N-alkylation of poloxamines modulates micellar assembly and encapsulation and release of the antiretroviral efavirenz

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 76, Issue 1, 2010, Pages 24-37

  Chiappetta, Diego A ^a,b   Alvarez Lorenzo, Carmen ^c   Rey Rico, Ana ^c   Taboada, Pablo ^c   Concheiro, Angel ^c   Sosnik, Alejandro ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Drug release; Efavirenz encapsulation; HIV AIDS; Polymeric micelles; Pristine and N alkylated poloxamines self assembly

Indexed keywords

EFAVIRENZ; NANOCARRIER; POLOXAMINE; UNCLASSIFIED DRUG;

ALKYLATION; ALLYLATION; ANIMAL CELL; AQUEOUS SOLUTION; ARTICLE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG RELEASE; ENCAPSULATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYDROPHILICITY; IN VITRO STUDY; METHYLATION; MICELLIZATION; MOLECULAR WEIGHT; MOUSE; NONHUMAN;

EID: 77955665042     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.05.007     Document Type: Article

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