Polymorphisms in the gene encoding the voltage-dependent Ca2+ channel CaV2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion

Diabetologia

Volumn 50, Issue 12, 2007, Pages 2467-2475

  Holmkvist, J ^a   Tojjar, D ^a   Almgren, P ^a   Lyssenko, V ^a   Lindgren, C M ^b,c   Isomaa, B ^d,e   Tuomi, T ^e,f   Berglund, G ^a   Renstrom E ^a   Groop, L ^a,f  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c KAROLINSKA INSTITUTE   (Sweden)

^d Malmska Municipal Health Care Center and Hospital   (Finland)

^e FOLKHÄLSAN RESEARCH CENTER   (Finland)

^f HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Association; CACNA1E; Insulin; Insulin secretion; Single nucleotide polymorphism; SNP; Voltage dependent Ca2+ channel CaV2.3

Indexed keywords

CALCIUM CHANNEL; GLUCOSE; INSULIN; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT CALCIUM CHANNEL CAV2.3;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GLUCOSE METABOLISM; HAPLOTYPE; HUMAN; INSULIN RELEASE; INTRAVENOUS GLUCOSE TOLERANCE TEST; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POPULATION RESEARCH; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TELOMERE;

ADOLESCENT; ADULT; AGED; CALCIUM CHANNELS, R-TYPE; CASE-CONTROL STUDIES; CATION TRANSPORT PROTEINS; DIABETES MELLITUS, TYPE 2; FEMALE; GENOTYPE; HUMANS; INSULIN; INSULIN RESISTANCE; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; SWEDEN;

EID: 35948940879     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-007-0846-2     Document Type: Article

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