-
1
-
-
0032489358
-
Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance
-
Kahn BB, (1998) Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance. Cell 92: 593-596.
-
(1998)
Cell
, vol.92
, pp. 593-596
-
-
Kahn, B.B.1
-
2
-
-
70450193472
-
Human genetics illuminates the paths to metabolic disease
-
O'Rahilly S, (2009) Human genetics illuminates the paths to metabolic disease. Nature 462: 307-314.
-
(2009)
Nature
, vol.462
, pp. 307-314
-
-
O'Rahilly, S.1
-
3
-
-
35948940879
-
Polymorphisms in the gene encoding the voltage-dependent Ca2+ channel CaV2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
-
Holmkvist J, Tojjar D, Almgren P, Lyssenko V, Lindgren CM, et al. (2007) Polymorphisms in the gene encoding the voltage-dependent Ca2+ channel CaV2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion. Diabetologia 50: 2467-2475.
-
(2007)
Diabetologia
, vol.50
, pp. 2467-2475
-
-
Holmkvist, J.1
Tojjar, D.2
Almgren, P.3
Lyssenko, V.4
Lindgren, C.M.5
-
4
-
-
0037317981
-
Large scale association studies of variants in genes nencoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
-
Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, et al. (2003) Large scale association studies of variants in genes nencoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes 52: 568-572.
-
(2003)
Diabetes
, vol.52
, pp. 568-572
-
-
Gloyn, A.L.1
Weedon, M.N.2
Owen, K.R.3
Turner, M.J.4
Knight, B.A.5
-
5
-
-
3543022707
-
Molecular defects in insulin secretion in type-2 diabetes
-
Ashcroft FM, Rorsman P, (2004) Molecular defects in insulin secretion in type-2 diabetes. Rev Endocr Metab Disord 5: 135-142.
-
(2004)
Rev Endocr Metab Disord
, vol.5
, pp. 135-142
-
-
Ashcroft, F.M.1
Rorsman, P.2
-
6
-
-
50449085998
-
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
-
Yasuda K, Miyake K, Horikawa Y, Hara K, Osawa H, et al. (2008) Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet 40: 1092-1097.
-
(2008)
Nat Genet
, vol.40
, pp. 1092-1097
-
-
Yasuda, K.1
Miyake, K.2
Horikawa, Y.3
Hara, K.4
Osawa, H.5
-
7
-
-
69449108010
-
Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
-
Qi QB, Li HX, Loos RJF, Liu C, Wu Y, et al. (2009) Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. Hum Mol Genet 18: 3508-3515.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3508-3515
-
-
Qi, Q.B.1
Li, H.X.2
Loos, R.J.F.3
Liu, C.4
Wu, Y.5
-
8
-
-
67349205597
-
Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population
-
Hu C, Wang C, Zhang R, Ma X, Wang J, et al. (2009) Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population. Diabetologia 52: 1322-1325.
-
(2009)
Diabetologia
, vol.52
, pp. 1322-1325
-
-
Hu, C.1
Wang, C.2
Zhang, R.3
Ma, X.4
Wang, J.5
-
9
-
-
50449085212
-
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
-
Unoki H, Takahashi A, Kawaguchi T, Hara K, Horikoshi M, et al. (2008) SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat Genet 40: 1098-1102.
-
(2008)
Nat Genet
, vol.40
, pp. 1098-1102
-
-
Unoki, H.1
Takahashi, A.2
Kawaguchi, T.3
Hara, K.4
Horikoshi, M.5
-
10
-
-
84863207933
-
Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes
-
Rosengren AH, Braun M, Mahdi T, Andersson SA, Travers ME, et al. (2012) Reduced Insulin Exocytosis in Human Pancreatic β-Cells With Gene Variants Linked to Type 2 Diabetes. Diabetes 61: 1726-33.
-
(2012)
Diabetes
, vol.61
, pp. 1726-1733
-
-
Rosengren, A.H.1
Braun, M.2
Mahdi, T.3
Andersson, S.A.4
Travers, M.E.5
-
11
-
-
84857709224
-
Common variants in the type 2 diabetes KCNQ1 Gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp
-
van Vliet-Ostaptchouk JV, van Haeften TW, Landman GW, Reiling E, Kleefstra N, et al. (2012) Common variants in the type 2 diabetes KCNQ1 Gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp. PLoS ONE 7: e32148.
-
(2012)
PLoS ONE
, vol.7
-
-
van Vliet-Ostaptchouk, J.V.1
van Haeften, T.W.2
Landman, G.W.3
Reiling, E.4
Kleefstra, N.5
-
12
-
-
34548673557
-
Regulation of excitability by potassium channels
-
Pongs O, (2008) Regulation of excitability by potassium channels. Results Probl Cell Differ 44: 145-161.
-
(2008)
Results Probl Cell Differ
, vol.44
, pp. 145-161
-
-
Pongs, O.1
-
13
-
-
0042879894
-
Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets
-
MacDonald PE, Wheeler MB, (2003) Voltage-dependent K(+) channels in pancreatic beta cells: role, regulation and potential as therapeutic targets. Diabetologia 46: 1046-1062.
-
(2003)
Diabetologia
, vol.46
, pp. 1046-1062
-
-
MacDonald, P.E.1
Wheeler, M.B.2
-
14
-
-
34548266670
-
Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion
-
Jacobson DA, Kuznetsov A, Lopez JP, Kash S, Ammälä CE, et al. (2007) Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion. Cell Metab 6: 229-235.
-
(2007)
Cell Metab
, vol.6
, pp. 229-235
-
-
Jacobson, D.A.1
Kuznetsov, A.2
Lopez, J.P.3
Kash, S.4
Ammälä, C.E.5
-
15
-
-
9044240040
-
Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias
-
Wang Q, Curran ME, Splawski I, Burn TC, Millholland JM, et al. (1996) Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias. Nat Genet 12: 17-23.
-
(1996)
Nat Genet
, vol.12
, pp. 17-23
-
-
Wang, Q.1
Curran, M.E.2
Splawski, I.3
Burn, T.C.4
Millholland, J.M.5
-
16
-
-
0031054075
-
A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome
-
Neyroud N, Tesson F, Denjoy I, Leibovici M, Donger C, et al. (1997) A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome. Nat Genet 15: 186-189.
-
(1997)
Nat Genet
, vol.15
, pp. 186-189
-
-
Neyroud, N.1
Tesson, F.2
Denjoy, I.3
Leibovici, M.4
Donger, C.5
-
17
-
-
29844437655
-
International union of pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
-
Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, et al. (2005) International union of pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol Rev 57: 473-508.
-
(2005)
Pharmacol Rev
, vol.57
, pp. 473-508
-
-
Gutman, G.A.1
Chandy, K.G.2
Grissmer, S.3
Lazdunski, M.4
McKinnon, D.5
-
18
-
-
59249088421
-
SNAP-25 (1-180) enhances insulin secretion by blocking Kv2.1 channels in rat pancreatic islet beta-cells
-
Zhuang GQ, Wu W, Liu F, Ma JL, Luo YX, et al. (2009) SNAP-25 (1-180) enhances insulin secretion by blocking Kv2.1 channels in rat pancreatic islet beta-cells. Biochem Biophys Res Commun 379: 812-816.
-
(2009)
Biochem Biophys Res Commun
, vol.379
, pp. 812-816
-
-
Zhuang, G.Q.1
Wu, W.2
Liu, F.3
Ma, J.L.4
Luo, Y.X.5
-
19
-
-
35348946444
-
SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins
-
Leung YM, Kwan EP, Ng B, Kang Y, Gaisano HY, (2007) SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins. Endocr Rev 28: 653-663.
-
(2007)
Endocr Rev
, vol.28
, pp. 653-663
-
-
Leung, Y.M.1
Kwan, E.P.2
Ng, B.3
Kang, Y.4
Gaisano, H.Y.5
-
20
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
Alberti KG, Zimmet PZ, (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15: 539-553.
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
21
-
-
70549111807
-
Evaluation of proposed oral disposition index measures in relation to the actual disposition index
-
Retnakaran R, Qi Y, Goran MI, Hamilton JK, (2009) Evaluation of proposed oral disposition index measures in relation to the actual disposition index. Diabet Med 26: 1198-1203.
-
(2009)
Diabet Med
, vol.26
, pp. 1198-1203
-
-
Retnakaran, R.1
Qi, Y.2
Goran, M.I.3
Hamilton, J.K.4
-
22
-
-
23844541276
-
Biophysical and pharmacological properties of the voltage-gated potassium current of human pancreatic beta-cells
-
Herrington J, Sanchez M, Wunderler D, Yan L, Bugianesi RM, et al. (2005) Biophysical and pharmacological properties of the voltage-gated potassium current of human pancreatic beta-cells. J Physiol 567: 159-175.
-
(2005)
J Physiol
, vol.567
, pp. 159-175
-
-
Herrington, J.1
Sanchez, M.2
Wunderler, D.3
Yan, L.4
Bugianesi, R.M.5
-
23
-
-
79953001206
-
Sialic acids attached to O-glycans modulate voltage-gated potassium channel gating
-
Schwetz TA, Norring SA, Ednie AR, Bennett ES, (2010) Sialic acids attached to O-glycans modulate voltage-gated potassium channel gating. J Biol Chem 286: 4123-4132.
-
(2010)
J Biol Chem
, vol.286
, pp. 4123-4132
-
-
Schwetz, T.A.1
Norring, S.A.2
Ednie, A.R.3
Bennett, E.S.4
-
24
-
-
58549113187
-
Voltage-gated potassium channel as a facilitator of exocytosis
-
Feinshreiber L, Singer-Lahat D, Ashery U, Lotan I, (2009) Voltage-gated potassium channel as a facilitator of exocytosis. Ann N Y Acad Sci 1152: 87-92.
-
(2009)
Ann N Y Acad Sci
, vol.1152
, pp. 87-92
-
-
Feinshreiber, L.1
Singer-Lahat, D.2
Ashery, U.3
Lotan, I.4
-
25
-
-
77953150794
-
Non-conducting function of the Kv2.1 channel enables it to recruit vesicles for release in neuroendocrine and nerve cells
-
Feinshreiber L, Singer-Lahat D, Friedrich R, Matti U, Sheinin A, et al. (2010) Non-conducting function of the Kv2.1 channel enables it to recruit vesicles for release in neuroendocrine and nerve cells. J Cell Sci 123: 1940-1947.
-
(2010)
J Cell Sci
, vol.123
, pp. 1940-1947
-
-
Feinshreiber, L.1
Singer-Lahat, D.2
Friedrich, R.3
Matti, U.4
Sheinin, A.5
-
26
-
-
0347995064
-
Human adipose cells have voltage-dependent potassium currents
-
Ramiez-Ponce MP, Mateos JC, Bellido JA, (2003) Human adipose cells have voltage-dependent potassium currents. J Membr Biol 196: 129-134.
-
(2003)
J Membr Biol
, vol.196
, pp. 129-134
-
-
Ramiez-Ponce, M.P.1
Mateos, J.C.2
Bellido, J.A.3
-
27
-
-
0036687867
-
Insulin increases the density of potassium channels in white adipocytes: possible role in adipogenesis
-
Ramírez-Ponce MP, Mateos JC, Bellido JA, (2002) Insulin increases the density of potassium channels in white adipocytes: possible role in adipogenesis. J Endocrinol 174: 299-307.
-
(2002)
J Endocrinol
, vol.174
, pp. 299-307
-
-
Ramírez-Ponce, M.P.1
Mateos, J.C.2
Bellido, J.A.3
-
28
-
-
71249125848
-
Association of KCNB1 to rheumatoid arthritis via interaction with HLA-DRB1
-
Xiao X, Zhang Y, Wang K, (2009) Association of KCNB1 to rheumatoid arthritis via interaction with HLA-DRB1. BMC Proc 3 (Suppl 7): S134.
-
(2009)
BMC Proc
, vol.3
, Issue.SUPPL. 7
-
-
Xiao, X.1
Zhang, Y.2
Wang, K.3
|