Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats

British Journal of Pharmacology

Volumn 139, Issue 7, 2003, Pages 1342-1350

  Punithavathi, Durairaj ^a   Venkatesan, Narayanan ^a,b   Babu, Mary ^a  

^a CENTRAL LEATHER RESEARCH INSTITUTE   (India)

^b UNIVERSITÉ DE LORRAINE   (France)

Author keywords

Amiodarone; Collagen; Curcumin; Superoxide anion; Tumor necrosis factor

Indexed keywords

AMIODARONE; COLLAGEN; COLLAGEN TYPE 1; CURCUMIN; HYDROXYPROLINE; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN; PROTEIN C JUN; SUPEROXIDE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; EOSINOPHIL; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROSIS; LUNG LAVAGE; MALE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT;

AMIODARONE; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; COLLAGEN TYPE I; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; INSTILLATION, DRUG; INTUBATION, GASTROINTESTINAL; L-LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGES, ALVEOLAR; MALE; PEROXIDASE; PROTO-ONCOGENE PROTEINS C-JUN; PULMONARY FIBROSIS; RATS; RATS, INBRED F344; SUPEROXIDES; TIME FACTORS; TRACHEA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0041886512     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705362     Document Type: Article

References (37)

1. ABE, Y., HASHIMOTO, S. & HORIE, T. (1999). Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages. Pharmacol. Res., 39, 41-47.
2. AHSAN, H., PARVEEN, N., KHAN, N.U. & HADI, S.M. (1999). Prooxidant, anti-oxidant and cleavage activities on DNA of curcumin and its derivatives demethoxycurcumin and bisdemethoxycurcumin. Chem. Biol. Interact., 121, 161-175.
3. AMMON, H.P.T. & WAHL, M.A. (1991). Pharmacology of Curcuma longa. Planta. Med., 57, 1-7.
4. ANGEL, P. & KARIN, M. (1991). The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta, 1072, 129-157.
5. ARAUJO, C.A.C. & LEON, L.L. (2001). Biological activities of Curcuma longa L. Mem. Inst. Oswaldo Cruz., 96, 723-728.
6. BABIOR, B.M., KIPNES, R.S. & CURNUTTE, J.T. (1973). Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J. Clin. Invest., 2, 741-744.
7. BORDER, W.A. & NOBLE, N.A. (1994). Transforming growth factor beta in tissue fibrosis. N. Engl. J. Med., 331, 1286-1292.
8. BRADLEY, P.P., PRIEBAT, D.A., CHRISTENSEN, R.D. & ROTHSTEIN, G. (1982). Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J. Invest. Dermatol., 78, 206-209.
9. CHENG, A.L., LIN, J.K., HSU, M.M., SHEN, T.S., KO, J.Y., LIN, J.T., WU, M.S., YU, H.S., JEE, S.H., CHEN, G.S., CHEN, T.M., CHEN, C.A., LAI, M.K., PU, Y.S., PAN, M.H., WANG, U.J., TSAI, C.C. & HSIEH, C.Y. (1998). Phase I chemopreventiaon clinical trial of curcumin. Proc. Am. Soc. Clin. Oncol., 17, 558.
10. CHUNG, K.Y., AGARWAL, A., UITTO, J. & MAUVIEL, A. (1996). An AP-1 binding sequence is essential for regulation of the human alpha2(I) collagen (COL1A2) promoter activity by transforming growth factor-beta. J. Biol. Chem., 271, 3272-3278.
11. CHUNG, W.H., BENNETT, B.M., RACZ, W.J., BRIEN, J.F. & MASSEY, T.E. (2001). Induction of c-jun and TGF-beta 1 in Fischer 344 rats during amiodarone-induced pulmonary fibrosis. Am. J. Physiol., 281, L1180-L1188.
12. DEODHAR, S.D., SETHI, R. & SRIMAL, R.C. (1980). Preliminary study on antirheumatic activity of curcumin (diferuloyl methane). Indian J. Med. Res., 71, 632-634.
13. GESCHER, A., PASTORINO, U., PLUMMER, S.M. & MANSON, M.M. (1998). Suppression of tumor development by substances derived from the diet - mechanisms and clinical implications. Br. J. Clin. Pharmacol., 45, 1-12.
14. GILL, J., HEEL, R.C. & FITTON, A. (1992). Amiodarone: an overview of its pharmacological properties, and review of its therapeutic use in cardiac arrhythmias. Drugs, 43, 69-110.
15. GIRI, S.N. & WANG, Q. (1989). Mechanisms of bleomycin-induced lung injury. Comments Toxicol., 3, 145-176.
16. KANG, H.C., NAN, J.X., PARK, P.H., KIM, J.M., LEE, S.H., WOO, S.W., ZHAO, Y.Z., PARK, E.J. & SOHN, D.H. (2002). Curcumin inhibits collagen synthesis and hepatic stellate cell activation in-vivo and in-vitro. J. Pharm. Pharmacol., 54, 119-126.
17. KENNEDY, T.P., GORDON, G.B., PAKY, A., McSHANE, A., ADKINSON, N.F.J., PETERS, S.P., FRIDAY, K., JACKMAN, W., SCIUTO, A.M. & GURTNER, G.H. (1988). Amiodarone causes acute oxidant lung injury in ventillated and perfused rabbit lungs. J. Cardiovasc. Pharmacol., 12, 23-36.
18. KIM, S.J., ANGEL, P., LAFYATIS, R., HATTORI, K., KIM, K.Y., SPORN, M.B., KARIN, M. & ROBERTS, A.B. (1990). Autoinduction of transforming growth factor-β1 is mediated by the AP-1 complex. Mol. Cell. Biol., 10, 1492-1497.
19. KUCHANDY, E. & RAO, M.N.A. (1990). Oxygen radical scavenging activity of curcumin. Int. J. Pharm., 58, 237-240.
20. KUMAR, A., DHAWAN, S., HARDEGEN, N.J. & AGGARWAL, B.B. (1998). Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-kappaB activation. Biochem. Pharmacol., 55, 775-783.
21. LEEDER, R.G., BRIEN, J.F. & MASSEY, T.E. (1994). Investigation of the role of oxidative stress in amiodarone-induced pulmonary toxicity in the hamster. Can. J. Physiol. Pharmacol., 72, 613-621.
22. MUKHOPADHYAY, A., BASU, N., GHATAK, N. & GUJRAL, P.K. (1982). Anti-inflammatory and irritant activities of curcumin analogues in rats. Agents Actions, 12, 508-515.
23. NIRMALA, C. & PUVANAKRISHNAN, P. (1996). Protective role of curcumin against isoproterenol induced myocardial infarction in rats. Mol. Cell. Bioehem., 159, 85-93.
24. PADMAVATHY, B., NIRANJALI, S. & DEVARAJ, H. (1992). Lung injury by amiodarone, an antiarrhythmic drug, in male rats. Indian J. Exp. Biol., 30, 653-654.
25. POSTLETHWAITE, A.E. & SEYER, J.M. (1990). Stimulation of fibroblast chemotaxis by human recombinant tumor necrosis factor alpha (TNF-alpha) and a synthetic TNF-alpha 31-68 peptide. J. Exp. Med., 172, 1749-1756.
26. PUNITHAVATHI, D., VENKATESAN, N. & BABU, M. (2000). Curcumin inhibition of bleomycin-induced pulmonary fibrosis in rats. Br. J. Pharmacol., 131, 169-172.
27. RAO, T.S., BASU, N. & SIDDIQUI, H.H. (1982). Anti-inflammatory activity of curcumin analogues. Indian J. Med. Res., 75, 574-578.
28. REASOR, M.J. & KACEW, S. (1996). An evaluation of possible mechanisms underlying amiodarone-induced pulmonary toxicity. Proc. Soc. Exp. Biol. Med., 212, 297-304.
29. REINHART, P.G. & GAIROLA, C.G. (1997). Amiodarone-induced pulmonary toxicity in Fischer rats: release of tumor necrosis factor alpha and transforming growth factor beta by pulmonary alveolar macrophages. J. Toxicol. Environ. Health, 52, 353-365.
30. SATO, M., CORDIS, G.A., MAULIK, N. & DAS, D.K. (2000). SAPKs regulation of ischemic preconditioning. Am. J. Physiol., 279, H901-H907.
31. SATOSKAR, R.R., SHAH, S.J. & SHENOY, S.G. (1986). Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with post-operative inflammation. Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 651-656.
32. TAYLOR, M.D., VAN DYKE, K., BOWMAN, L.L., MILES, P.R., HUBBS, A.F., MASON, R.J., SHANNON, K. & REASOR, M.J (2000). A characterization of amiodarone-induced pulmonary toxicity in F344 rats and identification of surfactant protein-D as a potential biomarker for the development of the toxicity. Toxicol. Appl. Pharmacol., 167, 182-190.
33. VENKATESAN, N., PUNITHAVATHI, D. & CHANDRAKASAN, G. (1998). Glycoprotein composition in cyclophosphamide-induced lung fibrosis. Biochim. Biophys. Acta, 1407, 125-134.
34. WANG, Q., HOLLINGER, M.A. & GIRI, S.N. (1992). Attenuation of amiodarone-induced lung fibrosis and phospholipidosis in hamsters by taurine and/or niacin treatment. J. Pharmacol. Exp. Ther., 262, 127-132.
35. WILSON, B.D., JAWORSKI, A.J., DONNER, M.E. & LIPPMANN, M.L. (1989). Amiodarone-induced pulmonary toxicity in the rat. Lung, 167, 301-311.
36. WILSON, B.D. & LIPMANN, M.L. (1993). Amiodarone pulmonary toxicity in the rat is associated with increased lavage immunoglobulin and alveolar macrophages primed for increased interleukin-1 secretion. Am. J. Respir. Cell Mol. Biol., 9, 295-299.
37. WOESSNER JR., J.F. (1961). The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch. Biochem. Biophys., 93, 440-447.