Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines

Journal of Biological Chemistry

Volumn 288, Issue 4, 2013, Pages 2403-2413

  Vartanian, Steffan ^a   Bentley, Carolyn ^a   Brauer, Matthew J ^a   Li, Li ^a   Shirasawa, Senji ^b   Sasazuki, Takehiko ^c   Kim, Jung Sik ^d   Haverty, Pete ^a   Stawiski, Eric ^a   Modrusan, Zora ^a   Waldman, Todd ^d   Stokoe, David ^a  

^a GENENTECH INC   (United States)

^b FUKUOKA UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PROPERTIES; CANCER CELL LINES; CELL LINES; CELL MIGRATION; CELL TRANSFORMATION; COLORECTAL CANCER CELL; ENVIRONMENTAL CUES; FEEDBACK SIGNALING; GENOMIC LOCUS; HUMAN MAMMARY EPITHELIAL CELLS; HUMAN TUMOR CELLS; ISOGENIC CELLS; KNOCK OUTS; SOFT AGAR; TRANSCRIPTIONAL PROGRAM; WILD TYPES;

ALGAE; CELL PROLIFERATION; CELLS; GENE EXPRESSION; POLYSACCHARIDES; TISSUE CULTURE;

SIGNALING;

EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN N RAS; RAF PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; BREAST EPITHELIUM; CANCER CELL CULTURE; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME ACTIVATION; FEEDBACK SYSTEM; GENE DELETION; GENE DOSAGE; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE LOCUS; GENE OVEREXPRESSION; GENETIC MANIPULATION; GENETIC TRANSFORMATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INHIBITION KINETICS; MUTATIONAL ANALYSIS; ONCOGENE K RAS; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING;

CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, RAS; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MUTATION; ONCOGENES; PHENOTYPE; RAS PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 84873854839     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.394130     Document Type: Article

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