Efficacy and potential of lactic acid bacteria modulating human health

International Journal of Pharma and Bio Sciences

Volumn 3, Issue 4, 2012, Pages 935-948

  Sharma, Rohit ^a,b   Sanodiya, Bhagwan S ^b   Bagrodia, Deepika ^b   Pandey, Mukeshwar ^c   Sharma, Anjana ^a   Bisen, Prakash S ^a,b  

^a RANI DURGAVATI UNIVERSITY   (India)

^b Plant Biotechnology Laboratory R and D Division Tropilite Foods Pvt Ltd   (India)

^c Xcelris Genomics   (India)

Author keywords

Anti microbial; Anticancerous; Health benefits; Immunomodulation; Lactic acid bacteria; Probiotics and bacteriocins

Indexed keywords

ANTIALLERGIC AGENT; ANTIBIOTIC AGENT; BACTERIAL PROTEIN; BACTERIAL VECTOR; BACTERIOCIN; CARBON DIOXIDE; CYTOKINE; HYPOCHOLESTEROLEMIC AGENT; IMMUNOGLOBULIN; LANTIBIOTIC; LIVE VACCINE; POLYPEPTIDE ANTIBIOTIC AGENT; PROBIOTIC AGENT; VIRUS VECTOR; YOGHURT;

ALLERGIC REACTION; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIULCER ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; ASTHMA; COLON CANCER; CONSTIPATION; CYTOKINE RELEASE; DENTAL CARIES; DIARRHEA; DIET SUPPLEMENTATION; DIGESTION; DISEASE CONTROL; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; ENZYME REGULATION; ESCHERICHIA COLI; FERMENTED PRODUCT; FOOD INDUSTRY; FOOD INTAKE; FOOD PRESERVATION; GASTROINTESTINAL SYMPTOM; HEALTH; HEALTH PROMOTION; HOMEOSTASIS; HUMAN; HYPOCHOLESTEROLEMIA; IMMUNOMODULATION; IMMUNOSTIMULATION; INTESTINE FLORA; LACTIC ACID BACTERIUM; LACTOBACILLUS DELBRUECKII; LACTOSE INTOLERANCE; LIPID BILAYER; NONHUMAN; NUTRIENT; OENOCOCCUS OENI; PEDIOCOCCUS PARVULUS; RESPIRATORY TRACT INFECTION; RHINITIS; SOYBEAN MILK; STOMACH ULCER; STREPTOCOCCUS THERMOPHILUS; TETRAGENOCOCCUS HALOPHILUS; UROGENITAL TRACT INFECTION;

EID: 84873840150     PISSN: None     EISSN: 09756299     Source Type: Journal    
DOI: None     Document Type: Article

References (102)

1. Salminen S, Nybom S, Meriluoto J, Collado MC, Vesterlund S, El-Nezami H, Interaction of probiotics and pathogensbenefits to human health. Curr Opin Biotechnol, 21 (2): 157-167, (2010).
2. Tuohy KM, Probert HM, Smejkal CW, Gibson GR, Review: Using probiotics and probiotics to improve gut health. Drug Discov Today, 8 (15): 692-700, (2003).
3. Khalid K, An overview of lactic acid bacteria. Int J Biosci, 1 (3): 1-13, (2011).
4. Schrezenmeir J, de Vrese M, Probiotics, prebiotics, and synbiotics - approaching a definition. Am J Clin Nutr, 73 (2): 361S-364S, (2001).
5. Carol AR, Leon MTD, Horizontal gene transfer amongst probiotic lactic acid bacteria and other intestinal microbiota: what are the possibilities? A review. Arch Microbiol, 193 (3): 157-168, (2010).
6. Carr FJ, Hill D, Maida N, The lactic acid bacteria: A literature survey. Crit. Rev. Microbiol, 28 (4): 281-370, (2002).
7. Derek AA, Joost VDB, Inge MKM, Pronk JT, van Maris AJ, Anaerobic homolactate fermentation with Saccharomyces cerevisiae results in depletion of ATP and impaired metabolic activity. FEMS Yeast Res, 9 (3): 349-357, (2009).
8. Jin YL, Ai HL, Cheng J, Yang WM, First description of a novel Weissella species as an opportunistic pathogen for rainbow trout Oncorhynchus mykiss (Walbaum) in China. Vet Microbiol, 136 (3-4): 314-320, (2009).
9. Holzapfel WH, Haberer P, Geisen R, Bjorkroth J, Schillinger U, Taxonomy and important features of probiotic microorganisms in food nutrition. Am J Clin Nutr, 73: 365S-373S, (2001).
10. Ali AA, Isolation and identification of lactic acid bacteria from raw cow milk in Khartoum State, Sudan. Int J Dairy Sci, 6: 66-71, (2011).
11. Liu SQ, Review article: Practical implications of lactate and pyruvate metabolism by lactic acid bacteria in food and beverage fermentations. Int J Food Microbiol, 83 (2): 115-131, (2003).
12. O'Sullivan L, Ross RP, Hill C, Review: Potential of bacteriocin-producing lactic acid bacteria for improvements in food safety and quality. Biochimie, 84 (5-6): 593-604, (2002).
13. Deguchi Y, Morishita T, Mutai M, Comparative studies on synthesis of water soluble vitamins among human species of bifidobacteria. Agric Biol Chem, 49: 13-29, (1985).
14. Khay EIO, Idaomar M, Castro LMP, Bernárdez PF, Senhaji NS, Abrini J, Antimicrobial activities of the bacteriocins like substances produced by lactic acid bacteria isolated from Moroccan dromedary milk. Afr J Biotechnol, 10 (51): 10447-10455, (2011).
15. Saranya S, Hemashenpagam, Antagonistic activity and antibiotic sensitivity of Lactic acid bacteria from fermented dairy products. Adv Appl Sci Res, 2 (4): 528-534, (2011).
16. Olaoye OA, Onilude AA, Quantitative estimation of antimicrobials produced by Lactic Acid Bacteria isolated from Nigerian beef. Int Food Res J, 18 (3): 1155-1161, (2011).
17. Rodriguez E, Arques JL, Rodriguez R, Nunez M, Medina M, Reuterin production by lactobacilli isolated from pig faeces and evaluation of probiotic traits. Lett Appl Microbiol, 37 (3): 259-263, (2003).
18. Hassan AN, Awad S, Application of exopolysaccharide-producing cultures in reduced-fat Cheddar cheese: cryoscanning electron microscopy observations. J Dairy Sci, 88 (12): 4214-4220, (2005).
19. Welman AD, Maddox IS, Exopolysaccharides from lactic acid bacteria: perspectives and challenges. Trends Biotechnol, 21 (6): 269-274, (2003).
20. Prakash S, Tomaro-Duchesneau C, Saha S, Cantor A, The Gut Microbiota and Human Health with an Emphasis on the Use of Microencapsulated Bacterial Cells. J Biomed Biotech, doi:10.1155/2011/981214, (2011).
21. Bernardeau M, Vernoux JP, Henri- Dubernet S, Guequen M, Safety assessment of dairy microorganisms: the Lactobacillus genus. Int J Food Microbiol, 126 (3): 278-285, (2008).
22. Martin RS, Langa C, Reviriego E, Jimínez E, Marín ML, Xaus J, Fernández L, Rodríguez JM, Human milk is a source of lactic acid bacteria for the infant gut. J. Pediatr. 143 (6):754-758, (2003).
23. Bederska-Lojewska D, Pieszka M, Modulating gastrointestinal Microflora of pigs through nutrition using feed additives. Ann Anim Sci, 11 (3): 333-355, (2011).
24. O'Donnell MM, Forde BM, Neville B, Ross PR, O'Toole PW, Carbohydrate catabolic flexibility in the mammalian intestinal commensal Lactobacillus ruminis revealed by fermentation studies aligned to genome annotations. Microb Cell Fact, 10: S1-S12, (2011).
25. Devirgiliis C, Barile S, Perozzi G, Antibiotic resistance determinants in the interplay between food and gut microbiota. Genes Nutr, 6: 275-284, (2011).
26. Fernandez R, Sridhar M, Sridhar N, Effect of Lactic Acid Bacteria Administered Orally on Growth Performance of Penaeus indicus (H. Milne Edwards) Juveniles. Res J Microbiol, 6 (5): 466-479, (2011).
27. Sbordone L, Bortolaia C, Oral microbial biofilms and plaque-related diseases: microbial communities and their role in the shift from oral health to disease. Clin Oral Investig, 7 (4):181-188, (2003).
28. Prameela K, Mohan CM, Smita PV, Kumar SS, Sreelatha R, Hemalatha APJ, Partial purification and chatecterization of bacteriocin produced by Lactobacillus plantarum and its antibacterial activity. J Pharm Res, 4 (8): 2563-2565, (2011).
29. Coda R, Cassone A, Rizzello CG, Nionelli L, Cardinali G, Gobbeti M, Antifungal Activity of Wickerhamomyces anomalus and Lactobacillus plantarum during Sourdough Fermentation: Identification of Novel Compounds and Long-Term Effect during Storage of Wheat Bread. Appl Environ Microb, 77 (10): 3484-3492, (2011).
30. Oluwafemi F, Adetunji AF, Antimicrobial activities of lactic acid bacteria isolated from traditionally- fermented maize (ogi) against Candida albicans. J Appl Biosci, 41: 2820-283, (2011).
31. Arokiyamary A, Sivakumar PK, Antibacterial activity of Bacterocin producing Lactobacillus sp., isolated from traditional milk products. Curr Bot, 2 (3): 05-08, (2011).
32. Akpinar A, Yerlikaya O, Kili S, Antimicrobial activity and antibiotic resistance of Lactobacillus delbrueckii ssp. bulgaricus and Streptococcus thermophilus strains isolated from Turkish homemade yoghurts. Afr J Microbiol Res, 5 (6): 675-682, (2011).
33. Srinivasan P, Khan KA, Perumal UR, Kumar RV, Suganya K, Rajalakshmi M, Invitro Anti-bacterial activity of Lactobacillus plantarum isolated from soy milk. Int J Pharm Bio Sci, 3 (3) 209-219, 2012.
34. Bilkova A, Sepova HK, Bilka F, Balazova A, Bacteriocins produced by lactic acid bacteria. Ceska Slov Farm, 60 2 65-72, (2011).
35. McAuliffe O, Ross RP, Hill C, Lantibiotics: structure, biosynthesis and mode of action. FEMS Microbiol Rev, 25 (3): 285-308, (2001).
36. Morency H, Mota-Meira M, LaPointe G, Comparison of the activity spectra against pathogens of bacterial strains producing a mutacin or a lantibiotic. Can J Microbiol 47 (4): 322-331, (2001).
37. Suskovic J, Kos B, Beganovic J, Srecko M, Blazenka K, Jasna B, Antimicrobial Activity of Lactic Acid Bacteria. Food Technol Biotechnol 48 (3): 296-307, (2010).
38. Cotter PD, Hill C, Ross RP, Bacterial lantibiotics: strategies to improve therapeutic potential. Curr Protein Pept Sci, 6 (1): 61-75, (2005).
39. Chen H, Hoover DG, Bacteriocins and their food applications. Compr Rev Food Sci, 2: 82-110, (2003).
40. Piper C, Hill C, Cotter PD, Ross PR, Bioengineering of a Nisin A-producing Lactococcus lactis to create isogenic strains producing the natural variants Nisin F, Q and Z Microbial Biotechnol, 4 (3): 375-382, (2011).
41. Zendo T, Fukao M, Ueda K, Higuchi T, Nakayama J, Sonomoto K, Identification of the lantibiotic nisin Q, a new natural nisin variant produced by Lactococcus lactis 61-14 isolated from a river in Japan. Biosci Biotechnol Biochem 67 (7): 1616-1619, (2003).
42. Wiedemann I, Benz R, Sahl HG, Lipid IImediated pore formation by the peptide antibiotic nisin: a black lipid membrane study. J Bacteriol, 186 (10): 3259-3261, (2004).
43. Mythili RS, Sathiavelu A, Recovery of Bacteriocin (NISIN) from Lactococcus lactis and testing its ability to increase the shelf life of vegetables (Carrot and Beans). Res J Biol Sci, 5 (11): 727-730, (2010).
44. Phumkhachorn P, Rattanachaikunsopon P, Bacteriophage specific to nisin producing- Lactococcus lactis subsp. lactis TFF221, a starter culture inThai fermented food. Afr J Microbiol Res, 5 (10): 1203-1210, (2011).
45. Sandre C, Gleizes A, Forestier F, Gorges-Kergot R, Chilmonczyk S, Léonil J, Moreau MC, Labarre C, A peptide derived from bovine betacasein modulates functional properties of bone marrow-derived macrophages from germfree and human flora-associated mice. J Nutr, 131 (11): 2936-2942, (2001).
46. Premalatha M, Dhasarathan P, Probiotic Action of Lactobacillus Isolated from the Milk Sample against Some Human Pathogens. Res J Immunol, 4 (1): 31-37, (2011).
47. Wells J, Mucosal Vaccination and Therapy with Genetically Modified Lactic Acid Bacteria. Ann Rev Food Sci Technol, 2: 423-445, (2011).
48. Izumo T, Ida M, Maekawa T, Yuichi F, Yoshinori K, Yoshinobu K, Comparison of the Immunomodulatory effects of live and heat killed Lactobacillus pentosus S-PT84. J Health Sci, 57 (3): 304-310, (2011).
49. Foligne B, Deutsch SM, Breton J, Cousin FJ, Dewulf J, Samson M, Pot B, Jan G, Promising Immunomodulatory effects of selected strains of dairy propionibacteria as evidenced in vitro and in vivo. Appl Environ Microbiol, 76 (24): 8259-8264, (2010).
50. Salminen S, Bouley C, Boutron-Rusult MC, Cummings JH, Franck A, Gibson GR, Isolauri E, Moreau MC, Roberfroid M, Rowland I, Functional food science and gastrointestinal physiology and function. Brit J Nutr, 80 (S1): S147-5171, (1998).
51. Kaila M, Isolauri E, Soppi E, Virtanen E, Laine S, Arvilommi H, Enhancement of the circulating antibody secreting cell response in human diarrhoea by a human Lactobacillus strain. Pediatr Res, 32 (2): 141-144, (1992)
52. Isolauri E, Majamea H, Arvola T, Rantala I, Virtanen E, Arvilommi H, Lactobacillus strain GG reverses increases intestinal permeability induced by cow milk in suckling rats. Gastroenterology, 105 (6): 1643-1650, (1993).
53. Makino S, Ikegami S, Kano H, Sashihara T, Sugano H, Horiuchi H, Saito T, Oda M, Immunomodulatory effects of polysaccharides produced by Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1. J Dairy Sci, 89 (8): 2873-2881, (2006).
54. Masuda S, Yamaguchi H, Kurokawa T, Shirakami T, Tsuji RF, Nishimura I, Immunomodulatory effect of halophilic lactic acidbacterium Tetragenococcus halophilus Th221 from soy sauce moromi grown in high-salt medium. Int J Food Microbiol, 121 (3): 245-252, (2008).
55. Foligne B, Dewulf J, Breton J, Claisse O, Lonvaud-Funel A, Pot B, Probiotic properties of non-conventional lactic acid bacteria: immunomodulation by Oenococcus oeni. Int J Food Microbiol, 140 (2-3): 136-145, (2010).
56. Botic T, Klingberg TD, Weingartl H, Cencic A, A novel eukaryotic cell culture model to study antiviral activity of potential probiotic bacteria. Int J Food Microbiol, 115 (2): 227-234, (2007).
57. Isolauri E, Probiotics in human disease. Am J Clin Nutr 73 (6): 1142S-1146S, (2007).
58. Pant N, Marcotte H, Brussow H, Svensson L, Hammarström L, Effective prophylaxis against rotavirus diarrhea using a combination of Lactobacillus rhamnosus GG and antibodies. BMC Microbiol, 7: 86, (2007).
59. Zhang M, Wu X, Lee AJ, Jin W, Chang M, Wright A, Imaizumi T, Sun SC, Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD. J Biol Chem, 283 (27): 18621-18626, (2008).
60. Versalovic J, Iyer C, Ping Lin Y, Yanhong H, Walter D, Commensalderived probiotics as anti-inflammatory agents. Microb Ecol Health Dis, 20 (8): 86-93, (2008).
61. Moreno de LeBlanc A, del Carmen S, Zurita-Turk M, Santos Rocha C, van de Guchte M, Azevedo V, Miyoshi A, Leblanc JG, Importance of IL- 10Modulation by Probiotic Microorganisms in Gastrointestinal Inflammatory Diseases. ISRN Gastroenterol doi:10.5402/2011/892971, (2011).
62. Liao CL, Huang HY, Sheen LY, Chou CC, Anti-inflammatory activity of soymilk and fermented soymilk prepared with lactic acid bacteria and bifidobacterium. J Food Drug Anal, 18 (3): 202-207, (2010).
63. Park EK, Sung JH, Trinh HT, Bae EA, Yun HK, Hong SS, Kim DH, Lactic acid bacterial fermentation increases the antiallergic effects of Ixeris dentate. J Microb Biot, 18 (2): 308-313, (2008).
64. Kadooka K, Imahayashi A, Koiso A, Yamashita M, Teruya K, Matsumoto T, Hasegawa T, Morimatsu F, Katakura Y, Establishment of a novel method of screening anti-allergic lactic acid bacteria. Biosci Biotechnol Biochem, 75 (5): 1016-1018, (2011).
65. Peng S, Lin JY, Lin MY, Antiallergic Effect of Milk Fermented with Lactic Acid Bacteria in a Murine Animal Model. J Agric Food Chem, 55 (13): 5092-5096, (2007).
66. Ishida Y, Nakamura F, Kanzato H Sawada D, Hirata H, Nishimura A, Kajimoto O, Fujiwara S, Clinical effects of Lactobacillus acidophilus strain L-92 on perennial allergic rhinitis: a double-blind, placebocontrolled study. J Dairy Sci, 88 (2): 527-533, (2005).
67. Kalliomaki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E, Probiotics in primary prevention of atopic disease: a randomized placebocontrolled trial. Lancet, 357 (9262): 1076-1079, (2001).
68. Gao D, Zhu G, Gao Z, Liu Z, Wang L, Guo W, Antioxidative and hypolipidemic effects of lactic acid bacteria from pickled Chinese cabbage. J Med Plants Res, 5 (8): 1439-1446, (2011).
69. Lavanya B, Sowmiya S, Balaji S, Muthuvelan B, Screening and Characterization of Lactic Acid Bacteria from Fermented Milk. British J Dairy Sci, 2 (1): 5-10, (2011).
70. Guslandi M, Giollo P, Testoni PA, A pilot trial of Saccharomyces boulardii in ulcerative colitis. Eur J Gastroenterol Hepatol, 15 (6): 697-698, (2003).
71. Jain S, Yadav H, Sinha PR, Antioxidant and cholesterol assimilation activities of selected lactobacilli and lactococci cultures. J Dairy Res, 76 (4): 385-391, (2009).
72. Koiche M, Dilmi BA, Selection of local extremophile lactic acid bacteria with high capacity to degrade lactose: Potential use to reduce intolerance to lactose in vitro. Afr J Biotechnol, 9 (11): 1635-1640, (2010).
73. Pato U, Surono IS, Koesnandar, Hosono A, Hypocholesterolemic effect of indigenous dadih lactic acid bacteria by deconjugation of bile salts. Asian- Aust J Anim Sci, 17 (12): 1741-1745, (2004).
74. Salminen S, Tanaka R, Annual review on cultured milks and probiotics. IDF Nutrition Newsletter, 4: 47-50, (1995).
75. Nagaoka M, Hashimoto S, Watanabe T, Yokokura T, Mori Y, Anti-ulcer effects of lactic acid bacteria and their cell wall polysaccharides. Biol Pharm Bull, 17: 1012-1017, (1994).
76. Mizgerd JP, Acute lower respiratory tract infection. N Engl J Med, 358 (7): 716-727, (2008).
77. Villena J, Leonor S. Oliveira M, Salva S, Alvarez S, Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges. Int. Immunopharmaco. doi:10.1016/j.intimp, (2011).
78. Eschenbach DA, Davick PR, Williams SJ, Klebanoff SJ, Young-Smith K, Critchlow CM, Hilmes KK, Prevalence of hydrogen peroxideproducing Lactobacillus species in normal women and women with bacterial vaginosis. J Clin Microbiol, 27 (2): 251-256, (1989).
79. Hilton E, Isenberg HD, Alperstein P, France K, Borenstein MT, Ingestion of yogurt containing Lactobacillus acidophilus as prophylaxis for candidal vaginitis. Ann Int Medicine, 116 (5): 353-357, (1992).
80. Hajela N, Nair GB, Ganguly NK, Are probiotics a feasible intervention for prevention of diarrhoea in the developing world? Gut Pathogens, 2:10, (2010).
81. Gamboa-Dominguez A, Ubbelohde T, Saqui-Salces M, Romano-Mazzoti L, Cervantes M, Dominguez-Fonseca C, de la Luz Estreber M, M.Ruiz-Palacois G, Salt and stress synergize H. pyloriinduced gastric lesions, cell proliferation, and p21 expression in Mongolian gerbils. Dig Dis Sci, 52 (6): 1517-1526, (2007).
82. Rodriguez C, Medici M, Mozzi F, Font de Valdez G. Therapeutic effect of Streptococcus thermophilus CRL 1190- fermented milk on chronic gastritis. World J Gastroenterol 16 (13): 1622-1630, (2010).
83. Wallace JL, Nonsteroidal antiinflammatory drugs and gastroenteropathy: the second hundred years. Gastroenterology, 112 (3): 1000-1016, (1997).
84. Daniel G, Roussel Y, Kleerebezem M, Pot B, Recombinant lactic acid bacteria as mucosal biotherapeutic agents. Trends Biotechnol, 29 (10): 499-508, (2011).
85. LeBlanc JG, de LeBlanc A de M, Perdigón G, Anderson M, Tatiana R, Luis BH, Philippe L, Fernando S, Vasco A, Anti-inflammatory properties of lactic acid bacteria: Current knowledge, applications and prospects. Anti-Inf Agents in Med Chem, 7 (3): 148-154, (2008).
86. Wells J, Mucosal Vaccination and Therapy with Genetically Modified Lactic Acid Bacteria. Ann Rev Food Sci Technol, 2: 423-445, (2011).
87. Mercenier A, Müller-Alouf H, Grangette C, Lactic acid bacteria as live vaccines. Curr Issues Mol Biol, 2 (1): 17-25, (2000).
88. Detmer A, Glenting J, Live bacterial vaccines- a review and identification of potential hazards. Microbial Cell Fact, 5:23, (2006).
89. Medaglini D, Pozzi G, King TP, Mucosal and systemic immune responses to a recombinant protein expressed on the surface of the oral commensal bacterium Streptococcus gordonii after oral colonisation. Proc Natl Acad Sci USA, 92 (15): 6868-6872, (1995).
90. Lamm ME, Interaction of antigens and antibodies at mucosal surfaces. Ann Rev Microbiol 51: 311-340, (1997).
91. Walker RI, New strategies for using mucosal vaccination to achieve more effective immunisation. Vaccine, 12 (5): 387-400, (1994).
92. Formal SB, Baron LS, Kopecko DJ, Washington O, Powell C, Life CA, Construction of a potential bivalent vaccine strain: introduction of Shigella sonnei form I antigen genes into the galE Salmonella typhi Ty21a typhoid vaccine strain. Infect Immun, 34 (3): 746-750, (1981).
93. Tarahomjoo S, Development of vaccine delivery vehicles based on lactic acid bacteria. Mol Biotechnol, 51 (2): 183-199, 2012.
94. Pouwels PH, Leer RJ, Shaw M, Heijne den Bak-Glashouwer MJ, Tielen FD, Smit E, Martinez B, Jore J, Conway PL, Lactic acid bacteria as antigen delivery vehicles for oral immunization purposes. Int J Food Microbiol, 41 (2):155-167, (1998).
95. Lee P, Biocontainment strategies for live lactic acid bacteria vaccine vectors. Bioeng Bugs, 1 (1): 75-77, (2010).
96. Fraissl L, Leitner R, Missbichler A, Novel formulation of neutral lactase improves digestion of dairy products in case of lactose intolerance. Clin Transl Allergy, 1:104, (2011).
97. Srividya AR, Vishnuvarthan VJ, Probiotic: a rational approach to use Probiotic as medicine IJPFR, 1 (1): 126-134, (2011).
98. Qi-Wei Y, Chun-Feng W, Gui-Lian Y, The Research Progress of Anti-tumor of Lactic Acid bacteria. Food Sci, 32 (9): 303-306, (2011).
99. Wollowski I, Rechkemmer G, Pool-Zobe BL, Protective role of probiotics and prebiotics in colon cancer. Am J Clin Nutr, 73 (2): 451S-455S, (2001).
100. Rowland IR, Rumney CJ, Coutts JT, Lievense LC, Effect of Bifidobacterium longum and inulin on gut bacterial metabolism and carcinogen-induced aberrant crypt foci in rats. Carcinogenesis, 19 (2): 281-285, (1998).
101. Liu CF, Pan TM, In vitro effects of lactic acid bacteria on cancer cell viability and antioxidant activity. J Food Drug Anal, 18 (2): 77-86, (2010).
102. Kumar M, Kumar A, Nagpal R, Mohania D, Behare P, Verma V, Kumar P, Poddar D, Aggarwal PK, Henry CJ, Jain S, Yadav H, Cancer-preventing attributes of probiotics: An update. Int J Food Sci Nutr, 61 (5): 473-496, (2010).