Monitoring thymidine kinase and ganciclovir-induced changes in rat malignant glioma in vivo by nuclear magnetic resonance imaging

Cancer Gene Therapy

Volumn 5, Issue 2, 1998, Pages 101-109

  Poptani, Harish ^a   Puumalainen, Anu Maaria ^a,b   Gröhn, Olli H ^a   Loimas, Sami ^a   Kainulainen, Raija ^a   Ylä Herttuala, Seppo ^a,b   Kauppinen, Risto A ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Diffusion weighted imaging; Gene therapy; Magnetic resonance imaging; Rat brain tumors; Thymidine kinase

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE;

ANIMAL; ARTICLE; BRAIN TUMOR; CANCER TRANSPLANTATION; CELL CULTURE; FEMALE; GENETICS; GLIOMA; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; RADIOGRAPHY; RAT;

ANIMALS; BRAIN NEOPLASMS; FEMALE; GANCICLOVIR; GLIOMA; MAGNETIC RESONANCE IMAGING; MOLECULAR SEQUENCE DATA; NEOPLASM TRANSPLANTATION; RATS; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

EID: 0032020264     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Salcman M. Survival in glioblastoma. Historical prespective. Neurosurgery. 1980;7:435-439.
2. Ram Z, Culver KW, Walbridge S, Blease RM, Oldfield EH. In situ retroviral-mediated gene transfer for the treatment of brain tumours in rats. Cancer Res. 1993;53: 83-88.
3. Culver KW, Ram Z, Walbridge S, Ishii H, Oldfield EH, Blease RM. In vivo gene transfer with retroviral vector producer cells for treatment of experimental brain tumours. Science. 1992;256:1550-1552.
4. Izquierdo M, Cortes M, de Felipe P, et al. Long-term rat survival after malignant brain tumour regression by retroviral gene therapy. Gene Ther. 1995;2:66-69.
5. Oldfield EH, Ram Z, Culver KW, Blease RM, DeVroom HL. Gene therapy for the treatment of brain tumours using intra-tumoural transduction with thymidine kinase gene and intravenous ganciclovir. Hum Gene Ther. 1993; 4:39-69.
6. Namba H, Iwadate Y, Tagawa M, et al. Evaluation of the bystander effect in experimental brain tumors bearing herpes simplex virus-thymidine kinase gene by serial magnetic resonance imaging. Hum Gene Ther. 1996;7:1847-1852.
7. Bi WL, Parysek LM, Warnick R, Stambrook PJ. In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSV tk retroviral gene therapy. Hum Gene Ther. 1993;4:725-731.
8. Maron A, Gustin T, Mottet I, Demure R, Octave JN. Ganciclovir mediated regression of rat brain tumours expressing the herpes simplex virus thymidine kinase imaged by magnetic resonance. J Neurooncol. 1995;24:259-265.
9. Maron A, Gustin T, Le Roux A, et al. Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene: long term follow-up by magnetic resonance imaging. Gene Ther. 1996; 3:315-322.
10. Helmer KG, Dardzinski BJ, Sotak CH. The application of porus-media theory to the investigation of time dependent diffusion in vivo systems. NMR Biomed. 1995;8:297-306.
11. Eis M, Els T, Berlage MH. High resolution quantitative relaxation and diffusion MRI of three different experimental brain tumours in rat. Magn Reson Med. 1995;34:835-844.
12. Laerum OD, Rajewsky MF, Schachner M, Stavrou D, Haglid KG, Haugen A. Phenotypic properties of neoplastic cell lines developed from foetal rat brain cells in culture after exposure to ethylnitrosourea in vivo. Z Krebsforsch. 1977;89:273-295.
13. Mc Knight SL. The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene. Nucleic Acids Res. 1980;8:5949-5964.
14. Miller AD, Buttimore C. Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production. Mol Cell Biol. 1986;6:2985-2902.
15. Ylä-Herttuala S, Luoma J, Viita H, Hiltunen T, Sisto T, Nikkari T. Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidised low density lipoprotein. J Clin Invest. 1995;95:2692-2698.
16. Thorsen F, Visted T, Lehtolainen P, Ylä-Herttuala S, Bjerkvig R. Cell growth and virus production in a replication deficient retrovirus packaging cell line. Int J Cancer. 1997;71:874-880.
17. Price J, Turner D, Cepko C. Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer. Proc Natl Acad Sci USA. 1987;84:150-160.
18. Laerum OD, Rajewsky MF. Neoplastic transformation of fetal rat brain cells in culture following exposure to ethylnitrosourea in vivo. J Natl Cancer Inst. 1975;55:1177-1187.
19. Paxinos G, Watson C. The Rat Brain in Stereotactic Coordinates. San Diego, CA: Academic Press; 1986:Plate 22.
20. Ylä-Herttuala S, Rosenfeld ME, Parthasarthy S, et al. Colocalisation of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of artherosclerotic lesions. Proc Natl Acad Sci USA. 1990;87:6959-6963.
21. Ogawa S, Lee TM, Barrere B. The sensitivity of magnetic resonance image signals of a rat brain to changes in the cerebral venous blood oxygenation. Magn Reson Med. 1993;29:205-210.
22. 2. Prog ISMRM. 1997;5:58. Abstract.
23. 2-weighted MRI and spectroscopy. Magn Reson Med. 1990;14:330-346.
24. Knight RA, Dereski MO, Helpern JA, Ordidge RJ, Chopp M. Magnetic resonance imaging assessment of evolving focal cerebral ischemia: comparison with histopathology in rats. Stroke. 1994;25:1252-1261.
25. Vincent AJPE, Vogels R, Someren GV, et al. Herpes simplex virus thymidine kinase gene therapy for rat malignant brain tumours. Hum Gene Ther. 1996;7:197-205.
26. Wu JK, Cano WG, Meylaerts SAG, Qi P, Vrionis F, Cherington V. Bystander tumoricidal effect in the treatment of experimental brain tumors. Neurosurgery. 1994;35: 1094-1103.
27. Barba D, Hardin J, Ray J, Gage FH. Thymidine kinase-mediated killing of rat brain tumours. J Neurosurg. 1993; 79:729-735.