Sensitive CEST agents based on nucleic acid imino proton exchange: Detection of poly(rU) and of a dendrimer-poly(rU) model for nucleic acid delivery and pharmacology

Magnetic Resonance in Medicine

Volumn 49, Issue 6, 2003, Pages 998-1005

  Snoussi, Karim ^a   Bulte, Jeff W M ^a   Guéron, Maurice ^c   Van Zijl, Peter C M ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

^c 217 Traylor Bldg ^*

Author keywords

Dendrimer; Imino proton; MRI; Poly(rU); Proton exchange; RNA; Sensitivity enhancement

Indexed keywords

CYTOLOGY; GENE TRANSFER; MAGNETIC RESONANCE IMAGING; RNA; VISIBILITY;

CHEMICAL EXCHANGE SATURATION TRANSFER; GENE DELIVERY SYSTEMS; IMINO PROTONS; NUCLEIC ACID DELIVERIES; POLY(RU); PROTON EXCHANGE; SENSITIVITY ENHANCEMENT FACTORS; SENSITIVITY ENHANCEMENTS;

DENDRIMERS;

CHEMICAL EXCHANGE SATURATION TRANSFER AGENT; CONTRAST MEDIUM; DENDRIMER; IMINO ACID; NUCLEIC ACID; POLYURIDYLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL INTERACTION; CELL MEMBRANE; CHEMICAL BINDING; CHEMICAL EXCHANGE SATURATION TRANSFER; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTRAST ENHANCEMENT; GENE DELIVERY SYSTEM; IMAGE QUALITY; MATHEMATICAL ANALYSIS; NUCLEIC ACID ANALYSIS; PROTON TRANSPORT; RNA ANALYSIS; SENSITIVITY ANALYSIS; SIGNAL DETECTION; STOICHIOMETRY;

EID: 0038101642     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.10463     Document Type: Article

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