메뉴 건너뛰기




Volumn 304, Issue 4, 2013, Pages

Activation of c-SRC underlies the differential effects of ouabain and digoxin on Ca2+ signaling in arterial smooth muscle cells

Author keywords

Cardiotonic steroids; Na+ pumps; NCX1; Receptoroperated Ca2+ entry; TRPC proteins

Indexed keywords

DIGOXIN; OUABAIN; PROTEIN KINASE P60;

EID: 84874091108     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00337.2012     Document Type: Article
Times cited : (46)

References (64)
  • 1
    • 0014038168 scopus 로고
    • Digitalis in the treatment of hypertension. A preliminary report
    • Abarquez RF Jr. Digitalis in the treatment of hypertension. A preliminary report. Acta Med Philipp 3: 161-170, 1967.
    • (1967) Acta Med Philipp , vol.3 , pp. 161-170
    • Abarquez Jr., R.F.1
  • 2
    • 0034627767 scopus 로고    scopus 로고
    • Src family tyrosine kinases and growth factor signaling
    • Abram CL, Courtneidge SA. Src family tyrosine kinases and growth factor signaling. Exp Cell Res 254: 1-13, 2000.
    • (2000) Exp Cell Res , vol.254 , pp. 1-13
    • Abram, C.L.1    Courtneidge, S.A.2
  • 4
    • 33947098988 scopus 로고    scopus 로고
    • Enhancement of receptoroperated cation current and TRPC6 expression in arterial smooth muscle cells of deoxycorticosterone acetate-salt hypertensive rats
    • Bae YM, Kim A, Lee YJ, Lim W, Noh YH, Kim EJ, Kim J, Kim TK, Park SW, Kim B, Cho SI, Kim DK, Ho WK. Enhancement of receptoroperated cation current and TRPC6 expression in arterial smooth muscle cells of deoxycorticosterone acetate-salt hypertensive rats. J Hypertens 25: 809-817, 2007.
    • (2007) J Hypertens , vol.25 , pp. 809-817
    • Bae, Y.M.1    Kim, A.2    Lee, Y.J.3    Lim, W.4    Noh, Y.H.5    Kim, E.J.6    Kim, J.7    Kim, T.K.8    Park, S.W.9    Kim, B.10    Cho, S.I.11    Kim, D.K.12    Ho, W.K.13
  • 5
    • 63849168850 scopus 로고    scopus 로고
    • Endogenous cardiotonic steroids: Physiology, pharmacology, and novel therapeutic targets
    • Bagrov AY, Shapiro JI, Fedorova OV. Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets. Pharmacol Rev 61: 9-38, 2009.
    • (2009) Pharmacol Rev , vol.61 , pp. 9-38
    • Bagrov, A.Y.1    Shapiro, J.I.2    Fedorova, O.V.3
  • 7
    • 4644239523 scopus 로고    scopus 로고
    • Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP
    • Beech DJ, Muraki K, Flemming R. Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP. J Physiol 559: 685-706, 2004.
    • (2004) J Physiol , vol.559 , pp. 685-706
    • Beech, D.J.1    Muraki, K.2    Flemming, R.3
  • 9
    • 84874069206 scopus 로고    scopus 로고
    • How does ouabain, but not digoxin, elevate blood pressure? New insight from studies of ouabain-digoxin interactions in arteries
    • Jerusalem, Israel (Abstract)
    • +-ATPase, Jerusalem, Israel (Abstract), 2011.
    • (2011) +-ATPase
    • Blaustein, M.P.1
  • 10
    • 0017684120 scopus 로고
    • Sodium ions, calcium ions, blood pressure regulation, and hypertension: A reassessment and a hypothesis
    • Blaustein MP. Sodium ions, calcium ions, blood pressure regulation, and hypertension: a reassessment and a hypothesis. Am J Physiol Cell Physiol 232: C165-C173, 1977.
    • (1977) Am J Physiol Cell Physiol , vol.232
    • Blaustein, M.P.1
  • 13
    • 79960382104 scopus 로고    scopus 로고
    • Biased ligands for better cardiovascular drugs: Dissecting G-protein-coupled receptor pharmacology
    • DeWire SM, Violin JD. Biased ligands for better cardiovascular drugs: dissecting G-protein-coupled receptor pharmacology. Circ Res 109: 205-216, 2011.
    • (2011) Circ Res , vol.109 , pp. 205-216
    • DeWire, S.M.1    Violin, J.D.2
  • 14
    • 27644466627 scopus 로고    scopus 로고
    • The highly conserved cardiac glycoside binding site of Na, K-ATPase plays a role in blood pressure regulation
    • Dostanic-Larson I, Van Huysse JW, Lorenz JN, Lingrel JB. The highly conserved cardiac glycoside binding site of Na, K-ATPase plays a role in blood pressure regulation. Proc Natl Acad Sci USA 102: 15845-15850, 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15845-15850
    • Dostanic-Larson, I.1    van Huysse, J.W.2    Lorenz, J.N.3    Lingrel, J.B.4
  • 16
    • 0030828005 scopus 로고    scopus 로고
    • Ouabain-like factor quantification in mammalian tissues and plasma: Comparison of two independent assays
    • Ferrandi M, Manunta P, Balzan S, Hamlyn JM, Bianchi G, Ferrari P. Ouabain-like factor quantification in mammalian tissues and plasma: comparison of two independent assays. Hypertension 30: 886-896, 1997.
    • (1997) Hypertension , vol.30 , pp. 886-896
    • Ferrandi, M.1    Manunta, P.2    Balzan, S.3    Hamlyn, J.M.4    Bianchi, G.5    Ferrari, P.6
  • 17
    • 34548862849 scopus 로고    scopus 로고
    • Preparation of primary cultured mesenteric artery smooth muscle cells for fluorescent imaging and physiological studies
    • Golovina VA, Blaustein MP. Preparation of primary cultured mesenteric artery smooth muscle cells for fluorescent imaging and physiological studies. Nat Protoc 1: 2681-2687, 2006.
    • (2006) Nat Protoc , vol.1 , pp. 2681-2687
    • Golovina, V.A.1    Blaustein, M.P.2
  • 19
    • 0021369834 scopus 로고
    • Effects of digoxin on responsiveness to the pressor actions of angiotensin and norepinephrine in man
    • Guthrie GP Jr. Effects of digoxin on responsiveness to the pressor actions of angiotensin and norepinephrine in man. J Clin Endocrinol Metab 58: 76-80, 1984.
    • (1984) J Clin Endocrinol Metab , vol.58 , pp. 76-80
    • Guthrie Jr., G.P.1
  • 20
    • 0017188515 scopus 로고
    • The role of humoral agents in volume expanded hypertension
    • Haddy FJ, Overbeck HW. The role of humoral agents in volume expanded hypertension. Life Sci 19: 935-947, 1976.
    • (1976) Life Sci , vol.19 , pp. 935-947
    • Haddy, F.J.1    Overbeck, H.W.2
  • 24
    • 0032709861 scopus 로고    scopus 로고
    • Digoxin prevents ouabain and high salt intake-induced hypertension in rats with sinoaortic denervation
    • Huang BS, Kudlac M, Kumarathasan R, Leenen FH. Digoxin prevents ouabain and high salt intake-induced hypertension in rats with sinoaortic denervation. Hypertension 34: 733-738, 1999.
    • (1999) Hypertension , vol.34 , pp. 733-738
    • Huang, B.S.1    Kudlac, M.2    Kumarathasan, R.3    Leenen, F.H.4
  • 26
    • 0033032559 scopus 로고    scopus 로고
    • Effects of digoxin-specific antibody Fab fragment (Digibind) on blood pressure and renal water-sodium metabolism in 5/6 reduced renal mass hypertensive rats
    • Kaide J, Ura N, Torii T, Nakagawa M, Takada T, Shimamoto K. Effects of digoxin-specific antibody Fab fragment (Digibind) on blood pressure and renal water-sodium metabolism in 5/6 reduced renal mass hypertensive rats. Am J Hypertens 12: 611-619, 1999.
    • (1999) Am J Hypertens , vol.12 , pp. 611-619
    • Kaide, J.1    Ura, N.2    Torii, T.3    Nakagawa, M.4    Takada, T.5    Shimamoto, K.6
  • 28
    • 78751498756 scopus 로고    scopus 로고
    • Functional selectivity and biased receptor signaling
    • Kenakin T. Functional selectivity and biased receptor signaling. J Pharmacol Exp Ther 336: 296-302, 2011.
    • (2011) J Pharmacol Exp Ther , vol.336 , pp. 296-302
    • Kenakin, T.1
  • 29
    • 0033801772 scopus 로고    scopus 로고
    • Different effects of in vivo ouabain and digoxin on renal artery function and blood pressure in the rat
    • Kimura K, Manunta P, Hamilton BP, Hamlyn JM. Different effects of in vivo ouabain and digoxin on renal artery function and blood pressure in the rat. Hypertens Res 23, Suppl: S67-S76, 2000.
    • (2000) Hypertens Res , vol.23 , Issue.SUPPL.
    • Kimura, K.1    Manunta, P.2    Hamilton, B.P.3    Hamlyn, J.M.4
  • 30
    • 0029811454 scopus 로고    scopus 로고
    • Chronic sodium potassium-ATPase inhibition with ouabain impairs renal haemodynamics and pressure natriuresis in the rat
    • Kurashina T, Kirchner KA, Granger JP, Patel AR. Chronic sodium potassium-ATPase inhibition with ouabain impairs renal haemodynamics and pressure natriuresis in the rat. Clin Sci (Lond) 91: 497-502, 1996.
    • (1996) Clin Sci (Lond) , vol.91 , pp. 497-502
    • Kurashina, T.1    Kirchner, K.A.2    Granger, J.P.3    Patel, A.R.4
  • 31
    • 0025157183 scopus 로고
    • 2+ of agonist-stimulated divalent cation entry from the refilling of the agonist sensitive intracellular pool
    • 2+ of agonist-stimulated divalent cation entry from the refilling of the agonist sensitive intracellular pool. J Biol Chem 265: 678-684, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 678-684
    • Kwan, C.Y.1    Putney Jr., J.W.2
  • 32
    • 62149104775 scopus 로고    scopus 로고
    • The Na/K-ATPase/Src complex and cardiotonic steroidactivated protein kinase cascades
    • Li Z, Xie Z. The Na/K-ATPase/Src complex and cardiotonic steroidactivated protein kinase cascades. Pflügers Arch 457: 635-644, 2009.
    • (2009) Pflügers Arch , vol.457 , pp. 635-644
    • Li, Z.1    Xie, Z.2
  • 33
    • 33745864301 scopus 로고    scopus 로고
    • Functional characterization of Src interacting Na/K-ATPase using RNA interference assay
    • Liang M, Cai T, Tian J, Qu W, Xie ZJ. Functional characterization of Src interacting Na/K-ATPase using RNA interference assay. J Biol Chem 281: 19709-19719, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 19709-19719
    • Liang, M.1    Cai, T.2    Tian, J.3    Qu, W.4    Xie, Z.J.5
  • 35
    • 78049262472 scopus 로고    scopus 로고
    • The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking
    • Liu J, Xie ZJ. The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking. Biochim Biophys Acta 1802: 1237-1245, 2010.
    • (2010) Biochim Biophys Acta , vol.1802 , pp. 1237-1245
    • Liu, J.1    Xie, Z.J.2
  • 38
    • 58849148597 scopus 로고    scopus 로고
    • Endogenous ouabain in cardiovascular function and disease
    • Manunta P, Ferrandi M, Bianchi G, Hamlyn JM. Endogenous ouabain in cardiovascular function and disease. J Hypertens 27: 9-18, 2009.
    • (2009) J Hypertens , vol.27 , pp. 9-18
    • Manunta, P.1    Ferrandi, M.2    Bianchi, G.3    Hamlyn, J.M.4
  • 39
    • 0033799448 scopus 로고    scopus 로고
    • Chronic hypertension induced by ouabain but not digoxin in the rat: Antihypertensive effect of digoxin and digitoxin
    • Manunta P, Hamilton J, Rogowski AC, Hamilton BP, Hamlyn JM. Chronic hypertension induced by ouabain but not digoxin in the rat: antihypertensive effect of digoxin and digitoxin. Hypertens Res 23, Suppl: S77-S85, 2000.
    • (2000) Hypertens Res , vol.23 , Issue.SUPPL.
    • Manunta, P.1    Hamilton, J.2    Rogowski, A.C.3    Hamilton, B.P.4    Hamlyn, J.M.5
  • 40
    • 0028271160 scopus 로고
    • Ouabaininduced hypertension in the rat: Relationships among plasma and tissue ouabain and blood pressure
    • Manunta P, Rogowski AC, Hamilton BP, Hamlyn JM. Ouabaininduced hypertension in the rat: relationships among plasma and tissue ouabain and blood pressure. J Hypertens 12: 549-560, 1994.
    • (1994) J Hypertens , vol.12 , pp. 549-560
    • Manunta, P.1    Rogowski, A.C.2    Hamilton, B.P.3    Hamlyn, J.M.4
  • 41
    • 8544278506 scopus 로고
    • Effects of cardiac glycoside on vascular system
    • In, edited by Greef F. New York: Springer
    • Mason DT. Effects of cardiac glycoside on vascular system. In: Cardiac Glycosides. Part 1: Experimental Pharmacology, edited by Greef F. New York: Springer, 1981 p. 497-515.
    • (1981) Cardiac Glycosides. Part 1: Experimental Pharmacology , pp. 497-515
    • Mason, D.T.1
  • 42
    • 0025604929 scopus 로고
    • +)-ATPase isozymes for cardioactive steroids, role of lactone ring, sugar moiety and KCl concentration
    • +)-ATPase isozymes for cardioactive steroids, role of lactone ring, sugar moiety and KCl concentration. Biochem Pharmacol 40: 2611-2616, 1990.
    • (1990) Biochem Pharmacol , vol.40 , pp. 2611-2616
    • Noel, F.1    Fagoo, M.2    Godfraind, T.3
  • 43
    • 0028334076 scopus 로고
    • Ouabain binding kinetics of the rat alpha two and alpha three isoforms of the sodium-potassium adenosine triphosphate
    • O'Brien WJ, Lingrel JB, Wallick ET. Ouabain binding kinetics of the rat alpha two and alpha three isoforms of the sodium-potassium adenosine triphosphate. Arch Biochem Biophys 310: 32-39, 1994.
    • (1994) Arch Biochem Biophys , vol.310 , pp. 32-39
    • O'Brien, W.J.1    Lingrel, J.B.2    Wallick, E.T.3
  • 47
    • 77952624088 scopus 로고    scopus 로고
    • Sympathetic nerves and endothelium influence the vasoconstrictor effect of low concentrations of ouabain in pressurized small arteries
    • Raina H, Zhang Q, Rhee AY, Pallone TL, Wier WG. Sympathetic nerves and endothelium influence the vasoconstrictor effect of low concentrations of ouabain in pressurized small arteries. Am J Physiol Heart Circ Physiol 298: H2093-H2101, 2010.
    • (2010) Am J Physiol Heart Circ Physiol , vol.298
    • Raina, H.1    Zhang, Q.2    Rhee, A.Y.3    Pallone, T.L.4    Wier, W.G.5
  • 48
    • 0028788618 scopus 로고
    • Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: Relationship with plasma renin, aldosterone and blood pressure levels
    • Rossi G, Manunta P, Hamlyn JM, Pavan E, De Toni R, Semplicini A, Pessina AC. Immunoreactive endogenous ouabain in primary aldosteronism and essential hypertension: relationship with plasma renin, aldosterone and blood pressure levels. J Hypertens 13: 1181-1191, 1995.
    • (1995) J Hypertens , vol.13 , pp. 1181-1191
    • Rossi, G.1    Manunta, P.2    Hamlyn, J.M.3    Pavan, E.4    de Toni, R.5    Semplicini, A.6    Pessina, A.C.7
  • 49
    • 34547733409 scopus 로고    scopus 로고
    • Endogenous and exogenous cardiac glycosides: Their roles in hypertension, salt metabolism, and cell growth
    • Schoner W, Scheiner-Bobis G. Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth. Am J Physiol Cell Physiol 293: C509-C536, 2007.
    • (2007) Am J Physiol Cell Physiol , vol.293
    • Schoner, W.1    Scheiner-Bobis, G.2
  • 50
    • 0023601901 scopus 로고
    • Ouabain-induced elevation in forearm vascular resistance, calcium entry and alpha-adrenoceptor blockade, and release and removal of noradrenaline
    • Schulte KL, van Gemmeren D, Thiede HM, Meyer-Sabellek W, Gotzen R, Distler A. Ouabain-induced elevation in forearm vascular resistance, calcium entry and alpha-adrenoceptor blockade, and release and removal of noradrenaline. J Hypertens Suppl 5: S215-S218, 1987.
    • (1987) J Hypertens Suppl , vol.5
    • Schulte, K.L.1    van Gemmeren, D.2    Thiede, H.M.3    Meyer-Sabellek, W.4    Gotzen, R.5    Distler, A.6
  • 54
    • 4644314868 scopus 로고    scopus 로고
    • Obligatory role of Src kinase in the signaling mechanism for TRPC3 cation channels
    • Vazquez G, Wedel BJ, Kawasaki BT, Bird GS, Putney JW Jr. Obligatory role of Src kinase in the signaling mechanism for TRPC3 cation channels. J Biol Chem 279: 40521-40528, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 40521-40528
    • Vazquez, G.1    Wedel, B.J.2    Kawasaki, B.T.3    Bird, G.S.4    Putney Jr., J.W.5
  • 57
    • 0037155047 scopus 로고    scopus 로고
    • Transient receptor potential channels regulate myogenic tone of resistance arteries
    • Welsh DG, Morielli AD, Nelson MT, Brayden JE. Transient receptor potential channels regulate myogenic tone of resistance arteries. Circ Res 90: 248-250, 2002.
    • (2002) Circ Res , vol.90 , pp. 248-250
    • Welsh, D.G.1    Morielli, A.D.2    Nelson, M.T.3    Brayden, J.E.4
  • 60
    • 0016378064 scopus 로고
    • Association and dissociation rate constants of the complexes between various cardiac monoglycosides and Na, K-ATPase
    • Yoda A. Association and dissociation rate constants of the complexes between various cardiac monoglycosides and Na, K-ATPase. Ann NY Acad Sci 242: 598-616, 1974.
    • (1974) Ann NY Acad Sci , vol.242 , pp. 598-616
    • Yoda, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.