Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 3, 2004, Pages 817-822

  Rawat, Vijay P S ^a   Cusan, Monica ^a   Deshpande, Aniruddha ^a   Hiddemann, Wolfgang ^a   Quintanilla Martinez, Leticia ^b   Humphries, R Keith ^c   Bohlander, Stefan K ^a   Feuring Buske, Michaela ^a   Buske, Christian ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN; RETROVIRUS VECTOR;

ACUTE GRANULOCYTIC LEUKEMIA; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CDX2 GENE; CHIMERA; CHROMOSOME ANALYSIS; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; EMBRYO; ETV6 CDX2 GENE; FUSION GENE; GENE EXPRESSION; GENE LOCATION; HOMEOBOX; LYMPHATIC LEUKEMIA; LYMPHOMA; MOUSE; MYELOID LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; PROTO ONCOGENE;

ANIMALS; BONE MARROW TRANSPLANTATION; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 13; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GENES, HOMEOBOX; HOMEODOMAIN PROTEINS; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOPLASM PROTEINS; ONCOGENE PROTEINS, FUSION; TRANS-ACTIVATORS; TRANSLOCATION, GENETIC;

ANIMALIA; MURINAE; UNIDENTIFIED RETROVIRUS;

EID: 1642474256     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0305555101     Document Type: Article

References (46)

1. Rowley, J. D. (1999) Semin. Hematol. 36, 59-72.
2. Bohlander, S. K. (2000) Cytogenet. Cell Genet. 91, 52-56.
3. Look, A. T. (1997) Science 278, 1059-1064.
4. Pineault, N., Buske, C., Feuring-Buske, M., Abramovich, C., Rosten, P., Hogge, D. E., Aplan, P. D. & Humphries, R. K. (2003) Blood 101, 4529-4538.
5. Kroon, E., Krosl, J., Thorsteinsdottir, U., Baban, S., Buchberg, A. M. & Sauvageau, G. (1998) EMBO J. 17, 3714-3725.
6. Castilla, L. H., Garrett, L., Adya, N., Orlic, D., Dutra, A., Anderson, S., Owens, J., Eckhaus, M., Bodine, D. & Liu, P. P. (1999) Nat. Genet. 23, 144-146.
7. Odero, M. D., Carlson, K., Calasanz, M. J., Lahortiga, I., Chinwalla, V. & Rowley, J. D. (2001) Genes Chromosomes Cancer 31, 134-142.
8. Million, R. P., Aster, J., Gilliland, D. G. & Van Etten, R. A. (2002) Blood 99, 4568-4577.
9. Schwaller, J., Frantsve, J., Aster, J., Williams, I. R., Tomasson, M. H., Ross, T. S., Peeters, P., Van Rompaey, L., Van Etten, R. A., Ilaria, R., Jr., et al. (1998) EMBO J. 17, 5321-5333.
10. Tomasson, M. H., Sternberg, D. W., Williams, I. R., Carroll, M., Cain, D., Aster, J. C., Ilaria, R. L., Jr., Van Etten, R. A. & Gilliland, D. G. (2000) J. Clin. Invest. 105, 423-432.
11. Iijima, Y., Okuda, K., Tojo, A., Tri, N. K., Setoyama, M., Sakaki, Y., Asano, S., Tokunaga, K., Kruh, G. D. & Sato, Y. (2002) Oncogene 21, 4374-4383.
12. Wai, D. H., Knezevich, S. R., Lucas, T., Jansen, B., Kay, R. J. & Sorensen, P. H. (2000) Oncogene 19, 906-915.
13. Golub, T. R., Barker, G. F., Bohlander, S. K., Hiebert, S. W., Ward, D. C., Bray-Ward, P., Morgan, E., Raimondi, S. C., Rowley, J. D. & Gilliland, D. G. (1995) Proc. Natl. Acad. Sci. USA 92, 4917-4921.
14. Chase, A., Reiter, A., Burci, L., Cazzaniga, G., Biondi, A., Pickard, J., Roberts, I. A., Goldman, J. M. & Cross, N. C. (1999) Blood 93, 1025-1031.
15. Peeters, P., Wlodarska, I., Baens, M., Criel, A., Selleslag, D., Hagemeijer, A., Van den Berghe, H. & Marynen, P. (1997) Cancer Res. 57, 564-569.
16. Andreasson, P., Schwaller, J., Anastasiadou, E., Aster, J. & Gilliland, D. G. (2001) Cancer Genet. Cytogenet. 130, 93-104.
17. Bernardin, F., Yang, Y., Cleaves, R., Zahurak, M., Cheng, L., Civin, C. I. & Friedman, A. D. (2002) Cancer Res. 62, 3904-3908.
18. Wlodarska, I., Baens, M., Peeters, P., Aerssens, J., Mecucci, C., Brock, P., Marynen, P. & Van den Berghe, H. (1996) Cancer Res. 56, 2655-2661.
19. Patel, N., Goff, L. K., Clark, T., Ford, A. M., Foot, N., Lillington, D., Hing, S., Pritchard-Jones, K., Jones, L. K. & Saha, V. (2003) Br. J. Haematol. 122, 94-98.
20. Cools, J., Mentens, N., Odero, M. D., Peeters, P., Wlodarska, I., Delforge, M., Hagemeijer, A. & Marynen, P. (2002) Blood 99, 1776-1784.
21. Penas, E. M., Cools, J., Algenstaedt, P., Hinz, K., Seeger, D., Schafhausen, P., Schilling, G., Marynen, P., Hossfeld, D. K. & Dierlamm, J. (2003) Genes Chromosomes Cancer 37, 79-83.
22. Knoepfler, P. S. & Kamps, M. P. (1995) Mol. Cell. Biol. 15, 5811-5819.
23. Shanmugam, K., Green, N. C., Rambaldi, I., Saragovi, H. U. & Featherstone, M. S. (1999) Mol. Cell. Biol. 19, 7577-7588.
24. Buske, C., Feuring-Buske, M., Antonchuk, J., Rosten, P., Hogge, D. E., Eaves, C. J. & Humphries, R. K. (2001) Blood 97, 2286-2292.
25. Buske, C., Feuring-Buske, M., Abramovich, C., Spiekermann, K., Eaves, C. J., Coulombel, L., Sauvageau, G., Hogge, D. E. & Humphries, R. K. (2002) Blood 100, 862-868.
26. Feuring-Buske, M., Frankel, A. E., Alexander, R. L., Gerhard, B. & Hogge, D. E. (2002) Cancer Res. 62, 1730-1736.
27. Pineault, N., Helgason, C. D., Lawrence, H. J. & Humphries, R. K. (2002) Exp. Hematol. 30, 49-57.
28. Silberg, D. G., Sullivan, J., Kang, E., Swain, G. P., Moffett, J., Sund, N. J., Sackett, S. D. & Kaestner, K. H. (2002) Gastroenterology 122, 689-696.
29. Brooke, N. M., Garcia-Fernandez, J. & Holland, P. W. (1998) Nature 392, 920-922.
30. van den Akker, E., Forlani, S., Chawengsaksophak, K., de Graaff, W., Beck, F., Meyer, B. I. & Deschamps, J. (2002) Development (Cambridge, U.K.) 129, 2181-2193.
31. Isaacs, H. V., Pownall, M. E. & Slack, J. M. (1998) EMBO J. 17, 3413-3427.
32. Buske, C. & Humphries, R. K. (2000) Int. J. Hematol. 71, 301-308.
33. Sauvageau, G., Lansdorp, P. M., Eaves, C. J., Hogge, D. E., Dragowska, W. H., Reid, D. S., Largman, C., Lawrence, H. J. & Humphries, R. K. (1994) Proc. Natl. Acad. Sci. USA 91, 12223-12227.
34. Golub, T. R., Slonim, D. K., Tamayo, P., Huard, C., Gaasenbeek, M., Mesirov, J. P., Coller, H., Loh, M. L., Downing, J. R., Caligiuri, M. A., et al. (1999) Science 286, 531-537.
35. Debernardi, S., Lillington, D. M., Chaplin, T., Tomlinson, S., Amess, J., Rohatiner, A., Lister, T. A. & Young, B. D. (2003) Genes Chromosomes Cancer 37, 149-158.
36. Ferrando, A. A., Armstrong, S. A., Neuberg, D. S., Sallan, S. E., Silverman, L. B., Korsmeyer, S. J. & Look, A. T. (2003) Blood 102, 262-268.
37. Yeoh, E. J., Ross, M. E., Shurtleff, S. A., Williams, W. K., Patel, D., Mahfouz, R., Behm, F. G., Raimondi, S. C., Relling, M. V., Patel, A., et al. (2002) Cancer Cell 1, 133-143.
38. Thorsteinsdottir, U., Kroon, E., Jerome, L., Blasi, F. & Sauvageau, G. (2001) Mol. Cell. Biol. 21, 224-234.
39. Lorentz, O., Duluc, I., Arcangelis, A. D., Simon-Assmann, P., Kedinger, M. & Freund, J. N. (1997) J. Cell Biol. 139, 1553-1565.
40. Charite, J., de Graaff, W., Consten, D., Reijnen, M. J., Korving, J. & Deschamps, J. (1998) Development (Cambridge, U.K.) 125, 4349-4358.
41. Subramanian, V., Meyer, B. I. & Gruss, P. (1995) Cell 83, 641-653.
42. Margalit, Y., Yarus, S., Shapira, E., Gruenbaum, Y. & Fainsod, A. (1993) Nucleic Acids Res. 21, 4915-4922.
43. Sauvageau, G., Thorsteinsdottir, U., Hough, M. R., Hugo, P., Lawrence, H. J., Largman, C. & Humphries, R. K. (1997) Immunity 6, 13-22.
44. Taylor, J. K., Levy, T., Suh, E. R. & Traber, P. G. (1997) Nucleic Acids Res. 25, 2293-2300.
45. Houde, M., Laprise, P., Jean, D., Blais, M., Asselin, C. & Rivard, N. (2001)J. Biol. Chem. 276, 21885-21894.
46. Nucifora, G. (1997) Leukemia 11, 2022-2031.