Failure of lamin A/C to functionally assemble in R482L mutated familial partial lipodystrophy fibroblasts: Altered intermolecular interaction with emerin and implications for gene transcription

Experimental Cell Research

Volumn 291, Issue 1, 2003, Pages 122-134

  Capanni, Cristina ^b   Cenni, Vittoria ^b   Mattioli, Elisabetta ^b   Sabatelli, Patrizia ^a   Ognibene, Andrea ^b   Columbaro, Marta ^b   Parnaik, Veena K ^c   Wehnert, Manfred ^d   Maraldi, Nadir M ^a,b   Squarzoni, Stefano ^a   Lattanzi, Giovanna ^a  

^a CNR   (Italy)

^b RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^c CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^d UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Chromatin disorganization; Familial partial lipodystrophy; Gene transcription; Intranuclear lamin A C speckles; Lamin A C; Lamin emerin interaction

Indexed keywords

DNA; EMERIN; INSULIN; LAMIN A; LAMIN C; RNA; URIDINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DNA STRUCTURE; FAMILIAL DISEASE; FIBROBLAST CULTURE; GENE MUTATION; GENETIC TRANSCRIPTION; GENOME ANALYSIS; HETEROZYGOTE; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; LIPODYSTROPHY; MOLECULAR INTERACTION; MORPHOLOGICAL TRAIT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA SPLICING; RNA TRANSCRIPTION;

EID: 0242365630     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4827(03)00395-1     Document Type: Article

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