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Volumn 8, Issue 2, 2013, Pages

Targeting Heat Shock Protein 90 for the Treatment of Malignant Pheochromocytoma

Author keywords

[No Author keywords available]

Indexed keywords

GANETESPIB; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; TANESPIMYCIN;

EID: 84874009582     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0056083     Document Type: Article
Times cited : (27)

References (51)
  • 2
    • 84860834761 scopus 로고    scopus 로고
    • An update on the genetics of paraganglioma, pheochromocytoma, and associated hereditary syndromes
    • Gimenez-Roqueplo AP, Dahia PL, Robledo M, (2012) An update on the genetics of paraganglioma, pheochromocytoma, and associated hereditary syndromes. Horm Metab Res 44: 328-333.
    • (2012) Horm Metab Res , vol.44 , pp. 328-333
    • Gimenez-Roqueplo, A.P.1    Dahia, P.L.2    Robledo, M.3
  • 3
    • 21044457115 scopus 로고    scopus 로고
    • Hereditary paraganglioma/pheochromocytoma and inherited succinate dehydrogenase deficiency
    • Favier J, Briere JJ, Strompf L, Amar L, Filali M, et al. (2005) Hereditary paraganglioma/pheochromocytoma and inherited succinate dehydrogenase deficiency. Horm Res 63: 171-179.
    • (2005) Horm Res , vol.63 , pp. 171-179
    • Favier, J.1    Briere, J.J.2    Strompf, L.3    Amar, L.4    Filali, M.5
  • 4
    • 0037422207 scopus 로고    scopus 로고
    • Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas
    • Benn DE, Croxson MS, Tucker K, Bambach CP, Richardson AL, et al. (2003) Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas. Oncogene 22: 1358-1364.
    • (2003) Oncogene , vol.22 , pp. 1358-1364
    • Benn, D.E.1    Croxson, M.S.2    Tucker, K.3    Bambach, C.P.4    Richardson, A.L.5
  • 5
    • 84858706936 scopus 로고    scopus 로고
    • A decade (2001-2010) of genetic testing for pheochromocytoma and paraganglioma
    • Buffet A, Venisse A, Nau V, Roncellin I, Boccio V, et al. (2012) A decade (2001-2010) of genetic testing for pheochromocytoma and paraganglioma. Horm Metab Res 44: 359-366.
    • (2012) Horm Metab Res , vol.44 , pp. 359-366
    • Buffet, A.1    Venisse, A.2    Nau, V.3    Roncellin, I.4    Boccio, V.5
  • 6
    • 84863208321 scopus 로고    scopus 로고
    • Somatic Mutation Analysis of the SDHB, SDHC, SDHD, and RET Genes in the Clinical Assessment of Sporadic and Hereditary Pheochromocytoma
    • Weber A, Hoffmann MM, Neumann HP, Erlic Z (2012) Somatic Mutation Analysis of the SDHB, SDHC, SDHD, and RET Genes in the Clinical Assessment of Sporadic and Hereditary Pheochromocytoma. Horm Cancer.
    • (2012) Horm Cancer
    • Weber, A.1    Hoffmann, M.M.2    Neumann, H.P.3    Erlic, Z.4
  • 7
    • 59749100013 scopus 로고    scopus 로고
    • Use of the tyrosine kinase inhibitor sunitinib in a patient with von Hippel-Lindau disease: targeting angiogenic factors in pheochromocytoma and other von Hippel-Lindau disease-related tumors
    • Jimenez C, Cabanillas ME, Santarpia L, Jonasch E, Kyle KL, et al. (2009) Use of the tyrosine kinase inhibitor sunitinib in a patient with von Hippel-Lindau disease: targeting angiogenic factors in pheochromocytoma and other von Hippel-Lindau disease-related tumors. J Clin Endocrinol Metab 94: 386-391.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 386-391
    • Jimenez, C.1    Cabanillas, M.E.2    Santarpia, L.3    Jonasch, E.4    Kyle, K.L.5
  • 8
    • 84858703793 scopus 로고    scopus 로고
    • Signaling pathways in pheochromocytomas and paragangliomas: prospects for future therapies
    • Nolting S, Grossman AB, (2012) Signaling pathways in pheochromocytomas and paragangliomas: prospects for future therapies. Endocr Pathol 23: 21-33.
    • (2012) Endocr Pathol , vol.23 , pp. 21-33
    • Nolting, S.1    Grossman, A.B.2
  • 9
    • 70350354684 scopus 로고    scopus 로고
    • Novel and evolving therapies in the treatment of malignant phaeochromocytoma: experience with the mTOR inhibitor everolimus (RAD001)
    • Druce MR, Kaltsas GA, Fraenkel M, Gross DJ, Grossman AB, (2009) Novel and evolving therapies in the treatment of malignant phaeochromocytoma: experience with the mTOR inhibitor everolimus (RAD001). Horm Metab Res 41: 697-702.
    • (2009) Horm Metab Res , vol.41 , pp. 697-702
    • Druce, M.R.1    Kaltsas, G.A.2    Fraenkel, M.3    Gross, D.J.4    Grossman, A.B.5
  • 10
    • 77953916528 scopus 로고    scopus 로고
    • HSP90 at the hub of protein homeostasis: emerging mechanistic insights
    • Taipale M, Jarosz DF, Lindquist S, (2010) HSP90 at the hub of protein homeostasis: emerging mechanistic insights. Nat Rev Mol Cell Biol 11: 515-528.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 515-528
    • Taipale, M.1    Jarosz, D.F.2    Lindquist, S.3
  • 12
    • 0141787950 scopus 로고    scopus 로고
    • Expression profile of the telomeric complex discriminates between benign and malignant pheochromocytoma
    • Boltze C, Mundschenk J, Unger N, Schneider-Stock R, Peters B, et al. (2003) Expression profile of the telomeric complex discriminates between benign and malignant pheochromocytoma. J Clin Endocrinol Metab 88: 4280-4286.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4280-4286
    • Boltze, C.1    Mundschenk, J.2    Unger, N.3    Schneider-Stock, R.4    Peters, B.5
  • 13
    • 79961046323 scopus 로고    scopus 로고
    • Phaeochromocytoma: a catecholamine and oxidative stress disorder
    • Pacak K, (2011) Phaeochromocytoma: a catecholamine and oxidative stress disorder. Endocr Regul 45: 65-90.
    • (2011) Endocr Regul , vol.45 , pp. 65-90
    • Pacak, K.1
  • 14
    • 79954484756 scopus 로고    scopus 로고
    • Changing paradigms in the treatment of malignant pheochromocytoma
    • Grogan RH, Mitmaker EJ, Duh QY, (2011) Changing paradigms in the treatment of malignant pheochromocytoma. Cancer Control 18: 104-112.
    • (2011) Cancer Control , vol.18 , pp. 104-112
    • Grogan, R.H.1    Mitmaker, E.J.2    Duh, Q.Y.3
  • 16
    • 84857039457 scopus 로고    scopus 로고
    • Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers
    • Jhaveri K, Taldone T, Modi S, Chiosis G, (2012) Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers. Biochim Biophys Acta 1823: 742-755.
    • (2012) Biochim Biophys Acta , vol.1823 , pp. 742-755
    • Jhaveri, K.1    Taldone, T.2    Modi, S.3    Chiosis, G.4
  • 17
    • 62149135294 scopus 로고    scopus 로고
    • Discovery and development of heat shock protein 90 inhibitors
    • Taldone T, Sun W, Chiosis G, (2009) Discovery and development of heat shock protein 90 inhibitors. Bioorg Med Chem 17: 2225-2235.
    • (2009) Bioorg Med Chem , vol.17 , pp. 2225-2235
    • Taldone, T.1    Sun, W.2    Chiosis, G.3
  • 18
    • 84855457952 scopus 로고    scopus 로고
    • Hsp90 molecular chaperone inhibitors: are we there yet?
    • Neckers L, Workman P, (2012) Hsp90 molecular chaperone inhibitors: are we there yet? Clin Cancer Res 18: 64-76.
    • (2012) Clin Cancer Res , vol.18 , pp. 64-76
    • Neckers, L.1    Workman, P.2
  • 19
    • 79952752856 scopus 로고    scopus 로고
    • STA-9090, a small-molecule Hsp90 inhibitor for the potential treatment of cancer
    • Wang Y, Trepel JB, Neckers LM, Giaccone G, (2010) STA-9090, a small-molecule Hsp90 inhibitor for the potential treatment of cancer. Curr Opin Investig Drugs 11: 1466-1476.
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 1466-1476
    • Wang, Y.1    Trepel, J.B.2    Neckers, L.M.3    Giaccone, G.4
  • 20
    • 84856832510 scopus 로고    scopus 로고
    • Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy
    • Ying W, Du Z, Sun L, Foley KP, Proia DA, et al. (2012) Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy. Mol Cancer Ther 11: 475-484.
    • (2012) Mol Cancer Ther , vol.11 , pp. 475-484
    • Ying, W.1    Du, Z.2    Sun, L.3    Foley, K.P.4    Proia, D.A.5
  • 21
    • 79955044159 scopus 로고    scopus 로고
    • Multifaceted intervention by the Hsp90 inhibitor ganetespib (STA-9090) in cancer cells with activated JAK/STAT signaling
    • Proia DA, Foley KP, Korbut T, Sang J, Smith D, et al. (2011) Multifaceted intervention by the Hsp90 inhibitor ganetespib (STA-9090) in cancer cells with activated JAK/STAT signaling. PLoS One 6: e18552.
    • (2011) PLoS One , vol.6
    • Proia, D.A.1    Foley, K.P.2    Korbut, T.3    Sang, J.4    Smith, D.5
  • 22
    • 84855351116 scopus 로고    scopus 로고
    • Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging
    • Giubellino A, Woldemichael GM, Sourbier C, Lizak MJ, Powers JF, et al. (2012) Characterization of two mouse models of metastatic pheochromocytoma using bioluminescence imaging. Cancer Lett 316: 46-52.
    • (2012) Cancer Lett , vol.316 , pp. 46-52
    • Giubellino, A.1    Woldemichael, G.M.2    Sourbier, C.3    Lizak, M.J.4    Powers, J.F.5
  • 23
    • 0033674787 scopus 로고    scopus 로고
    • Pheochromocytoma cell lines from heterozygous neurofibromatosis knockout mice
    • Powers JF, Evinger MJ, Tsokas P, Bedri S, Alroy J, et al. (2000) Pheochromocytoma cell lines from heterozygous neurofibromatosis knockout mice. Cell Tissue Res 302: 309-320.
    • (2000) Cell Tissue Res , vol.302 , pp. 309-320
    • Powers, J.F.1    Evinger, M.J.2    Tsokas, P.3    Bedri, S.4    Alroy, J.5
  • 24
    • 61449213031 scopus 로고    scopus 로고
    • Characterization of an animal model of aggressive metastatic pheochromocytoma linked to a specific gene signature
    • Martiniova L, Lai EW, Elkahloun AG, Abu-Asab M, Wickremasinghe A, et al. (2009) Characterization of an animal model of aggressive metastatic pheochromocytoma linked to a specific gene signature. Clin Exp Metastasis 26: 239-250.
    • (2009) Clin Exp Metastasis , vol.26 , pp. 239-250
    • Martiniova, L.1    Lai, E.W.2    Elkahloun, A.G.3    Abu-Asab, M.4    Wickremasinghe, A.5
  • 25
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene LA, Tischler AS, (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A 73: 2424-2428.
    • (1976) Proc Natl Acad Sci U S A , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 26
    • 0037119415 scopus 로고    scopus 로고
    • Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway
    • Isaacs JS, Jung YJ, Mimnaugh EG, Martinez A, Cuttitta F, et al. (2002) Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway. J Biol Chem 277: 29936-29944.
    • (2002) J Biol Chem , vol.277 , pp. 29936-29944
    • Isaacs, J.S.1    Jung, Y.J.2    Mimnaugh, E.G.3    Martinez, A.4    Cuttitta, F.5
  • 27
    • 0032555685 scopus 로고    scopus 로고
    • Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1
    • Zou J, Guo Y, Guettouche T, Smith DF, Voellmy R, (1998) Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1. Cell 94: 471-480.
    • (1998) Cell , vol.94 , pp. 471-480
    • Zou, J.1    Guo, Y.2    Guettouche, T.3    Smith, D.F.4    Voellmy, R.5
  • 28
    • 33745086222 scopus 로고    scopus 로고
    • Identification of new biomarkers for clinical trials of Hsp90 inhibitors
    • Zhang H, Chung D, Yang YC, Neely L, Tsurumoto S, et al. (2006) Identification of new biomarkers for clinical trials of Hsp90 inhibitors. Mol Cancer Ther 5: 1256-1264.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1256-1264
    • Zhang, H.1    Chung, D.2    Yang, Y.C.3    Neely, L.4    Tsurumoto, S.5
  • 29
    • 36849055007 scopus 로고    scopus 로고
    • Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: a phase I dose-escalation study
    • Modi S, Stopeck AT, Gordon MS, Mendelson D, Solit DB, et al. (2007) Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: a phase I dose-escalation study. J Clin Oncol 25: 5410-5417.
    • (2007) J Clin Oncol , vol.25 , pp. 5410-5417
    • Modi, S.1    Stopeck, A.T.2    Gordon, M.S.3    Mendelson, D.4    Solit, D.B.5
  • 31
    • 84858709007 scopus 로고    scopus 로고
    • From transcriptional profiling to tumor biology in pheochromocytoma and paraganglioma
    • Cascon A, Tennant DA, (2012) From transcriptional profiling to tumor biology in pheochromocytoma and paraganglioma. Endocr Pathol 23: 15-20.
    • (2012) Endocr Pathol , vol.23 , pp. 15-20
    • Cascon, A.1    Tennant, D.A.2
  • 32
    • 54549113030 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer
    • Kaelin WG Jr, (2008) The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer. Nat Rev Cancer 8: 865-873.
    • (2008) Nat Rev Cancer , vol.8 , pp. 865-873
    • Kaelin Jr., W.G.1
  • 33
    • 41649116940 scopus 로고    scopus 로고
    • The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor
    • Schlisio S, Kenchappa RS, Vredeveld LC, George RE, Stewart R, et al. (2008) The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor. Genes Dev 22: 884-893.
    • (2008) Genes Dev , vol.22 , pp. 884-893
    • Schlisio, S.1    Kenchappa, R.S.2    Vredeveld, L.C.3    George, R.E.4    Stewart, R.5
  • 34
    • 84858705282 scopus 로고    scopus 로고
    • Rationale for anti-angiogenic therapy in pheochromocytoma and paraganglioma
    • Favier J, Igaz P, Burnichon N, Amar L, Libe R, et al. (2012) Rationale for anti-angiogenic therapy in pheochromocytoma and paraganglioma. Endocr Pathol 23: 34-42.
    • (2012) Endocr Pathol , vol.23 , pp. 34-42
    • Favier, J.1    Igaz, P.2    Burnichon, N.3    Amar, L.4    Libe, R.5
  • 37
    • 0036792605 scopus 로고    scopus 로고
    • Angiogenesis and vascular architecture in pheochromocytomas: distinctive traits in malignant tumors
    • Favier J, Plouin PF, Corvol P, Gasc JM, (2002) Angiogenesis and vascular architecture in pheochromocytomas: distinctive traits in malignant tumors. Am J Pathol 161: 1235-1246.
    • (2002) Am J Pathol , vol.161 , pp. 1235-1246
    • Favier, J.1    Plouin, P.F.2    Corvol, P.3    Gasc, J.M.4
  • 39
    • 78649404935 scopus 로고    scopus 로고
    • Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas
    • Lopez-Jimenez E, Gomez-Lopez G, Leandro-Garcia LJ, Munoz I, Schiavi F, et al. (2010) Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas. Mol Endocrinol 24: 2382-2391.
    • (2010) Mol Endocrinol , vol.24 , pp. 2382-2391
    • Lopez-Jimenez, E.1    Gomez-Lopez, G.2    Leandro-Garcia, L.J.3    Munoz, I.4    Schiavi, F.5
  • 40
    • 43549102208 scopus 로고    scopus 로고
    • HSP90: the Rosetta stone for cellular protein dynamics?
    • Dezwaan DC, Freeman BC, (2008) HSP90: the Rosetta stone for cellular protein dynamics? Cell Cycle 7: 1006-1012.
    • (2008) Cell Cycle , vol.7 , pp. 1006-1012
    • Dezwaan, D.C.1    Freeman, B.C.2
  • 41
    • 61949212454 scopus 로고    scopus 로고
    • Visualizing the twists and turns of a molecular chaperone
    • Neckers L, Tsutsumi S, Mollapour M, (2009) Visualizing the twists and turns of a molecular chaperone. Nat Struct Mol Biol 16: 235-236.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 235-236
    • Neckers, L.1    Tsutsumi, S.2    Mollapour, M.3
  • 42
    • 65549138976 scopus 로고    scopus 로고
    • The complex dance of the molecular chaperone Hsp90
    • Neckers L, Mollapour M, Tsutsumi S, (2009) The complex dance of the molecular chaperone Hsp90. Trends Biochem Sci 34: 223-226.
    • (2009) Trends Biochem Sci , vol.34 , pp. 223-226
    • Neckers, L.1    Mollapour, M.2    Tsutsumi, S.3
  • 43
    • 0028786332 scopus 로고
    • Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association
    • Schulte TW, Blagosklonny MV, Ingui C, Neckers L, (1995) Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association. J Biol Chem 270: 24585-24588.
    • (1995) J Biol Chem , vol.270 , pp. 24585-24588
    • Schulte, T.W.1    Blagosklonny, M.V.2    Ingui, C.3    Neckers, L.4
  • 44
    • 0037131187 scopus 로고    scopus 로고
    • Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function
    • Basso AD, Solit DB, Chiosis G, Giri B, Tsichlis P, et al. (2002) Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function. J Biol Chem 277: 39858-39866.
    • (2002) J Biol Chem , vol.277 , pp. 39858-39866
    • Basso, A.D.1    Solit, D.B.2    Chiosis, G.3    Giri, B.4    Tsichlis, P.5
  • 45
  • 46
    • 43749107912 scopus 로고    scopus 로고
    • Acquired resistance to tyrosine kinase inhibitors during cancer therapy
    • Engelman JA, Settleman J, (2008) Acquired resistance to tyrosine kinase inhibitors during cancer therapy. Curr Opin Genet Dev 18: 73-79.
    • (2008) Curr Opin Genet Dev , vol.18 , pp. 73-79
    • Engelman, J.A.1    Settleman, J.2
  • 47
    • 34249820803 scopus 로고    scopus 로고
    • Hsp90: a novel target for the disruption of multiple signaling cascades
    • Bishop SC, Burlison JA, Blagg BS, (2007) Hsp90: a novel target for the disruption of multiple signaling cascades. Curr Cancer Drug Targets 7: 369-388.
    • (2007) Curr Cancer Drug Targets , vol.7 , pp. 369-388
    • Bishop, S.C.1    Burlison, J.A.2    Blagg, B.S.3
  • 48
    • 34250162144 scopus 로고    scopus 로고
    • Targeting the molecular chaperone heat shock protein 90 provides a multifaceted effect on diverse cell signaling pathways of cancer cells
    • Xu W, Neckers L, (2007) Targeting the molecular chaperone heat shock protein 90 provides a multifaceted effect on diverse cell signaling pathways of cancer cells. Clin Cancer Res 13: 1625-1629.
    • (2007) Clin Cancer Res , vol.13 , pp. 1625-1629
    • Xu, W.1    Neckers, L.2
  • 49
    • 58849160500 scopus 로고    scopus 로고
    • Heat shock protein 90 as a drug target: some like it hot
    • Banerji U, (2009) Heat shock protein 90 as a drug target: some like it hot. Clin Cancer Res 15: 9-14.
    • (2009) Clin Cancer Res , vol.15 , pp. 9-14
    • Banerji, U.1
  • 50
    • 80455162319 scopus 로고    scopus 로고
    • A phase I study of PF-04929113 (SNX-5422), an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumor malignancies and lymphomas
    • Rajan A, Kelly RJ, Trepel JB, Kim YS, Alarcon SV, et al. (2011) A phase I study of PF-04929113 (SNX-5422), an orally bioavailable heat shock protein 90 inhibitor, in patients with refractory solid tumor malignancies and lymphomas. Clin Cancer Res 17: 6831-6839.
    • (2011) Clin Cancer Res , vol.17 , pp. 6831-6839
    • Rajan, A.1    Kelly, R.J.2    Trepel, J.B.3    Kim, Y.S.4    Alarcon, S.V.5
  • 51
    • 84858701108 scopus 로고    scopus 로고
    • Murine models and cell lines for the investigation of pheochromocytoma: applications for future therapies?
    • Korpershoek E, Pacak K, Martiniova L, (2012) Murine models and cell lines for the investigation of pheochromocytoma: applications for future therapies? Endocr Pathol 23: 43-54.
    • (2012) Endocr Pathol , vol.23 , pp. 43-54
    • Korpershoek, E.1    Pacak, K.2    Martiniova, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.