De novo creation of MG1655-derived E. coli strains specifically designed for plasmid DNA production

Applied Microbiology and Biotechnology

Volumn 97, Issue 2, 2013, Pages 611-620

  Gonçalves, Geisa A L ^a,b   Prazeres, Duarte M F ^a,b   Monteiro, Gabriel A ^a,b   Prather, Kristala L J ^a,c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^c Massachusetts Institute of Technology   (United States)

Author keywords

DNA vaccine; Escherichia coli; Metabolic engineering; Plasmid biopharmaceuticals; Strain engineering

Indexed keywords

CARBON FLUXES; CENTRAL METABOLISMS; DNA VACCINE; DRY CELLS; E. COLI; EFFECT OF STRAIN; GENETIC BACKGROUNDS; NUCLEOTIDE SYNTHESIS; PARENTAL STRAINS; PENTOSE PHOSPHATE PATHWAY; PLASMID BIOPHARMACEUTICALS; PLASMID DNA; PLASMID DNA (PDNA); PRODUCTION STRAIN; STRAIN ENGINEERING; WILD TYPES; WILD-TYPE STRAIN;

BIOMOLECULES; DNA; GENES; GLUCOSE; METABOLIC ENGINEERING; VACCINES;

ESCHERICHIA COLI;

BACTERIAL PROTEIN; CARBON; PENTOSE; PLASMID DNA; PYKA PROTEIN; PYKF PROTEIN; UNCLASSIFIED DRUG;

BIOENGINEERING; COLIFORM BACTERIUM; ENZYME ACTIVITY; GLUCOSE; METABOLISM; MITOCHONDRIAL DNA; PLASMID; VACCINE;

ARTICLE; BACTERIAL CELL; BACTERIAL GENETICS; BACTERIAL STRAIN; DRUG EFFICACY; DRUG SYNTHESIS; ESCHERICHIA COLI; GENE INACTIVATION; NONHUMAN; NUCLEOTIDE METABOLISM;

ESCHERICHIA COLI; METABOLIC ENGINEERING; PLASMIDS; VACCINES, DNA;

ESCHERICHIA COLI;

EID: 84873993482     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4308-5     Document Type: Article

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