The impact of polyadenylation signals on plasmid nuclease-resistance and transgene expression

Journal of Gene Medicine

Volumn 9, Issue 5, 2007, Pages 392-402

  Azzoni, Adriano R ^a   Ribeiro, Sofia C ^a   Monteiro, Gabriel A ^a   Prazeres, Duarte M F ^a  

^a INSTITUTO SUPERIOR TÉCNICO   (Portugal)

Author keywords

DNA vaccines; Gene therapy; MRNA maturation; Nuclease resistance; Plasmid DNA vectors; Polyadenylation signal; Reporter protein expression

Indexed keywords

DNA VACCINE; GREEN FLUORESCENT PROTEIN; GROWTH HORMONE; MESSENGER RNA; NUCLEASE; PLASMID DNA; PLASMID VECTOR; POLYADENYLIC ACID;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DNA IMMUNIZATION; DNA STRUCTURE; FLOW CYTOMETRY; GENE EXPRESSION; HALF LIFE TIME; HELA CELL; HUMAN; HUMAN CELL; HYBRIDOMA; IN VITRO STUDY; INCUBATION TIME; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; POLYADENYLATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA STABILITY; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; STEADY STATE; TRANSGENE;

ANIMALS; CATTLE; CELL LINE; ENDONUCLEASES; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; PLASMIDS; POLY A; POLYADENYLATION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSGENES;

BOVINAE; MAMMALIA;

EID: 34249081884     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1031     Document Type: Article

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