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Volumn 8, Issue 2, 2013, Pages

Accelerated Cell Aging in Female APOE-ε4 Carriers: Implications for Hormone Therapy Use

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4; ESTROGEN; PROGESTERONE;

EID: 84873911119     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054713     Document Type: Article
Times cited : (49)

References (65)
  • 1
    • 38849197893 scopus 로고    scopus 로고
    • Telomere attrition is associated with inflammation, low fetuin-A levels and high mortality in prevalent haemodialysis patients
    • Carrero JJ, Stenvinkel P, Fellstrom B, Qureshi AR, Lamb K, et al. (2008) Telomere attrition is associated with inflammation, low fetuin-A levels and high mortality in prevalent haemodialysis patients. J Int Med 263: 302-312.
    • (2008) J Int Med , vol.263 , pp. 302-312
    • Carrero, J.J.1    Stenvinkel, P.2    Fellstrom, B.3    Qureshi, A.R.4    Lamb, K.5
  • 2
    • 79955942152 scopus 로고    scopus 로고
    • Cumulative inflammatory load is associated with short leukocyte telomere length in the health, aging and body composition study
    • O'Donovan A, Pantell MS, Puterman E, Dhabhar FS, Blackburn E, et al. (2011) Cumulative inflammatory load is associated with short leukocyte telomere length in the health, aging and body composition study. Plos One 6: e19687.
    • (2011) Plos One , vol.6
    • O'Donovan, A.1    Pantell, M.S.2    Puterman, E.3    Dhabhar, F.S.4    Blackburn, E.5
  • 3
    • 84873916797 scopus 로고    scopus 로고
    • Leukocyte telomere dynamics, human aging, and life span
    • In: Masoro EJ, Austad SN, editors, Academic Press, London
    • Aviv A (2011) Leukocyte telomere dynamics, human aging, and life span. In: Masoro EJ, Austad SN, editors. Handbook of the Biology of Aging. Academic Press, London. 163-176.
    • (2011) Handbook of the Biology of Aging , pp. 163-176
    • Aviv, A.1
  • 4
    • 0025731583 scopus 로고
    • Structure and function of telomeres
    • Blackburn EH, (1991) Structure and function of telomeres. Nature 350: 569-573.
    • (1991) Nature , vol.350 , pp. 569-573
    • Blackburn, E.H.1
  • 5
    • 0034597794 scopus 로고    scopus 로고
    • Telomere states and cell fates
    • Blackburn EH, (2000) Telomere states and cell fates. Nature 408: 53-56.
    • (2000) Nature , vol.408 , pp. 53-56
    • Blackburn, E.H.1
  • 7
    • 10744225878 scopus 로고    scopus 로고
    • Short telomeres are associated with increased carotid atherosclerosis in hypertensive subjects
    • Benetos A, Gardner JP, Zureik M, Labat C, Xiaobin L, et al. (2004) Short telomeres are associated with increased carotid atherosclerosis in hypertensive subjects. Hypertension 43: 182-185.
    • (2004) Hypertension , vol.43 , pp. 182-185
    • Benetos, A.1    Gardner, J.P.2    Zureik, M.3    Labat, C.4    Xiaobin, L.5
  • 8
    • 0033747604 scopus 로고    scopus 로고
    • Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor?
    • von Zglinicki T, Serra V, Lorenz M, Saretzki G, Lenxen-Grobimlighaus R, et al. (2000) Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor? Lab Invest 80: 1739-1747.
    • (2000) Lab Invest , vol.80 , pp. 1739-1747
    • von Zglinicki, T.1    Serra, V.2    Lorenz, M.3    Saretzki, G.4    Lenxen-Grobimlighaus, R.5
  • 10
    • 79955563342 scopus 로고    scopus 로고
    • Telomeres, telomerase, stress and aging
    • In: Berntson GG, Cacioppo JT, editors, New Jersey: John Wiley and Sons
    • Lin J, Epel ES, Blackburn EH (2009) Telomeres, telomerase, stress and aging. In: Berntson GG, Cacioppo JT, editors. Handbook of Neuroscience for the Behavioral Sciences. New Jersey: John Wiley and Sons. 1280-1295.
    • (2009) Handbook of Neuroscience for the Behavioral Sciences , pp. 1280-1295
    • Lin, J.1    Epel, E.S.2    Blackburn, E.H.3
  • 11
    • 0037308404 scopus 로고    scopus 로고
    • Association between telomere length in blood and mortality in people aged 60 years or older
    • Cawthon RM, Smith KR, O'Brien E, Sivatchenko A, Kerber RA, (2003) Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 361: 393-395.
    • (2003) Lancet , vol.361 , pp. 393-395
    • Cawthon, R.M.1    Smith, K.R.2    O'Brien, E.3    Sivatchenko, A.4    Kerber, R.A.5
  • 12
    • 33746812586 scopus 로고    scopus 로고
    • Shorter telomeres are associated with mortality in those with APOE ε4 and dementia
    • Honig LS, Schupf N, Lee JH, Tang MX, Mayeux R, (2006) Shorter telomeres are associated with mortality in those with APOE ε4 and dementia. Ann Neurol 60: 181-187.
    • (2006) Ann Neurol , vol.60 , pp. 181-187
    • Honig, L.S.1    Schupf, N.2    Lee, J.H.3    Tang, M.X.4    Mayeux, R.5
  • 13
    • 33746828140 scopus 로고    scopus 로고
    • Telomere length predicts poststroke mortality, dementia, and cognitive decline
    • Martin-Ruiz CM, Dickinson HO, Keys B, Rowan E, Kenny RA, et al. (2006) Telomere length predicts poststroke mortality, dementia, and cognitive decline. Ann. Neurol. 60: 174-180.
    • (2006) Ann. Neurol , vol.60 , pp. 174-180
    • Martin-Ruiz, C.M.1    Dickinson, H.O.2    Keys, B.3    Rowan, E.4    Kenny, R.A.5
  • 14
    • 61849146097 scopus 로고    scopus 로고
    • The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men
    • Epel ES, Merkin SS, Cawthon R, Blackburn EH, Adler NE, et al. (2009) The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men. Aging 1: 81-88.
    • (2009) Aging , vol.1 , pp. 81-88
    • Epel, E.S.1    Merkin, S.S.2    Cawthon, R.3    Blackburn, E.H.4    Adler, N.E.5
  • 16
    • 80052617023 scopus 로고    scopus 로고
    • Telomere length and cognitive function in community-dwelling elders: Findings from the Health ABC Study
    • Yaffe K, Lindquist K, Kluse M, Cawthon R, Harris T, et al. (2009) Telomere length and cognitive function in community-dwelling elders: Findings from the Health ABC Study. Neurobio Aging 32: 2055-2060.
    • (2009) Neurobio Aging , vol.32 , pp. 2055-2060
    • Yaffe, K.1    Lindquist, K.2    Kluse, M.3    Cawthon, R.4    Harris, T.5
  • 17
    • 77951978549 scopus 로고    scopus 로고
    • Leukocyte telomere length is associated with cognitive performance in healthy women
    • Valdes AM, Deary IJ, Gardner J, Kimura M, Lu X, et al. (2010) Leukocyte telomere length is associated with cognitive performance in healthy women. Neurobiol. Aging 31: 986-992.
    • (2010) Neurobiol. Aging , vol.31 , pp. 986-992
    • Valdes, A.M.1    Deary, I.J.2    Gardner, J.3    Kimura, M.4    Lu, X.5
  • 18
    • 79952003582 scopus 로고    scopus 로고
    • Relative telomere length and cognitive decline in the Nurses' Health Study
    • Devore EE, Prescott J, De Vivo I, Grodstein F, (2011) Relative telomere length and cognitive decline in the Nurses' Health Study. Neurosci Lett 492: 15-18.
    • (2011) Neurosci Lett , vol.492 , pp. 15-18
    • Devore, E.E.1    Prescott, J.2    De Vivo, I.3    Grodstein, F.4
  • 19
    • 77956578925 scopus 로고    scopus 로고
    • Cognitive performance and leukocyte telomere length in two narrow age-range cohorts: a population study
    • Mather KA, Jorm AF, Anstey KJ, Milburn PJ, Easteal S, et al. (2010) Cognitive performance and leukocyte telomere length in two narrow age-range cohorts: a population study. BMC Geriatr. 10: 62.
    • (2010) BMC Geriatr , vol.10 , pp. 62
    • Mather, K.A.1    Jorm, A.F.2    Anstey, K.J.3    Milburn, P.J.4    Easteal, S.5
  • 20
    • 78650990326 scopus 로고    scopus 로고
    • Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
    • Jaskelioff M, Muller FL, Paik JH, Thomas E, Jiang S, et al. (2011) Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature 469: 102-106.
    • (2011) Nature , vol.469 , pp. 102-106
    • Jaskelioff, M.1    Muller, F.L.2    Paik, J.H.3    Thomas, E.4    Jiang, S.5
  • 22
    • 0028997817 scopus 로고
    • Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease
    • Roses AD, (1995) Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease. Ann. Neurol. 38: 6-14.
    • (1995) Ann. Neurol , vol.38 , pp. 6-14
    • Roses, A.D.1
  • 23
    • 0030870127 scopus 로고    scopus 로고
    • Apolipoprotein E phenotype and cognitive decline in a prospective study of elderly community women
    • Yaffe K, Cauley J, Sands L, Browner W, (1997) Apolipoprotein E phenotype and cognitive decline in a prospective study of elderly community women. Arch Neurol. 54: 1110-1114.
    • (1997) Arch Neurol , vol.54 , pp. 1110-1114
    • Yaffe, K.1    Cauley, J.2    Sands, L.3    Browner, W.4
  • 24
    • 58849118052 scopus 로고    scopus 로고
    • Mortality, dementia, and apolipoprotein E genotype in elderly white women in the United States
    • Little DM, Crooks VC, Petitti DB, Chiu V, Schellenberg GD, et al. (2009) Mortality, dementia, and apolipoprotein E genotype in elderly white women in the United States. J Am Geriatr Soc. 57: 231-6.
    • (2009) J Am Geriatr Soc , vol.57 , pp. 231-236
    • Little, D.M.1    Crooks, V.C.2    Petitti, D.B.3    Chiu, V.4    Schellenberg, G.D.5
  • 25
    • 84859080364 scopus 로고    scopus 로고
    • Association between ApoE phenotypes and telomere erosion in Alzheimer's disease
    • doi: 10.1093/gerona/glr185
    • Takata Y, Kikukawa M, Hanya H, Koyama S, Shimizu S, et al. (2011) Association between ApoE phenotypes and telomere erosion in Alzheimer's disease. J Gerontol A Biol Sci Med Sci doi: 10.1093/gerona/glr185.
    • (2011) J Gerontol A Biol Sci Med Sci
    • Takata, Y.1    Kikukawa, M.2    Hanya, H.3    Koyama, S.4    Shimizu, S.5
  • 28
    • 0034107095 scopus 로고    scopus 로고
    • Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells
    • Misiti S, Nanni S, Fontemaggi G, Cong YS, Wen J, et al. (2000) Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells. Mol. Cell. Biol. 20: 3764-3771.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 3764-3771
    • Misiti, S.1    Nanni, S.2    Fontemaggi, G.3    Cong, Y.S.4    Wen, J.5
  • 29
    • 35948935663 scopus 로고    scopus 로고
    • Potential roles for estrogen regulation of telomerase activity in aging
    • Bayne S, Jones ME, Li H, Liu J-P, (2007) Potential roles for estrogen regulation of telomerase activity in aging. Annals NY Acad Sci 1114: 48-55.
    • (2007) Annals NY Acad Sci , vol.1114 , pp. 48-55
    • Bayne, S.1    Jones, M.E.2    Li, H.3    Liu, J.-P.4
  • 30
    • 48049098413 scopus 로고    scopus 로고
    • Estrogen receptor-alpha and endothelial nitric oxide synthase nuclear complex regulates transcription of human telomerase
    • Grasselli A, Nanni S, Colussi C, Aiello A, Benvenuti V, et al. (2008) Estrogen receptor-alpha and endothelial nitric oxide synthase nuclear complex regulates transcription of human telomerase. Circ. Res. 103: 34-42.
    • (2008) Circ. Res , vol.103 , pp. 34-42
    • Grasselli, A.1    Nanni, S.2    Colussi, C.3    Aiello, A.4    Benvenuti, V.5
  • 31
    • 58049094139 scopus 로고    scopus 로고
    • Estrogen receptor-alpha mediates the effects of estradiol on telomerase activity in human mesenchymal stem cells
    • Cha Y, Kwon SJ, Seol W, Park KS, (2008) Estrogen receptor-alpha mediates the effects of estradiol on telomerase activity in human mesenchymal stem cells. Mol. Cells 26: 454-458.
    • (2008) Mol. Cells , vol.26 , pp. 454-458
    • Cha, Y.1    Kwon, S.J.2    Seol, W.3    Park, K.S.4
  • 32
    • 70349569075 scopus 로고    scopus 로고
    • Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells
    • Calado RT, Yewdell WT, Wilkerson KL, Regal JA, Kajigaya S, et al. (2009) Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells. Blood 114: 2236-2243.
    • (2009) Blood , vol.114 , pp. 2236-2243
    • Calado, R.T.1    Yewdell, W.T.2    Wilkerson, K.L.3    Regal, J.A.4    Kajigaya, S.5
  • 33
    • 52949136618 scopus 로고    scopus 로고
    • Raloxifene protects endothelial cell function against oxidative stress
    • Wong CM, Yung LM, Leung FP, Tsang SY, Au CL, et al. (2008) Raloxifene protects endothelial cell function against oxidative stress. Br. J. Pharmacol. 155: 326-334.
    • (2008) Br. J. Pharmacol , vol.155 , pp. 326-334
    • Wong, C.M.1    Yung, L.M.2    Leung, F.P.3    Tsang, S.Y.4    Au, C.L.5
  • 35
  • 37
    • 79952310846 scopus 로고    scopus 로고
    • Greater endogenous estrogen exposure is associated with longer telomeres in postmenopausal women at risk for cognitive decline
    • Lin J, Kroenke CH, Epel E, Kenna HA, Wolkowitz OM, et al. (2011) Greater endogenous estrogen exposure is associated with longer telomeres in postmenopausal women at risk for cognitive decline. Brain Research 1379: 224-231.
    • (2011) Brain Research , vol.1379 , pp. 224-231
    • Lin, J.1    Kroenke, C.H.2    Epel, E.3    Kenna, H.A.4    Wolkowitz, O.M.5
  • 38
    • 24644482376 scopus 로고    scopus 로고
    • Effect of long-term hormone therapy on telomere length in postmenopausal women
    • Lee DC, Im JA, Kim JH, Lee HR, Shim JY, (2005) Effect of long-term hormone therapy on telomere length in postmenopausal women. Yonsei Med. J. 46: 471-479.
    • (2005) Yonsei Med. J , vol.46 , pp. 471-479
    • Lee, D.C.1    Im, J.A.2    Kim, J.H.3    Lee, H.R.4    Shim, J.Y.5
  • 39
    • 38749147684 scopus 로고    scopus 로고
    • The association between physical activity in leisure time and leukocyte telomere length
    • Cherkas LF, Hunkin JL, Kato BS, Richards B, Gardner JP, et al. (2008) The association between physical activity in leisure time and leukocyte telomere length. Arch Intern Med. 168: 154-158.
    • (2008) Arch Intern Med , vol.168 , pp. 154-158
    • Cherkas, L.F.1    Hunkin, J.L.2    Kato, B.S.3    Richards, B.4    Gardner, J.P.5
  • 41
    • 0035686793 scopus 로고    scopus 로고
    • Estrogens, selective estrogen receptor modulators, and dementia: What is the evidence?
    • Yaffe K, (2006) Estrogens, selective estrogen receptor modulators, and dementia: What is the evidence? Annals NYAS 949: 215-222.
    • (2006) Annals NYAS , vol.949 , pp. 215-222
    • Yaffe, K.1
  • 42
    • 0031454921 scopus 로고    scopus 로고
    • Estrogen up-regulates apolipoprotein E(ApoE) gene expression by increasing ApoE mRNA in the translating pool via the estrogen receptor alpha-mediated pathway
    • Srivastava RA, Srivastava N, Averna M, Lin RC, Korach KS, et al. (1997) Estrogen up-regulates apolipoprotein E(ApoE) gene expression by increasing ApoE mRNA in the translating pool via the estrogen receptor alpha-mediated pathway. J. Biol. Chem. 272: 33360-33366.
    • (1997) J. Biol. Chem , vol.272 , pp. 33360-33366
    • Srivastava, R.A.1    Srivastava, N.2    Averna, M.3    Lin, R.C.4    Korach, K.S.5
  • 43
    • 0032080001 scopus 로고    scopus 로고
    • Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: implications for Alzheimer's disease
    • Stone DJ, Rozovsky I, Moran TE, Anderson CP, Finch CE, et al. (1998) Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: implications for Alzheimer's disease. J. Neurosci. 18: 3180-3185.
    • (1998) J. Neurosci , vol.18 , pp. 3180-3185
    • Stone, D.J.1    Rozovsky, I.2    Moran, T.E.3    Anderson, C.P.4    Finch, C.E.5
  • 44
    • 84862267382 scopus 로고    scopus 로고
    • Gender modulates the APOE-ε4 effect in healthy older adults: convergent evidence from functional brain connectivity and spinal fluid tau levels
    • Damoiseaux JS, Seeley WW, Zhou J, Shirer WR, Coppola G, et al. (2012) Gender modulates the APOE-ε4 effect in healthy older adults: convergent evidence from functional brain connectivity and spinal fluid tau levels. J Neurosci 32: 8254-8262.
    • (2012) J Neurosci , vol.32 , pp. 8254-8262
    • Damoiseaux, J.S.1    Seeley, W.W.2    Zhou, J.3    Shirer, W.R.4    Coppola, G.5
  • 45
    • 0032168460 scopus 로고    scopus 로고
    • Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females
    • Raber JD, Wong D, Buttini M, Orth M, Bellosta S, et al. (1998) Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females. Proc. Natl. Acad. Sci. USA 95: 10914-10919.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10914-10919
    • Raber, J.D.1    Wong, D.2    Buttini, M.3    Orth, M.4    Bellosta, S.5
  • 46
    • 0029926462 scopus 로고    scopus 로고
    • Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease: a possible clue to the higher incidence of Alzheimer disease in women
    • Payami HS, Zareparsi S, Montee KR, Sexton GJ, Kaye JA, et al. (1996) Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease: a possible clue to the higher incidence of Alzheimer disease in women. Am. J. Hum. Genet. 58: 803-811.
    • (1996) Am. J. Hum. Genet , vol.58 , pp. 803-811
    • Payami, H.S.1    Zareparsi, S.2    Montee, K.R.3    Sexton, G.J.4    Kaye, J.A.5
  • 48
    • 0031943549 scopus 로고    scopus 로고
    • Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease
    • Farlow MR, Lahiri DK, Poirer J, Davignon J, Schneider L, et al. (1998) Treatment outcome of tacrine therapy depends on apolipoprotein genotype and gender of the subjects with Alzheimer's disease. Neurology 50: 669-677.
    • (1998) Neurology , vol.50 , pp. 669-677
    • Farlow, M.R.1    Lahiri, D.K.2    Poirer, J.3    Davignon, J.4    Schneider, L.5
  • 49
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI
    • Hixson J, Vernier D, (1990) Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 31: 545-548.
    • (1990) J Lipid Res , vol.31 , pp. 545-548
    • Hixson, J.1    Vernier, D.2
  • 50
    • 2342419515 scopus 로고    scopus 로고
    • Telomere measurement by quantitative PCR
    • Cawthon R, (2002) Telomere measurement by quantitative PCR. Nucl. Acids Res. (2002) 30: e47.
    • (2002) Nucl. Acids Res , vol.30
    • Cawthon, R.1
  • 51
    • 59649089857 scopus 로고    scopus 로고
    • Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study
    • Aviv A, Chen W, Gardner JP, Kimura M, Brimacombe M, et al. (2009) Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study. Am J Epidemiol 169: 323-329.
    • (2009) Am J Epidemiol , vol.169 , pp. 323-329
    • Aviv, A.1    Chen, W.2    Gardner, J.P.3    Kimura, M.4    Brimacombe, M.5
  • 52
    • 0031922795 scopus 로고    scopus 로고
    • Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals
    • Iwama H, Ohyashiki K, Ohyashiki JH, Hayashi S, Yahat N, et al. (1998) Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals. Hum. Genet. 102: 397-402.
    • (1998) Hum. Genet , vol.102 , pp. 397-402
    • Iwama, H.1    Ohyashiki, K.2    Ohyashiki, J.H.3    Hayashi, S.4    Yahat, N.5
  • 53
  • 54
    • 79952964129 scopus 로고    scopus 로고
    • Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress
    • Wolkowitz OM, Mellon SH, Epel ES, Lin J, Dhabhar FS, et al. (2010) Leukocyte telomere length in major depression: correlations with chronicity, inflammation and oxidative stress. Plos One 6: e17837.
    • (2010) Plos One , vol.6
    • Wolkowitz, O.M.1    Mellon, S.H.2    Epel, E.S.3    Lin, J.4    Dhabhar, F.S.5
  • 55
    • 33749534161 scopus 로고    scopus 로고
    • Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging
    • Blackburn EH, Greider CW, Szostak JW, (2006) Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat Med 12: 1133-1138.
    • (2006) Nat Med , vol.12 , pp. 1133-1138
    • Blackburn, E.H.1    Greider, C.W.2    Szostak, J.W.3
  • 57
    • 82755177401 scopus 로고    scopus 로고
    • APOE e4 is associated with longer telomeres, and longer telomeres among e4 carriers predicts worse episodic memory
    • Wikgren M, Karlsson T, Nilbrink T, Nordfjall K, Hultdin J, et al. (2012) APOE e4 is associated with longer telomeres, and longer telomeres among e4 carriers predicts worse episodic memory. Neurobiol Aging 33: 335-344.
    • (2012) Neurobiol Aging , vol.33 , pp. 335-344
    • Wikgren, M.1    Karlsson, T.2    Nilbrink, T.3    Nordfjall, K.4    Hultdin, J.5
  • 58
    • 18244386227 scopus 로고    scopus 로고
    • Rise in insulin resistance is associated with escalated telomere attrition
    • Gardner JP, Li S, Srinivasan SR, Chen W, Kimura M, et al. (2005) Rise in insulin resistance is associated with escalated telomere attrition. Circulation 111: 2171-2177.
    • (2005) Circulation , vol.111 , pp. 2171-2177
    • Gardner, J.P.1    Li, S.2    Srinivasan, S.R.3    Chen, W.4    Kimura, M.5
  • 59
    • 77952527446 scopus 로고    scopus 로고
    • Telomere length trajectory and its determinants in persons with coronary artery disease: Longitudinal findings from the Heart and Soul Study
    • doi: 10.1371
    • Farzaneh-Far R, Lin J, Epel E, Lapham K, Blackburn E, et al. (2010) Telomere length trajectory and its determinants in persons with coronary artery disease: Longitudinal findings from the Heart and Soul Study. Plos One 5(1): e8612 doi:10.1371.
    • (2010) Plos One , vol.5 , Issue.1
    • Farzaneh-Far, R.1    Lin, J.2    Epel, E.3    Lapham, K.4    Blackburn, E.5
  • 60
    • 24144438187 scopus 로고    scopus 로고
    • Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity
    • Imanishi T, Hano T, Nishio I, (2005) Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity. J. Hypertens 23: 1699-1706.
    • (2005) J. Hypertens , vol.23 , pp. 1699-1706
    • Imanishi, T.1    Hano, T.2    Nishio, I.3
  • 61
    • 0027958761 scopus 로고
    • Oestrogen and inhibition of oxidation of low-density lipoproteins in postmenopausal women
    • Sack MN, Rader DJ, Cannon RO, (1994) Oestrogen and inhibition of oxidation of low-density lipoproteins in postmenopausal women. Lancet 343: 269-270.
    • (1994) Lancet , vol.343 , pp. 269-270
    • Sack, M.N.1    Rader, D.J.2    Cannon, R.O.3
  • 62
    • 33750952697 scopus 로고    scopus 로고
    • Activation of estrogen receptor a increases and estrogen receptor b decreases apolipoprotein E expression in the hippocampus in vitro and in vivo
    • Wang JM, Irwin RW, Brinton RD, (2006) Activation of estrogen receptor a increases and estrogen receptor b decreases apolipoprotein E expression in the hippocampus in vitro and in vivo. PNAS 103: 16983-16988.
    • (2006) PNAS , vol.103 , pp. 16983-16988
    • Wang, J.M.1    Irwin, R.W.2    Brinton, R.D.3
  • 63
    • 0034705091 scopus 로고    scopus 로고
    • Estrogen use, APOE, and cognitive decline: evidence of gene-environment interaction
    • Yaffe K, Haan M, Byers A, Tangen C, Kuller L, (2000) Estrogen use, APOE, and cognitive decline: evidence of gene-environment interaction. Neurology 54: 1949-1954.
    • (2000) Neurology , vol.54 , pp. 1949-1954
    • Yaffe, K.1    Haan, M.2    Byers, A.3    Tangen, C.4    Kuller, L.5
  • 64
    • 0029765553 scopus 로고    scopus 로고
    • Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides
    • Miyata M, Smith JD, (1996) Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides. Nat Genet 14: 55-61.
    • (1996) Nat Genet , vol.14 , pp. 55-61
    • Miyata, M.1    Smith, J.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.