Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK

Gene Therapy

Volumn 20, Issue 2, 2013, Pages 136-142

  Anderson, B R ^a   Kariko K ^a   Weissman, D ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

eIF2 ; GCN2; mRNA therapy; Nucleofection; PERK

Indexed keywords

DNA; GENERAL CONTROL NON DEREPRESSIBLE 2; INITIATION FACTOR 2ALPHA; MESSENGER RNA; PROTEIN KINASE; PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DENDRITIC CELL; ELECTROPORATION; EMBRYO CELL; FIBROBLAST; HUMAN; HUMAN CELL; KNOCKOUT GENE; MAMMAL CELL; NONHUMAN; NUCLEOFECTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ANIMALS; CELL LINE; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2; HUMANS; MICE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; TRANSFECTION;

EUKARYOTA; MAMMALIA;

EID: 84873569635     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2012.5     Document Type: Article

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