Transforming thymidine into a magnetic resonance imaging probe for monitoring gene expression

Journal of the American Chemical Society

Volumn 135, Issue 4, 2013, Pages 1617-1624

  Bar Shir, Amnon ^a   Liu, Guanshu ^a,b   Liang, Yajie ^a   Yadav, Nirbhay N ^a,b   McMahon, Michael T ^a,b   Walczak, Piotr ^a   Nimmagadda, Sridhar ^a   Pomper, Martin G ^a   Tallman, Keri A ^c   Greenberg, Marc M ^c   Van Zijl, Peter C M ^a,b   Bulte, Jeff W M ^a,b,c,d,e   Gilad, Assaf A ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d Johns Hopkins University   (United States)

^e Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PATHWAYS; CHEMICAL EXCHANGE SATURATION TRANSFER; EXCHANGE PROCESS; EXCHANGE RATES; EXCHANGEABLE PROTONS; HERPES SIMPLEX VIRUS; IMAGING AGENT; IMAGING PROBE; IMINO PROTONS; IN-VIVO IMAGING; INTERMEDIATE REGIMES; OPTIMAL PROBE; SYNTHETIC CHEMISTRY; THYMIDINE KINASE; WATER SATURATIONS;

CHEMICAL BONDS; ENZYMES; GENE EXPRESSION; MAGNETIC RESONANCE IMAGING; PROBES; PROTEINS; VIRUSES;

PROTONS;

5 METHYL 5,6 DIHYDROTHYMIDINE; DIHYDROPYRIMIDINE DEHYDROGENASE; PROTON; THYMIDINE DERIVATIVE; THYMIDINE KINASE; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ARTICLE; CHEMICAL BOND; CHEMICAL EXCHANGE SATURATION TRANSFER MAGNETIC RESONANCE IMAGING; CONTROLLED STUDY; GENE EXPRESSION; HERPES SIMPLEX VIRUS 1; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; RAT;

GENE EXPRESSION REGULATION, ENZYMOLOGIC; HERPESVIRUS 1, HUMAN; MAGNETIC RESONANCE IMAGING; MOLECULAR PROBES; THYMIDINE; THYMIDINE KINASE;

EID: 84873851132     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja312353e     Document Type: Article

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