Conventional liquid chromatography/triple quadrupole mass spectrometry based metabolite identification and semi-quantitative estimation approach in the investigation of in vitro dabigatran etexilate metabolism

Analytical and Bioanalytical Chemistry

Volumn 405, Issue 5, 2013, Pages 1695-1704

  Hu, Zhe Yi ^a   Parker, Robert B ^a   Herring, Vanessa L ^a   Laizure, S Casey ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Carboxylesterase; Dabigatran etexilate; Liquid chromatography; Mass spectrometer; Metabolism

Indexed keywords

BIOMOLECULES; ENZYMES; ESTERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLISM;

CARBOXYLESTERASES; DABIGATRAN ETEXILATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY/MASS SPECTROMETRIES; METABOLITE IDENTIFICATION; QUADRUPOLE MASS SPECTROMETRY; QUANTITATIVE ESTIMATION; QUANTITATIVE INFORMATION; TRIPLE-QUADRUPOLE MASS SPECTROMETRY;

METABOLITES;

EID: 84873702919     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-012-6576-4     Document Type: Article

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