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Volumn 82, Issue 5, 2009, Pages 805-813

Engineering of bacterial strains and vectors for the production of plasmid DNA

Author keywords

DNA vaccines; Escherichia coli; Gene therapy; Plasmid DNA; Strain engineering

Indexed keywords

BACTERIAL STRAINS; BIOPHARMACEUTICALS; CLINICAL TRIALS; DNA VACCINES; GENE THERAPY; HOST STRAINS; MANUFACTURING PROCESS; NON-TRADITIONAL; NON-VIRAL GENE THERAPIES; PLASMID DNA; PLASMID DNA (PDNA); PLASMID STABILITIES; PRODUCT SAFETIES; STRAIN ENGINEERING;

EID: 62949222607     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-1889-8     Document Type: Short Survey
Times cited : (46)

References (56)
  • 1
    • 0029877516 scopus 로고    scopus 로고
    • A replicational model for DNA recombination between direct repeats
    • X Bi LF Liu 1996 A replicational model for DNA recombination between direct repeats J Mol Biol 256 849 858
    • (1996) J Mol Biol , vol.256 , pp. 849-858
    • Bi, X.1    Liu, L.F.2
  • 2
    • 0033182630 scopus 로고    scopus 로고
    • Insertion of natural intron 6a-6b into a human cDNA-derived gene therapy vector for cystic fibrosis improves plasmid stability and permits facile RNA/DNA discrimination
    • AC Boyd F Popp U Michaelis H Davidson H Davidson-Smith A Doherty G McLachlan DJ Porteous S Seeber 1999 Insertion of natural intron 6a-6b into a human cDNA-derived gene therapy vector for cystic fibrosis improves plasmid stability and permits facile RNA/DNA discrimination J Gene Med 1 312 321
    • (1999) J Gene Med , vol.1 , pp. 312-321
    • Boyd, A.C.1    Popp, F.2    Michaelis, U.3    Davidson, H.4    Davidson-Smith, H.5    Doherty, A.6    McLachlan, G.7    Porteous, D.J.8    Seeber, S.9
  • 4
    • 33750621478 scopus 로고    scopus 로고
    • Inducible Escherichia coli fermentation for increased plasmid DNA production
    • AE Carnes CP Hodgson JA Williams 2006 Inducible Escherichia coli fermentation for increased plasmid DNA production Biotechnol Appl Biochem 45 155 166
    • (2006) Biotechnol Appl Biochem , vol.45 , pp. 155-166
    • Carnes, A.E.1    Hodgson, C.P.2    Williams, J.A.3
  • 5
    • 0031180535 scopus 로고    scopus 로고
    • The seventh copy of IS1 in Escherichia coli W3110 belongs to the IS1 A (IS1E) type which is the only IS1 type that transposes from chromosome to plasmids
    • JH Chen HT Yeh 1997 The seventh copy of IS1 in Escherichia coli W3110 belongs to the IS1 A (IS1E) type which is the only IS1 type that transposes from chromosome to plasmids Proc Natl Sci Counc Repub China B 21 100 105
    • (1997) Proc Natl Sci Counc Repub China B , vol.21 , pp. 100-105
    • Chen, J.H.1    Yeh, H.T.2
  • 6
    • 13844292517 scopus 로고    scopus 로고
    • Improved production and purification of minicircle DNA vector free of plasmid bacterial sequences and capable of persistent transgene expression in vivo
    • ZY Chen CY He MA Kay 2005 Improved production and purification of minicircle DNA vector free of plasmid bacterial sequences and capable of persistent transgene expression in vivo Hum Gene Ther 16 126 131
    • (2005) Hum Gene Ther , vol.16 , pp. 126-131
    • Chen, Z.Y.1    He, C.Y.2    Kay, M.A.3
  • 8
    • 0035936936 scopus 로고    scopus 로고
    • Purification of essentially RNA free plasmid DNA using a modified Escherichia coli host strain expressing ribonuclease A
    • GD Cooke RM Cranenburgh JAJ Hanak P Dunnill DR Thatcher JM Ward 2001 Purification of essentially RNA free plasmid DNA using a modified Escherichia coli host strain expressing ribonuclease A J Biotechnol 85 297 304
    • (2001) J Biotechnol , vol.85 , pp. 297-304
    • Cooke, G.D.1    Cranenburgh, R.M.2    Hanak, J.A.J.3    Dunnill, P.4    Thatcher, D.R.5    Ward, J.M.6
  • 9
    • 0035286339 scopus 로고    scopus 로고
    • Escherichia coli strains that allow antibiotic-free plasmid selection and maintenance by repressor titration
    • RM Cranenburgh JA Hanak SG Williams DJ Sherratt 2001 Escherichia coli strains that allow antibiotic-free plasmid selection and maintenance by repressor titration Nucleic Acids Res 29 E26
    • (2001) Nucleic Acids Res , vol.29 , pp. 26
    • Cranenburgh, R.M.1    Hanak, J.A.2    Williams, S.G.3    Sherratt, D.J.4
  • 10
    • 4644278635 scopus 로고    scopus 로고
    • Effect of plasmid copy number and lac operator sequence on antibiotic-free plasmid selection by operator-repressor titration in Escherichia coli
    • RM Cranenburgh KS Lewis JA Hanak 2004 Effect of plasmid copy number and lac operator sequence on antibiotic-free plasmid selection by operator-repressor titration in Escherichia coli J Mol Microbiol Biotechnol 7 197 203
    • (2004) J Mol Microbiol Biotechnol , vol.7 , pp. 197-203
    • Cranenburgh, R.M.1    Lewis, K.S.2    Hanak, J.A.3
  • 11
    • 38149049119 scopus 로고    scopus 로고
    • Growth medium selection and its economic impact on plasmid DNA production
    • MK Danquah GM Forde 2007 Growth medium selection and its economic impact on plasmid DNA production J Biosci Bioeng 104 490 497
    • (2007) J Biosci Bioeng , vol.104 , pp. 490-497
    • Danquah, M.K.1    Forde, G.M.2
  • 12
    • 0031436820 scopus 로고    scopus 로고
    • A new DNA vehicle for nonviral gene delivery: Supercoiled minicircle
    • AM Darquet B Cameron P Wils D Scherman J Crouzet 1997 A new DNA vehicle for nonviral gene delivery: supercoiled minicircle Gene Ther 4 1341 1349
    • (1997) Gene Ther , vol.4 , pp. 1341-1349
    • Darquet, A.M.1    Cameron, B.2    Wils, P.3    Scherman, D.4    Crouzet, J.5
  • 13
    • 0242695018 scopus 로고    scopus 로고
    • Antibiotic-free bacterial strain selection using antisense peptide nucleic acid
    • R Dryselius N Nekhotiaeva PE Nielsen L Good 2003 Antibiotic-free bacterial strain selection using antisense peptide nucleic acid BioTechniques 35 1060 1064
    • (2003) BioTechniques , vol.35 , pp. 1060-1064
    • Dryselius, R.1    Nekhotiaeva, N.2    Nielsen, P.E.3    Good, L.4
  • 16
    • 50849136499 scopus 로고    scopus 로고
    • Plasmid selection in Escherichia coli using an endogenous essential gene marker
    • S Goh L Good 2008 Plasmid selection in Escherichia coli using an endogenous essential gene marker BMC Biotechnol 8 61
    • (2008) BMC Biotechnol , vol.8 , pp. 61
    • Goh, S.1    Good, L.2
  • 18
    • 2942511439 scopus 로고    scopus 로고
    • A host/plasmid system that is not dependent on antibiotics and antibiotic resistance genes for stable plasmid maintenance in Escherichia coli
    • P Hägg JW de Pohl F Abdulkarim LA Isaksson 2004 A host/plasmid system that is not dependent on antibiotics and antibiotic resistance genes for stable plasmid maintenance in Escherichia coli J Biotechnol 111 17 30
    • (2004) J Biotechnol , vol.111 , pp. 17-30
    • Hägg, P.1    De Pohl, J.W.2    Abdulkarim, F.3    Isaksson, L.A.4
  • 19
    • 0033826855 scopus 로고    scopus 로고
    • Design and construction of an experimental HIV-1 vaccine for a year-2000 clinical trial in Kenya
    • T Hanke AJ McMichael 2000 Design and construction of an experimental HIV-1 vaccine for a year-2000 clinical trial in Kenya Nat Med 6 951 955
    • (2000) Nat Med , vol.6 , pp. 951-955
    • Hanke, T.1    McMichael, A.J.2
  • 21
    • 0028978028 scopus 로고
    • Cancer gene therapy using plasmid DNA: Purification of DNA for human clinical trials
    • NA Horn JA Meek G Budahazi M Marquet 1995 Cancer gene therapy using plasmid DNA: purification of DNA for human clinical trials Hum Gene Ther 6 565 573
    • (1995) Hum Gene Ther , vol.6 , pp. 565-573
    • Horn, N.A.1    Meek, J.A.2    Budahazi, G.3    Marquet, M.4
  • 22
    • 52449104809 scopus 로고    scopus 로고
    • DNA vaccines: Ready for prime time?
    • MA Kutzler DB. Weiner 2008 DNA vaccines: ready for prime time? Nat Rev Genet 9 776 788
    • (2008) Nat Rev Genet , vol.9 , pp. 776-788
    • Kutzler, M.A.1    Weiner, D.B.2
  • 23
    • 46349094993 scopus 로고    scopus 로고
    • Rational vector design for efficient non-viral gene delivery: Challenges facing the use of plasmid DNA
    • J Mairhofer R Grabherr 2008 Rational vector design for efficient non-viral gene delivery: challenges facing the use of plasmid DNA Mol Biotechnol 39 97 104
    • (2008) Mol Biotechnol , vol.39 , pp. 97-104
    • Mairhofer, J.1    Grabherr, R.2
  • 24
    • 38849198564 scopus 로고    scopus 로고
    • A novel antibiotic free plasmid selection system: Advances in safe and efficient DNA therapy
    • J Mairhofer I Pfaffenzeller D Merz R Grabherr 2008 A novel antibiotic free plasmid selection system: advances in safe and efficient DNA therapy Biotechnol J 3 83 89
    • (2008) Biotechnol J , vol.3 , pp. 83-89
    • Mairhofer, J.1    Pfaffenzeller, I.2    Merz, D.3    Grabherr, R.4
  • 25
    • 58149193835 scopus 로고    scopus 로고
    • Minicircle-DNA production by site specific recombination and protein-DNA interaction chromatography
    • P Mayrhofer M Blaesen M Schleef W Jechlinger 2008 Minicircle-DNA production by site specific recombination and protein-DNA interaction chromatography J Gene Med 10 1253 1269
    • (2008) J Gene Med , vol.10 , pp. 1253-1269
    • Mayrhofer, P.1    Blaesen, M.2    Schleef, M.3    Jechlinger, W.4
  • 27
    • 62949224376 scopus 로고    scopus 로고
    • Chapter 5: Outer membrane
    • Neidhardt F et al (eds) ASM Press, Washington D.C. Available via EcoSal
    • nd edn. ASM Press, Washington D.C. Available via EcoSal. http://www.ecosal.org/ ecosal/chapters/index.jsp?005. Accessed 20 Jan 2009
    • (1996) nd Edn.
    • Nikaido, H.1
  • 29
    • 0033990746 scopus 로고    scopus 로고
    • Effects of growth medium selection on plasmid DNA production and initial processing steps
    • RD O'Kennedy C Baldwin E Keshavarz-Moore 2000 Effects of growth medium selection on plasmid DNA production and initial processing steps J Biotechnol 76 175 183
    • (2000) J Biotechnol , vol.76 , pp. 175-183
    • O'Kennedy, R.D.1    Baldwin, C.2    Keshavarz-Moore, E.3
  • 30
    • 23344449885 scopus 로고    scopus 로고
    • Development of a robust, versatile, and scalable inoculum train for the production of a DNA vaccine
    • J Okonkowski L Kizer-Bentley K Listner D Robinson M Chartrain 2005 Development of a robust, versatile, and scalable inoculum train for the production of a DNA vaccine Biotechnol Prog 21 1038 1047
    • (2005) Biotechnol Prog , vol.21 , pp. 1038-1047
    • Okonkowski, J.1    Kizer-Bentley, L.2    Listner, K.3    Robinson, D.4    Chartrain, M.5
  • 31
    • 49949118846 scopus 로고    scopus 로고
    • Recombination frequency in plasmid DNA containing direct repeats-predictive correlation with repeat and intervening sequence length
    • PH Oliveira F Lemos GA Monteiro DM Prazeres 2008 Recombination frequency in plasmid DNA containing direct repeats-predictive correlation with repeat and intervening sequence length Plasmid 60 159 165
    • (2008) Plasmid , vol.60 , pp. 159-165
    • Oliveira, P.H.1    Lemos, F.2    Monteiro, G.A.3    Prazeres, D.M.4
  • 32
    • 33646822101 scopus 로고    scopus 로고
    • Global transcriptional analysis of metabolic burden due to plasmid maintenance in Escherichia coli DH5α during batch fermentation
    • DS Ow PM Nissom R Philp SK Oh MG Yap 2006 Global transcriptional analysis of metabolic burden due to plasmid maintenance in Escherichia coli DH5α during batch fermentation Enzyme Microb Technol 39 391 398
    • (2006) Enzyme Microb Technol , vol.39 , pp. 391-398
    • Ow, D.S.1    Nissom, P.M.2    Philp, R.3    Oh, S.K.4    Yap, M.G.5
  • 33
    • 34548426597 scopus 로고    scopus 로고
    • Inactivating FruR global regulator in plasmid-bearing Escherichia coli alters metabolic gene expression and improves growth rate
    • DS Ow RM Lee PM Nissom R Philp SK Oh MG Yap 2007 Inactivating FruR global regulator in plasmid-bearing Escherichia coli alters metabolic gene expression and improves growth rate J Biotechnol 131 261 269
    • (2007) J Biotechnol , vol.131 , pp. 261-269
    • Ow, D.S.1    Lee, R.M.2    Nissom, P.M.3    Philp, R.4    Oh, S.K.5    Yap, M.G.6
  • 34
    • 62949159921 scopus 로고    scopus 로고
    • Enhancement of plasmid DNA yields during fed-batch culture with a fruR-knockout Escherichia coli strain
    • DS Ow MG Yap SK Oh 2009 Enhancement of plasmid DNA yields during fed-batch culture with a fruR-knockout Escherichia coli strain Biotechnol Appl Biochem 52 53 59
    • (2009) Biotechnol Appl Biochem , vol.52 , pp. 53-59
    • Ow, D.S.1    Yap, M.G.2    Oh, S.K.3
  • 35
    • 49149086922 scopus 로고    scopus 로고
    • Use of Vaxfectin adjuvant with DNA vaccine encoding the measles virus hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques against measles virus
    • CH Pan GS Jimenez N Nair Q Wei RJ Adams FP Polack A Rolland A Vilalta DE Griffin 2008 Use of Vaxfectin adjuvant with DNA vaccine encoding the measles virus hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques against measles virus Clin Vaccine Immunol 15 1214 1221
    • (2008) Clin Vaccine Immunol , vol.15 , pp. 1214-1221
    • Pan, C.H.1    Jimenez, G.S.2    Nair, N.3    Wei, Q.4    Adams, R.J.5    Polack, F.P.6    Rolland, A.7    Vilalta, A.8    Griffin, D.E.9
  • 36
    • 19944421092 scopus 로고    scopus 로고
    • Glucose metabolism at high density growth of E. coli B and E. coli K: Differences in metabolic pathways are responsible for efficient glucose utilization in E. coli B as determined by microarrays and Northern blot analyses
    • JN Phue SB Noronha R Hattacharyya AJ Wolfe J Shiloach 2005 Glucose metabolism at high density growth of E. coli B and E. coli K: differences in metabolic pathways are responsible for efficient glucose utilization in E. coli B as determined by microarrays and Northern blot analyses Biotechnol Bioeng 90 805 820
    • (2005) Biotechnol Bioeng , vol.90 , pp. 805-820
    • Phue, J.N.1    Noronha, S.B.2    Hattacharyya, R.3    Wolfe, A.J.4    Shiloach, J.5
  • 37
    • 55549128624 scopus 로고    scopus 로고
    • Modified Escherichia coli B (BL21), a superior producer of plasmid DNA compared with Escherichia coli K (DH5alpha)
    • JN Phue SJ Lee L Trinh J Shiloach 2008 Modified Escherichia coli B (BL21), a superior producer of plasmid DNA compared with Escherichia coli K (DH5alpha) Biotechnol Bioeng 101 831 836
    • (2008) Biotechnol Bioeng , vol.101 , pp. 831-836
    • Phue, J.N.1    Lee, S.J.2    Trinh, L.3    Shiloach, J.4
  • 38
    • 0036900521 scopus 로고    scopus 로고
    • Dynamic cellular location of bacterial plasmids
    • J Pogliano 2002 Dynamic cellular location of bacterial plasmids Curr Opin Microbiol 5 586 590
    • (2002) Curr Opin Microbiol , vol.5 , pp. 586-590
    • Pogliano, J.1
  • 40
    • 33751510492 scopus 로고    scopus 로고
    • Identification and characterization of IS1 transposition in plasmid amplification mutants of E. coli clones producing DNA vaccines
    • KL Prather MC Edmonds JW Herod 2006 Identification and characterization of IS1 transposition in plasmid amplification mutants of E. coli clones producing DNA vaccines Appl Microbiol Biotechnol 73 815 826
    • (2006) Appl Microbiol Biotechnol , vol.73 , pp. 815-826
    • Prather, K.L.1    Edmonds, M.C.2    Herod, J.W.3
  • 41
    • 0347899375 scopus 로고    scopus 로고
    • Design of flowsheets for the recovery and purification of plasmids for gene therapy and DNA vaccination
    • DMF Prazeres GNM Ferreira 2004 Design of flowsheets for the recovery and purification of plasmids for gene therapy and DNA vaccination Chem Eng Process 43 609 624
    • (2004) Chem Eng Process , vol.43 , pp. 609-624
    • Prazeres, D.M.F.1    Ferreira, G.N.M.2
  • 44
    • 19044384376 scopus 로고    scopus 로고
    • Genomic comparisons among Escherichia coli strains B, K-12, and O157:H7 using IS elements as molecular markers
    • D Schneider E Duperchy J Depeyrot E Coursange R Lenski M Blot 2002 Genomic comparisons among Escherichia coli strains B, K-12, and O157:H7 using IS elements as molecular markers BMC Microbiol 2 18
    • (2002) BMC Microbiol , vol.2 , pp. 18
    • Schneider, D.1    Duperchy, E.2    Depeyrot, J.3    Coursange, E.4    Lenski, R.5    Blot, M.6
  • 46
    • 15244339715 scopus 로고    scopus 로고
    • Improvement of pCOR plasmid copy number for pharmaceutical applications
    • F Soubrier B Laborderie B Cameron 2005 Improvement of pCOR plasmid copy number for pharmaceutical applications Appl Microbiol Biotechnol 66 683 688
    • (2005) Appl Microbiol Biotechnol , vol.66 , pp. 683-688
    • Soubrier, F.1    Laborderie, B.2    Cameron, B.3
  • 47
    • 0031659852 scopus 로고    scopus 로고
    • Timing, self-control and a sense of direction are the secrets of multicopy plasmid stability
    • D Summers 1998 Timing, self-control and a sense of direction are the secrets of multicopy plasmid stability Mol Microbiol 29 1137 1145
    • (1998) Mol Microbiol , vol.29 , pp. 1137-1145
    • Summers, D.1
  • 48
    • 18444380606 scopus 로고    scopus 로고
    • Separate-component-stabilization system for protein and DNA production without the use of antibiotics
    • CY Szpirer MC Milinkovitch 2005 Separate-component-stabilization system for protein and DNA production without the use of antibiotics BioTechniques 38 775 781
    • (2005) BioTechniques , vol.38 , pp. 775-781
    • Szpirer, C.Y.1    Milinkovitch, M.C.2
  • 49
    • 33645462420 scopus 로고    scopus 로고
    • RecET driven chromosomal gene targeting to generate a RecA deficient Escherichia coli strain for Cre mediated production of minicircle DNA
    • O Tolmachov I Palaszewski B Bigger C Coutelle 2006 RecET driven chromosomal gene targeting to generate a RecA deficient Escherichia coli strain for Cre mediated production of minicircle DNA BMC Biotechnol 6 17
    • (2006) BMC Biotechnol , vol.6 , pp. 17
    • Tolmachov, O.1    Palaszewski, I.2    Bigger, B.3    Coutelle, C.4
  • 50
    • 25144499113 scopus 로고    scopus 로고
    • Transposition is modulated by a diverse set of host factors in Escherichia coli and is stimulated by nutritional stress
    • E Twiss AM Coros NP Tavakoli KM Derbyshire 2005 Transposition is modulated by a diverse set of host factors in Escherichia coli and is stimulated by nutritional stress Mol Microbiol 57 1593 1607
    • (2005) Mol Microbiol , vol.57 , pp. 1593-1607
    • Twiss, E.1    Coros, A.M.2    Tavakoli, N.P.3    Derbyshire, K.M.4
  • 52
    • 39749143172 scopus 로고    scopus 로고
    • Development of an antibiotic-free plasmid selection system based on glycine auxotrophy for recombinant protein overproduction in Escherichia coli
    • L Vidal J Pinsach G Striedner G Caminal P Ferrer 2008 Development of an antibiotic-free plasmid selection system based on glycine auxotrophy for recombinant protein overproduction in Escherichia coli J Biotechnol 134 127 136
    • (2008) J Biotechnol , vol.134 , pp. 127-136
    • Vidal, L.1    Pinsach, J.2    Striedner, G.3    Caminal, G.4    Ferrer, P.5
  • 53
    • 0034986241 scopus 로고    scopus 로고
    • Medium design for plasmid DNA production based on stoichiometric model
    • Z Wang G Le Y Shi G Wegrzyn 2001 Medium design for plasmid DNA production based on stoichiometric model Process Biochem 36 1085 1093
    • (2001) Process Biochem , vol.36 , pp. 1085-1093
    • Wang, Z.1    Le, G.2    Shi, Y.3    Wegrzyn, G.4
  • 54
    • 53549102227 scopus 로고    scopus 로고
    • Host strain influences on supercoiled plasmid DNA production in Escherichia coli: Implications for efficient design of large-scale processes
    • SY Yau E Keshavarz-Moore J Ward 2008 Host strain influences on supercoiled plasmid DNA production in Escherichia coli: Implications for efficient design of large-scale processes Biotechnol Bioeng 101 529 544
    • (2008) Biotechnol Bioeng , vol.101 , pp. 529-544
    • Yau, S.Y.1    Keshavarz-Moore, E.2    Ward, J.3
  • 55
    • 34548297787 scopus 로고    scopus 로고
    • Identification of Escherichia coli host cell for high plasmid stability and improved production of antihuman ovarian carcinoma x antihuman CD3 single-chain bispecific antibody
    • JB Zhao DZ Wei WY Tong 2007 Identification of Escherichia coli host cell for high plasmid stability and improved production of antihuman ovarian carcinoma x antihuman CD3 single-chain bispecific antibody Appl Microbiol Biotechnol 76 795 800
    • (2007) Appl Microbiol Biotechnol , vol.76 , pp. 795-800
    • Zhao, J.B.1    Wei, D.Z.2    Tong, W.Y.3
  • 56
    • 0035753462 scopus 로고    scopus 로고
    • Mechanisms of plasmid stable maintenance with special focus on plasmid addiction systems
    • U Zielenkiewicz P Ceglowski 2001 Mechanisms of plasmid stable maintenance with special focus on plasmid addiction systems Acta Biochim Pol 48 1003 1023
    • (2001) Acta Biochim Pol , vol.48 , pp. 1003-1023
    • Zielenkiewicz, U.1    Ceglowski, P.2


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