DOX-loaded PEG-PLGA and pluronic copolymer composite micelles enhances cytotoxicity and the intracellular accumulation of drug in DOX-resistant tumor cells

Pharmazie

Volumn 65, Issue 5, 2010, Pages 355-357

  Diao, Yuan Yuan ^a,b   Han, Min ^b   Ding, Ping Tian ^a   Chen, Da Wei ^a   Gao, Jian Qing ^b  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COPOLYMER; DOXORUBICIN; MACROGOL; POLYGLACTIN; SOLVENT;

ARTICLE; CELL STRAIN K 562; CYTOTOXICITY; ENCAPSULATION; EVAPORATION; HUMAN; HUMAN CELL; LEUKEMIA; MICELLE; MULTIDRUG RESISTANCE; TUMOR CELL LINE;

EID: 77953044216     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2010.9328     Document Type: Article

References (14)

1. Aroui S, Brahim S, Hamelin J, De Waard M, Bréard J, Kenani A (2009) Conjugation of doxorubicin to cell penetrating peptides sensitizes human breast MDA-MB 231 cancer cells to endogenous TRAIL-induced apoptosis. Apoptosis 14: 1352-1365.
2. Batrakova EV, Li S, Elmquist WF, Miller DW, Alakhov VY, Kabanov AV (2001) Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion. Br J Cancer 85: 1987-1997. (Pubitemid 34775338)
3. Chen JN, Shen Q, Li SS (2009) [Progress in the study of drug delivery system based on nanoparticles to overcome multi-drug resistance]. Yao Xue Xue Bao 44: 333-337.
4. Chen VY, Posada MM, Zhao L, Rosania GR (2007) Rapid doxorubicin efflux from the nucleus of drug-resistant cancer cells following extracellular drug clearance. Pharm Res 24: 2156-2167. (Pubitemid 47493579)
5. Damiani D, Michelutti A, Michieli M, Masolini P, Stocchi R, Geromin A, Ermacora A, Russo D, Fanin R, Baccarani M (2002) P-glycoprotein, lung resistance-related protein and multidrug resistance-associated protein in de novo adult acute lymphoblastic leukaemia. Br J Haematol 116: 519-527. (Pubitemid 34178650)
6. Dudeja PK, Anderson KM, Harris JS, Buckingham L, Coon JS (1995) Reversal of multidrug resistance phenotype by surfactants: relationship to membrane lipid fluidity. Arch Biochem Biophys 319: 309-315.
7. Jabr-Milane LS, van Vlerken LE, Yadav S, Amiji MM (2008) Multi-functional nanocarriers to overcome tumor drug resistance. Cancer Treat Rev 34: 592-602.
8. Kabanov AV, Batrakova EV, Alakhov VY (2002) Pluronic block copolymers for overcoming drug resistance in cancer. Adv Drug Deliv Rev 54: 759-779.
9. Lukyanova NY, Rusetskya NV, Tregubova NA, Chekhun VF (2009) Molecular profile and cell cycle in MCF-7 cells resistant to cisplatin and doxorubicin. Exp Oncol 31: 87-91.
10. Minko T, Batrakova EV, Li S, Li Y, Pakunlu RI, Alakhov VY, Kabanov AV (2005) Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells. J Control Release 105: 269-278. (Pubitemid 40941992)
11. Shi YQ, Qu XJ, Liao YX, Xie CF, Cheng YN, Li S, Lou HX (2008) Reversal effect of a macrocyclic bisbibenzyl plagiochin E on multidrug resistance in adriamycin-resistant K562/A02 cells. Eur J Pharmacol 584: 66-71.
12. Shuai X, Ai H, Nasongkla N, Kim S, Gao J (2004) Micellar carriers based on block copolymers of poly(epsilon-caprolactone) and poly(ethylene glycol) for doxorubicin delivery. J Control Release 98: 415-426. (Pubitemid 39093952)
13. Venne A, Li S, Mandeville R, Khabanov A, Alakhov V (1996) Hypersensitizing effect of pluronic L61 on cytotoxic activity, transport, and subcellular distribution of doxorubicin in multiple drug-resistant cells. Cancer Res 56: 3626-3629.
14. Xu P, Tang H, Li S, Ren J, Van Kirk E, Murdoch WJ, Radosz M, Shen Y (2004) Enhanced stability of core-surface cross-linked micelles fabricated from amphiphilic brush copolymers. Biomacromolecules 5: 1736-1744. (Pubitemid 39335209)