Centrosomal localization of RhoGDIβ and its relevance to mitotic processes in cancer cells

International Journal of Oncology

Volumn 42, Issue 2, 2013, Pages 460-468

  Jiang, Yong Sheng ^a,c   Maeda, Masayo ^a   Okamoto, Mayumi ^b   Fujii, Mikiko ^b   Fukutomi, Ryuichiro ^b   Hori, Masato ^b   Tatsuka, Masaaki ^b   Ota, Takahide ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

^b PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Cancer progression; Centrosome; Cytokinesis; Rho GDP dissociation inhibitor

Indexed keywords

RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR 2; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE REGULATION; CELL SHAPE; CELLULAR DISTRIBUTION; CENTROSOME; CONTROLLED STUDY; CYTOKINESIS; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; MITOSIS; MITOSIS SPINDLE; MOUSE; NONHUMAN; POLYPLOIDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RNA INTERFERENCE;

CENTROSOME; CYTOKINESIS; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; MITOSIS; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR BETA; RNA INTERFERENCE; SPINDLE APPARATUS;

EID: 84873669360     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2012.1730     Document Type: Article

References (52)

1. Etienne-Manneville S and Hall A: Rho GTPases in cell biology. Nature 420: 629-635, 2002.
2. Wennerberg K and Der CJ: Rho-family GTPases: it's not only Rac and Rho (and I like it). J Cell Sci 117: 1301-1312, 2004.
3. Rossman KL, Der CJ and Sondek J: GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol 6: 167-180, 2005.
4. Tcherkezian J and Lamarche-Vane N: Current knowledge of the large RhoGAP family of proteins. Biol Cell 99: 67-86, 2007.
5. Dovas A and Couchman JR: RhoGDI: multiple functions in the regulation of Rho family GTPase activities. Biochem J 390: 1-9, 2005.
6. DerMardirossian C and Bokoch GM: GDIs: central regulatory molecules in Rho GTPase activation. Trends Cell Biol 15: 356-363, 2005.
7. Dransart E, Olofsson B and Cherfils J: RhoGDIs revisited: novel roles in Rho regulation. Traffic 6: 957-966, 2005.
8. Garcia-Mata R, Boulter E and Burridge K: The 'invisible hand': regulation of RHO GTPases by RHOGDIs. Nat Rev Mol Cell Biol 12: 493-504, 2011.
9. Adra CN, Manor D, Ko JL, et al: RhoGDI?: a GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas. Proc Natl Acad Sci USA 94: 4279-4284, 1997.
10. Zalcman G, Closson V, Camonis J, et al: RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG. J Biol Chem 271: 30366-30374, 1996.
11. Lelias JM, Adra CN, Wulf GM, et al: cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP binding proteins. Proc Natl Acad Sci USA 90: 1479-1483, 1993.
12. Scherle P, Behrens T and Staudt LM: Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes. Proc Natl Acad Sci USA 90: 7568-7572, 1993.
13. Leffers H, Nielsen MS, Andersen AH, et al: Identification of two human Rho GDP dissociation inhibitor proteins whose overexpression leads to disruption of the actin cytoskeleton. Exp Cell Res 209: 165-174, 1993.
14. Gildea JJ, Seraj MJ, Oxford G, et al: RhoGDI2 is an invasion and metastasis suppressor gene in human cancer. Cancer Res 62: 6418-6423, 2002.
15. Ota T, Maeda M, Suto S and Tatsuka M: LyGDI functions in cancer metastasis by anchoring Rho proteins to the cell membrane. Mol Carcinog 39: 206-220, 2004.
16. Seraj MJ, Harding MA, Gildea JJ, Welch DR and Theodorescu D: The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines. Clin Exp Metastasis 18: 519-525, 2001.
17. Theodorescu D, Sapinoso LM, Conaway MR, Oxford G, Hampton GM and Frierson HF Jr: Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer. Clin Cancer Res 10: 3800-3806, 2004.
18. Tapper J, Kettunen E, El-Rifai W, Seppala M, Andersson LC and Knuutila S: Changes in gene expression during progression of ovarian carcinoma. Cancer Genet Cytogenet 128: 1-6, 2001.
19. Zhang Y and Zhang B: D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness. Cancer Res 66: 5592-5598, 2006.
20. Cho HJ, Baek KE, Park SM, et al: RhoGDI2 expression is associated with tumor growth and malignant progression of gastric cancer. Clin Cancer Res 15: 2612-2619, 2009.
21. Abiatari I, DeOliveira T, Kerkadze V, et al: Consensus transcriptome signature of perineural invasion in pancreatic carcinoma. Mol Cancer Ther 8: 1494-1504, 2009.
22. Koide N, Yamada T, Shibata R, et al: Establishment of perineural invasion models and analysis of gene expression revealed an invariant chain (CD74) as a possible molecule involved in perineural invasion in pancreatic cancer. Clin Cancer Res 12: 2419-2426, 2006.
23. Zhang Y, Rivera Rosado LA, Moon SY and Zhang B: Silencing of D4-GDI inhibits growth and invasive behavior in MDA MB 231 cells by activation of Rac-dependent p38 and JNK signaling. J Biol Chem 284: 12956-12965, 2009.
24. Ota T, Maeda M, Murakami M, Takegami T, Suto S and Tatsuka M: Activation of Rac1 by Rho-guanine nucleotide dissociation inhibitor-ß with defective isoprenyl-binding pocket. Cell Biol Int 31: 92-96, 2007.
25. Ota T, Maeda M, Sakita-Suto S, et al: RhoGDIß lacking the N-terminal regulatory domain suppresses metastasis by promoting anoikis in v-src-transformed cells. Clin Exp Metastasis 23: 323-334, 2006.
26. Wu Y, Moissoglu K, Wang H, et al: Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function. Proc Natl Acad Sci USA 106: 5807-5812, 2009.
27. Moissoglu K, McRoberts KS, Meier JA, Theodorescu D and Schwartz MA: Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. Cancer Res 69: 2838-2844, 2009.
28. Scherer WF, Syverton JT and Gey GO: Studies on the propagation in vitro of poliomyelitis viruses. IV. Viral multiplication in a stable strain of human malignant epithelial cells (strain HeLa) derived from an epidermoid carcinoma of the cervix. J Exp Med 97: 695-710, 1953.
29. Leibovitz A, Stinson JC, McCombs WB III, McCoy CE, Mazur KC and Mabry ND: Classification of human colorectal adenocarcinoma cell lines. Cancer Res 36: 4562-4569, 1976.
30. Dickson MA, Hahn WC, Ino Y, et al: Human keratinocytes that express hTERT and also bypass a p16INK4a-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol 20: 1436-1447, 2000.
31. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
32. Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA and Mann M: Proteomic characterization of the human centrosome by protein correlation profiling. Nature 426: 570-574, 2003.
33. Narumiya S and Yasuda S: Rho GTPases in animal cell mitosis. Curr Opin Cell Biol 18: 199-205, 2006.
34. Piekny A, Werner M and Glotzer M: Cytokinesis: welcome to the Rho zone. Trends Cell Biol 15: 651-658, 2005.
35. Ban R, Irino Y, Fukami K and Tanaka H: Human mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity towards Cdc42 during the metaphase. J Biol Chem 279: 16394-16402, 2004.
36. Woodcock SA, Rushton HJ, Castaneda-Saucedo E, et al: Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression. Curr Biol 20: 669-675, 2010.
37. Weaver BA and Cleveland DW: Does aneuploidy cause cancer? Curr Opin Cell Biol 18: 658-667, 2006.
38. Tillement V, Remy MH, Raynaud-Messina B, Mazzolini L, Haren L and Merdes A: Spindle assembly defects leading to the formation of a monopolar mitotic apparatus. Biol Cell 101: 1-11, 2009.
39. Vaughan S and Dawe HR: Common themes in centriole and centrosome movements. Trends Cell Biol 21: 57-66, 2011.
40. Feigin ME and Muthuswamy SK: Polarity proteins regulate mammalian cell-cell junctions and cancer pathogenesis. Curr Opin Cell Biol 21: 694-700, 2009.
41. Knoblich JA: Asymmetric cell division: recent developments and their implications for tumour biology. Nat Rev Mol Cell Biol 11: 849-860, 2010.
42. Lee M and Vasioukhin V: Cell polarity and cancer - cell and tissue polarity as a non-canonical tumor suppressor. J Cell Sci 121: 1141-1150, 2008.
43. Fischer AH, Zhao C, Li QK, et al: The cytologic criteria of malignancy. J Cell Biochem 110: 795-811, 2010.
44. Iden S and Collard JG: Crosstalk between small GTPases and polarity proteins in cell polarization. Nat Rev Mol Cell Biol 9: 846-859, 2008.
45. Carol RJ, Takeda S, Linstead P, et al: A RhoGDP dissociation inhibitor spatially regulates growth in root hair cells. Nature 438: 1013-1016, 2005.
46. Court H and Sudbery P: Regulation of Cdc42 GTPase activity in the formation of hyphae in Candida albicans. Mol Biol Cell 18: 265-281, 2007.
47. Imai K, Kijima T, Noda Y, Sutoh K, Yoda K and Adachi H: A Rho GDP-dissociation inhibitor is involved in cytokinesis of Dictyostelium. Biochem Biophys Res Commun 296: 305-312, 2002.
48. Price MS, Nichols CB and Alspaugh JA: The Cryptococcus neoformans Rho-GDP dissociation inhibitor mediates intracellular survival and virulence. Infect Immun 76: 5729-5737, 2008.
49. Richman TJ, Toenjes KA, Morales SE, et al: Analysis of cell-cycle specific localization of the Rdi1p RhoGDI and the structural determinants required for Cdc42p membrane localization and clustering at sites of polarized growth. Curr Genet 45: 339-349, 2004.
50. Rivero F, Illenberger D, Somesh BP, Dislich H, Adam N and Meyer AK: Defects in cytokinesis, actin reorganization and the contractile vacuole in cells deficient in RhoGDI. EMBO J 21: 4539-4549, 2002.
51. Yap SF, Chen W and Lim L: Molecular characterization of the Caenorhabditis elegans Rho GDP-dissociation inhibitor. Eur J Biochem 266: 1090-1100, 1999.
52. Menotta M, Amicucci A, Basili G, Polidori E, Stocchi V and Rivero F: Molecular and functional characterization of a Rho GDP dissociation inhibitor in the filamentous fungus Tuber borchii. BMC Microbiol 8: 57, 2008.