메뉴 건너뛰기




Volumn 61, Issue 7, 2013, Pages 1525-1533

Different phenolic compounds activate distinct human bitter taste receptors

Author keywords

bitterness; polyphenols; tannins

Indexed keywords

BITTERNESS; CHEMOPREVENTIVE; CONDENSED TANNINS; DERIVED PRODUCTS; EPICATECHIN; GALLOYL GROUP; HIGH POTENCY; HYDROLYZABLE TANNINS; LOW CONCENTRATIONS; PHENOLIC COMPOUNDS; POLYPHENOLS; PROCYANIDINS; RED WINE; SENSORY ATTRIBUTES; STRUCTURAL DETERMINANTS; TASTE RECEPTORS;

EID: 84874078724     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf304198k     Document Type: Article
Times cited : (223)

References (44)
  • 1
    • 33749246068 scopus 로고    scopus 로고
    • Endothelial function and cardiovascular disease: Effects of quercetin and wine polyphenols
    • Perez-Vizcaino, F.; Duarte, J.; Andriantsitohaina, R. Endothelial function and cardiovascular disease: effects of quercetin and wine polyphenols Free Radical Res. 2006, 40, 1054-1065
    • (2006) Free Radical Res. , vol.40 , pp. 1054-1065
    • Perez-Vizcaino, F.1    Duarte, J.2    Andriantsitohaina, R.3
  • 2
    • 0033667684 scopus 로고    scopus 로고
    • Bitter taste, phytonutrients, and the consumer: A review
    • Drewnowski, A.; Gomez-Carneros, C. Bitter taste, phytonutrients, and the consumer: a review Am. J. Clin. Nutr. 2000, 72, 1424-1435
    • (2000) Am. J. Clin. Nutr. , vol.72 , pp. 1424-1435
    • Drewnowski, A.1    Gomez-Carneros, C.2
  • 3
    • 54349099301 scopus 로고    scopus 로고
    • Quantitative reconstruction of the nonvolatile sensometabolome of a red wine
    • Hufnagel, J. C.; Hofmann, T. Quantitative reconstruction of the nonvolatile sensometabolome of a red wine J. Agric. Food Chem. 2008, 56, 9190-9199
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 9190-9199
    • Hufnagel, J.C.1    Hofmann, T.2
  • 4
    • 0033003465 scopus 로고    scopus 로고
    • Bitterness and astringency of flavan-3-ol monomers, dimers and trimers
    • Peleg, H.; Gacon, K.; Schlich, P.; Noble, A. C. Bitterness and astringency of flavan-3-ol monomers, dimers and trimers J. Sci. Food Agric. 1999, 79, 1123-1128
    • (1999) J. Sci. Food Agric. , vol.79 , pp. 1123-1128
    • Peleg, H.1    Gacon, K.2    Schlich, P.3    Noble, A.C.4
  • 5
    • 0000678959 scopus 로고
    • Bitterness and astringency of phenolic fractions in wine
    • Arnold, R. A.; Noble, A. C.; Singleton, V. L. Bitterness and astringency of phenolic fractions in wine J. Agric. Food Chem. 1980, 28, 675-678
    • (1980) J. Agric. Food Chem. , vol.28 , pp. 675-678
    • Arnold, R.A.1    Noble, A.C.2    Singleton, V.L.3
  • 6
    • 84986857942 scopus 로고
    • Astringency and bitterness of selected phenolics in wine
    • Robichaud, J. L.; Noble, A. C. Astringency and bitterness of selected phenolics in wine J. Sci. Food Agric. 1990, 52, 343-353
    • (1990) J. Sci. Food Agric. , vol.52 , pp. 343-353
    • Robichaud, J.L.1    Noble, A.C.2
  • 7
    • 0031497544 scopus 로고    scopus 로고
    • Evaluation of bitterness and astringency of (+)-catechin and (-)-epicatechin in red wine and in model solution
    • Kallithraka, S.; Bakker, J. Evaluation of bitterness and astringency of (+)-catechin and (-)-epicatechin in red wine and in model solution J. Sens. Stud. 1997, 12, 25-37
    • (1997) J. Sens. Stud. , vol.12 , pp. 25-37
    • Kallithraka, S.1    Bakker, J.2
  • 8
    • 84986782894 scopus 로고
    • The phenolics of ciders: Bitterness and astringency
    • Lea, A. G. H.; Arnold, G. M. The phenolics of ciders: bitterness and astringency J. Sci. Food Agric. 1978, 29, 478-483
    • (1978) J. Sci. Food Agric. , vol.29 , pp. 478-483
    • Lea, A.G.H.1    Arnold, G.M.2
  • 9
    • 0034611738 scopus 로고    scopus 로고
    • A family of candidate taste receptors in human and mouse
    • Matsunami, H.; Montmayeur, J. P.; Buck, L. B. A family of candidate taste receptors in human and mouse Nature 2000, 404, 601-604
    • (2000) Nature , vol.404 , pp. 601-604
    • Matsunami, H.1    Montmayeur, J.P.2    Buck, L.B.3
  • 12
    • 0036844351 scopus 로고    scopus 로고
    • The human TAS2R16 receptor mediates bitter taste in response to β-glucopyranosides
    • Bufe, B.; Hofmann, T.; Krautwurst, D.; Raguse, J. D.; Meyerhof, W. The human TAS2R16 receptor mediates bitter taste in response to β- glucopyranosides Nat. Genet. 2002, 32, 397-401
    • (2002) Nat. Genet. , vol.32 , pp. 397-401
    • Bufe, B.1    Hofmann, T.2    Krautwurst, D.3    Raguse, J.D.4    Meyerhof, W.5
  • 15
    • 13944250257 scopus 로고    scopus 로고
    • The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception
    • Bufe, B.; Breslin, P. A. S.; Kuhn, C.; Reed, D. R.; Tharp, C. D.; Slack, J. P.; Kim, U. K.; Drayna, D.; Meyerhof, W. The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception Curr. Biol. 2005, 15, 322-327
    • (2005) Curr. Biol. , vol.15 , pp. 322-327
    • Bufe, B.1    Breslin, P.A.S.2    Kuhn, C.3    Reed, D.R.4    Tharp, C.D.5    Slack, J.P.6    Kim, U.K.7    Drayna, D.8    Meyerhof, W.9
  • 16
    • 34547858150 scopus 로고    scopus 로고
    • Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin
    • Pronin, A. N.; Xu, H.; Tang, H.; Zhang, L.; Li, Q.; Li, X. Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin Curr. Biol. 2007, 17, 1403-1408
    • (2007) Curr. Biol. , vol.17 , pp. 1403-1408
    • Pronin, A.N.1    Xu, H.2    Tang, H.3    Zhang, L.4    Li, Q.5    Li, X.6
  • 19
    • 70349332600 scopus 로고    scopus 로고
    • Three TAS2R bitter taste receptors mediate the psychophysical responses to bitter compounds of hops (Humulus lupulus l.) and beer
    • Intelmann, D.; Batram, C.; Kuhn, C.; Haseleu, G.; Meyerhof, W.; Hofmann, T. Three TAS2R bitter taste receptors mediate the psychophysical responses to bitter compounds of hops (Humulus lupulus l.) and beer Chemosens. Percept. 2009, 2, 118-132
    • (2009) Chemosens. Percept. , vol.2 , pp. 118-132
    • Intelmann, D.1    Batram, C.2    Kuhn, C.3    Haseleu, G.4    Meyerhof, W.5    Hofmann, T.6
  • 22
    • 24344435450 scopus 로고    scopus 로고
    • Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci
    • Kim, U.; Wooding, S.; Ricci, D.; Jorde, L. B.; Drayna, D. Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci Hum. Mutat. 2005, 26, 199-204
    • (2005) Hum. Mutat. , vol.26 , pp. 199-204
    • Kim, U.1    Wooding, S.2    Ricci, D.3    Jorde, L.B.4    Drayna, D.5
  • 24
    • 80455162686 scopus 로고    scopus 로고
    • Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39
    • Roland, W. S. U.; Vincken, J.-P.; Gouka, R. J.; Van Buren, L.; Gruppen, H.; Smit, G. Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39 J. Agric. Food Chem. 2011, 59, 11764-11771
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 11764-11771
    • Roland, W.S.U.1    Vincken, J.-P.2    Gouka, R.J.3    Van Buren, L.4    Gruppen, H.5    Smit, G.6
  • 26
    • 34250319262 scopus 로고    scopus 로고
    • Distribution, bioactivities and therapeutical potentials of pentagalloylglucopyranose
    • Ren, Y.; Chen, X. Distribution, bioactivities and therapeutical potentials of pentagalloylglucopyranose Curr. Bioact. Compd. 2007, 3, 81-89
    • (2007) Curr. Bioact. Compd. , vol.3 , pp. 81-89
    • Ren, Y.1    Chen, X.2
  • 27
    • 34548051331 scopus 로고    scopus 로고
    • Interaction of different polyphenols with bovine serum albumin (BSA) and human salivary α-amylase (HSA) by fluorescence quenching
    • Soares, S.; Mateus, N.; De Freitas, V. Interaction of different polyphenols with bovine serum albumin (BSA) and human salivary α-amylase (HSA) by fluorescence quenching J. Agric. Food Chem. 2007, 55, 6726-6735
    • (2007) J. Agric. Food Chem. , vol.55 , pp. 6726-6735
    • Soares, S.1    Mateus, N.2    De Freitas, V.3
  • 28
    • 33947322652 scopus 로고    scopus 로고
    • Identification of phenolic compounds isolated from pigmented rices and their aldose reductase inhibitory activities
    • Yawadio, R.; Tanimori, S.; Morita, N. Identification of phenolic compounds isolated from pigmented rices and their aldose reductase inhibitory activities Food Chem. 2007, 101, 1616-1625
    • (2007) Food Chem. , vol.101 , pp. 1616-1625
    • Yawadio, R.1    Tanimori, S.2    Morita, N.3
  • 30
    • 77953906402 scopus 로고    scopus 로고
    • Understanding the binding of procyanidins to pancreatic elastase by experimental and computational methods
    • Bras, N. F.; Goncalves, R.; Fernandes, P. A.; Mateus, N.; Ramos, M. J. O.; De Freitas, V. Understanding the binding of procyanidins to pancreatic elastase by experimental and computational methods Biochemistry 2010, 49, 5097-5108
    • (2010) Biochemistry , vol.49 , pp. 5097-5108
    • Bras, N.F.1    Goncalves, R.2    Fernandes, P.A.3    Mateus, N.4    Ramos, M.J.O.5    De Freitas, V.6
  • 31
    • 37049109841 scopus 로고
    • Synthesis of condensed tannins. Part 9. the condensation sequence of leucocyanidin with (+)-catechin and with the resultant procyanidins
    • Delcour, J. A.; Ferreira, D.; Roux, D. G. Synthesis of condensed tannins. Part 9. The condensation sequence of leucocyanidin with (+)-catechin and with the resultant procyanidins J. Chem. Soc., Perkin Trans. 1 1983, 1711-1717
    • (1983) J. Chem. Soc., Perkin Trans. 1 , pp. 1711-1717
    • Delcour, J.A.1    Ferreira, D.2    Roux, D.G.3
  • 32
    • 2942616464 scopus 로고    scopus 로고
    • Characterization of soluble non-covalent complexes between bovine serum albumin and β-1,2,3,4,6-penta- O -galloyl- d -glucopyranose by MALDI-TOF MS
    • Chen, Y.; Hagerman, A. E. Characterization of soluble non-covalent complexes between bovine serum albumin and β-1,2,3,4,6-penta- O -galloyl- d -glucopyranose by MALDI-TOF MS J. Agric. Food Chem. 2004, 52, 4008-4011
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 4008-4011
    • Chen, Y.1    Hagerman, A.E.2
  • 33
  • 34
    • 0042739015 scopus 로고    scopus 로고
    • Functional interaction between T2R taste receptors and g-protein α subunits expressed in taste receptor cells
    • Ueda, T.; Ugawa, S.; Yamamura, H.; Imaizumi, Y.; Shimada, S. Functional interaction between T2R taste receptors and g-protein α subunits expressed in taste receptor cells J. Neurosci. 2003, 23, 7376-7380
    • (2003) J. Neurosci. , vol.23 , pp. 7376-7380
    • Ueda, T.1    Ugawa, S.2    Yamamura, H.3    Imaizumi, Y.4    Shimada, S.5
  • 35
    • 0026651085 scopus 로고
    • Wine, alcohol, platelets, and the french paradox for coronary heart disease
    • Renaud, S.; De Lorgeril, M. Wine, alcohol, platelets, and the french paradox for coronary heart disease Lancet 1992, 339, 1523-1526
    • (1992) Lancet , vol.339 , pp. 1523-1526
    • Renaud, S.1    De Lorgeril, M.2
  • 36
    • 68149161624 scopus 로고    scopus 로고
    • Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose
    • Zhang, J.; Li, L.; Kim, S.-H.; Hagerman, A.; Lü, J. Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose Pharm. Res. 2009, 26, 2066-2080
    • (2009) Pharm. Res. , vol.26 , pp. 2066-2080
    • Zhang, J.1    Li, L.2    Kim, S.-H.3    Hagerman, A.4    Lü, J.5
  • 38
    • 2442459836 scopus 로고    scopus 로고
    • Taste and mouth-feel properties of different types of tannin-like polyphenolic compounds and anthocyanins in wine
    • Vidal, S.; Francis, L.; Noble, A.; Kwiatkowski, M.; Cheynier, V.; Waters, E. Taste and mouth-feel properties of different types of tannin-like polyphenolic compounds and anthocyanins in wine Anal. Chim. Acta 2004, 513, 57-65
    • (2004) Anal. Chim. Acta , vol.513 , pp. 57-65
    • Vidal, S.1    Francis, L.2    Noble, A.3    Kwiatkowski, M.4    Cheynier, V.5    Waters, E.6
  • 39
    • 23044500098 scopus 로고
    • Chemistry of anthocyanin pigments. 2. Kinetic and thermodynamic study of proton transfer, hydration, and tautomeric reactions of malvidin 3-glucoside
    • Brouillard, R.; Delaporte, B. Chemistry of anthocyanin pigments. 2. Kinetic and thermodynamic study of proton transfer, hydration, and tautomeric reactions of malvidin 3-glucoside J. Am. Chem. Soc. 1977, 99, 8461-8468
    • (1977) J. Am. Chem. Soc. , vol.99 , pp. 8461-8468
    • Brouillard, R.1    Delaporte, B.2
  • 41
    • 0036830672 scopus 로고    scopus 로고
    • Development changes of anthocyanins in Vitis vinifera grapes grown in the douro valley and concentration in respective wines
    • Mateus, N.; Machado, J. M.; De Freitas, V. Development changes of anthocyanins in Vitis vinifera grapes grown in the douro valley and concentration in respective wines J. Sci. Food Agric. 2002, 82, 1689-1695
    • (2002) J. Sci. Food Agric. , vol.82 , pp. 1689-1695
    • Mateus, N.1    MacHado, J.M.2    De Freitas, V.3
  • 43
    • 0034658374 scopus 로고    scopus 로고
    • Flavonols, flavones and flavanols - Nature, occurrence and dietary burden
    • Hollman, P. C. H.; Arts, I. C. W. Flavonols, flavones and flavanols-nature, occurrence and dietary burden J. Sci. Food Agric. 2000, 80, 1081-1093
    • (2000) J. Sci. Food Agric. , vol.80 , pp. 1081-1093
    • Hollman, P.C.H.1    Arts, I.C.W.2
  • 44
    • 0001935211 scopus 로고
    • The effect of ethanol, catechin concentration, and pH on sourness and bitterness of wine
    • Fischer, U.; Noble, A. C. The effect of ethanol, catechin concentration, and pH on sourness and bitterness of wine Am. J. Enol. Vitic. 1994, 45, 6-10
    • (1994) Am. J. Enol. Vitic. , vol.45 , pp. 6-10
    • Fischer, U.1    Noble, A.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.