Estrogen receptor alpha genotype confers interindividual variability of response to estrogen and testosterone in mesenchymal-stem-cell-derived osteoblasts

Bone

Volumn 39, Issue 5, 2006, Pages 1026-1034

  Leskelä, Hannu Ville ^a   Olkku, Anu ^b   Lehtonen, Siri ^a   Mahonen, Anitta ^b   Koivunen, Jussi ^a   Turpeinen, Miia ^a   Uusitalo, Jouko ^a   Pelkonen, Olavi ^a   Kangas, Lauri ^c   Selander, Katri ^d   Lehenkari, Petri ^a  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c Hormos Medical Ltd   (Finland)

^d University of Alabama at Birmingham   (United States)

Author keywords

Estrogen receptor alpha; Mesenchymal stem cells; Osteoblasts; Polymorphism; Sex steroids

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; TESTOSTERONE;

ADULT; AGED; ALLELE; ARTICLE; CALCIFICATION; CELL ACTIVITY; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MESENCHYMAL STEM CELL; OSTEOBLAST; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEX DIFFERENCE;

17-HYDROXYSTEROID DEHYDROGENASES; ADULT; AGED; AGED, 80 AND OVER; AROMATASE; CELL DIFFERENTIATION; CELLS, CULTURED; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MESENCHYMAL STEM CELLS; MIDDLE AGED; OSTEOBLASTS; OSTEOGENESIS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TESTOSTERONE;

EID: 33749510640     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.05.003     Document Type: Article

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