-
1
-
-
0037264812
-
Metastasis suppressors alter the signal transduction of cancer cells
-
Steeg PS. Metastasis suppressors alter the signal transduction of cancer cells. Nat Rev Cancer 2003;3: 55-63.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 55-63
-
-
Steeg, P.S.1
-
3
-
-
0038556694
-
Tumor progression: Small GTPases and loss of cell-cell adhesion
-
Lozano E, Betson M, Braga VM. Tumor progression: small GTPases and loss of cell-cell adhesion. Bioes- says 2003;25:452 -63.
-
(2003)
Bioes- says
, vol.25
, pp. 452-463
-
-
Lozano, E.1
Betson, M.2
Braga, V.M.3
-
5
-
-
23944518413
-
RhoGDI: Multiple functions in the regulation of Rho family GTPase activities
-
Dovas A, Couchman JR. RhoGDI: multiple functions in the regulation of Rho family GTPase activities. Bio- chemJ 2005;390:1 -9.
-
(2005)
Bio- chemJ
, vol.390
, pp. 1-9
-
-
Dovas, A.1
Couchman, J.R.2
-
6
-
-
21744432683
-
GDIs: Central regulatory moleculesin Rho GTPase activation
-
DerMardirossian C, Bokoch GM. GDIs: central regulatory moleculesin Rho GTPase activation. Trends Cell Biol 2005;15:356 -63.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 356-363
-
-
DerMardirossian, C.1
Bokoch, G.M.2
-
7
-
-
0026496258
-
A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs
-
Hart MJ, Maru Y, Leonard D, Witte ON, Evans T, Cerione RA. A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs. Science 1992;258:812 -5.
-
(1992)
Science
, vol.258
, pp. 812-815
-
-
Hart, M.J.1
Maru, Y.2
Leonard, D.3
Witte, O.N.4
Evans, T.5
Cerione, R.A.6
-
8
-
-
0027393663
-
GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein
-
Chuang TH, Xu X, Knaus UG, Hart MJ, Bokoch GM. GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein. J Biol Chem 1993; 268:775-8.
-
(1993)
J Biol Chem
, vol.268
, pp. 775-778
-
-
Chuang, T.H.1
Xu, X.2
Knaus, U.G.3
Hart, M.J.4
Bokoch, G.M.5
-
9
-
-
0025073547
-
Molecularcloning and characterization ofa novel type ofregulatory protein (GDI) for the Rho proteins, ras p21-like small GTP-bindingproteins
-
Fukomoto Y, Kaibuchi K, Hori Y, et al. Molecularcloning and characterization ofa novel type ofregulatory protein (GDI) for the Rho proteins, ras p21-like small GTP-bindingproteins. Oncogene1990;5:1321 -8.
-
Oncogene1990;5
, pp. 1321-1328
-
-
Fukomoto, Y.1
Kaibuchi, K.2
Hori, Y.3
-
10
-
-
0027237511
-
-
Scherle P, Behrens T, Staudt LM. Ly-GDI, a GDP- dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes. Proc Natl Acad Sci U S A1993;90:7568-72.
-
Scherle P, Behrens T, Staudt LM. Ly-GDI, a GDP- dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes. Proc Natl Acad Sci U S A1993;90:7568-72.
-
-
-
-
11
-
-
0029828539
-
RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG
-
Zalcman G, Closson V, CamonisJ, et al. RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG. J Biol Chem 1996;271:30366 -74.
-
(1996)
J Biol Chem
, vol.271
, pp. 30366-30374
-
-
Zalcman, G.1
Closson, V.2
CamonisJ3
-
12
-
-
0027526303
-
cDNAcloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissocia- tion inhibitor for the rho GTP-binding proteins
-
Lelias JM, Adra CN,Wulf GM, et al. cDNAcloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissocia- tion inhibitor for the rho GTP-binding proteins. Proc Natl Acad Sci U S A1993;90:1479 -83.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1479-1483
-
-
Lelias, J.M.1
Adra, C.N.2
Wulf, G.M.3
-
13
-
-
0030611196
-
RhoGDIγ:a GDP- dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas
-
Adra CN, Manor D, Ko JL, et al. RhoGDIγ:a GDP- dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas. Proc Natl Acad Sci U S A1997;94:4279 -84.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 4279-4284
-
-
Adra, C.N.1
Manor, D.2
Ko, J.L.3
-
14
-
-
0036210918
-
Proteomicanal- ysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer
-
Jones MB, Krutzsch H, Shu H, et al. Proteomicanal- ysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer. Proteomics 2002;2:76 -84.
-
(2002)
Proteomics
, vol.2
, pp. 76-84
-
-
Jones, M.B.1
Krutzsch, H.2
Shu, H.3
-
15
-
-
0037048326
-
Rho GTPases in human breast tumours: Expression and mutation analyses and correlation with clinical parameters
-
Fritz G, Brachetti C, Bahlmann F, Schmidt M, Kaina B. Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters. Br J Cancer 2002;87:635-44.
-
(2002)
Br J Cancer
, vol.87
, pp. 635-644
-
-
Fritz, G.1
Brachetti, C.2
Bahlmann, F.3
Schmidt, M.4
Kaina, B.5
-
16
-
-
0347594125
-
Prognostic value of Rho GTPases and Rho guanine nucleotide dissociation inhibitors in human breast cancers
-
Jiang WG,Watkins G, Lane J, et al. Prognostic value of Rho GTPases and Rho guanine nucleotide dissociation inhibitors in human breast cancers. Clin Cancer Res 2003;9:6432-40.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 6432-6440
-
-
Jiang, W.G.1
Watkins, G.2
Lane, J.3
-
17
-
-
0035397380
-
Changes in gene expression during progression of ovarian carcinoma
-
Tapper J, Kettunen E, El-Rifai W, Seppala M, Andersson LC, Knuutila S. Changes in gene expression during progression of ovarian carcinoma. Cancer Genet Cytogenet 2001;128:1 -6.
-
(2001)
Cancer Genet Cytogenet
, vol.128
, pp. 1-6
-
-
Tapper, J.1
Kettunen, E.2
El-Rifai, W.3
Seppala, M.4
Andersson, L.C.5
Knuutila, S.6
-
18
-
-
33745233810
-
D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness
-
ZhangY, Zhang B. D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness. Cancer Res 2006;66:5592 -8.
-
(2006)
Cancer Res
, vol.66
, pp. 5592-5598
-
-
Zhang, Y.1
Zhang, B.2
-
19
-
-
0037112363
-
RhoGDI2 is an invasion and metastasis suppressor gene in human cancer
-
Gildea JJ, Seraj MJ, Oxford G, et al. RhoGDI2 is an invasion and metastasis suppressor gene in human cancer. Cancer Res 2002;62:6418-23.
-
(2002)
Cancer Res
, vol.62
, pp. 6418-6423
-
-
Gildea, J.J.1
Seraj, M.J.2
Oxford, G.3
-
20
-
-
2542606977
-
Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer
-
Theodorescu D, Sapinoso LM, Conaway MR, Oxford G, Hampton GM, Frierson HF, Jr. Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer. Clin Cancer Res 2004;10:3800-6.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3800-3806
-
-
Theodorescu, D.1
Sapinoso, L.M.2
Conaway, M.R.3
Oxford, G.4
Hampton, G.M.5
Frierson Jr, H.F.6
-
21
-
-
33750742433
-
Overexpression of nicotinamide N-methyltransferase in gastric cancer tissues and its potential post-transla- tional modification
-
Lim BH, Cho BI, KimYN, Kim JW, Park ST, Lee CW. Overexpression of nicotinamide N-methyltransferase in gastric cancer tissues and its potential post-transla- tional modification. Exp Mol Med 2006;38:455 -65.
-
(2006)
Exp Mol Med
, vol.38
, pp. 455-465
-
-
Lim, B.H.1
Cho, B.I.2
Kim, Y.N.3
Kim, J.W.4
Park, S.T.5
Lee, C.W.6
-
22
-
-
0025321564
-
Characteristics of cell lines established from human gastric carcinoma
-
Park JG, Frucht H, LaRocca RV, et al. Characteristics of cell lines established from human gastric carcinoma. Cancer Res1990;50:2773 -80.
-
Cancer Res1990;50
, pp. 2773-2780
-
-
Park, J.G.1
Frucht, H.2
LaRocca, R.V.3
-
23
-
-
0031038107
-
Establishment and characterization of human gastric carcinoma cell lines
-
Park JG,Yang HK, Kim WH, et al. Establishment and characterization of human gastric carcinoma cell lines. IntJ Cancer1997;70:443 -9.
-
IntJ Cancer1997
, vol.70
, pp. 443-449
-
-
Park, J.G.1
Yang, H.K.2
Kim, W.H.3
-
24
-
-
0042134847
-
Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasmino- gen activator system
-
Lee DH, Yang Y, Lee SJ, et al. Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasmino- gen activator system. Cancer Res 2003;63:4648-55.
-
(2003)
Cancer Res
, vol.63
, pp. 4648-4655
-
-
Lee, D.H.1
Yang, Y.2
Lee, S.J.3
-
26
-
-
0030869004
-
Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases
-
Yin L, Schwartzberg P, Scharton-Kersten TM, Staudt L, Lenardo M. Immune responses in mice deficient in Ly-GDI, a lymphoid-specific regulator of Rho GTPases. Mol Immunol 1997;34:484-91.
-
(1997)
Mol Immunol
, vol.34
, pp. 484-491
-
-
Yin, L.1
Schwartzberg, P.2
Scharton-Kersten, T.M.3
Staudt, L.4
Lenardo, M.5
-
27
-
-
0034842795
-
The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines
-
Seraj MJ, Harding MA, Gildea JJ, Welch DR, Theodorescu D. The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines. Clin Exp Metastasis 2000;18:519 -25.
-
(2000)
Clin Exp Metastasis
, vol.18
, pp. 519-525
-
-
Seraj, M.J.1
Harding, M.A.2
Gildea, J.J.3
Welch, D.R.4
Theodorescu, D.5
-
29
-
-
0027391509
-
Involvementof Rho p21 and its inhibitory GDP/GTP exchange protein (RhoGDI) in cell motility
-
Takaishi K, Kikuchi A, Kuroda S, et al. Involvementof Rho p21 and its inhibitory GDP/GTP exchange protein (RhoGDI) in cell motility. Mol Cell Biol 1993;13:72-9.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 72-79
-
-
Takaishi, K.1
Kikuchi, A.2
Kuroda, S.3
-
30
-
-
0028226187
-
The GDP- bound form of the small G protein Rac1 p21is a potent activator of the superoxide-forming NADPH oxidase of macrophages
-
Bromberg Y, Shani E, Joseph G, et al. The GDP- bound form of the small G protein Rac1 p21is a potent activator of the superoxide-forming NADPH oxidase of macrophages. J Biol Chem 1994;269:7055 -8.
-
(1994)
J Biol Chem
, vol.269
, pp. 7055-7058
-
-
Bromberg, Y.1
Shani, E.2
Joseph, G.3
-
31
-
-
0042761752
-
RhoGDI is required for Cdc42-mediated cellular transformation
-
Lin Q, Fuji RN, Yang W, Cerione RA. RhoGDI is required for Cdc42-mediated cellular transformation. Curr Biol 2003;13:1469 -79.
-
(2003)
Curr Biol
, vol.13
, pp. 1469-1479
-
-
Lin, Q.1
Fuji, R.N.2
Yang, W.3
Cerione, R.A.4
-
32
-
-
0037147241
-
Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducer inTcell antigen receptor-induced pathways
-
Groysman M, Hornstein I, Alcover A, Katzav S.Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducer inTcell antigen receptor-induced pathways. J Biol Chem 2002;277: 50121 -30.
-
(2002)
J Biol Chem
, vol.277
, pp. 50121-50130
-
-
Groysman, M.1
Hornstein, I.2
Alcover, A.3
Katzav, S.4
-
33
-
-
36348938027
-
Cyclooxy- genase-2 is a targetgene of Rho GDP dissociation inhibitor h in breast cancer cells
-
Schunke D, Span P, Ronneburg H, et al. Cyclooxy- genase-2 is a targetgene of Rho GDP dissociation inhibitor h in breast cancer cells. Cancer Res 2007;67: 10694-702.
-
(2007)
Cancer Res
, vol.67
, pp. 10694-10702
-
-
Schunke, D.1
Span, P.2
Ronneburg, H.3
-
34
-
-
33744948986
-
NFAT induces breast cancer cell invasion by promoting the induction of cyclooxyge-nase-2
-
Yiu GK,TokerA. NFAT induces breast cancer cell invasion by promoting the induction of cyclooxyge-nase-2. J Biol Chem 2006;281:12210-7.
-
(2006)
J Biol Chem
, vol.281
, pp. 12210-12217
-
-
Yiu, G.K.1
Toker, A.2
-
35
-
-
33748358343
-
Inhibition ofcyclooxygenase-2 decreases breast cancer cell motility, invasion and matrix metalloproteinase expression
-
LarkinsTL, Nowell M, Singh S, Sanford GL. Inhibition ofcyclooxygenase-2 decreases breast cancer cell motility, invasion and matrix metalloproteinase expression. BMC Cancer 2006;6:181.
-
(2006)
BMC Cancer
, vol.6
, pp. 181
-
-
Larkins, T.L.1
Nowell, M.2
Singh, S.3
Sanford, G.L.4
-
36
-
-
23144461051
-
-
Minn AJ, Guopta GP, Siegel PM, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005;436:518-24.
-
Minn AJ, Guopta GP, Siegel PM, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005;436:518-24.
-
-
-
-
37
-
-
0032564411
-
Vascularendothelial growth factor C induces angiogenesis in vivo
-
CaoY, Linden P, FarneboJ, et al.Vascularendothelial growth factor C induces angiogenesis in vivo. Proc Natl Acad Sci U S A1998;95:14389-94.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 14389-14394
-
-
Cao, Y.1
Linden, P.2
Farnebo, J.3
-
38
-
-
33644822574
-
The VEGF-C/Flt-4 promotes invasion and metastasis of cancer cells
-
Su JL, Yang PC, Shih JY, et al. The VEGF-C/Flt-4 promotes invasion and metastasis of cancer cells. Cancer Cell 2006;9:209-23.
-
(2006)
Cancer Cell
, vol.9
, pp. 209-223
-
-
Su, J.L.1
Yang, P.C.2
Shih, J.Y.3
-
39
-
-
0030973506
-
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
-
Jeltsch M, Kaipainen A, JoukovV, et al. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science1997;276:1423-5.
-
Science1997;276
, pp. 1423-1425
-
-
Jeltsch, M.1
Kaipainen, A.2
JoukovV3
|