Leukocyte telomere length and mortality in the cardiovascular health study

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 66 A, Issue 4, 2011, Pages 421-429

  Fitzpatrick, Annette L ^a   Kronmal, Richard A ^a   Kimura, Masayuki ^b   Gardner, Jeffrey P ^b   Psaty, Bruce M ^a,c,d   Jenny, Nancy S ^e   Tracy, Russell P ^e   Hardikar, Sheetal ^a   Aviv, Abraham ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b University of Medicine and Dentistry of New Jersey Medical School   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d CENTER FOR HEALTH STUDIES   (United States)

^e UNIVERSITY OF VERMONT   (United States)

Author keywords

Cardiovascular disease; Cause of death; Heart failure; Mortality; Telomere

Indexed keywords

AGED; AGING; ARTICLE; BODY MASS; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; COMORBIDITY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; FEMALE; GENETICS; HUMAN; HYPERTENSION; LEUKOCYTE; LONGITUDINAL STUDY; MALE; METABOLISM; MORTALITY; PROSPECTIVE STUDY; SMOKING; STROKE; TELOMERE;

AGED; AGED, 80 AND OVER; AGING; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CAUSE OF DEATH; COMORBIDITY; CORONARY DISEASE; DIABETES MELLITUS; FEMALE; HUMANS; HYPERTENSION; LEUKOCYTES; LONGITUDINAL STUDIES; MALE; PROSPECTIVE STUDIES; SMOKING; STROKE; TELOMERE;

EID: 79957789230     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glq224     Document Type: Article

References (50)

1. Wong JM, Collins K. Telomere maintenance and disease. Lancet. 2003;362:983-988. (Pubitemid 37159296)
2. Blackburn EH. Telomere states and cell fates. Nature. 2000;408:53-56.
3. Aubert G, Lansdorp PM. Telomeres and aging. Physiol Rev. 2008; 88:557-579. (Pubitemid 351522746)
4. Jevapalan JC, Sedivy JM. Cellular senescence and organismal aging. Mech Ageing Dev. 2008;129:467-474.
5. Benetos A, Okuda K, Lajemi M, et al. Telomere length as an indicator of biological aging: the gender effect and relation with pulse pressure and pulse wave velocity. Hypertension. 2001;37:381-385. (Pubitemid 32198997)
6. Nawrot TS, Staessen JA, Gardner JP, et al. Telomere length and possible link to the X-chromosome. Lancet. 2004;363:507-510. (Pubitemid 38229449)
7. Samani NH, Boulthy R, Butler R, et al. Telomere shortening in atherosclerosis. Lancet. 2001;358:472-473. (Pubitemid 32769858)
8. Demissie S, Levy D, Benjamin EJ, et al. Insulin resistance, oxidative stress, hypertension, and leukocyte telomere length in men from the Framingham Heart Study. Aging Cell. 2006;5:325-330. (Pubitemid 44103248)
9. Fitzpatrick AL, Kronmal RA, Gardner JP, et al. Leukocyte telomere length and cardiovascular disease in the Cardiovascular Health Study. Am J Epidemiol. 2007;165:14-21. (Pubitemid 46026204)
10. Brouillette SW, Moore JS, McMahon AD, et al. Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study. Lancet. 2007; 369:107-114. (Pubitemid 46073129)
11. von Zglinicki T, Serra V, Lorenz M, et al. Short telomere length in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor? Lab Invest. 2000;80:1739-1747.
12. Panossian LA, Porter VR, Valenzuela HF, et al. Telomere shortening in T cells correlates with Alzheimer's disease status. Neurolbiol Aging. 2003;24:77-84. (Pubitemid 35454145)
13. Willeit P, Willeit J, Mayr A, et al. Telomere length and risk of incident cancer and cancer mortality. JAMA. 2010;304:69-75.
14. Zee RY, Castonguay AJ, Barton NS, Germer S, Martin M. Mean leukocyte telomere length shortening and type 2 diabetes mellitus: a case-control study. Transl Res. 2010;155:166-169.
15. Terry DF, Nolan VG, Andersen SL, Perls TT, Cawthon R. Association of longer telomeres with better health in centenarians. J Gerontol A Biol Sci Med Sci. 2008;63:809-812.
16. Njajou OT, Hsueh WC, Blackburn EH, et al. Association between telomere length, specific causes of death, and years of healthy life in Health, Aging, and Body Composition, a Population-Based Cohort Study. J Gerontol A Biol Sci Med Sci. 2009;64A:860-864.
17. Cawthon RM, Smith KR, O'Brien E, et al. Association between telo-mere length in blood and mortality in people aged 60 years or older. Lancet. 2003:361:393-395. (Pubitemid 36164975)
18. Honig LS, Schupf N, Lee JH, et al. Shorter telomeres are associated with mortality in those with APOE e4 and dementia. Ann Neurol. 2006;60:181-187. (Pubitemid 44182393)
19. Harris SE, Deary IJ, MacIntyre A, et al. The association between telo-mere length, physical health, cognitive ageing, and mortality in non-demented older people. Neurosci Lett. 2006;406:260-264. (Pubitemid 44311375)
20. Kimura M, Hjelmborg JvB, Gardner JP, et al. Telomere length and mortality: a study of leukocytes in elderly Danish twins. Am J Epidemiol. 2008;167:799-806. (Pubitemid 351451747)
21. Bakaysa SL, Mucci LA, Slagvoom PE, et al. Telomere length predicts survival independent of genetic influences. Aging Cell. 2007;6: 769-774. (Pubitemid 350131045)
22. Astrup AS, Tarnow L, Jorsal A, et al. Telomere length predicts all-cause mortality in patients with type 1 diabetes. Diabetologia. 2010;53: 45-48.
23. Farzaneh-Far R, Cawthon RM, Na B, Browner WS, Schiller NB, Whooley MA. Prognostic value of leukocyte telomere length in patients with stable coronary artery disease: data from the Heart and Soul Study. Arterioscler Thromb Vasc Biol. 2008;28:1379-1384.
24. Martin-Ruiz C, Dickinson HO, Keys B, Rowan E, Kenny RA, Von Zglinicki T. Telomere length predicts poststroke mortality, dementia, and cognitive decline. Ann Neurol. 2006;60:174-180. (Pubitemid 44182392)
25. Martin-Ruiz CM, Gussekloo J, van Heemst D, et al. Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based study. Aging Cell. 2005;4:287-290.
26. Bischoff C, Petersen HC, Graakjaer J, et al. No association between telomere length and survival among the elderly and oldest old. Epidemiology. 2006;17:190-194.
27. Aviv A. The epidemiology of human telomeres: faults and promises. J Gerontol A Biol Sci Med Sci. 2008;63:979-983.
28. Longo DL. Telomere dynamics in aging: much ado about nothing? J Gerontol A Biol Sci Med Sci. 2009;64A:963-964.
29. Kimura M, Gazitt Y, Cao X, Zhao X, Lansdorp PM, Aviv A. Synchrony of telomere length among hematopoietic cells. Exp Hematol. 2010; 38:854-859.
30. Effros RB. Kleemeier Award Lecture 2008 - the canary in the coal mine: telomeres and human health span. J Gerontol A Biol Sci Med Sci. 2009;64:511-515.
31. Fried LP, Borhani NO, Enright P, et al. The Cardiovascular Health Study: design and rationale. Ann Epidemiol. 1991;1:263-276.
32. Ives DG, Fitzpatrick AL, Bild DE, et al. Surveillance and ascertainment of cardiovascular events: the Cardiovascular Health Study. Ann Epidemiol. 1995;5:278-285.
33. Kimura M, Stone RC, Hunt SC, et al. Measurement of telomere length by the Southern blot analysis of terminal restriction fragment lengths. Nat Protoc. 2010;5:1596-1607.
34. Wahl PW, Savage PJ, Psaty BM, Orfanrd TJ, Robbins JA, Tracy RP. Diabetes in older adults: comparison of 1997 American Diabetes Association classification of diabetes mellitus with 1985 WHO clas-sification. Lancet. 1998;352:1012-1015. (Pubitemid 28438572)
35. Psaty BM, Kuller LH, Bild D, et al. Methods of assessing prevalent cardiovascular disease in the Cardiovascular Health Study. Ann Epidemiol. 1995;5:270-277.
36. O'Leary DH, Polak JF, Wolfson SK, et al. Use of sonography to evaluate carotid atherosclerosis in the elderly. The Cardiovascular Health Study CHS Collaborative Research Group. Stroke. 1991;22:1155-1163.
37. Newman AB, Siscovick DS, Manolio TA, et al. Ankle-arm index as a marker of atherosclerosis in the Cardiovascular Health Study. Circulation. 1993;88:837-845. (Pubitemid 23263998)
38. Cushman M, Cornell ES, Howard PR, Bovill EG, Tracy RP. Laboratory methods and quality assurance in the Cardiovascular Health Study. Clin Chem. 1995;41:264-270.
39. Jenny NS, Tracy RP, Ogg MS, et al. In the elderly, interleukin-6 plasma levels and the -174G>C polymorphism are associated with the development of cardiovascular disease. Arterioscler Thromb Vasc Biol. 2002;22:2066-2071. (Pubitemid 36025216)
40. Gazit R, Weissman IL, Rossi DJ. Hematopoietic stem cells and the aging hematopoietic system. Semin Hematol. 2008;45:218-224.
41. Zimmermann S, Martens UM. Telomeres, senescence, and hemato-poietic stem cells. Cell Tissue Res. 2008;331:79-90. (Pubitemid 350265486)
42. Hunt SC, Chen W, Gardner JP, et al. Leukocyte telomeres are longer in African Americans than in whites: the National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study. Aging Cell. 2008;7:451-458. (Pubitemid 351998605)
43. Starr JM, Sheils PG, Harris SE, et al. Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. Mech Ageing. 2008;129: 745-751.
44. Ilmonen P, Kotrschal A, Penn DJ. Telomere attrition due to infection. PLoS ONE. 2009;3(5):e2143. doi:10.1371/journal.pone. 0002143.
45. Pawelee G, Akbar A, Caruso C, et al. Human immunosenescence: is it infectious? Immunol Rev. 2005;205:257-268. (Pubitemid 40780191)
46. Kaplan RC, Fitzpatrick AL, Pollak MN, et al. Insulin-like growth factors and leukocyte telomere length: the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci. 2009;65A:1103-1106.
47. Vasan RS, Demissie S, Kimura M, et al. Association of leukoctyte telomere length with echocardiographic left ventricular mass: the Framingham Heart Study. Circulation. 2009;120:1195-1202.
48. Kuznetsova T, Codd V, Brouilette S, et al. Association between left ventricular mass and telomere length in a population study. Am J Epidemiol. 2010;172:440-450.
49. Aviv A. Telomeres and human somatic fitness. J Gerontol A Biol Sci Med Sci. 2006;61:871-873. (Pubitemid 44260173)
50. Mather KA, Jorm AF, Milburn PJ, Tan X, Easteal S, Christensen H. No associations between telomere length and age-sensitive indicators of physical function in mid and later life. J Gerontol A Biol Sci Med Sci. 2010;65:792-799.