Sp1 transcription factor interaction with accumulated prelamin A impairs adipose lineage differentiation in human mesenchymal stem cells: Essential role of Sp1 in the integrity of lipid vesicles

Stem Cells Translational Medicine

Volumn 1, Issue 4, 2012, Pages 309-321

  de Eguino, Garbiñe Ruiz ^a   Infante, Arantza ^a   Schlangen, Karin ^b   Aransay, Ana M ^b   Fullaondo, Ane ^b   Soriano, Mario ^c   García Verdugo, José Manuel ^d   Martín, Ángel G ^e   Rodríguez, Clara I ^a  

^a BIOCRUCES BIZKAIA HEALTH RESEARCH INSTITUTE   (Spain)

^b CIC BIOGUNE   (Spain)

^c CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^d UNIVERSITY OF VALENCIA   (Spain)

^e Cell Reprogramming Unit   (Spain)

Author keywords

Adipogenesis; Differentiation; Experimental models; Mesenchymal stem cells; Transcription factor

Indexed keywords

3', 3' N XYLENYLBIS (DAUNORUBICIN); BETA GALACTOSIDASE; LAMIN A; PRELAMIN A; TIPRANAVIR; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; NUCLEAR PROTEIN; PROTEIN PRECURSOR;

ADIPOGENESIS; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CHROMATIN; CONTROLLED STUDY; DOWN REGULATION; ELECTRON MICROSCOPY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; LIPID VESICLE; LIPODYSTROPHY; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; PHENOTYPE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ADIPOSE TISSUE; BIOSYNTHESIS; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; LIPID METABOLISM; MESENCHYMAL STROMA CELL; METABOLISM; MUTATION; PATHOLOGY; PHYSIOLOGY; SECRETORY VESICLE;

ADIPOGENESIS; ADIPOSE TISSUE; CELL DIFFERENTIATION; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HUMANS; LIPID METABOLISM; LIPODYSTROPHY; MESENCHYMAL STROMAL CELLS; MUTATION; NUCLEAR PROTEINS; PROTEIN PRECURSORS; SECRETORY VESICLES; SP1 TRANSCRIPTION FACTOR;

EID: 84873730295     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2011-0010     Document Type: Article

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