CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling

Journal of Clinical Investigation

Volumn 123, Issue 1, 2013, Pages 299-314

  Faber, Katrin ^a   Bullinger, Lars ^a   Ragu, Christine ^b   Garding, Angela ^a   Mertens, Daniel ^a   Miller, Christina ^a   Martin, Daniela ^a   Walcher, Daniel ^a   Döhner, Konstanze ^a   Döhner, Hartmut ^a   Claus, Rainer ^c   Plass, Christoph ^c   Sykes, Stephen M ^b   Lane, Steven W ^d   Scholl, Claudia ^a   Fröhling, Stefan ^a,c  

^a UNIVERSITY OF ULM   (Germany)

^b HARVARD MEDICAL SCHOOL   (United States)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

KRUPPEL LIKE FACTOR 4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; TRANSCRIPTION FACTOR CDX2;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL DIFFERENTIATION; COLON CANCER; COMPUTER MODEL; DISEASE ASSOCIATION; EPIGENETIC REPRESSION; HEMATOPOIETIC CELL; LEUKEMIA CELL; LEUKEMOGENESIS; MODULATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; COLONIC NEOPLASMS; GENE EXPRESSION REGULATION, LEUKEMIC; HEMATOPOIETIC STEM CELLS; HL-60 CELLS; HOMEODOMAIN PROTEINS; HUMANS; K562 CELLS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LEUKEMIA, MYELOID, ACUTE; MICE; ORGAN SPECIFICITY; PPAR GAMMA; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; U937 CELLS;

EID: 84873811823     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI64745     Document Type: Article

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