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Volumn 23, Issue 1, 2012, Pages 15-20

From transcriptional profiling to tumor biology in pheochromocytoma and paraganglioma

Author keywords

MAX; Mutation detection; Paraganglioma; Pheochromocytoma; Pseudohypoxia; Transcriptional regulation

Indexed keywords

CARCINOGENESIS; DISEASE PREDISPOSITION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE MUTATION; GENETIC TRANSCRIPTION; INHERITANCE; NUCLEOTIDE SEQUENCE; PARAGANGLIOMA; PHENOTYPE; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; REVIEW; TRANSCRIPTOMICS; TUMOR; TUMOR BIOLOGY; TUMOR CLASSIFICATION;

EID: 84858709007     PISSN: 10463976     EISSN: 15590097     Source Type: Journal    
DOI: 10.1007/s12022-012-9195-x     Document Type: Review
Times cited : (15)

References (47)
  • 3
    • 33845488766 scopus 로고    scopus 로고
    • Transcriptional regulation of phenylethanolamine N-methyltransferase in pheochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2
    • Huynh, T.T., et al., Transcriptional regulation of phenylethanolamine N-methyltransferase in pheochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2. Ann N Y Acad Sci, 2006. 1073: p. 241-52.
    • (2006) Ann N Y Acad Sci , vol.1073 , pp. 241-252
    • Huynh, T.T.1
  • 4
    • 80053139912 scopus 로고    scopus 로고
    • Integrative genomic analysis reveals somatic mutations in pheochromocytoma and paraganglioma
    • Burnichon, N., et al., Integrative genomic analysis reveals somatic mutations in pheochromocytoma and paraganglioma. Hum Mol Genet, 2011. 20(20): p. 3974-85.
    • (2011) Hum Mol Genet , vol.20 , Issue.20 , pp. 3974-3985
    • Burnichon, N.1
  • 5
    • 78649404935 scopus 로고    scopus 로고
    • Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas
    • Lopez-Jimenez, E., et al., Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas. Mol Endocrinol, 2010. 24(12): p. 2382-91.
    • (2010) Mol Endocrinol , vol.24 , Issue.12 , pp. 2382-2391
    • Lopez-Jimenez, E.1
  • 6
    • 77956357888 scopus 로고    scopus 로고
    • Microarray analysis reveals differential expression of benign and malignant pheochromocytoma
    • Waldmann, J., et al., Microarray analysis reveals differential expression of benign and malignant pheochromocytoma. Endocr Relat Cancer, 2010. 17(3): p. 743-56.
    • (2010) Endocr Relat Cancer , vol.17 , Issue.3 , pp. 743-756
    • Waldmann, J.1
  • 9
    • 77955594623 scopus 로고    scopus 로고
    • A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas
    • Dahia, P.L., et al., A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas. PLoS Genet, 2005. 1(1): p. 72-80.
    • (2005) PLoS Genet , vol.1 , Issue.1 , pp. 72-80
    • Dahia, P.L.1
  • 10
    • 33644551073 scopus 로고    scopus 로고
    • Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers
    • Chi, J.T., et al., Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. PLoS Med, 2006. 3(3): p. e47.
    • (2006) PLoS Med , vol.3 , Issue.3
    • Chi, J.T.1
  • 11
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza, G.L., Targeting HIF-1 for cancer therapy. Nat Rev Cancer, 2003. 3(10): p. 721-32. (Pubitemid 37328811)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.10 , pp. 721-732
    • Semenza, G.L.1
  • 12
    • 0031020884 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
    • Tian, H., S.L. McKnight, and D.W. Russell, Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev, 1997. 11(1): p. 72-82. (Pubitemid 27043825)
    • (1997) Genes and Development , vol.11 , Issue.1 , pp. 72-82
    • Tian, H.1    McKnight, S.L.2    Russell, D.W.3
  • 13
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helixloop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang, G.L., et al., Hypoxia-inducible factor 1 is a basic-helixloop- helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A, 1995. 92(12): p. 5510-4.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.12 , pp. 5510-5514
    • Wang, G.L.1
  • 14
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • DOI 10.1126/science.1066373
    • Bruick, R.K. and S.L. McKnight, A conserved family of prolyl-4-hydroxylases that modify HIF. Science, 2001. 294(5545): p. 1337-40. (Pubitemid 33063099)
    • (2001) Science , vol.294 , Issue.5545 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 17
    • 70349472696 scopus 로고    scopus 로고
    • The Warburg effect is genetically determined in inherited pheochromocytomas
    • Favier, J., et al., The Warburg effect is genetically determined in inherited pheochromocytomas. PLoS One, 2009. 4(9): p. e7094.
    • (2009) PLoS One , vol.4 , Issue.9
    • Favier, J.1
  • 18
    • 28544446058 scopus 로고    scopus 로고
    • Mitochondrial tumour suppressors: A genetic and biochemical update
    • DOI 10.1038/nrc1737
    • Gottlieb, E. and I.P. Tomlinson, Mitochondrial tumour suppressors: a genetic and biochemical update. Nat Rev Cancer, 2005. 5 (11): p. 857-66. (Pubitemid 41746030)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.11 , pp. 857-866
    • Gottlieb, E.1    Tomlinson, I.P.M.2
  • 20
    • 77950342008 scopus 로고    scopus 로고
    • SDHAF2 mutations in familial and sporadic paraganglioma and phaeochromocytoma
    • Bayley, J.P., et al., SDHAF2 mutations in familial and sporadic paraganglioma and phaeochromocytoma. Lancet Oncol, 2010. 11 (4): p. 366-72.
    • (2010) Lancet Oncol , vol.11 , Issue.4 , pp. 366-372
    • Bayley, J.P.1
  • 22
    • 77958164441 scopus 로고    scopus 로고
    • SDHA is a tumor suppressor gene causing paraganglioma
    • Burnichon, N., et al., SDHA is a tumor suppressor gene causing paraganglioma. Hum Mol Genet, 2010. 19(15): p. 3011-20.
    • (2010) Hum Mol Genet , vol.19 , Issue.15 , pp. 3011-3020
    • Burnichon, N.1
  • 23
    • 69549088424 scopus 로고    scopus 로고
    • SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma
    • Hao, H.X., et al., SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. Science, 2009. 325(5944): p. 1139-42.
    • (2009) Science , vol.325 , Issue.5944 , pp. 1139-1142
    • Hao, H.X.1
  • 24
    • 0033767445 scopus 로고    scopus 로고
    • Mutations in SDHC cause autosomal dominant paraganglioma, type 3
    • Niemann, S. and U. Muller, Mutations in SDHC cause autosomal dominant paraganglioma, type 3. Nat Genet, 2000. 26(3): p. 268-70.
    • (2000) Nat Genet , vol.26 , Issue.3 , pp. 268-270
    • Niemann, S.1    Muller, U.2
  • 26
    • 37849022071 scopus 로고    scopus 로고
    • Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxiainducible factor activation and tumorigenesis
    • Guzy, R.D., et al., Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxiainducible factor activation and tumorigenesis. Mol Cell Biol, 2008. 28(2): p. 718-31.
    • (2008) Mol Cell Biol , vol.28 , Issue.2 , pp. 718-731
    • Guzy, R.D.1
  • 27
    • 0037097861 scopus 로고    scopus 로고
    • FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
    • DOI 10.1101/gad.991402
    • Lando, D., et al., FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev, 2002. 16(12): p. 1466-71. (Pubitemid 34686328)
    • (2002) Genes and Development , vol.16 , Issue.12 , pp. 1466-1471
    • Lando, D.1    Peet, D.J.2    Gorman, J.J.3    Whelan, D.A.4    Whitelaw, M.L.5    Bruick, R.K.6
  • 28
    • 0035887011 scopus 로고    scopus 로고
    • FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
    • DOI 10.1101/gad.924501
    • Mahon, P.C., K. Hirota, and G.L. Semenza, FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev, 2001. 15(20): p. 2675-86. (Pubitemid 32988878)
    • (2001) Genes and Development , vol.15 , Issue.20 , pp. 2675-2686
    • Mahon, P.C.1    Hirota, K.2    Semenza, G.L.3
  • 29
    • 40949132841 scopus 로고    scopus 로고
    • Turn me on: Regulating HIF transcriptional activity
    • DOI 10.1038/sj.cdd.4402315, PII 4402315, The biology of Hypoxia-inducible factors
    • Lisy, K. and D.J. Peet, Turn me on: regulating HIF transcriptional activity. Cell Death Differ, 2008. 15(4): p. 642-9. (Pubitemid 351405067)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.4 , pp. 642-649
    • Lisy, K.1    Peet, D.J.2
  • 30
    • 70450239624 scopus 로고    scopus 로고
    • Inhibition of succinate dehydrogenase dysregulates histone modification in mammalian cells
    • Cervera, A.M., et al., Inhibition of succinate dehydrogenase dysregulates histone modification in mammalian cells. Mol Cancer, 2009. 8: p. 89.
    • (2009) Mol Cancer , vol.8 , pp. 89
    • Cervera, A.M.1
  • 32
    • 84863718281 scopus 로고    scopus 로고
    • Loss of the candidate tumor suppressor BTG3 triggers acute cellular senescence via the ERK-JMJD3-p16 (INK4a) signaling axis
    • Lin, T.Y., et al., Loss of the candidate tumor suppressor BTG3 triggers acute cellular senescence via the ERK-JMJD3-p16 (INK4a) signaling axis. Oncogene, 2011.
    • (2011) Oncogene
    • Lin, T.Y.1
  • 33
    • 79953666919 scopus 로고    scopus 로고
    • p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation
    • Sola, S., et al., p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation. PLoS One, 2011. 6(3): p. e18421.
    • (2011) PLoS One , vol.6 , Issue.3
    • Sola, S.1
  • 34
    • 77649175595 scopus 로고    scopus 로고
    • Germline mutations in TMEM127 confer susceptibility to pheochromocytoma
    • Qin, Y., et al., Germline mutations in TMEM127 confer susceptibility to pheochromocytoma. Nat Genet, 2010. 42(3): p. 229-33.
    • (2010) Nat Genet , vol.42 , Issue.3 , pp. 229-233
    • Qin, Y.1
  • 35
    • 0034603172 scopus 로고    scopus 로고
    • Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway
    • DOI 10.1074/jbc.275.5.3568
    • Segouffin-Cariou, C. and M. Billaud, Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway. J Biol Chem, 2000. 275(5): p. 3568-76. (Pubitemid 30083066)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.5 , pp. 3568-3576
    • Segouffin-Cariou, C.1    Billaud, M.2
  • 37
    • 78650200503 scopus 로고    scopus 로고
    • Spectrum and prevalence of FP/TMEM127 gene mutations in pheochromocytomas and paragangliomas
    • Yao, L., et al., Spectrum and prevalence of FP/TMEM127 gene mutations in pheochromocytomas and paragangliomas. JAMA, 2010. 304(23): p. 2611-9.
    • (2010) JAMA , vol.304 , Issue.23 , pp. 2611-2619
    • Yao, L.1
  • 38
    • 44349134920 scopus 로고    scopus 로고
    • Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1
    • DOI 10.1073/pnas.0802785105
    • Zhu, J., J. Blenis, and J. Yuan, Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1. Proc Natl Acad Sci U S A, 2008. 105(18): p. 6584-9. (Pubitemid 351754550)
    • (2008) Proceedings of the National Academy of Sciences of the United States of America , vol.105 , Issue.18 , pp. 6584-6589
    • Zhu, J.1    Blenis, J.2    Yuan, J.3
  • 39
    • 77949347378 scopus 로고    scopus 로고
    • Regulation of gene expression in hepatic cells by the mammalian Target of Rapamycin (mTOR)
    • Jimenez, R.H., et al., Regulation of gene expression in hepatic cells by the mammalian Target of Rapamycin (mTOR). PLoS One, 2010. 5(2): p. e9084.
    • (2010) PLoS One , vol.5 , Issue.2
    • Jimenez, R.H.1
  • 40
    • 0033693018 scopus 로고    scopus 로고
    • Duplication of the mutant RET allele in trisomy 10 or loss of the wild-type allele in multiple endocrine neoplasia type 2-associated pheochromocytomas
    • Huang, S.C., et al., Duplication of the mutant RET allele in trisomy 10 or loss of the wild-type allele in multiple endocrine neoplasia type 2-associated pheochromocytomas. Cancer Res, 2000. 60(22): p. 6223-6.
    • (2000) Cancer Res , vol.60 , Issue.22 , pp. 6223-6226
    • Huang, S.C.1
  • 42
    • 79959752614 scopus 로고    scopus 로고
    • Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma
    • Comino-Mendez, I., et al., Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma. Nat Genet, 2011. 43(7): p. 663-7.
    • (2011) Nat Genet , vol.43 , Issue.7 , pp. 663-667
    • Comino-Mendez, I.1
  • 43
    • 77950193818 scopus 로고    scopus 로고
    • Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression
    • Zhang, X., et al., Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression. Cancer Res, 2010. 70(6): p. 2350-8.
    • (2010) Cancer Res , vol.70 , Issue.6 , pp. 2350-2358
    • Zhang, X.1
  • 45
  • 47
    • 17844397712 scopus 로고    scopus 로고
    • Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors
    • DOI 10.1210/jc.2004-1848
    • Zhao, J., et al., Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors. J Clin Endocrinol Metab, 2005. 90(4): p. 2179-86. (Pubitemid 40586259)
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , Issue.4 , pp. 2179-2186
    • Zhao, J.1    Dahle, D.2    Zhou, Y.3    Zhang, X.4    Klibanski, A.5


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