Design and synthesis of some new quinazolin-4-(3H)-ones as anticonvulsant and antidepressant agents

Archives of Pharmacal Research

Volumn 36, Issue 1, 2013, Pages 61-68

  Amir, Mohd ^a   Ali, Israr ^a   Hassan, Mohd Zaheen ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Anticonvulsant; Antidepressant; GABA; Quinazolinone; Schiff base

Indexed keywords

2 PHENYL 3 [(4 PROPOXYBENZYLIDENE)AMINO] 3H QUINAZOLIN 4 ONE; 2 PHENYL 3 [[4 (2 OXO 2 PHENYLETHOXY)BENZYLIDENE]AMINO] 3H QUINAZOLIN 4 ONE; 3 [(4 ALLYLOXYBENZYLIDENE)AMINO] 2 PHENYL 3H QUINAZOLIN 4 ONE; 3 [(4 BENZYLOXYBENZYLIDENE)AMINO] 2 PHENYL 3H QUINAZOLIN 4 ONE; 3 [(4 BUTOXYBENZYLIDENE)AMINO] 2 PHENYL 3H QUINAZOLIN 4 ONE; 3 [(4 ETHOXYBENZYLIDENE)AMINO] 2 PHENYL 3H QUINAZOLIN 4 ONE; 3 [(4 ISO PROPOXYBENZYLIDENE)AMINO] 2 PHENYL 3H QUINAZOLIN 4 ONE; 3 [(4 METHOXYBENZYLIDENE)AMINO] 2 PHENYL 3H QUINAZOLIN 4 ONE; 3 [[4 [2 (4 FLUOROPHENYL) 2 OXO ETHOXY]BENZYLIDENE]AMINO] 2 PHENYL 3H QUINAZOLIN 4 ONE; 3 [[4 [2 (4 METHOXYPHENYL) 2 OXO ETHOXY]BENZYLIDENE]AMINO] 2 PHENYL 3H QUINAZOLIN 4 ONE; 3 [[4 [2 (4 NITROPHENYL) 2 OXO ETHOXY]BENZYLIDENE]AMINO] 2 PHENYL 3H QUINAZOLIN 4 ONE; 4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; CLOBAZAM; FLUOXETINE; PENTETRAZOLE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID BRAIN LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ANTIDEPRESSANT ACTIVITY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; CONVULSION; DEPRESSION; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MOUSE; NEUROTOXICITY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; ANTICONVULSANTS; ANTIDEPRESSIVE AGENTS; BRAIN; DISEASE MODELS, ANIMAL; DRUG DESIGN; GAMMA-AMINOBUTYRIC ACID; MICE; MOLECULAR STRUCTURE; QUINAZOLINES; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP; SWIMMING;

EID: 84873714877     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-013-0004-y     Document Type: Article

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