng S, Sun Z, Li H, Yang R, (2011) Curcumin suppresses TGF-beta signaling by inhibition of TGIF degradation in scleroderma fibroblasts. Biochem Biophys Res Commun 411: 821-825.
    • (2011) Biochem Biophys Res Commun , vol.411 , pp. 821-825
    • Song, K.1    Peng, S.2    Sun, Z.3    Li, H.4    Yang, R.5
  • 72
    • 0035178406 scopus 로고    scopus 로고
    • Role of protein kinase C-delta in the regulation of collagen gene expression in scleroderma fibroblasts
    • Jimenez SA, Gaidarova S, Saitta B, Sandorfi N, Herrich DJ, et al. (2001) Role of protein kinase C-delta in the regulation of collagen gene expression in scleroderma fibroblasts. J Clin Invest 108: 1395-1403.
    • (2001) J Clin Invest , vol.108 , pp. 1395-1403
    • Jimenez, S.A.1    Gaidarova, S.2    Saitta, B.3    Sandorfi, N.4    Herrich, D.J.5
  • 73
    • 78649326492 scopus 로고    scopus 로고
    • Suppression of TGF-beta1/SMAD pathway and extracellular matrix production in primary keloid fibroblasts by curcuminoids: its potential therapeutic use in the chemoprevention of keloid
    • Hsu YC, Chen MJ, Yu YM, Ko SY, Chang CC, (2010) Suppression of TGF-beta1/SMAD pathway and extracellular matrix production in primary keloid fibroblasts by curcuminoids: its potential therapeutic use in the chemoprevention of keloid. Arch Dermatol Res 302: 717-724.
    • (2010) Arch Dermatol Res , vol.302 , pp. 717-724
    • Hsu, Y.C.1    Chen, M.J.2    Yu, Y.M.3    Ko, S.Y.4    Chang, C.C.5
  • 74
    • 3042766204 scopus 로고    scopus 로고
    • Curcumin blocks multiple sites of the TGF-beta signaling cascade in renal cells
    • Gaedeke J, Noble NA, Border WA, (2004) Curcumin blocks multiple sites of the TGF-beta signaling cascade in renal cells. Kidney Int 66: 112-120.
    • (2004) Kidney Int , vol.66 , pp. 112-120
    • Gaedeke, J.1    Noble, N.A.2    Border, W.A.3
  • 75
    • 34047235730 scopus 로고    scopus 로고
    • Deletion of protein kinase C-epsilon signaling pathway induces glomerulosclerosis and tubulointerstitial fibrosis in vivo
    • Meier M, Menne J, Park JK, Holtz M, Gueler F, et al. (2007) Deletion of protein kinase C-epsilon signaling pathway induces glomerulosclerosis and tubulointerstitial fibrosis in vivo. J Am Soc Nephrol 18: 1190-1198.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1190-1198
    • Meier, M.1    Menne, J.2    Park, J.K.3    Holtz, M.4    Gueler, F.5
  • 76
    • 9444252295 scopus 로고    scopus 로고
    • Activation of PPARgamma is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in vitro
    • Zheng S, Chen A, (2004) Activation of PPARgamma is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in vitro. Biochem J 384: 149-157.
    • (2004) Biochem J , vol.384 , pp. 149-157
    • Zheng, S.1    Chen, A.2
  • 77
    • 33645803853 scopus 로고    scopus 로고
    • Curcumin suppresses the expression of extracellular matrix genes in activated hepatic stellate cells by inhibiting gene expression of connective tissue growth factor
    • Zheng S, Chen A, (2006) Curcumin suppresses the expression of extracellular matrix genes in activated hepatic stellate cells by inhibiting gene expression of connective tissue growth factor. Am J Physiol Gastrointest Liver Physiol 290: G883-893.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Zheng, S.1    Chen, A.2
  • 78
    • 33846146367 scopus 로고    scopus 로고
    • Disruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells
    • Zheng S, Chen A, (2007) Disruption of transforming growth factor-beta signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor-gamma in rat hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol 292: G113-123.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Zheng, S.1    Chen, A.2
  • 79
    • 0033567086 scopus 로고    scopus 로고
    • Soluble Fas ligand induces epithelial cell apoptosis in humans with acute lung injury (ARDS)
    • Matute-Bello G, Liles WC, Steinberg KP, Kiener PA, Mongovin S, et al. (1999) Soluble Fas ligand induces epithelial cell apoptosis in humans with acute lung injury (ARDS). J Immunol 163: 2217-2225.
    • (1999) J Immunol , vol.163 , pp. 2217-2225
    • Matute-Bello, G.1    Liles, W.C.2    Steinberg, K.P.3    Kiener, P.A.4    Mongovin, S.5
  • 81
    • 0036841093 scopus 로고    scopus 로고
    • Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome
    • Albertine KH, Soulier MF, Wang Z, Ishizaka A, Hashimoto S, et al. (2002) Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am J Pathol 161: 1783-1796.
    • (2002) Am J Pathol , vol.161 , pp. 1783-1796
    • Albertine, K.H.1    Soulier, M.F.2    Wang, Z.3    Ishizaka, A.4    Hashimoto, S.5
  • 82
    • 0033559424 scopus 로고    scopus 로고
    • Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils
    • Nick JA, Avdi NJ, Young SK, Lehman LA, McDonald PP, et al. (1999) Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils. J Clin Invest 103: 851-858.
    • (1999) J Clin Invest , vol.103 , pp. 851-858
    • Nick, J.A.1    Avdi, N.J.2    Young, S.K.3    Lehman, L.A.4    McDonald, P.P.5
  • 83
    • 27944451010 scopus 로고    scopus 로고
    • Proapoptotic effect of curcumin on human neutrophils: activation of the p38 mitogen-activated protein kinase pathway
    • Hu M, Du Q, Vancurova I, Lin X, Miller EJ, et al. (2005) Proapoptotic effect of curcumin on human neutrophils: activation of the p38 mitogen-activated protein kinase pathway. Crit Care Med 33: 2571-2578.
    • (2005) Crit Care Med , vol.33 , pp. 2571-2578
    • Hu, M.1    Du, Q.2    Vancurova, I.3    Lin, X.4    Miller, E.J.5
  • 84
    • 84870447823 scopus 로고    scopus 로고
    • Curcumin suppresses growth of mesothelioma cells in vitro and in vivo, in part, by stimulating apoptosis
    • Wang Y, Rishi AK, Wu W, Polin L, Sharma S, et al. (2011) Curcumin suppresses growth of mesothelioma cells in vitro and in vivo, in part, by stimulating apoptosis. Mol Cell Biochem 357: 83-94.
    • (2011) Mol Cell Biochem , vol.357 , pp. 83-94
    • Wang, Y.1    Rishi, A.K.2    Wu, W.3    Polin, L.4    Sharma, S.5
  • 85
    • 80051746642 scopus 로고    scopus 로고
    • Curcumin induces EGFR degradation in lung adenocarcinoma and modulates p38 activation in intestine: the versatile adjuvant for gefitinib therapy
    • Lee JY, Lee YM, Chang GC, Yu SL, Hsieh WY, et al. (2011) Curcumin induces EGFR degradation in lung adenocarcinoma and modulates p38 activation in intestine: the versatile adjuvant for gefitinib therapy. PLoS One 6: e23756.
    • (2011) PLoS One , vol.6
    • Lee, J.Y.1    Lee, Y.M.2    Chang, G.C.3    Yu, S.L.4    Hsieh, W.Y.5
  • 86
    • 84865831359 scopus 로고    scopus 로고
    • Pulmonary administration of a water-soluble curcumin complex reduces severity of acute lung injury
    • Suresh MV, Wagner MC, Rosania GR, Stringer KA, Min KA, et al. (2012) Pulmonary administration of a water-soluble curcumin complex reduces severity of acute lung injury. Am J Respir Cell Mol Biol 47: 280-287.
    • (2012) Am J Respir Cell Mol Biol , vol.47 , pp. 280-287
    • Suresh, M.V.1    Wagner, M.C.2    Rosania, G.R.3    Stringer, K.A.4    Min, K.A.5
  • 87
    • 77950501529 scopus 로고    scopus 로고
    • Curcumin alone and in combination with augmentin protects against pulmonary inflammation and acute lung injury generated during Klebsiella pneumoniae B5055-induced lung infection in BALB/c mice
    • Bansal S, Chhibber S, (2010) Curcumin alone and in combination with augmentin protects against pulmonary inflammation and acute lung injury generated during Klebsiella pneumoniae B5055-induced lung infection in BALB/c mice. J Med Microbiol 59: 429-437.
    • (2010) J Med Microbiol , vol.59 , pp. 429-437
    • Bansal, S.1    Chhibber, S.2


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