Pheochromocytoma cell lines from heterozygous neurofibromatosis knockout mice

Cell and Tissue Research

Volumn 302, Issue 3, 2000, Pages 309-320

  Powers, J F ^a   Evinger, M J ^b   Tsokas, P ^a   Bedri, S ^a   Alroy, J ^c   Shahsavari, M ^a   Tischler, A S ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c TUFTS UNIVERSITY   (United States)

Author keywords

Mouse (knockout mutation of NF1); Neurofibromatosis; Neurofibromin; Phenylethanolamine N methylt ransferase; Pheochromocytoma; Silencing; Transcription

Indexed keywords

GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; NEUROFIBROMIN; PHENYLETHANOLAMINE N METHYLTRANSFERASE; RAS PROTEIN;

ALLELE; ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVITY; GENE CONTROL; GENE MUTATION; MOUSE; NERVE CELL DIFFERENTIATION; NEUROFIBROMATOSIS; NONHUMAN; ONCOGENE RAS; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0033674787     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410000290     Document Type: Article

References (61)

1. DNA lesions, inducible DNA repair, and cell division: Three key factors in mutagenesis and carcinogenesis
2. Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues
3. Epinephrine synthesis in the PC12 pheochromocytoma cell line
4. REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
5. Mouse models of tumor development in neurofibromatosis type 1
6. TrkA cross-linking mimics neuronal responses to nerve growth factor
7. Electron microscopic observations on the structure of the rat adrenal medulla. 1. The ultrastructure and organization of chromaffin cells in the normal adrenal medulla
8. The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes
9. Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis
10. Ultrastructure of nuclear 'inclusions' in pheochromocytoma and paraganglioma
11. Adrenergic differentiation potential in PC12 cells: Influence of sodium butyrate and dexamethasone
12. Determinants of phenylethanolamine-N-methyltransferase expression
13. Upstream sequences determine cell-specific transcription of the PNMT gene
14. Glucocorticoids stimulate transcription of the rat phenylethanolamine N-methyltransferase (PNMT) gene in vivo and in vitro
15. Neural-specific expression of the PNMT gene
16. Neurofibromatosis type 1 peripheral nerve tumors: Aberrant activation of the Ras pathway
17. Loss of cell-cell contact is induced by integrin-mediated cell-substratum adhesion in highly-motile and highly-metastatic hepatocellular carcinoma cells
18. Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication
19. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
20. Loss of neurofibromin in adrenal gland tumors from patients with neurofibromatosis type I
21. Tumour predisposition in mice heterozygous for a targeted mutation in Nf1
22. Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function
23. Parallel up-regulation of catecholamine biosynthetic enzymes by dexamethasone in PC12 cells
24. A small scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing
25. Neural regulation of phenylethanolamine N-methyltransferase (PNMT) gene expression in bovine chromaffin cells differs from other catecholamine enzyme genes
26. Microgravity decreases tyrosine hydroxylase expression in rat adrenals
27. Nerve growth factor is a mitogen for cultured chromaffin cells
28. Organization and complete nucleotide sequence of the gene encoding mouse phenylethanolamine N-methyltransferase
29. Neurofibromatosis type 1 (NF1): A protein truncation assay yielding identification of mutations in 73% of patients
30. Alternative splicing of exons 29 and 30 in the neurofibromatosis type 1 gene
31. Nerve growth factor receptor signaling in proliferation of normal adult rat chromaffin cells
32. Activated Raf-1 causes growth arrest in human small cell lung cancer cells
33. Von Recklinghausen neurofibromatosis
34. Neurotransmitter-synthesizing enzymes in 14 human neuroblastoma cell lines
35. The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes
36. Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype
37. NF1: A prevalent cause of tumorigenesis in human cancers?
38. Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice
39. Characterization of synaptic vesicles and related neuronal features in nerve growth factor and ras oncogene differentiated PC12 cells
40. Changes in structure and function of the adrenal medulla
41. Morphologic and cytochemical properties of a clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
42. Long-term effects of dexamethasone and nerve growth factor on adrenal medullary cells cultured from young adult rats
43. Chromaffin cell proliferation in the adult rat adrenal medulla
44. Catecholamine-synthesizing enzymes and chromogranin proteins in drug-induced proliferative lesions of the rat adrenal medulla
45. Immunocytochemical analysis of chromaffin cell proliferation in vitro
46. Polyoma-induced neoplasms of the mouse adrenal medulla. Characterization of the tumors and establishment of cell lines
47. Characterization of pheochromocytomas in a mouse strain with a targeted disruptive mutation of the neurofibromatosis gene Nf1
48. Sustained stimulation of rat adrenal chromaffin cell proliferation by reserpine
49. Immunohistochemical and morphological characterization of spontaneously occurring pheochromocytomas in the aging mouse
50. Comparative studies of chromaffin cell proliferation in the adrenal medulla of rats and mice
51. Vitamin D3-induced proliferative lesions in the rat adrenal medulla
52. KAT45, a noradrenergic human pheochromocytoma cell line producing corticotropin-releasing hormone
53. Mouse tumor model for neurofibromatosis type 1
54. Hyperactive Ras as a therapeutic target in neurofibromatosis type 1
55. Glucocorticoid regulation of phenylethanolamine N-methyltransferase in vivo
56. Adrenergic expression in the rat adrenal gland: Multiple developmental regulatory mechanisms
57. Phenylethanolamine N-methyltransferase gene expression: Synergistic activation by Egr-1, AP-2 and the glucocorticoid receptor
58. The neurofibromatosis type 1 gene encodes a protein related to GAP
59. Loss of NF1 alleles in phaeochromocytomas from patients with type I neurofibromatosis